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especially in colonic hypermolility. Colospasmln Forte, being entirely a smooth muscle relaxant without atropine-like effects, is not contraindicated in patients with glaucoma or
prostatic hypertrophy.
Pharmacokinetics:
Following oral administration, mebeverine is absorbed from the gastrointestinal tract; peak plasma concentrations are achieved within 1 3 hours after dosing. Mebeverine is about 75%
bound to plasma proteins, and is completely metabolized by hydrolysis to veratric acid and mebeverine alcohol. The metabolites are excreted in the urine.
Indications:
Primary irritable colon characterized by persistent diarrhoea, alternating constipation and diarrhoea, abdominal pain and postprandial distention.
Secondary irritable colon due to organic lesions such as regional enteritis, diverticulitis, specific and non-specific inflammations of the gastrointestinal tract.
Dosage and Administration:
Adults: 1 tablet 3 times daily, preferably before meals.
- Not recommended for children.
Precautions:
* Coloapasmin@Forteshould be used with caution in:
- Patients with marked hepatic or renal impairment.
- Patients with cardiac disorders such as heart block,
- Antispasmodics, including Colospasmlnforte, are not recommended tor the symptomatic treatment of distal intestinal syndrome in cystic fibrosis.
* Though experiments in rats and rabbits have shown mebeverine hydrochloride not to be teratogenic, Coiospasminforte is better avoided during pregnancy.
* Colospasmlnforte is considered to be unsafe in patients with porphyria.
* Treetment of overdoaage: There is no specific antidote; gastric lavage and symptomatic treatment are recommended.
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Contra-indications:
- Hypersensitivity to the product.
- Paralytic ileus.
Side Effects:
Colospasmln@Forte has proved to be well-tolerated In therapeutic doses. The side effects are rare; they may include gastrointestinal distrurbances, dizziness, headache, insomnia, and
depression. In very rare cases allergic reactions have been reported especially erythematous rash. urticaria and angio-eodema.
STORAGE:
Store at temperature not exceeding 30.
Packaging:
Colospasmln@Forte Tablets :Blisters of 10 tablets each.
Colospasmin@Forte Tablets :Boxes of 20 or 1000 tablets;each.
This Is a Medicament :
- Medicament is a product which affects your health, and its consumption contrary to instructions is dangerous for you.
- Follow strictly the doctors prescription, the method of use, and the instructions of the pharmacist who sold the medicament.
- The doctor and the pharmacist are experts in medicine, its benefits and risks.
- Do not by yourself interrupt the period of treatment prescribed.
- D0 not repeat the same prescription without consulting your doctor.
- Keep all medicines out of reach of children.
MANUFACTURED BY :
E.I.P.I.CO.
EGYPTIAN INT. PHARMACEUTICAL INDUSTRIES CO.
TENTH OF RAMADAN CITY,AREA EGYPT ..
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Conaz for diarrhea and dysentery of bacterial, amoebic, or of mixed origin (http://www.medicinep.com/conaz-for-diarrhea-and-dysentery-of-bacterial-amoebic-or-of-mixed-origin1995.html)
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