Wiley Lymphatic

Package Title: Testbank
Course Title: pap14

Chapter Number: 22
Question type: Multiple Choice
1) Which of the following is NOT a function of the lymphatic and immune system?
a) Draining excess interstitial fluid
b) Maintaining water homeostasis in the body
c) Transporting dietary lipids
d) Carrying out immune responses
Answer: b
Difficulty: Easy
Study Objective 1: SO 22.1 Understand the various components and major functions of the
lymphatic system.
Study Objective 2: SO 22.1.1 List the components and major functions of the lymphatic system.
Section Reference 1: Sec 22.1 Lymphatic System Structure and Function
2) What is the major difference between lymph and interstitial fluid?
a) Composition of electrolytes
b) White blood cells are present in lymph
c) Location
d) Types of proteins present
e) Red blood cells are present in interstitial fluid
Answer: c
Difficulty: Easy
lymphatic system.
Study Objective 2: SO 22.1.3 Explain the formation and flow of lymph.
3) Lack of resistance is also known as:
a) Pathogenic
b) Innate
c) Specific
d) Susceptibility
e) Lymphatic
Answer: d
Difficulty: Easy
lymphatic system.
Question type: Essay
4) Describe how lymphatic capillaries are one-way only vessels.
Answer:
Difficulty: Medium
lymphatic system.
Study Objective 2: SO 22.1.2 Describe the organization of lymphatic vessels.
Solution: The ends of the endothelial cells in the wall of the lymphatic capillary overlap. When
pressure is higher in the interstitial fluid than in the lymph, the cells separate slightly allowing
interstitial fluid into the vessel. When pressure is greater inside, the cells are tightly packed, not
allowing the lymph to cross back into the interstitial fluid.
5) What causes lymph from the small intestines to appear white?
a) Proteins
b) WBC
c) RBC
d) Lipids
e) Carbohydrates
Answer: d
Difficulty: Medium
lymphatic system.
6) Which of the following is not considered an organ of the immune system?
a) Spleen
b) Lymph node
c) Red bone marrow
d) Thymus
e) Pancreas
Answer: e
Difficulty: Easy
lymphatic system.
Study Objective 2: SO 22.1.4 Compare the structure and functions of the primary and secondary
lymphatic organs and tissues.
7) The left subclavian vein receives lymph from the
a) Left axillary vein
b) Lumbar trunk
c) Jugular trunk
d) Thoracic duct
e) Right lymphatic duct
Answer: d
Difficulty: Medium
lymphatic system.
8) The skeletal muscle and respiratory pumps are used in the
a) Lymphatic system
b) Cardiovascular system
c) Immune system
d) Lymphatic and Immune systems only
e) Lymphatic, Immune and Cardiovascular systems
Answer: e
Difficulty: Medium
lymphatic system.
9) Which organ produces a hormone that promotes maturation of T cells?
a) Spleen
b) Lymph node
c) Red bone marrow
d) Thymus
e) Pancreas
Answer: d
Difficulty: Easy
lymphatic system.
10) In which part of the thymus are T cells thought to die?
a) Capsule
b) Trabeculae
c) Epithelial cells
d) Thymic (Hassalls) corpuscles
e) T cells do not die in the thymus
Answer: d
Difficulty: Medium
lymphatic system.
11) Which of the following is a function of the lymphatic system?

a) Drain excessive interstitial fluid
b) Transport dietary lipids
c) Carry out immune responses
d) All of these are functions of the lymphatic system
e) None of these are functions of the lymphatic system
Answer: d
Difficulty: Easy
lymphatic system.
12) Which of the following is a function of the spleen?
a) Removes worn out blood cells
b) Circulates lymph
c) Cleanses interstitial fluid
d) Cleanses lymph
e) Traps microbes with mucus
Answer: a
Difficulty: Medium
lymphatic system.
13) Which of these does NOT provide a physical or chemical barrier?
a) Macrophages
b) Saliva
c) Urine
d) Mucus
e) Stratified squamous epithelium
Answer: a
Difficulty: Easy
Study Objective 1: SO 22.3 Describe the components of innate immunity.
Section Reference 1: Sec 22.3 Innate Immunity

