Multiple true false ( Past year compilation )

GMT 101 - Cell and Tissue

1. Regarding stratified squamous epithelium
A. present at dorsum of tongue.
B. at upper esophagus is keratinized.
C. zonula adherens is present at the sides.
D. desmosomes are present at basal lamina.
E. acquire its nutrient through diffusion.
2. Regarding nucleotide metabolism
A. Nucleotide consists of sugar and bases
B. De novo synthesis occurs in the liver and to a
limited extent in the brain.
C. Purine ring built on ribose-5-phosphate donated
by 5-phosphoribosyl-1-pyrophosphate
D. Degradation of uracil produces Xanthine
E. Xanthine oxidized to uric acid by Xanthine
oxidase
3. Regarding the epithelium
A. It is avascular.
B. There are intercellular spaces between the cells.
C. The epithelium exhibits polarity.
D. There are specialized cell junctions on apical
domain of the cells
E. Most epithelial cells renew continuously by
mitosis.
4. The following is the characteristics of thick skin
A sebaceous gland.
B hair follicle.
C sweat gland.
D arrector pili muscle. (F)
E stratum lucidum layer.

5. Regarding transport of substances across cell

membrane
A. facilitated diffusion needs energy
B. glucose move against its concentration gradient via
Na+- glucose cotransport
C. droplet of fluid is transported by pinocytosis
D. Vitamin A is transported by simple diffusion
E. Na+ move into the cell via Na+K+ATPase pump
6.regarding to necrosis
A. it refers cell death in living cells
B. infarction caused by bacteria infection
C. necrosis in tuberculosis is one in caseous appearance
D. the cytoplasm of necrosis cell is more basophil
E. coagulative the typically occur in the brain
7. Regarding spermiogenesis
A.
B.
C.
D.
E.

Occurs in epididymis
DNA replication occurs
Undergo mitochondrial rearrangement
Need sertoli cells
Physical transformation occurs

8. Structures derived from neural crest includes

A. Anterior of pituitary gland
B. Arachnoid mater
C. Eye lens
D. Medulla of adrenal gland
E. Sebaceous gland
9. Regarding protein
A They are polyelectrolytes.

B
C
D
E

The tertiary structure is stabilised by peptide bond.

Collagen has modified amino acids.
The primary structure is destroyed by heat.
They contain L-amino acids.

10. Regarding connective tissue

A. Fluid matrix of connective tissue is thickened by
proteoglycans
B. Gelatin is hydrated form of collagen
C. Fibrillin provides scaffolding for deposition of elastin
D. Its major type of fiber is collagen
E. Reticular connective tissue provides supportive
framework for the spleen
14. Regarding the skin
A. The dermal ridge separates the dermis from
epidermis
B. The epidermis is derived from mesoderm
C. Stratum basale is part of the dermis
D. Merkel's cells function as mechanoreceptors
E. Part of the dermis is keratinized
15.
a.
b.
c.
d.
e.

Epidermis consists of

Keratinocytes
Fibroblasts
Merkels cells
Melanocytes
Langerhaans cells

16. Fertilization
a. restores diploid number of chromosomes
b. is preceded by capacitation of spermatozoa
c. occurs in the isthmus of the uterine tube

d. determines the sex of the embryo

e. involves the release of acrosomal enzymes
17. Osmosis
a. involves energy expenditure
b. requires a transport carrier
c. its pressure is determined by amount of particles per
unit volume
d. involve water molecules
e. is an example of symport
18. Derivatives of the mesoderm
A. sensory of eye, ear and nose
B. ovaries
C. kidneys
D. bone
E. liver
GMT 102- Molecular biology & pharmacology
1.- Classification of enzyme
A. Oxidoreductase remove or add hydrogen group
B. Transferase rearrange enzyme
C. Hydrolase breaking bond by adding water
D. Lyases remove group without using water
E. Ligases transfer group
2.
A
B
C
D

DNA replication
helicase unwinds DNA helix.
occurs during S phase.
unzipping the exposed sugar backbone.
occurs in 5 to 3 direction.

Okazaki fragments are joined by RNA primer.

3. Regarding drug administration

A
Oral medication is free from side effects.
B
Sublingual drug is placed under the tongue until
dissolved.
C
Intradermal injection is deeper than subcutaneous
injection.
4. Routes of administration that by pass first pass effect
A. Sublingual
B. Rectal
C. Topical
D. Oral
E. Transdermal
5. Factors that can influence absorption of drugs:
A. Excretion of bile
B. Lipophilicity of drugs
C. Blood flow to absorption site
D. Expression of P-glycoprotein
E. Renal Function
6. Factors affecting renal excretion of drug
A. Molecular weight of the drug
B. Protein binding of the drug
C. Urine pH
D. Renal blood flow T
E. Fat solubility of drug
GMT 103- First Aid and medical ethics
1. A nurse working in a hospital is responsible for

A.
B.
C.
D.
E.

Providing care to patient

Educating patient with wound care
Protecting the patients rights
Practising the 4 steps of the Nursing Process
Making therapeutic decisions

