Académique Documents
Professionnel Documents
Culture Documents
16. Amato S, Liu X, Zheng B, Cantley L, Rakic P, and Man HY. AMP-activated protein kinase
regulates neuronal polarization by interfering with PI 3-kinase localization. Science. 2011;
332:247-51.
17. Li Y, Xu S, Mihaylova MM, Zheng B, Hou X, Jiang B, Park O, Luo Z, Lefai E, Shyy JY,
Gao B, Wierzbicki M, Verbeuren TJ, Shaw RJ, Cohen RA, and Zang M. AMPK
phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis
in diet-induced insulin-resistant mice. Cell Metabolism. 2011; 13:376-88.
18. Tsou P, Zheng B, Hsu CH, Sasaki AT, and Cantley LC. A fluorescent reporter of AMPK
activity and cellular energy stress. Cell Metabolism. 2011; 13:476-86.
19. Mack HID, Zheng B, Asara J, and Thomas SM. AMPK-dependent phosphorylation of
ULK1 regulates ATG9 localization. Authophagy. 2012; 8(8):1197-1214
20. Yang Y, Wu J, Demir A, Castillo-Martin M, Melamed RD, Zhang G, Fukunaga-Kanabis M,
Perez-Lorenzo R, Zheng B, Silvers DN, Brunner G, Wang S, Rabadan R, Cordon-Cardo C,
Celebi JT. GAB2 induces tumor angiogenesis in NRAS-driven melanoma. Oncogene. doi:
2012; 10.1038/onc.2012.367.
21. Dagon Y, Hur E, Zheng B, Wellenstein K, Cantley LC, and Kahn BB. p70S6-kinase
phosphorylates AMPK on serine 491 to mediate leptins effect on food intake. Cell
Metabolism. 2012; 16(1):104-112.
22. Ning W, Zheng B, Shaywitz A, Dagon Y, Tower C, Bellinger G, Shen CH, Asara J, Kahn
B, Cantley JC. AMPK-dependent degradation of TXNIP in response to energy stress results
in enhanced glucose uptake via GLUT1. Molecular Cell 2013. 49:1167-75.
23. Che-Hung Shen, Ping Yuan, Rolando Perez-Lorenzo, Yaqing Zhang, Yang Ou, Sze Xian
Lee, John Asara, Lewis C. Cantley and Bin Zheng. AMPK phosphorylates BRAF to
regulate BRAF-KSR1 association and cell proliferation. Molecular Cell 2013. 52:161-172
24. Koichi Ito, Ping Yuan, Rolando Perez-Lorenzo, Christina Del Guzzo, Jung Hyun Lee, CheHung Shen, Marcus W. Bosenberg, Martin McMahon, Lewis C. Cantley, Bin Zheng.
Phenformin enhances the therapeutic benefit of BRAFV600E inhibition in melanoma. Proc.
Natl. Acad. Sci. USA. Oct 2013. www.pnas.org/cgi/
doi/10.1073/pnas.1317577110
25. Rolando Perez-Lorenzo, Kamraan Z Gill, Che-Hung Shen, Feng Xian Zhao, Bin Zheng,
Hans-Joachim Schulze, David N Silvers, Georg Brunner, Basil A Horst. 2013. A Tumor
Suppressor Function for the Lipid Phosphatase INPP4B in Melanocytic Neoplasms. J. Inv.
Derm. 11/2013; DOI:10.1038/jid.2013.511
Perez-Lorenzo R., and Zheng B. Targeted inhibition of BRAF kinase: opportunities and
challenges for therapeutics in melanoma. Bioscience Reports. 2012; 32:25-33.