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M.Sc.entranceclassChapte
erTest:04CellC
CycleandDNAR
Replication

All50questionsareco
ompulsoryandccarryequalmarkks

FullMaarks:100

1.

2.

3.

4.

5.

6.

7.

8.

9.

In
nFig.lwhichoffthesecellsis(are)haploid?
A) AandD
D
B) BandC
C
Fig.l

C) CandD
D
D) None
A diploid organ
nism whose so
omatic (nonseex) cells each contain 32 ch
hromosomes produces
p
gameetes
ontaining____
__chromosomes.
co
A) 32
B) 16
C) 30
D) 64
During_____bo
oththeconten
ntsofthenucleeusandthecyttoplasmaredivvided.
A) Karyokkinesis
B) G1
C) S
D) mitosiss
During_____th
hecellgrowsandreplicatesb
bothitsorganeellesanditschrromosomes.
A) S
nesis
B) cytokin
C) nterphase
D) mitosiss
Nucleoliarepre
esentduring______.
A) interph
hase
B) prophaase
C) promettaphase
D) anaphaase
Cyytokinesisofte
en,butnotalw
ways,accompan
nies_____.
A) telophaase
B) promettaphase
C) anaphaase
D) interph
hase
Ch
hromosomesb
becomevisibleeduring_____..
A) metaph
hase
B) prophaase
C) interph
hase
D) promettaphase
Ceentromeresdivvideandsisterrchromosomesbecomefullffledgedchrom
mosomesduringg_____.
A) metaph
hase
B) promettaphase
C) telophaase
D) anaphaase
Sp
pindlefibersatttachtokineto
ochoresduring_____.
A) metaph
hase
B) promettaphase
C) anaphaase
D) telophaase
ChapterTestt:04CellCycle
eandDNARep
plication Page1of6


10. Duringprophaseahomologouspairofchromosomesconsistsof_____.
A) fourchromosomesandtwochromatids
B) twochromosomesandtwochromatids
C) twochromosomesandfourchromatids
D) onechromosomeandtwochromatids
E) onechromosomeandfourchromatids
11. WhichoftheseisNOTacarcinogen?
A) cigarettesmoke
B) UVlight
C) Radiation
D) alloftheabovearecarcinogens
12. TheG0phaseis
A) thecheckpointbeforeG1
B) thefunctionalstateofmostcellsinananimalbody
C) anothernameforinterphase
D) apermanentstateofallbodycells
13. Theterm"homologouschromosomes"
A) referstoreplicationsofthesamechromosome
B) isanothernameforsisterchromatids
C) mustbehaploid
D) meansapairofchromosomesofthesamekind,suchassexchromosomes.
14. Acentromereis
A) anothernameforkinetochore
B) thestructuretowhichmicrotubulesattach
C) aconstrictiononachromosomeboundtoadisk
D) thepointonthecelltowhichchromosomesmigrate
15. Followingtelophaseinanimalcells,acellplatebeginstoform.
A)
True
B)
False
16. Chromosomereplicationtakesplaceduringinterphase.
A)
True
B)
False
17. Whichphaseofmitosisisassociatedwithformationofthenuclearenvelope?
A)
telophase
B)
prophase
C)
metaphase
D)
anaphase
18. Whichphaseofmitosisisassociatedwithseparationofchromatids?
A)
telophase
B)
prophase
C)
metaphase
D)
anaphase
19. Duringcelldivision,whatstructureformsasanetworkofproteincables?
A)
spindle
B)
chromatid
C)
kinetochore
D)
centromere
20. Whichofthefollowingstatementsaboutmitosisisincorrect?
A)
Thecentrosomesorganizethemicrotubulesofthespindlefibers.

B)
Chromosomes separate during anaphase due to the interaction of polar microtubules
fromoppositepolespushingagainsteachother.
C)
Chromosomes separate during anaphase when the kinetochore microtubules shorten as
theydepolymerize.
D)
Chromosomes move to the metaphase plate using motor proteins, a kind of kinesin,
attachedtospindlefibers.
ChapterTest:04CellCycleandDNAReplicationPage2of6


21. Centriolesareaveryimportantpartof_____________.
A) Centriosome
B) Chromosome
C) Kinetochore
D) none
22. Whichareinvolvedinorganizingmicrotubulesinthecytoplasm?
A) Kinetochore
B) Chromosome
C) Centrioles
D) Centromere
23. Spindle fiber filaments of the cytoskeleton typically form through the polymerization of
_____________,elongatingexistingmicrotubules.
A) andtubulindimers
B) Actinsubunits
C) Globulin
D) Factin
24. Cytosol
A)
hasahighwatercontent,withmanydissolvedsolutes
B)
istheviscous,syruplikefluidcomponentofcytoplasm
C)
containscarbohydratesandlipidsthatprovideenergyforthecell
D)
alloftheabove
25. Whichorganellessynthesizeproteins?
A)
ribosomes
B)
NOR
C)
rRNA
D)
alloftheabove
26. Digestionandselfdestructionarefunctionsofwhichorganelle?
A)
nucleus
B)
mitochondrion
C)
lysosome
D)
peroxisome
27. Whichoneofthefollowingdoesnotaccuratelydescribemicrotubules?
A)
composedoflongchainsoftheproteintubulin
B)
largestdiameterofthethreecomponentsofthecytoskeleton
C)
associatedwithorganellemovementandcellmotility
D)
participateincytoplasmicstreamingandmusclecontraction
28. Mostofacell'sATPissynthesizedbymembraneboundorganellescalled
A)
ribosomes
B)
mitochondria
C)
lysosomes
D)
nucleoli
29. Theroughendoplasmicreticulumfunctionsin
A)
transport,respiration,andsynthesis
B)
contraction,transport,anddiffusion
C)
synthesis,storage,andtransport
D)
storage,transport,anddigestion
30. Whichorganellemodifies,packages,andsortsproteinsforsecretionorusewithinthecell?
A)
Golgiapparatus
B)
lysosome
endoplasmicreticulum
C)
D)
nucleus
31. Themostorganizedlevelofgeneticmaterial,visiblewithalightmicroscopeonlyduringcelldivision,is
the
A)
histone
B)
chromatin
ChapterTest:04CellCycleandDNAReplicationPage3of6


