GNIPST BULLETIN 2015

01-05-2015

1st May, 2015

Volume No.: 44 Issue No.: 04

Vision

TO REACH THE PINNACLE OF GLORY AS A CENTRE OF EXCELLENCE IN THE

FIELD OF PHARMACEUTICAL AND BIOLOGICAL SCIENCES BY KNOWLEDGE
BASED LEARNING AND PRACTICE

Contents

Message from PRINCIPAL

Editorial board
Historical article
News Update
Knowledge based Article
Disease Related Breaking
News
Upcoming Events
Drugs Update
Campus News
Students Section
Editors Note
Archive

GNIPST Photo Gallery

For your comments/contribution

OR For Back-Issues,
mailto:gnipstbulletin@gmail.com
GURU NANAK INSTITUTE OF PHARMACEUTICAL
SCIENCE AND TECHNOLOGY
Website: http://gnipst.ac.in

01-05-2015

MESSAGE FROM PRINCIPAL

"It can happen. It does happen.

But it can't happen if you quit." Lauren Dane.

We are what we repeatedly do.

Excellence then is not an act, but a habit. Aristotle

It gives me immense pleasure to pen a few words for our e-bulletin. At the onset I would like to thank the
last years editors and congratulate the newly selected editors for the current year.
Our first consideration is always in the best interest of the students. Our goal is to promote academic
excellence and continuous improvement.
I believe that excellence in education is aided by creating a learning environment in which all learners are
supported in maximizing their potential and talents. Education needs to focus on personalized learning
and instruction, while promoting an education system that is impartial, universally accessible, and meeting
the needs of all students.
It is of paramount importance that our learners have sufficient motivation and encouragement in order to
achieve their aims. We are all very proud of you, our students, and your accomplishments and look
forward to watching as you put your mark on the profession in the years ahead.
The call of the time is to progress, not merely to move ahead. Our progressive Management is looking
forward and wants our Institute to flourish as a Post Graduate Institute of Excellence. Steps are taken in
this direction and fruits of these efforts will be received by our students in the near future. Our Teachers
are committed and dedicated for the development of the institution by imparting their knowledge and play
the role of facilitator as well as role model to our students.
The Pharmacy profession is thriving with a multitude of possibilities, opportunities and positive
challenges. At Guru Nanak Institute of Pharmaceutical Science and Technology, our focus is on holistic
needs of our students.
I am confident that the students of GNIPST will recognize all the possibilities, take full advantage of the
opportunities and meet the challenges with purpose and determination.
Excellence in Education is not a final destination, it is a continuous walk. I welcome you to join us on
this path.
My best wishes to all.
Dr. A. Sengupta

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01-05-2015

EDITORIAL BOARD
CHIEF EDITOR
EDITOR
ASSOCIATE EDITOR

DR. ABHIJIT SENGUPTA

MS. JEENATARA BEGUM
MR. DIPANJAN MANDAL

HISTORICAL ARTICLE

Stanislas Limousin Pharmacal Inventor:

One of those men singularly gifted in combining scientific

knowledge with technical skill and with inventive genius was the
french retail pharmacist, Stanislas Limousin (1831-1887). Among
the many devices which he introduced to Pharmacy and Medicine
were the medicine dropper; the system of coloring poisons (such as
corrosive sublimate); and wafer cachets (which found favor prior
to mass production of the gelatin capsule). His greatest
contributions, however, were the development and perfection of
apparatus for the inhalation and therapeutic administration of
oxygen; and invention of glass ampoules that could be sealed and
sterilized for preservation of solutions for hypodermic use.

NEWS UPDATE

New potential melanoma drug target discovered:

(01st May, 2015)
A new treatment for melanoma could be on the horizon, thanks to
a recent finding. In the study, authors report that they found high
levels of an enzyme in melanoma samples that they believe is a
potential drug target.

Practical gel simply 'clicks'

applications: (01st May, 2015)

for

biomedical

A novel, truly biocompatible alginate hydrogel has been developed

that can be synthesized using 'click chemistry' towards better
delivery of drugs, growth factors and living cells for biomedical
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01-05-2015

applications. The gel is formed using chemical crosslinking

strategies that allow engineers to entrap cells or molecules inside
the gel without damaging them or rendering them inactive,
scientists report.

