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Presentation
Late phase reactions can occur 4-6 hours after the initial reaction and can be as
severe as or worse than the original reaction.
Patients should be given a prescription for at least 2 autoinjectable epinephrine
doses (eg, 2 EpiPens ) and instructed in their proper use. Instruct Patients to carry
them at all times or to keep one at home and one in their purse or at work.
Patients should be informed of the potential for future anaphylactic reactions, and
what medications to use when to call 911 or go to the nearest emergency
department (even if feeling better after the epinephrine).