Académique Documents
Professionnel Documents
Culture Documents
Mapping grid
Question Mark
Content
Outcome
Band
H6
23
9.2.2, column 3
H6, H7, H8
12
H6
12
H6
12
H4, H7, H8
23
H6, H9
12
H1, H4
34
H9
23
H9
12
10
H9
34
11
H6
12
12
H6
12
13
H6
12
14
H6
23
15
H6
23
16a
H7
34
16b
H6, H7
23
16c(i)
9.111.1(a)
H11
23
16c(ii)
H6
23
16d
H6
34
17a
34
17b
34
18
H6
34
19a
H6
23
19b
H6
34
19c
H6
23
19d
56
19e
H6
23
29
Question Mark
Content
Outcome
Band
20a
H9
34
20b(i)
H9, H14
34
20b(ii)
H9, H14
56
21a
H9, H14
34
21b
H9, H14
34
22a
23
22b
34
22c
56
23a
9.112.1 (c)
H12
23
23b
9.112.1 (d)
H12
12
24a
H6
12
24b
H6
23
24c
H6
12
25
H6, H16
34
26a
9.5.6, column 1
H6
56
26b
H6, H13
34
26c
H6
34
26d
H6, H13
23
26e(i)
H6
23
26e(ii)
H6
23
26e(iii)
H2
34
26f(i)
H6
23
26f(ii)
H6
23
26f(iii)
H6, H13
34
30
Question Mark
Content
Outcome
Band
26g
H1, H3, H4
34
27a
9.6.2, column 1
H1, H6, H3 H8
23
27b
23
27c(i)
27c(ii)
H1, H6, H5
23
27c(iii)
56
27d(i)
34
27d(ii)
H6, H9
34
27e
34
27f
H6
34
27g
H6
12
28a
H9
45
28b
H9, H14
34
28c
H9, H14
34
28d
H9, H14
56
28e
H10
34
28f
34
28g(i)
H9
12
28g(ii)
H9
12
29a
H10
12
29b(i)
34
29b(ii)
23
29b(iii)
34
29c
34
29d(i)
34
29d(ii)
45
29e
H10
34
31
23
Question Mark
Content
30a
30b
30c(i)
Outcome
Band
56
H6
23
30c(ii)
9.9.5, column 3
H6, H4
34
30d(i)
H6
34
30d(ii)
H6
34
30e(i)
9.9.7
H6
12
30e(ii)
H6
12
30e(iii)
H1, H2, H6
45
34
Marking Guidelines
The marking guidelines are flexible and markers can, using their professional expertise and
judgement, accept and incorporate other correct statements/responses into the marking
scheme.
Answers
Section I Part A
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
D
C
D
A
B
A
A
C
A
B
D
C
D
B
A
32
Marking guidelines
Section I Part B
Question 16(a)
1. Life can be found at extremes ranging from -40oC to +120oC but most are found in the
-2oC to +40oC range (give relevant examples).
2. For each individual species the range is even narrower (use a correct example).
Marking guidelines
Criteria
Marks
Question 16(b)
Marking guidelines
Criteria
Marks
Question 16(c)(i)
Marking guidelines
Criteria
Marks
Identifies at least two correct data sources. (Sources is plural, means two.)
Question 16(c)(ii)
1. As temperature increases from 10C the activity would increase.
2. Until at some point the activity would drop dramatically. This would occur around 50C.
Marking guidelines
Criteria
Marks
1
33
Question 16(d)
1. As temperature increases chemical reactions speed up as molecules move faster/collide at
a faster rate.
2. As temperature gets to a certain point the enzyme is denatured and ceases to function.
Marking guidelines
Criteria
Marks
Question 17(a)
Marking guidelines
Criteria
Marks
Includes each of the following: an outline of what the case study was about,
indication of what the environmental change was, how the species
investigated had changed.
34
Question 17(b)
Marking guidelines
Criteria
Marks
34
Question 18
Marking guidelines
Criteria
Marks
Question 19(a)
No marks for recognition of the diagram as a dissected kidney.
The internal regions involved in the excretion of waste products are the medulla and the
cortex. 1 mark each for the correct identification of the medulla and the cortex.
Question 19(b)
The kidney does more than just filter the blood. NO MARKS at all for this statement. It
plays a central role in homeostasis, forming and excreting urine while regulating water and
salt concentration in the blood. It maintains the precise balance between waste disposal and
the animals needs for water and salt.
Marking guidelines
Criteria
Marks
Includes:
forms/excretes urine
OR
regulates water
OR
regulates salt
35
Question 19(c)
Marking guidelines
Criteria
Marks
The answer must include the requirement of energy for active transport and
not for passive transport.
