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Diaphyseal Femur Fractures

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Diaphyseal Femur Fractures


Author: Bart Eastwood, DO; Chief Editor: Carlos J Lavernia, MD, FAAOS more...
Updated: Oct 2, 2013

Background
Orthopedic surgeons often encounter diaphyseal femur fractures.[1, 2, 3] Because these fractures most often result
from high-energy trauma, one must have a high index of suspension for complications or other injuries. While the
mainstay of treatment has been reamed interlocking intramedullary nailing, a variety of treatment options exist for
solitary fractures or fractures with associated injury.

Anteroposterior radiograph of a femur fracture in a 45-year-old man.

Lateral radiograph of a femur shaft fracture in a 45-year-old man.

Adult nonsurgical treatment options include skin traction, skeletal traction, cast brace, and casting. Nonsurgical
options are used infrequently outside of the younger pediatric population. Children have the same options, as well
as spica casting for those patients weighing less than 80 lb.[4, 5, 6]
Surgical options in adults include the mainstays of intramedullary nailing, either antegrade or retrograde. Plate
fixation and external fixation are used less frequently, but these have a place in the decision-making process for
the ideal treatment in certain cases. Pediatric cases may also use flexible rods in addition to the adult options
mentioned. However, one must consider the patient's immature bones, open physes, parental care available, and
growth potential when forming a treatment plan in children.[4, 5, 6, 7]

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Anteroposterior radiograph of the hip and proximal femur after antegrade intramedullary (IM) nail placement.

Lateral radiograph of the distal femur after antegrade intramedullary (IM) nail placement.

History of the Procedure


Prior to the 1900s, diaphyseal femur fractures were treated with various types of splinting. However, with the
discovery of skeletal radiology near the end of the 19th century came an understanding of the forces acting on
fractured bones and a change in the treatment of such injuries. In 1907 and 1909, Steinmann and Kirschner
respectively developed the first traction treatment modalities with the use of pins or wires under tension.[8]
Early attempts at internal fixation of such fractures achieved little success until Kntscher developed and utilized
the intramedullary nail in 1937. After a short period of disagreement, the nailing method began to spread during
World War II in Europe and later in North America. Intramedullary nailing became prominent in the United States
in the 1970s. Since the intramedullary nailing technique was introduced in 1939, it has continued to evolve into the
antegrade reamed interlocking nails that are the standard today.

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Problem
Femoral-shaft fractures are usually easy to treat compared with the high-energy injuries associated with the
fracture, in which complications tend to occur. Severetolife-threatening injuries often occur along with the
femoral-shaft fracture. Death, fat embolism,deep venous thrombosis (DVT),pulmonary embolism, pneumonia
development, multiorgan failure, long intensive care unit (ICU) stays, infection, hemorrhage, nerve palsies, rare
compartment syndrome, nonunion, delayed union, and malunion may also occur as complications of a diaphyseal
femur fracture.

Epidemiology
Frequency
Fractures of the femoral shaft are among the more common fractures that an orthopedist sees.[9] Injury is most
common among persons younger than 25 years and those older than 65 years. Analysis of a statewide discharge
database revealed an incidence of 1.33 fractures per 10,000 people. The number of shaft fractures in the elderly is
increasing secondary to the greater number of geriatric patients in the general population.
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Etiology
Femoral-shaft fractures are usually the result of trauma.[10, 11] Motor vehicle accidents, pedestrian-versus-vehicle
accidents, falls, and gunshot wounds are among the most common causes. Pathologic fractures in adults are
most often the result of osteoporosis and metastatic disease. In children, it is also important to consider abuse
and underlying neuromuscular disorders and metabolic bone disease as causes of the fracture. Stress fractures
also may develop in the femur shaft, often associated with an increase in physical activity. Low-energy shaft
fractures have also been associated with the prolonged use of bisphosphonate drugs for treating osteoporosis.[12]

Pathophysiology
Fractures are most often due to a bending load applied to the femur with comminution occurring via higher
magnitude forces. Torsional loads, in contrast, form a spiral fracture pattern.

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Presentation
The usual history of diaphyseal femur fractures is that of trauma.[13] If the history does not consist of trauma, one
should suspect a pathologic bone condition. Clinically, the injury is most often apparent. Pain, swelling,
shortening, and deformity are usually present in the region.
Because of the high association of other injuries, the advanced trauma life support (ATLS) protocol should be
followed. As always, a neurovascular assessment should be completed, though this type of injury is rare with
femoral-shaft fractures. Examination of the pelvis and hip is of great importance to investigate possible fracture or
dislocation. A thorough examination of the knee also should be completed to detect any ligamentous or bony
injury.

Indications
Currently, surgery is indicated for most femur fractures because of the high rate of union, low rate of
complications, and the advantage of early fracture stabilization, which decreases the morbidity and mortality rates
in patients (especially polytrauma patients) with these fractures.
Definite indications include polytrauma patients, especially those with head and chest injuries, and those with
injuries to multiple limbs or those otherwise unable to care for themselves to maximize postoperative
independence. Most others are surgical candidates because of the lower incidence of complication and the higher
union rates with surgery. Those who should not be treated surgically include patients too unstable to tolerate the
procedure and children under 80 lb.