14) Describe the barriers used in innate defense.
Answer:
Difficulty: Medium
Solution: Barriers used by the innate defense include epidermis, mucus, hairs, cilia, lacrimal
apparatus, saliva, urine, vaginal secretions, sebum, perspiration and gastric juices.
15) Which of these provides a non-specific cellular disease resistance mechanism?
a) Macrophages
b) T lymphocytes
c) B lymphocytes
d) Memory B cells
e) Stratified squamous epithelium
Answer: a
Difficulty: Easy
16) Which anti-microbial substances reduce viral replication (in uninfected cells)?
a) Transferrins
b) Perforins
c) Complement proteins
d) Defensins
e) Interferons
Answer: e
Difficulty: Medium

17) Which anti-microbial substances promote cytolysis, phagocytosis and inflammation?
a) Transferrins
b) Perforins
c) Complement proteins
d) Defensins
e) Interferons
Answer: c
Difficulty: Medium
18) Which of the following is NOT a sign of inflammation?
a) Redness
b) Pain
c) Heat
d) Mucus production
e) Swelling
Answer: d
Difficulty: Easy
19) Which of the following intensifies the effect of interferons and promotes the rate of repair?
a) Complement proteins
b) Perforin
c) Fever
d) Macrophages
e) Natural killer cells
Answer: c
Difficulty: Easy

20) Which chemical(s) do NOT induce vasodilation and permeability (increased fluid flow) to an
infection site?
a) Histamines
b) Kinins
c) Perforin
d) Leukotrienes
e) Complement
Answer: c
Difficulty: Medium
21) When B and T cells are fully developed and mature, they are described as being
a) Immunocompetent
b) Pluripotent stem cells
c) Primary lymphatic cells
d) Specifically promoted
e) Germ cells
Answer: a
Difficulty: Easy
Study Objective 1: SO 22.4 Understand the components and functions of adaptive (specific)
immunity and compare cell-mediated and antibody-mediated immunity.
Study Objective 2: SO 22.4.1 Define adaptive immunity, and describe how T cells and B cells
arise.
Section Reference 1: Sec 22.4 Adaptive Immunity
22) Which of the following induces the production of a specific antibody?
a) Phagocytosis
b) Antigen
c) Antibody
d) Defensin
e) Immunoglobulin
Answer: b
Difficulty: Easy
Study Objective 2: SO 22.4.2 Explain the relationship between an antigen and an antibody.
23) Which of the following stimulates an immune response ONLY when it is attached to a large
carrier molecule?
a) Epitope
b) Antigen
c) Hapten
d) MHC antigen
e) CD8
Answer: c
Difficulty: Easy
24) Genetic recombination generates diversity in what part (s) of the immune system?
a) Antigen receptors
b) MHC antigen
c) Hapten
d) MHC antigen and antigen receptors
e) Epitopes
Answer: d
Difficulty: Medium
25) Which class of cells includes macrophages, B cells and dendritic cells?
a) Antigen presenting cells
b) Primary lymphocytes
c) T cells
d) RBC
e) Epitope cells
Answer: a
Difficulty: Medium
26) To become activated, which of the following requires being bound to a foreign antigen AND
simultaneous costimulation?
a) B Cell
b) T Cell
c) Interferon
d) MHC antigen
e) Antigen presenting cell
Answer: b
Difficulty: Hard
Study Objective 1: SO 22.5 Understand the components and functions of the cell-mediated
immune response.
Study Objective 2: SO 22.5.1 Outline the steps in a cell-mediated immune response.
Section Reference 1: Sec 22.5 Cell-mediated Immunity
27) Which cells display CD4 proteins and interact with MHC Class II antigens?
a) Cytotoxic T cells
b) Helper T Cells
c) Memory T Cells
d) MHC antigens
e) B cells
Answer: b
Difficulty: Medium
immune response.