Question 19(d)
Points needed in the answer are:
the justification is an argument in support of hormone replacement therapy which
would be that the disease could be controlled;
people who cannot secrete aldosterone (Addisons disease) have certain symptoms
(which include severe abdominal pain, nausea/vomiting, fatigue/weakness, kidney
failure, high urine output with a resulting low blood volume and this can result in heart
failure);
clearly states the role of aldosterone;
a replacement hormone is used to treat this condition.
Marking guidelines
Criteria
Marks
Question 19(e)
1. The role of ADH (vasopressin) is to basically control the reabsorption of water in the
nephrons.
2. The hypothalamus detects fluid levels in the blood and causes the pituitary to release ADH.
ADH works by increasing the permeability of the collecting ducts to water, thus allowing
more water to be absorbed from the urine into the blood.
3. The resulting urine is more concentrated.
Marking guidelines
Criteria
Marks
36
Question 20(a)
A gene is a section of DNA coding for proteins that expresses itself as the phenotype of
an organism. Alleles are alternative forms of a gene, e.g. the gene for height in peas has
2 alleles: tall, T; and short, t.
Marking guidelines
Criteria
Marks
Question 20(b)(i)
Correct symbols must be a capital letter for the dominant allele and lower case for the
recessive allele. Because all of the F1 were yellow then that is the dominant allele.
The matching genotypes and phenotypes are:
Parents pure breeding yellow
pure breeding white
F1
yellow
YY
yy
Yy
Marking guidelines
Criteria
Marks
37
Question 20(b)(ii)
Result is ratio of 3 yellow to 1 white.
Marking guidelines
Criteria
Marks
Gives any part of the answer that may be correct: ratio; colours; or enough
of the working.
Question 21(a)
The trait is recessive because in generation II it is not expressed in the parents of the two girls
III 1 and III 2 but is expressed in the two girls.
Marking guidelines
Criteria
Marks
Correctly states the trait is recessive and gives correct reason as above.
38
Question 21(b)
Since neither parent expresses the trait then they must be heterozygous carriers for it. That
means that the chance of producing a homozygous individual from a monohybrid cross would
be 25%.
Marking guidelines
Criteria
Marks
Question 22(a)
Marking guidelines
Criteria
Marks
Question 22(b)
Identify the gene required. Restriction enzymes are used to cut DNA in specific places.
Ligases are used to repair and strengthen the DNA.
Polymerase chain reaction is used to produce many copies of the recombinant DNA formed
by the previous processes.
Once the recombinant DNA is produced there are processes used to insert the DNA into the
host species, such as bacteria, viruses, microinjection and gene guns.
Marking guidelines
Criteria
Marks
39
Question 22(c)
Ethical issues include the ability to produce transgenic species that may help feed people in
places where it is currently hard to grow food or carry genes to make medicines or pesticides;
these transgenic species may cause havoc if they escape free into ecosystems or the chemicals
they make may harm people.
Marking guidelines
Criteria
Marks
Includes (1) ethical issues for and (2) against, (3) an example of a
transgenic species and (4) a reason for its use.
Question 23(a)
Marking guidelines
Criteria
Marks
Identifies and justifies two correct safe work practices identified and
correctly justified. The safe work practices must also correctly match the
investigation performed
Question 23(b)
Marking guidelines
Criteria
Marks
Correctly names waste product (must also correctly match the investigation
performed) and the correct disposal method.
Question 24(a)
Marking guidelines
Criteria
Correctly matches the cause of the disease with the group it belongs to.
Marks
1
There is no mark awarded for the name of the infectious disease and a mark is not given for
(a) if it is not an infectious disease or if it is not named.
40
Question 24(b)
Marking guidelines
Criteria
Marks
The host response usually consists of the production of antibodies; however, the answer may
vary depending on the disease.
Question 24(c)
Marking guidelines
Criteria
Marks
The correct answer depends on the disease but must be fully correct.
Question 25
An outline of what a vaccination does: the vaccinations introduce antigens into the body.
B cells are activated to produce large amounts of antibodies and memory B cells that are
stored in the lymph system ready for a future attack by the particular pathogen.
Marking guidelines
Criteria
Marks
41
Section II
Question 26(a)
A justification must include reasons as to why the statement is correct.
Marking guidelines
Criteria
Marks
Question 26(b)
This does not have to be an artistic/realistic drawing, but a schematic representation.
However, the diagram must still be easily interpreted so that the labels that are applied can be
understood in terms of their positions.
Marking guidelines
Criteria
Marks
42
Question 26(c)
Structure:
Function:
the tympanic membrane stretches across the ear canal; thin, taut
membrane.
vibrates when sound waves reaches it and transfers mechanical energy
into the middle ear
Marks
Question 26(d)
Marking guidelines
Criteria
Marks
One mark for a fully correct answer no half marks, nothing less accepted.