Relevant Anatomy
The femur is one of the largest and strongest bones in the human body. The femur can be divided into regions
consisting of the head, neck, intertrochanteric, subtrochanteric (extending 5 cm distal to the lesser trochanter),
shaft, supracondylar, and condylar regions.
The structures of the thigh also can be divided into compartments. Within the anterior compartment lies the
quadriceps femoris, sartorius, psoas, iliacus, pectineus, as well as the femoral artery, vein, and nerve, along with
the lateral femoral cutaneous nerve. The medial compartment holds the gracilis, adductor brevis and longus,
adductor magnus, obturator externus, profunda femoris artery and vein, and the obturator artery, vein, and nerve.
Finally, the posterior compartment holds the semitendinosus, the semimembranosus, the biceps femoris, portions
of the adductor magnus, perforating branches of the profunda femoris artery, the sciatic nerve, and posterior
femoral cutaneous nerve.
The metaphyseal area begins proximally with the subtrochanteric region and distally with the supracondylar region
with the diaphysis in between. Lying posterior on the femur is the linea aspera, which provides a major attachment
for fascia. The femur is not perfectly straight; it has a noted anterior bow. The degree of the bow varies from person
to person, but explains the need for curved nails in order to hold the reduction.
The femur has an abundant vascular supply, receiving the bulk of the blood from the profunda femoral artery.[14] A
nutrient artery usually enters along the linea aspera posteriorly and proximally on the femur and supplies the
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endosteal circulation. The endosteal circulation supplies the inner two thirds to three fourths of the cortex, making
the normal blood flow centrifugal in direction. The periosteal circulation enters posteriorly for the most part along
the linea aspera.
The periosteal circulation is almost entirely directed in a circumferential direction, having little or no longitudinal
spread. Therefore, small wires may be placed around the femur without the danger of devascularizing an area, but
large bands should be avoided. Periosteal circulation has been estimated to serve only the outer one fourth of the
cortex. However, the periosteal circulation is critical to fracture healing in the diaphysis.
When a fracture is displaced, the medullary vessels are disrupted and the periosteal vessels predominate as the
vascular supply to the fracture site during early healing. In response to fracture, the periosteal vessels proliferate,
while the endosteal circulation is restored much later. Therefore, the use of slotted nails may allow for enhanced
return of endosteal neovascularization and a more normal blood flow pattern. The significance of periosteal blood
flow in healing also emphasizes the importance of avoiding periosteal stripping especially along the linea aspera.
Depending on the level of the fracture and the insertion and attachment of the different muscles of the thigh, varied
deformities result. The proximal segment of the femur is under a valgus force of abduction by the gluteus minimus,
medius, and maximus. The short external rotators also exert a force on the proximal segment of fractures. A
component of flexion and external rotation also exists due to the attachment of the iliopsoas on the less
trochanter.
The adductors span most of the medial femur and produce an axial and varus force on the femur. Some of these
medial forces are countered by the tension band effect of the fascia lata. The distal femur is under a flexing
influence by the gastrocnemius.

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Contraindications
Surgery for diaphyseal femur fracture should be reserved for those able to tolerate the appropriate procedure for
their circumstance. Young children can often be treated successfully with noninvasive measures; thus, surgery
can be avoided.

Contributor Information and Disclosures


Author
Bart Eastwood, DO Orthopedic Surgeon, Regional Orthopedics, Spearfish, SD
Bart Eastwood, DO is a member of the following medical societies: American Academy of Orthopaedic
Surgeons, American Osteopathic Academy of Orthopedics, and American Osteopathic Association
Disclosure: Nothing to disclose.
Coauthor(s)
Thomas Knutson, DO Consulting Surgeon, Department of Orthopedic Surgery, Center for Orthopedic
Excellence
Disclosure: Nothing to disclose.
Specialty Editor Board
Steven I Rabin, MD Clinical Associate Professor, Department of Orthopedic Surgery and Rehabilitation,
Loyola University, Chicago Stritch School of Medicine; Chairman, Department of Orthopedic Surgery and
Musculoskeletal Medicine, Dreyer Medical Clinic; Chairman, Department of Surgery, Provena Mercy Medical
Center
Steven I Rabin, MD is a member of the following medical societies: American Academy of Orthopaedic
Surgeons, American Fracture Association, AO Foundation, and Orthopaedic Trauma Association
Disclosure: Nothing to disclose.
Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center
College of Pharmacy; Editor-in-Chief, Medscape Drug Reference
Disclosure: Medscape Salary Employment
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B Sonny Bal, MD, JD, MBA Associate Professor, Department of Orthopedic Surgery, University of MissouriColumbia School of Medicine
B Sonny Bal, MD, JD, MBA is a member of the following medical societies: American Academy of Orthopaedic
Surgeons
Disclosure: Bonesmart.org None Online orthopaedic marketing and information portal; OrthoMind None Social
networking for orthopaedic surgeons; Amedica Corporation Stock options and compensation Manufacturer of
Orthopaedic Implants; BalBrenner LLC Ownership interest Consulting; Zimmer Royalty Consulting; Medtronic
None Consulting; ConforMIS Consulting
Dinesh Patel, MD, FACS Associate Clinical Professor of Orthopedic Surgery, Harvard Medical School; Chief
of Arthroscopic Surgery, Department of Orthopedic Surgery, Massachusetts General Hospital
Dinesh Patel, MD, FACS is a member of the following medical societies: American Academy of Orthopaedic
Surgeons
Disclosure: Nothing to disclose.
Chief Editor
Carlos J Lavernia, MD, FAAOS Adjunct Clinical Professor, Department of Orthopedic Surgery, University of
Miami School of Medicine; Medical Director, Orthopedic Institute at Mercy Hospital
Carlos J Lavernia, MD, FAAOS is a member of the following medical societies: American Academy of
Orthopaedic Surgeons, American Association of Hip and Knee Surgeons, Arthritis Foundation, Biomedical
Engineering Society, Florida Orthopaedic Society, and Orthopaedic Research Society
Disclosure: Zimmer Stock Implant Designer
Additional Contributors
The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous author
coauthor Dr H Kurtis Biggs to the development and writing of this article.

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