2. The importance of effective and good communication

includes
A. better physician-patient satisfaction
B. less appropriate medical decisions
C. better health outcomes
D. adherence to treatment plans
E. increased incidence of malpractice claims
3. First aid care for seizures patient
a. Put tongue depressor
b. Remove dangerous substances from the
patient
c. Restrain the patient during epilepsy
d. Immediately apply with electric defibrillator
e. Rescue breaths to prevent hypoxia
4. Regarding wound bleeding
A tachycardia is a sign and symptom
B direct pressure is the right first aid measure
C elevation of limb above heart level is helpful
D remove the embedded object
E patients clothing can be used as bandage
5. Features of airway obstruction
A cyanosis
B difficulty speaking
C noisy breathing
D flaring of nostrils

E anxiety
6. Regarding nose bleeding
A tilt head backward
B sniff off the clots
C pinch the bridge of nose
D apply the ice on the nose
E apply ointment on nostrils
7. Drowning
A removal of water from stomach is first aid measure
B asphyxia is common cause of death
C cardiac compression is contraindicated
D hypothermia may occur
E removal of victim to dry ground is important
8. Burning
A breaking the blister is a first aid measure
B it is advisable to apply antiseptic lotion
C burning of nasal hair is an indication to send
subject to the hospital
D third degree pain is painful
E 1% burning is equivalent to the area of 1 palm of
the hand
9. Regarding fresh wound care
A clean tap water is used for irrigation
B applying antibiotic ointment on deep wound is
recommended
C soak the wound in warm water
D tetanus immunization is important
E bandaging is to prevent infection
10. Regarding emergency telephone numbers

A
B
C
D
E

Call 994 for fire department

Call 112 for mobile phone
Prank call is a major problem
999 is reserved for police department
False call is penalized under law

11. A 50 year-old man is clutching both his hands around

his throat, you should
A send him to hospital immediately
B observe the colour of his lips and face
C back blow if he coughs
D immediately start compression if unconscious
E Heimlich maneuver is carried out if he cannot talk
12. Accident with a tooth avulsion
A ask patient to bite clean cloth firmly on the
bleeding gum
B Scrub avulsed tooth with soap
C Put the avulsed tooth in milk
D Put in ice bag
E Put in antiseptic solution
GMT 104- Microbiology, Immunology, Pathology
1. the characteristics of fungi are
A. heterotrophic organism
B. capable of producing antibody
C. eukaryotes
D. has no pigment
E. reproduce asexually
2. virus
A. can be killed in an autoclave
B. contains ribosome

C. has no rigid cell wall

D. contains RNA and DNA
E. inactivated by an antibiotic
3. Immunoglobulin has
A) 4 heavy chain
B) 2 light chain
c) Fc for antigen attachment
D) complement site at light chain
4. During phagocytosis
A) lymphocyte adhere to bacteria
B) granule combine with nucleus
C) Degranulation occur
D) Phagosit form after phagosome
5. Immunoglobulin that activate complement C1q
through Fc include
A) IgG
B) IgA
C) IgM
D) IgE
E) IgD
6. Antigen binding site of immunoglobulin form by
A) constant light chain region
B) variable light chain region
C) constant heavy chain region
D) constant heavy and light chain region
E) variable heavy and light chain region
7. thrombosis may be promoted by

A) Virshow triad
B) fibrinolysis
C) Short clotting time
D) long clotting time
E) Inhibition of platelet aggregation
9. The features associated with chronic inflammation:
A. increase in circulating Ig M complexes
B. mononuclear cell infiltration
C. presence of granulation tissues
D. formation of abscess
E. development of a sinus tract
10. features of malignant neoplasm include
A. metastasis
B. encapsulation
C. intracell nuclear cytoplasm ratio
D. expansive growth
E. increased metastatic figures
11. examples of benign neoplasm
A. papilloma
B. melanoma
C. leiomyoma
D. leukemia
E. adenoma
12. regarding metaplasia
A. it is reversible process
B. it occurs in the bronchi
C. it is precursor to malignancy

D. it causes enlargement of affected organ

E. it is associated with loss of normal cellular orientation
13. acute inflammation can be caused by
A. streptococcus pneumonia
B. mycobacterium tuberculosis
C. neisseria meningitis
D. mycobacterium leprae
E. borrelia vincentii
14. neoplasia is
A. a disturbance of growth
B. always fatal
C. characteristic by persistent abnormal and autonomous
proliferation of cells
D. synonymous with cancer
E. often reversible
15.
A. air outside not contain pathogen
B. ultraviolet can kill the microorganism
C. tuberculosis can spread from human to human and
animal to human
D. Vibrio cholera can produce spores
E. Actinomisit live in the land
16. acute inflammation
A. Serves to destroy the injurious agent
B. Is similar regardless of the causactive agent
C. Results in transudate
D. Typically shows lymphocytosis in blood