Question 26(e)(i)
Marking guidelines
Criteria
Marks
Question 26(e)(ii)
Refraction of light occurs when: (1) light passes from one substance to another with different
densities and (2) if the path of the light is not at right angles to the interface of the substances.
Marking guidelines
Criteria
Marks
43
Question 26(e)(iii)
Marking guidelines
Criteria
Marks
Partial justification.
Poor justification.
Question 26(f)(i)
Marking guidelines
Criteria
Marks
Question 26(f)(ii)
A neurone will only fire when it reaches the threshold of reaction at which point there is an all
or nothing response where the neurone fires at maximum intensity. Unless the neurone is
excited enough to reach the threshold of reaction it will not fire.
Marking guidelines
Criteria
Marks
Question 26 (f)(iii)
Marking guidelines
Criteria
Marks
Diagram with correctly labelled axes and correctly drawn action potential.
Diagram with correctly labelled axes but partially correctly drawn action
potential
OR
Diagram with incorrectly labelled axes and correctly drawn action
potential.
44
Criteria
Marks
Diagram with incorrectly labelled axes and partially correctly drawn action
potential
OR
Diagram with correctly labelled axes but incorrectly drawn action potential.
Question 26(g)
Marking guidelines
Criteria
Marks
Question 27(a)
Biotechnology is to utilise micro-organisms for specific uses, and to use living organisms to
make or modify a product or to improve plants or animals.
Marking guidelines
Criteria
Marks
Question 27(b)
Over time people were controlling the genetic makeup of the plants and animals they were
breeding as they chose characteristics that they preferred, particularly after breeding for
certain characteristics over many generations.
Marking guidelines
Criteria
Marks
45
Question 27(c)(i)
Answer includes:
name of an industrial fermentation process
full description of an industrial fermentation process
name of the micro-organism used
products of the fermentation
Marking guidelines
Criteria
Marks
Includes two of: the name of an industrial fermentation process, the name
of the micro-organism used, and the products of the fermentation only,
OR
Partially describes an industrial fermentation process AND only one of the
other three points.
Includes one of: the name of an industrial fermentation process, the name
of the micro-organism used, and the products of the fermentation only.
Question 27(c)(ii)
Marking guidelines
Criteria
Marks
46
Question 27(c)(iii)
Marking guidelines
Criteria
Marks
Question 27(d)(i)
1 mark for each fully correct answer.
Question 27(d)(ii)
The flow chart must contain at least three correct steps, one mark for each correct step.
Marking guidelines
Criteria
Marks
Question 27(e)
Marking guidelines
Criteria
Marks
Explains fully, including at least two groups and their different views.
47
Question 27(f)
The answer must include an outline of transcription, translation and the polypeptide chains
forming a protein.
Marking guidelines
Criteria
Marks
Marks
Question 28(a)
Marking guidelines
Criteria
Marks
48
Criteria
Marks
Question 28(b)
To have type A blood Amanda could be AA or AO BUT because her mother is type B blood,
then Amanda could only be AO. To have type B blood her mother can be BB or BO BUT
because Amanda does not have a B gene then her mother must be BO so that Amanda
inherited the O gene from her mother. Her father must therefore have an A gene to pass on to
Amanda and could therefore be AA, AO or AB.
Marking guidelines
Criteria
Marks
Question 28(c)
The two genotypes will be RrGg and RrGg.
This is a dihybrid cross which always produces offspring in the ratio of 9 : 3 : 3 : 1. The
outcome of the cross will therefore be:
Nine red plants with red flowers and green pods
Three red plants with red flowers and yellow pods
Three white plants with red flowers and green pods
One white plant with red flowers and yellow pods
The name of this cross is a dihybrid cross.
Marking scheme:
1 mark for the genotypes of both parents.
1 mark for naming this a dihybrid cross.
1 mark for the correct ratio.
1 mark for correctly matching all phenotypes of F1 with ratio.
49
Marking guidelines
Criteria
Marks
Question 28(d)
Assuming that the two dominant genes, R and G, are linked on one chromosome and the two
recessive genes, r and g, are linked on the other chromosome, then the gametes produced by
each parent would be RG and rg. The resulting F1 would have the same ratio as for a
monohybrid cross: 3 red, green : 1 white, yellow, not the 9 : 3 : 3 : 1 ratio for a dihybrid cross
where the genes are not linked.
Marking guidelines
Criteria
Marks
Correct prediction
OR
Partial explanation.
50
Question 28(e)
Homologues regulate the development of an organism. Experiments have confirmed that the
homologue gene from an amphibian can regulate the corresponding gene in mammals. A
mammal homologue gene can regulate the corresponding gene in insects.
These homologue genes exist in many eukaryotic organisms, vertebrates and invertebrates as
well as some fungi and plants. Evidence from biochemistry and molecular biology shows that
all cells contain similar amino acids, nucleotides, sugars and fatty acids. Chemical processes
such as protein synthesis within cells are also similar.
