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__________1. This type of lipoproteins takes part in both triacylglycerol and cholesterol metabolism.

__________2. It is the predominant lipid in the chylomicrons and VLDL


__________3. The pigment responsible for the variation in color of normal fresh urine from light yellow to amber.
__________4. These lipoproteins are the vehicles of transport of triacylglycerol from the liver to the extrahepatic
tissue.
__________5. This hormone stimulates fatty acid synthesis
__________6. It comes from the putrefactive decomposition of tryptophan in the intestines
__________7. It inhibits HMG-CoA reductase activity.
__________8. It is laboratory method of separating the various lipoproteins in plasma.
__________9. What is the parent compound of ketone bodies.
__________10. How much cholesterol is eliminated from the body each day
__________11. It is the main storage of triacylglycerol in the body.
__________12. Bile acid found in largest amount in the bile itself.
__________13. What is the appearance of _____ when the lipoprotein abnormally in due to ___ beta __
__________14. It is the principal sterols in feces
__________15. What is the formula for ures

1.

Which of the following is not present in plasma proteins


a. Triacylglycerol
c.Phospholipids
b. Nicotinamide d. cholesteryl esters
2. Which of the following takes place in both triacylglycerol and cholesterol metabolism
a. LDL
c. VLDL
b. HDL
d. chylomicrons
3. In mna, cholesterol
a. Is converted to glycholic acid by intestinal bacteria
b. Is a part of cell membranes
c. C. can be metabolized mainly to acetyl CoA
d. Is precursor of squalene
4. Which of the following is the protein moiety of lipoproteins.
a. Cardiolipin
c. z-protein
b. Plasma lipoproteins d. apolipoproteins
5. Which of the following is a scavenger of esters-cholesterol not ___ by peripheral cells
a. HDL
c. IDL
b. LDL
d. chylomicrons
6. Which of the following is a precursor in the formation of LDL
a. VLD L
c. chylomicrons
b. LDL
d. IDL
7. Hyperlipoproteinemia is a disorder of metabolism in which.
a. Only one of the plasma lipoproteins is decreased
b. More than one of lipoproteins is decreased
c. One of the lipoproteins is increased
8. The main transport form of dietary triglyceride in the blood are lipoproteins formed in the intestines. These
are;
a. LDL
c. chylomicrons
b. HDL
d. VLDL
9. Which of the following in metabolically known to the most active of plasma lipid
a. Chylomicrons
c. free fattly acids
b. Triacylglycerols
d. HDL
10. Which of the following is the starting material for the synthesis of cholesterol

11.
12.

13.

14.
15.

16.

17.

18.
19.
20.
21.

22.
23.

a. Glucose
c. fatty acids
b. Acetyl CoA d.Triacylglycerols
Which of the following hormones stimulates fatty acid synthesis.
a. Epinephrine c. adrenalin
b. Glucagons
d. insulin
Which of the following provides the reducing power in the biosynthesis of cell components from oxidized
precursor
a. ATP
c. NADPH
b. Oxygen
d. energy
Serum cholesterol level maybe significantly changes by a diet with low ration of
a. Diglyceraldehydes to monoglycerides
b. Lactose to glucose
c. Vitamin K to vitamin D
d. Saturated to polyunsaturated fatty acids
In most mammals, which is the primary substance for fatty avid synthesis
a. Glucose
c. acetyl CoA
b. Pyruvate
d. glycerol
What happens to the density of lipoproteins as the proportion of lipid to protein increases
a. Its density increases
b. Its density is not affected
c. Its density decreases
Chylomicrons are derived from which of the following.
a. Intestinal absorption of triacyglycerol
b. Oxidation of triacylglycerol
c. Liver
d. Catabolism of VLDL
Which is the following lipoproteins has the highest electrophoresis mobility abd the lowest triglyceride
content.
a. VLDL
c. chylomicrons
b. LDL
d. catabolism of VLDL
Of the following compounds which one has the lowest density
a. Alpha lipoprotein
c. transferase
b. Beta lipoprotein
d. chylomicrons
All of the following are transport forms of lipids except one.
a. Chylomicrons
c. free cholesterol & cholesterol esters
b. VLDL
d. free fatty acids-albumins complex
Which of the following is/are the end products of cholesterol
a. Bile pigments
c. aldosterone
b. Caposterol d. bile acids
A lack of receptors for LDL will probably induce
a. Low of blood LDL
b. Low density of HMG-CoA
c. Decreased plasma cholesterol
d. Decreased endocytes
Which of the following is the major source of intracellular cholesterol in human
a. VLDL
c. HDL
b. LDL
d. albumin
What is the major role of fatty acid metabolism in promoting gluconeogenesis
a. It supplies atp
b. It reverses phosphoenol pyruvate carboxylase reductase
c. It activates AMP
d. All of the above

24. Which of the following is true of broen adipose tissue


a. It is a oresent in greater amounts in adults than in children
b. It characteristically operates near maximal metabolizing efficiency
c. It exhibits tightly coupled oxidative phosphorylation
d. It has a greater content of mitochondria than white adipose tissue
25. A lipoprotein in plasma that gives its milky appearance when excessive concentration
a. Chylomicrons
c. HDL
b. LDL
d. VLDL
26. Which of the following describes the free fatty acids of blood
a. They are metabolically inert
b. They are mainly bound to B-lipoprotein

27.
28.
29.