Researchers create DNA repair map of the

entire human genome: (01st May, 2015)
When common chemotherapy drugs damage DNA in cancer cells,
the cells cant replicate. But the cells do have ways to repair the
DNA and the cancer drugs arent effective to do so. Researchers
have developed a way to find where this DNA repair happens.
Their goal is to increase the potency of cancer drugs.

Genome library, blood test aim to minimize

statin side effects, maximize benefits: (01st
May, 2015)
In the midst of the growing and often conflicting data around the
benefits of statins, researchers are developing gene-based resources
to help improve statin efficacy and cost-effectiveness and to reduce
the incidence of adverse effects -- some of which can be fatal.

Link between inherited genetic variations,

outcomes of non-small cell lung cancer patients

discovered: (01st May, 2015)
Non-small cell lung cancer (NSCLC) is the most common type of
lung cancer. Patients diagnosed with NSCLC have a poor
prognosis, with a 5-year survival rate of only 16 percent.
Researchers hope to improve NSCLC patient survival with the
results of a study that found that inherited genetic variations in
interleukin genes are associated with improved patient survival
and response to therapy.

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01-05-2015

Lifetime intense physical activity may lower risk

for non-Hodgkin lymphoma: (01st May, 2015)
Performing vigorous physical activity over one's lifetime may lower
risk for non-Hodgkin lymphoma. Because not much is known
about what causes non-Hodgkin lymphoma, identifying risk
factors is particularly important for the prevention and control of
this cancer, the main researcher noted.

Many young ACL surgery patients need second

surgery later on: (01st May, 2015)
Orthopedic surgeons are seeing an epidemic of anterior cruciate
ligament injuries among young athletes, and a large number of
patients who have surgery to reconstruct a torn ACL undergo a
second knee operation later on, according to a study.

Prolonged statin use may lower risk of lung

cancer death

: (01st May, 2015)

Lung cancer patients who used statins in the year prior to a lung
cancer diagnosis or after a lung cancer diagnosis had a reduction in
the risk of death from the disease, researchers report at the
conclusion of a recent study.

Frequent aspirin use reduces risk of cervical

cancer by nearly half: (30th April, 2015)
Long-term and frequent use of aspirin is associated with
significantly decreased risk of cervical cancer, according to a study.
According to the American Cancer Society, 12,900 new cases of
cervical cancer will be diagnosed and 4,100 women will die from
the disease in 2015.
For detail mail to editor

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01-05-2015

KNOWLEDGE BASED ARTICLE

Light -- not pain-killing drugs -- used to activate

brain's opioid receptors
Despite the abuse potential of opioid drugs, they have long been
the best option for patients suffering from severe pain. The drugs
interact with receptors on brain cells to tamp down the body's
pain response. But now, neuroscientists at Washington University
School of Medicine in St. Louis have found a way to activate opioid
receptors with light.
In a test tube, the scientists melded the light-sensing protein
rhodopsin to key parts of opioid receptors to activate receptor
pathways using light. They also influenced the behavior of mice by
injecting the receptors into the brain, using light instead of drugs
to stimulate a reward response.
Their findings are published online April 30 in the journal Neuron.
The eventual hope is to develop ways to use light to relieve pain, a
line of discovery that also could lead to better pain-killing drugs
with fewer side effects.
"It's conceivable that with much more research we could develop
ways to use light to relieve pain without a patient needing to take
a pain-killing drug with side effects," said first author Edward R.
Siuda, a graduate student in the laboratory of Michael R. Bruchas,
PhD, an assistant professor of anesthesiology and of neurobiology.
But before that's possible, the researchers are attempting to learn
the most effective ways to activate and deactivate the opioid
receptor's pathways in brain cells. Bruchas, the study's principal
investigator, explained that working with light rather than painkilling drugs makes it much easier to understand how the
receptors function within the complex array of cells and circuits in
the brain and spinal cord.
"It's been difficult to determine exactly how opioid receptors work
because they have multiple functions in the body," Bruchas
explained. "These receptors interact with pain-killing drugs called
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01-05-2015