28) Which T cell toxin fragments DNA?
a) Perforin
b) Tumor antigen
c) Interferons
d) Lymphotoxin
e) Toxin T
Answer: d
Difficulty: Medium
immune response.
29) List the five actions of antibodies.
Answer:
Difficulty: Medium
Study Objective 1: SO 22.6 Understand the components and functions of the antibody-mediated
immune response.
Study Objective 2: SO 22.6.2 List the chemical characteristics and actions of antibodies.
Section Reference 1: Sec 22.6 Antibody-mediated Immunity
Solution: Antibodies can act as a neutralizing agent, they can immobilize bacteria, agglutinate
and precipitate the antigen, activate the complement and enhance phagocytosis.
30) Which class of antibodies is mainly found in sweat, tears, breast milk and GI secretions?
a) IgG
b) IgA
c) IgM
d) IgD
e) IgE
Answer: b
Difficulty: Medium
immune response.
Study Objective 2: SO 22.6.2 List the chemical characteristics and actions of antibodies.
31) Which of the following leads to inflammation, enhancement of phagocytosis and lysis of
microbes?
a) Classical complement system
b) Alternative complement system
c) Apoptosis
d) Classical and Alternative complement systems
e) Hapten activation
Answer: d
Difficulty: Medium
immune response.
Study Objective 2: SO 22.6.3 Explain how the complement system operates.
32) Which action makes microbes more susceptible to phagocytosis?
a) Opsonization
b) Cytolysis
c) Inflammation
d) Complement
e) Hybridoma
Answer: a
Difficulty: Easy
immune response.
Study Objective 2: SO 22.6.3 Explain how the complement system operates.
33) Which of the following is an inactive, self responsive cell?
a) Deleted cell
b) Hybridoma cell
c) Epitopic cell
d) Anergy cell
e) Natural killer cell
Answer: d
Difficulty: Medium
Study Objective 1: SO 22.7 Describe how self-recognition and self-tolerance develop.
Section Reference 1: Sec 22.7 Self-Recognition and Self-Tolerance
34) In the diagram, where do pluripotent stem cells come from?
a) A
b) B
c) C
d) D
e) None of these choices

Answer: b
Difficulty: Medium
lymphatic system.
35) In the diagram, where do T cells mature?
a) A
b) B
c) C
d) D
Answer: a
Difficulty: Easy
lymphatic system.
36) What does this diagram represent?
Answer:
Difficulty: Easy
lymphatic system.
Solution: The one-way flow of lymph through a lymph vessel.
37) In the diagram this vessel drains lymph from the upper right side of the body into venous
blood using a subclavian vein.
a) B
b) C
c) F
d) G
e) E
Answer: b
Difficulty: Medium
lymphatic system.
38) Which region includes B cells, follicular dendritic cells and macrophages?
a) B
b) C
c) D
d) E
e) F
Answer: b
Difficulty: Medium
lymphatic system.
39) In the diagram, which region includes B cells, plasma cells and macrophages?
a) B
b) C
c) D
d) E
Answer: c
Difficulty: Medium
lymphatic system.
40) Describe what is happening in the diagram.
Answer:
Difficulty: Easy
Study Objective 2: SO 22.4.3 Compare the functions of cell-mediated immunity and antibodymediated immunity.
Solution: The diagram represents processing and presenting of exogenous antigen by an antigenpresenting cell.
41) The inability of the immune system to protect the body from a pathogen causes
a) immunodeficiency diseases
b) allergy
c) autoimmune disease
d) transplantations
e) graft
Answer: a
Difficulty: Easy
Study Objective 1: SO 22.11 Describe the disorders of the lymphatic system.
Section Reference 1: Disorders: Homeostatic Imbalances that Affect the Lymphatic System and
Immunity
42) An acute allergic response can lead to:
a) transplantation
b) retroviruses
c) anaphylactic shock
d) passive immunity
e) active immunity
Answer: c
Difficulty: Medium
Immunity
43) Natural exposure to an infectious agent leads to:
a) Passive immunity
b) Active immunity
c) Both of these choices
d) None of these choices
Answer: b
Difficulty: Easy
immune response.
Study Objective 2: SO 22.6.4 Distinguish between a primary response and a secondary response
to infection.
44) Which class of antibodies indicates a recent invasion?
a) IgA
b) IgE
c) IgM
d) IgD
e) IgG
Answer: c
Difficulty: Medium
immune response.
to infection.
45) Which of the following cells is part of the bodys second line of defense?
a) Mucous cells
b) Germ cells
c) B and T Lymphocytes
d) Natural killer cells
Answer: d
Difficulty: Medium
46) Which of the following cells is the most variable cell in the immune system?
a) Natural killer cell
b) Monocyte
c) RBC
d) Lymphocyte
e) Macrophage
Answer: d
Difficulty: Hard
47) The primary response will peak how many days after an exposure?
a) 1 day or less
b) 27
c) 1017
d) 2030
e) Over a month
Answer: c
Difficulty: Medium
immune response.
to infection.
48) Which type of immunity defends against any type of invader?
a) Nonspecific
b) Specific
c) Cell mediated
d) Antibody mediated immunity
Answer: a
Difficulty: Easy
49) The ability of an antigen to react specifically with the antibodies or cells it has provoked is
called
a) Specificity
b) Immunogenicity
c) Reactivity
d) Epitopes
e) Immune Response
Answer: c
Difficulty: Medium
50) Which of the following is a small hormone that can stimulate or inhibit many normal cell
functions?
a) Enzyme
b) Kinins
c) Cytokine
d) MHC
e) Leukocyte
Answer: c
Difficulty: Medium
Study Objective 2: SO 22.4.3 Compare the functions of cell-mediated immunity and antibodymediated immunity.
51) Which structure in the figure is the main duct for the return of lymph to the blood?
a) A
b) F
c) G
d) C
e) H
Answer: a
Difficulty: Medium
lymphatic system.
52) Which structure in the figure is a lymphatic vessel?
a) B
b) C
c) D
d) J
e) G
Answer: e
Difficulty: Easy
lymphatic system.
53) Which structure in the figure is the cisterna chyli?
a) J
b) C
c) F
d) H
e) A
Answer: c
Difficulty: Easy
lymphatic system.
54) Which structure in the figure is the right lymphatic duct?
a) D
b) C
c) F
d) H
e) A
Answer: d
Difficulty: Easy
lymphatic system.
55) Lymph flowing from the afferent lymphatic vessel will travel next to which structure in the
figure?
a) A
b) B
c) C
d) D
e) E
Answer: b
Difficulty: Hard
lymphatic system.
56) Lymph travels to the efferent lymphatic vessel from which structure in the figure?
a) A
b) B
c) C
d) D
e) E
Answer: d
Difficulty: Hard
lymphatic system.
57) Lymph travels from the medullary sinus to which structure in the figure?
a) A
b) B
c) C
d) D
e) E
Answer: e
Difficulty: Hard
lymphatic system.
58) Lymph travels to the subcapsular sinus from which structure in the figure?
a) A
b) B
c) C
d) D
e) E
Answer: a
Difficulty: Hard
lymphatic system.
59) What type of cell is located in area B in the figure?
a) B cells
b) dendritic cells
c) macrophages
d) T cells
e) plasma cells
Answer: a
Difficulty: Hard
lymphatic system.
60) What types of cells are located in area C in the figure?
a) B cells and follicular dendritic cells