30.
31.

32.

33.

34.
35.

36.

c. They are stored in the fat depots


d. They are mainly bound to serum albumin
Which of the following is the major ___ human tissue
a. VLDL
c. HDL
b. LDL
d. chylomicrons
High concentration of the lipoproteins has __ relation to risk of CHD
a. VLDL
c. LDL
b. Chylomicrons
d. HDL
The following are true of cholesterol EXCEPT
a. Most abundant steroid in animal tissue
b. Precursor of endrogens, estrogens and adrenocortical hormone
c. Insoluble in water
d. Presents in lipoprotein of blood plasma
e. Fasting accelerates its biosynthesis
What type of lipoproteins results from excess B-lipoproteins
a. II-a
b. II-b
c. III
d. I
Intracellular synthesis of cholesterol can be blocked by inhibition of this enzyme which catalyzes the ratelimiting step
a. Methylmalonyl CoA mutas
b. Hydroxymethyl glutaryl coenzyme A reductase
c. Cholesterol esterase
d. Lecithin cholesterol acyl transferase
The following are true of fatty livers EXCEPT
a. Caused by a metabolic block in the production of plasma lipoproteins
b. Associated with raised levels of plasma free fatty acids
c. Mobilization of fat from adipose tissue
d. Due to hydrolysis of lipoproteins
Triacylglycerols of chylomicrons are
a. Intact triglycerides of intestinal lumen
b. Newly synthesized by intestinal cells
c. Transported from the liver
d. Converted to HDL
The de novo biosynthesis of triacylglycerols occurs mainly in the
a. Liver and brain
c. liver and adipose tissue
b. Liver and muscle
d. adipose tissue and muscle
Which of the following is true of cholesterol in human beings
a. It is converted to glycholic acid by intestinal bacteria
b. It is a part of cell membrane
c. It is a precursor of squalene
d. It can be metabolized mainly to acetyl CoA
Which of the following characterizes the role of lipoprotein lipase
a. It digest dietary lipoproteins in the intestinal lumen
b. It mobilizes dietary fat
c. It carries out intracellular lipolysis
d. It hydrolyzes triacylglycerols of plasma lipoproteins for transport of the released fatty acids into
tissues

37. Biosynthesis of cholesterol involves all of the following EXCEPT


a. Dimethylallyl pyropgosphate c. squalene
b. Succinyl Coa
38. Which of the following is the principal actions of insulin in adipose tissue
a. It increases the output of free fatty acids
b. It activates the hormone sensitive lipase
c. It inhibits the activity of the hormone
d. It has no effect on lipase activity
39. Which of the following substances controls lipolysis
a. ATP
c. methyl
b. ADP
d. cAMP
40. Mevalonate forms several active phosphorylated intermediators during the synthesis of cholesterol, which
of the following is the first intermediate formed by phosphorylation
a. mevalonate-2-pyrophosphate c. mevalonate-5-pyrophosphate
b. mevalonate-4-pyrophosphate d. squalene
41. which of the following causes turbidity of urine upon standing
a. urea only
c. peptide and ammonia
b. peptide and urea
d. nucleoproteins & epithelial cells
42. which of the following are the components of urochrome

43.
44.
45.
46.
47.
48.
49.
50.

a. magnesium and calcium


c. urea and peptide
b. urobilin and magnesium
d. urobilin and peptide
Urine on standings has amoniacal odor. This is caused by
a. Production of urea
c. hydrolysis of urea to ammonia
b. Presence of pathological conditions
d. Hydrolysis of peptide
Uric acid is one of the end products of purine metabolism. In man,
a. Cytosine
c. uracil
b. Thymine
d. adenine
Hippuric acid is a product of the reaction of which of the following
a. Benzoic acid and Glycine
c. glycine and urea
b. Benzoic acid and urea d. glycine and peptides
Which of the following is an abnormal constituents of urine
a. Ammonia
c. hippuric acid
b. Albumin
d. Urea
Which of the following is related to the percentage of solids in urine
a. Urine acidity and pH c. turbidity
b. Specific gravity
d. odor
Which of the following ions may be depleted as a result of excess ketone bodies
a. Na and Cl
c. Na and K
b. K and Cl
d. NH4 and Na
The presence of these substances in urine is indicative of extensive kidney damage
a. Albumins
c. glucose
b. Globulins
d. indican
Which of the following is present in greater amounts in the urine of herbivorous animals
a. Glycine
c. tryptophan
b. Bile
d. indican

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