Marking guidelines
Criteria
Marks
Question 28(f)
An assessment would require making a judgement of its value. The HGP has many potential
applications and benefits as well as limitations. There would need to be a discussion of these.
Marking guidelines
Criteria
Marks
51
Question 28(g)(i)
This is a germ line mutation (no mark for this) because the trait is inherited (one mark for
this).
Question 28(g)(ii)
Germ line mutations can be inherited as they are passed on to offspring via sperm or ova.
Somatic mutations are in body tissue cells and therefore cannot be inherited. Therefore only
germ line mutations can affect a species. Somatic mutations only affect an individual during
their lifetime.
Marking guidelines
Criteria
Marks
Question 29(a)
1 mark for each correct answer.
Question 29(b)(i)
Marks
52
Question 29(b)(ii)
Correct answer includes:
conflicting dates based on different technologies
poor fossil record
different interpretations of the same evidence
only hard parts rather than whole organism are studied
1 mark each for three difficulties correctly outlined.
Question 29(b)(iii)
Mitochondrial DNA (mtDNA) consists of a single circle of DNA. During fertilisation the
female egg cell provides the mitochondria for the new organism. This means that
mitochondrial DNA is always passed through the female line. By comparing the
mitochondrial DNA from living primates it is possible to evolutionarily separate them based
on a constant rate of mutation. So how different the mtDNA is, is an indication of how many
years have passed since the two organisms shared a common ancestor.
Marking guidelines
Criteria
Marks
Question 29(c)
Marking guidelines
Criteria
Marks
53
Question 29(d)(i)
Answer needs to include the following.
Humans migrated throughout the world in small groups.
They would have become isolated by barriers, and genetic variations and mutations
within these groups were therefore not shared with other groups.
Genetic variations within each group that increased their chances of surviving and
reproducing would become more common in that group.
Natural selection would have led to differences between groups as they were exposed to
different environmental conditions causing regional differences.
Marking guidelines
Criteria
Marks
Question 29(d)(ii)
For example, body stature in humans shows polymorphism as there is a range of heights (1
mark). In hot equatorial areas a tall thin body stature has a larger surface area to volume ratio
for greater heat loss. A short stocky body is found in groups such as the Inuits (Eskimos) who
live in cold polar regions. This body shape has a smaller surface area to volume ratio which
allows better heat retention. These traits allow each body type to survive better in its
environment.
Marking guidelines
Criteria
Marks
54
Question 29(e)
Marking guidelines
Criteria
Marks
Outlines the Out of Africa model and gives one piece of evidence in
support of the theory.
Question 30(a)
Marking guidelines
Criteria
Marks
55
Question 30(b)
Igen-Housz showed that green plants purified air only when they were placed in light. This
demonstrated the need for light by plants and their effect upon air.
Marking guidelines
Criteria
Marks
Outlines as above.
Question 30(c)(i)
The two statements required are:
Isotope X would be suitable for use in plant growth experiments because of its short halflife.
Substances with short half-life can be used in biochemistry as the time that the substance is
in the organism will not affect its functioning.
Marking guidelines
Criteria
Marks
Question 30(c)(ii)
Marking guidelines
Criteria
Marks
56
Criteria
Marks
Question 30(d)(i)
The diagram should be well drawn and fully recognisable with the following labels:
the thylakoid membrane and lumen or space, the grana, the stroma, the inner and outer
chloroplast membrane, lamellae joining different grana throughout the stroma.
Marking guidelines
Criteria
Marks
Drawn and fully recognisable diagram, two or three of the labels as listed
above
OR
Drawn and mostly recognisable diagram, most of the labels as listed above.
Drawn and fully recognisable diagram, one of the labels as listed above
OR
Drawn and mostly recognisable diagram, some of the labels as listed above.
57
Question 30(d)(ii)
Marking guidelines
Criteria
Marks
Identifies and explains locations of the sites of light absorption and the site
of the Calvin cycle.
Location of the sites of light absorption and the site of the Calvin cycle
identified BUT only one explained
OR
Location of the sites of light absorption and the site of the Calvin cycle
only explained NOT correctly located.
Identifies and explains either the location of the sites of light absorption OR
the site of the Calvin cycle
OR
Identifies either the location of the sites of light absorption OR the site of
the Calvin cycle
OR
Explains one of the sites.
Question 30(e)(i)
Marking guidelines
Criteria
Marks
Question 30(e)(ii)
The energy used by cells is stored in the bonds between the second and third phosphate
groups in ATP. The hydrolysis (splitting) of ATP to ADP and Pi releases energy as in the
equation ATP ADP + Pi.
Marking guidelines
Criteria
Marks
The correct answer would be a circle drawn around the second and third
phosphate groups.
58
Question 30(e)(iii)
Marking guidelines
Criteria
Marks
59