Course Code: GBE 206

Level: Undergraduate

Course Title: MOLECULAR BIOLOGY II

Year: II

Semester: IV

Status: Mandatory

ECTS Credits: 5

COURSE DESCRIPTION

The course covers advanced topics on molecules, energy, and biosynthesis,

macromolecules (structure, shape, and information), how cells are studied, protein
function, basic genetic mechanisms, recombinant DNA technology, and control of gene
expression, etc.

COURSE OBJECTIVES

Students will move beyond their introductory textbooks towards a deeper understanding of
modern molecular biology.

COURSECONTENTS

Chromatin structure and function

Molecular mechanisms of DNA replication, mutability and repair of DNA
RNA polymerase dynamics
Regulation of gene expression by different types of RNA
Homologous recombination
Site specific recombination and transposition of DNA
Molecular mechanisms of transcription, RNA splicing
Molecular mechanisms of translation, the genetic code
Gene regulation in prokaryotes
Gene regulation in eukaryotes
Gene regulation during development
Genomics and Systems Biology
Techniques in Molecular Biology
Model Organisms
TEACHING/ASSESSMENT
Description

Teaching Methods

Interactive
Discussions and group works
Tutorials and Labs
Description (%)

Student Assessment Methods

Quizzes
Homework
Project
MidtermExamination
Final Examination
Lab

Learning Outcomes

Language of Instruction

(5%)
(10%)
20
40
25

Actively participate in courses and begin to take responsibility for learning.

Begin to work effectively as part of a team, developing interpersonal, organisational
and problem-solving skills with in a managed environment, exercising some personal
responsibility.
Present information in oral, written, and graphic forms in order to communicate
effectively with peers and tutors.

English

Textbook(s)

10%
10%
20%
20%
40%
25%

Alberts, B., Johnson, A, Lewis, J., Raff, M., Roberts, K., & Walter, P. (2007).
Molecular biology of the cell, 5th ed. New York: Garland Science.
Krebs, J.E, Goldstein, E.S., & Kilpatrick, K.S. (2011). Lewines Gene X. Jones and
Bartlett Publishers, Sudbury, MA.
Karp, G. (2013). Cell and Molecular Biology: Concepts and Experiments, 7th ed.
Hoboken: Wiley.

ECTS (ALLOCATED BASED ON STUDENT) WORKLOAD

Activities

Quanti
ty

Duration

Total Work Load

Lecture (14 weeks x Lecture hours per week)

14

28

Laboratory / Practice (14 weeks x Laboratory / Practice hours per week)

14

28

Midterm Examination (1 week)

Final Examination (1 week)

Preparation for Midterm Examination

14

14

Preparation for Final Examination

15

15

Assignment / Homework / Project

18

18

Seminar / Presentation

18

18

Total Workload
ECTS Credit (Total Workload / 25)

125
5