b) B cells and plasma cells
c) macrophages and B cells
d) T cells and dendritic cells
e) plasma cells and macrophages
Answer: d
Difficulty: Hard
lymphatic system.
61) Plasma cells are located in which area in the figure?
a) A
b) B
c) C
d) D
Answer: d
Difficulty: Hard
lymphatic system.
62) Which type of adaptive immunity will result from intravenous injection of
immunoglobulins?
a) naturally acquired active immunity
b) naturally acquired passive immunity
c) artificially acquired active immunity
d) artificially acquired passive immunity

Answer: d
Difficulty: Hard
immune response.
to infection.
63) Which type of adaptive immunity will result from mother-to-baby IgA transfer via breast
feeding?
a) naturally acquired active immunity
b) naturally acquired passive immunity
c) artificially acquired active immunity
d) artificially acquired passive immunity
Answer: b
Difficulty: Hard
immune response.
to infection.
64) Natural passive immunity is associated with which of the following?
a) Vaccination
b) Exposure to a microbe resulting in antibody formation
c) Receiving booster shots
d) Transfer of IgG from mother to fetus
e) Intravenous injection of antibodies
Answer: d
Difficulty: Medium
immune response.
to infection.
65) Which cells increase the permeability of blood vessels by releasing histamine?
a) neutrophils
b) eosinophils
c) lymphocytes
d) mast cells
e) macrophages
Answer: d
Difficulty: Medium
66) Which cytokine released by macrophages acts on the hypothalamus to raise the body
temperature during fever?
a) Interleukin-1
b) Interleukin-2
c) Interleukin-4
d) Gamma interferon
e) Perforin
Answer: a
Difficulty: Hard
67) Antigens that induce an allergic reaction are called
a) lymphotoxin
b) perforin
c) granulysin
d) interleukin-1
e) allergen
Answer: e
Difficulty: Easy
Immunity
68) Which cell is considered to be the most important cell in the immune system?
a) Cytotoxic T Cells
b) B lymphocytes
c) T Helper cells
d) Eosinophils
e) macrophages
Answer: c
Difficulty: Hard
immune response.
Study Objective 2: SO 22.5.2 Distinguish between the action of natural killer cells and cytotoxic
T cells.
69) Which of the following is NOT an effect of aging on the immune system?
a) Increased susceptibility to infections
b) Increased susceptibility to malignancies
c) Decreased response to vaccines
d) Increased response of T cells to antigens
e) Decreased production of antibodies
Answer: d
Difficulty: Easy
Study Objective 1: SO 22.9 Describe the effects of aging on the immune system.
Section Reference 1: Sec 22.9 Aging and the Immune System
70) Which of the following is an effect of stress on the immune system?
a) Increased activity of T lymphocytes
b) Increased activity of B lymphocytes
c) Activation of the immune system
d) Inhibition of the immune system

