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Notion of a Paradigm
Paradigm
Perspective or conceptual framework from within which a scientist
operates
We can never be totally objective; subjective factors interfere
No one paradigm sufficient to completely explain psychopathology
Genetics of Paradigm
Heredity plays a role in most behavior
Genes
Carriers of genetic information (DNA)
Impacted by environmental influences
e.g., stress, relationships, culture
Relationship between genes and environment is bidirectional
Nature via nurture
Important Genetic Terms
Gene expression
Proteins influence whether the action of a specific gene will occur
Polygenic transmission
Multiple gene pairs vs. single gene
Heritability
Extent to which variability in behavior is due to genetic factors
Polymorphism
Difference in DNA sequence on a gene occurring in a population
SNPs (Single Nucleotide Polymorphisms)
Identify differences in sequence of genes
CNVs (Copy Number Variations)
Identify differences in structure of genes; can be additions or deletions in
DNA within genes
Knockout studies
Removing specific genes in animals to observe effect on behavior