opiates, but they also are involved in breathing, are found in the
gastrointestinal tract and play a role in the reward response."
So the researchers sought a way to limit opioid receptors to
performing a single task at a time, and it turned out to be almost as
easy as flipping on a light switch, according to Bruchas, Siuda and
their collaborators, including co-first author Bryan A. Copits, PhD,
a postdoctoral research scholar in the laboratory of Robert W.
Gereau, IV, PhD, the Dr. Seymour and Rose T. Brown Professor of
Anesthesiology.
By combining the rhodopsin protein, which senses light in the
eye's retina, with a specific type of opioid receptor called a Mu
opioid receptor, the researchers were able to build a receptor that
responds to light in exactly the same way that standard opioid
receptors respond to pain-killing drugs.
When an opioid receptor is exposed to a pain-killing drug, it
initiates activity in specific chemical pathways in the brain and
spinal cord. And when the researchers shone light on the receptors
that contained rhodopsin, the same cellular pathways were
activated.
In a test tube and in cells, Siuda exposed the receptors to light and
then watched as they released the same chemicals that standard
opioid receptors release. Then, in mice, the researchers implanted a
light-emitting diode (LED) device the size of a human hair into a
brain region linked to the reward response. They injected the lightsensing receptors they had genetically manufactured into the same
brain region. Neurons in that part of the brain release chemicals
such as dopamine that create feelings of euphoria.
In decades of past opioid studies, researchers have observed mice
and rats to press a lever to receive a dose of morphine, for example.
The morphine would activate opioid receptors and the release of
dopamine, and the animals would enjoy the response and press the
lever again to continue feeling that reward sensation. This is one of
the reasons opiates are so often abused in patients being treated
for pain -- people like the way the drugs make them feel as much as
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01-05-2015

the pain relief they provide -- and rates of abuse have skyrocketed
over the past ten years.
Working to deliver a similar reward sensation using light, the
researchers put the mice into an enclosed chamber. In one part of
the chamber, the lighted laser fiber-optic device stimulated the
release of dopamine in the brain. When the animals left that part of
the chamber, the light in the brain turned off. Soon after, the mice
returned to the part of the chamber that activated the fiber-optic
device so that the brain could receive more light stimulation.
"By activating the receptors with light, we are presumably causing
the brain to release more dopamine," Bruchas explained. "Rather
than a drug such as morphine activating an opioid receptor, the
light provides the reward."
The researchers were able to vary the animals' response depending
on the amount and type of light emitted by the LED. Different
colors of light, longer and shorter exposure to light, and whether
the light pulsed or was constant all produced slightly different
effects.
When a person takes an opioid drug such as Vicodin or
OxyContin to relieve pain, such drugs interact with receptors in
the brain to blunt pain sensations. But over time, patients develop
tolerance and sometimes addiction. Opioids also can dramatically
slow a person's breathing, too, and typically cause constipation.
In theory, receptors tuned to light may not present the same
danger. Siuda said it someday may be possible to activate, or
deactivate, nerve cells without affecting any of the other receptors
that pain-killing drugs trigger, although achieving that goal will be
difficult.
Bruchas' team is planning future studies that will use these
receptors to test ways to control the brain cells that mediate pain
and reward behavior with light rather than drugs.
Jeenatara Begum
Assistant Professor
GNIPST
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01-05-2015

DISEASE RELATED BREAKING NEWS

Meningococcal
2015)

disease

Niger:

(29th

April,

Between 1 January and 25 April 2015, the Ministry of Public Health

of Niger notified WHO of 1543 suspected cases of meningococcal
disease, including 147 deaths. Suspected cases have been reported
in seven of Nigers eight regions. Meningococcal meningitis
outbreaks have been confirmed in several areas of Dosso and
Niamey regions.
Read more

UPCOMING EVENTS

61st IPSF World Congress sponsored by Indian Pharmaceutical

Association (IPA) at Marriott Hotel, Hyderabad, India is going to
on 30th July to 9th August, 2015.