32.

33.

34.

35.

36.

37.

38.

39.

40.

41.

42.

C)
chromosome
D)
nucleosome
Nucleolimakewhichofthefollowing?
A)
smoothandroughendoplasmicreticulum
B)
ribosomalRNAandproteins
C)
histonesandDNA
D)
alloftheabove
Whichphaseofasomaticcell'slifecycleisthelongest?
A)
prophase
B)
anaphase
C)
metaphase
D)
interphase
Thecorrectsequenceofthestagesofmitosisis
A)
metaphase,anaphase,telophase,prophase
B)
prophase,anaphase,metaphase,telophase
C)
telophase,metaphase,anaphase,prophase
D)
prophase,metaphase,anaphase,telophase
Duringwhichstageofmitosisdoeschromatincoilintochromosomes?
A)
metaphase
B)
telophase
C)
prophase
D)
anaphase
ThetwocopiesofDNAinduplicatedchromosomesareconnectedataconstrictedregioncalledthe
A)
doublehelix
B)
centromere
C)
centrosome
D)
histone
____________occurswhenthechromosomeslineupattheequatorialplateofthecell.
A)
prophase
B)
metaphase
C)
anaphase
D)
telophase
Sisterchromatidspullaparttoformsinglestrandedchromosomesduring
A)
anaphase
B)
telophase
C)
prophase
D)
metaphase
Thecompletionof____________markstheendofcelldivision.
A)
telophase
B)
cytokinesis
C)
interphase
D)
anaphase
AccordingtoChargaff'srule,thefollowingproportionexistsinDNA.
A)
C=G
B)
CT
C)
CG
D)
C=T
TheactualsynthesisofDNAinE.coliisthefunctionof
A)
polymeraseI
B)
primase
C)
polymeraseIII
D)
DNAligase
AllofthefollowingwereoutcomesofAvery'sexperimenton"theactiveprinciple"except
A)
thearrayoftheelementsofpurifiedprincipleagreedcloselywithDNAandtheprinciple
centrifugedtothesamelevelasDNA.
ChapterTest:04CellCycleandDNAReplicationPage4of6

43.

44.

45.

46.

47.

48.

49.

50.

B)
proteindigestingenzymesdidnotaffectthesample
C)
theextractionoflipidsandproteinsfromtheprincipleonlyslightlyreduceditsactivity
D)
DNAdigestingenzyme,DNase,destroyedalltranscriptionactivity.
PolymeraseIIIisactuallyacomplexcontaining
A)
catalyticsubunits
B)
proofreadingsubunits
C)
"slidingclamp"subunits
D)
Alloftheabove
Byconvention,thesequenceofbasesinanucleicacidisusuallyexpressedinthe_________direction.
A)
3'to1'
B)
3'to5'
C)
1'to3'
D)
5'to3'
Since the first nucleotides cannot be linked in a newly synthesized strand in DNA replication,
___________isrequired.
A)
aDNAprimer
B)
DNApolymerase
C)
helicase
D)
anRNAprimer
InRNA,the2freehydroxylgroupisattachedtothe_______________carbonofthesugar.
A)
5'
B)
4'
C)
3'
D)
None
Asingleenzymeisspecifiedbyasingle
A)
chromosome
B)
gene
C)
nucleotide
D)
nucleosome
DNAreplicationiscalledsemiconservativebecause_______________oftheoriginalduplexappearsin
theduplexformedinreplication.
A)
none
B)
most
C)
half
D)
hardlyany
Eachunitofanucleicacidconsistingofasugar,attachedphosphategroup,andbaseisa
A)
nucleolus
B)
nucleotide
C)
nucleosome
D)
histone
InreplicationofDNA,anormalhelixisopenedanduntwistedby
A)
gyrase
B)
ligase
C)
deoxase
D)
helicase

ChapterTest:04CellCycleandDNAReplicationPage5of6

AnswertotheM.Sc.entranceclassChapterobjectiveTest04

Q.No.

OPTION
No.

Q.No.

OPTION
No.

26

27

28

29

30

31

32

33

34

10

35

11

36

12

37

13

38

14

39

15

40

16

41

17

42

18

43

19

44

20

45

21

46

22

47

23

48

24

49

25

50

Name:
_____________________________________
_____________________________________

Marks:

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