e) Increased production of antibodies
Answer: d
Difficulty: Easy
Study Objective 1: SO 22.8 Describe the effects of stress on immunity.
Section Reference 1: Sec 22.8 Stress and Immunity
71) Which cells of the immune system are the primary targets the HIV virus?
a) B cells
b) helper T cells
c) cytotoxic T cells
d) antigen-presenting cells
e) all of these cells are affected by HIV
Answer: b
Difficulty: Medium
Immunity
72) Which type of allergic reaction is the most common type?
a) Type I (anaphylactic) reaction
b) Type II (cytotoxic ) reaction
c) Type III (immune-complex) reactions
d) Type IV (cell-mediated) reactions
e) All of these types are common allergic reactions.
Answer: a
Difficulty: Medium
Immunity.
73) Which of the following organ systems is NOT aided by the MALT (mucosa-associated
lymphatic tissue)?
a) Respiratory system
b) Digestive system
c) Muscular system
d) Urinary system
e) Reproductive system
Answer: c
Difficulty: Medium
Study Objective 1: SO 22.10 Describe how the lymphatic system contributes to homeostasis.
Section Reference 1: Focus on Homeostasis: The Lymphatic System and Immunity
74) Which of the following is an incorrect matching of immune system cells and their functions?
a) Macrophage process and presentation of foreign antigens to T cells
b) Dendritic cell processes and presents antigen to T and B cells
c) B cells process and presents antigen to helper T cells
d) Plasma cell produces and secretes antibodies
e) All of these are correct matching of the cells and their functions
Answer: e
Difficulty: Medium
Study Objective 1: SO 22.7 Describe how self-recognition and self-tolerance develop.
Section Reference 1: Sec 22.7 Self-Recognition and Self-Tolerance
Question Type: Essay
75) Describe the ways to acquire adaptive immunity.
Difficulty: Medium
immune response.
to infection.
Answer: Naturally acquired active immunity is acquired following exposure to a microbe,
antigen recognition by B and T cells and costimulation leading to formation of antibodysecreting plasma cells, cytotoxic T cells, and B and T memory cells. Naturally acquired passive
immunity occurs when IgG antibodies are transferred from mother to fetus across the placental
barrier or IgA antibodies are transferred from mother to infant during breast-feeding. Artificially
acquired active immunity is acquired via antigens introduced during vaccinations. Artificially
acquired passive immunity is acquired via intravenous injection of immunoglobulins.

Wiley Lymphatic

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Wiley Lymphatic

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Package Title: Testbank

Course Title: pap14

11) Which of the following is a function of the lymphatic system?

Section Reference 1: Sec 22.3 Innate Immunity

Study Objective 1: SO 22.3 Describe the components of innate immunity.

Section Reference 1: Sec 22.3 Innate Immunity

Section Reference 1: Sec 22.5 Cell-mediated Immunity

e) None of these choices

40) Describe what is happening in the diagram.

59) What type of cell is located in area B in the figure?

60) What types of cells are located in area C in the figure?

a) B cells and follicular dendritic cells

61) Plasma cells are located in which area in the figure?

d) artificially acquired passive immunity

d) Inhibition of the immune system

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