E. Is characterized by formation og granuloma

17. the pathogenic mechanisms involved in the formation
of edema include
A. Increases potassium retention
B. Lymphatic obstruction
C. Increase hydrostatic pressure
D. Decrease osmotic pressure of blood
E. Decrease blood oxygen level
18. steps involved in phagocytosis include
A. diapedesis
B. recognition
C. chemotaxis
D. engulfment
E. degradation
19. regarding acute inflammation
A. calor mean redness
B. its a specific response
C. associated with repair
D. a response of injured tissue against local injury
E. PG is one of the chemical mediators
20. Normal flora
A. Increases colonization of pathogens
B. Commensals are the largest colony of normal flora in
human body
C.Opportunists causes disease in immunocompromised
human

D. Type of organism depends on host nutrition

E. Skin flora causes wound infection

21)Staging of carcinogenesis is based on

A. size of primary tumour
B. tumor differentiation
C. degree of cytologic atypia
D. presence or abscence of distance metastases
E. number of mitosis
22)Hypersensitivity type
A. I is mediated by cytotoxic T cell
B. II is mediated by mast cell.
C. III is mediated by immune complexes
D. III is characterised by elevated serum IgE level.
E. IV involves antibody-dependent cellular cytolysis.
23)Live attenuated vaccine include
A. diaptheria vaccine
B. rota virus vaccine
C. BCG
D. Hepatitis B virus vaccine
E. oral polio virus
GMT 105- Respiratory system
1. Mediators produced during acute phase response in
asthma include
A. protease.

B. platelet activating factor.

C. prostaglandin E2.
D. histamine.
E. leukotriene D4.
2. Regarding red hepatisation.
A. Liver appears red and swelling.
B. Exudate contains red blood cell.
C. Dominant cells are macrophages.
D. Inflammation occurs at alveolar wall.
E. Fibrin is present in the exudates.
3. Immunological investigation of allergic asthma :
A.
B.
C.
D.
E.

Complement assay
Mast cell agglutination test
Skin prick test
Specific IgE quantitation
B cell binding assay

4. Carcinoid tumor of lung

A.
Neuroendocrine tumor
B.
Associated with p53 mutation
C.
Associated with smoking
D.
Tumor cells are pleomorphic
E.
Tumor cells are contain neurosecretory granules
5. Causes of hypoxemia include
A. Hypoventilation
B. carbon monoxide poisoning
C. cyanide poisoning
D. pulmonary edema

E. high altitude

6. Emphysema is associated with

A.
abnormal enlargement of the bronchi
B.
cigarette smoking
C.
decreased lung compliance
D.
copious sputum production
E.
alpha-antitrypsin deficiency
7.The right lung
A.
is grooved by the arch of the aorta
B.
is grooved by the azygos vein
C.
possesses a lingual
D.
has three bronchopulmonary segments in its
middle lobe
E.
possesses a transverse fissure

8. A bronchopulmonary segment is
A.
supplied by a first division bronchus
B.
the functional unit of the lung
C.
separated from adjacent bronchopulmonary
segment by connective tissue septa
D.
important clinically during thoracic surgery
E.
identified on an antero-posterior radiograph of the
thorax
9.Regarding the muscles of muscles of the larynx
A.
They are innervated by the tenth cranial nerve
B.
Thyroarytenoid lengthens the vocal folds

C.
Posterior cricoarytenoid is supplied by the recurrent
laryngeal nerve
D.
Lateral cricoarytenoid abducts the vocal cords
E.
Transverse arytenoid abducts the arytenoid
cartilage
10.Streptococcus pneumoniae
A.
is a diplococcus
B.
possesses a capsule
C.
is a beta-haemolytic streptococcus
D.
has at least 80 serotypes
E.
is the causative agent in the majority of bacterial
pneumonias
11.Regarding bronchogenic carcinoma
A.
Squamois cell carcinoma is associated with
cigarette smoking
B.
Small cell carcinoma is the commonest type
C.
Adenocarcinoma is more common in females
D.
Cytoplasmic mucin in present in adenocarcinoma
E.
The histological type of tumour affects the
prognosis
12.Bacterial pneumonia
A.
due to Streptococcus pneumoniae is hospital
acquired
B.
is similar to viral pneumonia in clinical presentation
C.
is best diagnosed by sputum culture
D.
due to gram negative bacilli is secondary to viral
upper
respiratory tract infections
E.
is acute in on set

13.Community acquired pneumonia

A.
in the elderly is due to Mycoplasma pneumoniae
B.
associated with contact with animals include
Legionnaires
disease
C.
is associated with fungal infections
D.
secondary to influenza is most commonly due to
Staphylococcus aureus
E.
in chronic bronchitis is due to Haemophilus
influenzae in the majority
14.In
A.
B.
C.

Pulmonory tuberculosis
caseating granuloma is characteristic
ghon focus is a secondary lesion
wheezing is the typical clinical presentation

D.
localised fibrotic lesions are more common in the
apex
E.
dissemination to other organs is more common in
patients with acquired immune deficiency syndrome
15.Regarding lung carcinomas
A.
Small cell carcinoma is the commonest type
B.
Squamous cell carcinoma produces mucin
C.
Small cell carcinoma has the best prognosis
D.
Adenocarcinoma is known to arise from scar areas
E.
Bronchial carcinoid arises from neuroendocrine
cells