DRUGS UPDATES

FDA Approves Kybella (deoxycholic acid) to

Treat Submental Fullness, or 'Double Chin':
(29th April, 2015)
The
U.S.
Food
and
Drug
Administration
approved Kybella (deoxycholic acid), a treatment for adults with
moderate-to-severe fat below the chin, known as submental fat.
Using Kybella for the treatment of fat outside of the submental
area is not approved and is not recommended.
Read more

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01-05-2015

CAMPUS NEWS
SPIRIT JIS 2015
On 03 to 05th April, 2015 JIS organised SPIRIT JIS 2015.
GPAT 2015 Result:
The following B.Pharm. final year students have qualified, GPAT2015. We congratulate them all.
Diksha Kumari
Rupanjay Bhattacharya
Avik Paul
Xtasy 2015:
GNIPST is going to organize the Tech Fest Xtasy 2015 from 30th
March, 2015 to 1st April, 2015.
FINISHING SCHOOL TRAINING PROGRAMME:
The FINISHING SCHOOL TRAINING PROGRAMME is going to
organize by the Entrepreneurship Development Cell and Training
& Placement Cell, GNIPST in collaboration with Indian Pharmacy
Graduates Association (IPGA), Bengal Branch from 21st February
to 11th April, 2015 at GNIPST Auditorium.
On 21st February, 2015 the Finishing School Training Programme of
GNIPST was inaugurated by Sri Soumen Mukhopadhyay, Deputy
Director, Drug Control Office, Goutam Kr. Sen, President, IPGA,
Mr. Subroto Saha, Asst. Directorate, Drug Control Office, Mr.
Ranendra Chakraborty, Sales Manager and Associate Director Dr.
Reddys Laboratory.
On 28th February, 2015 Dr. D. Roy, Former Deputy Drug
Controller, Mr. Sujoy Chakraborty, divisional Therapy Manager,
Cipla and Mr. Vikranjit Biswas, Senior Manager, Learning &
Development, Cipla delivered their valuable lectures in the 2nd day
FINISHING SCHOOL TRAINING PROGRAMME of GNIPST.
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01-05-2015

On 14th March, 2015 Mr. Milindra Bhattacharya, Senior Manager,

QA & QC, Emami Ltd. and Mr. Joydev Bhoumik, Manager,
Operation, Ranbaxy Laboratory Limited delivered their valuable
lectures in the 3rd day FINISHING SCHOOL TRAINING
PROGRAMME of GNIPST.
On 21st March, 2015 Mr. Tridib Neogi, Associate Vice-President
(Quality Assurance), Albert David Ltd. delivered his valuable
lectures in the 4th FINISHING SCHOOL TRAINING
PROGRAMME of GNIPST.
On 28th March, 2015 Dr. Gautam Chaterjee, an Alumni of Jadavpur
University and presently associated with NIPER delivered his
valuable lectures in the 5th FINISHING SCHOOL TRAINING
PROGRAMME of GNIPST.
On 11th April, 2015 the closing ceremony of the FINISHING
SCHOOL TRAINING PROGRAMME was held in GNIPST
Auditorium.
JOBS:
All the students of Final Year B. Pharm and M. Pharm are hereby
informed that an interview will be conducted by GSK for sales and
marketing job.
Details given below:
Date
: 27.03.2015
Time
: 09:45 am
Venue : GSK Consumer Healthcare Limited, Unit No. 208,
2nd Floor, Ecospace Campus B (3 B), New Town,
Rajarhat, 24 Pgs (N). Kolkata-700156.

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THYROCARE provisionally selected 15 students from JIS Group.

Amongst these, 3 students of B. Sc (H) Biotechnology and M. Sc
Biotechnology have been selected.
Ipsita Mondal (M. Sc Biotechnology)
Debriti Paul (M. Sc Biotechnology)
Debopriya Chatterjee {B. Sc (H) Biotechnology}
The final year students of B.Pharm (31 students) and B.Sc (11
students) attended the pooled campus drive of Abbott India Ltd.
on 10th March, 2015 at Jadavpur University. Among them 17
students have gone through to the final round of this pooled
campus drive and short listed for final selection.

ACHIEVEMENT:

Congratulations to Anurag Chanda, student of B.Pharm final year

who have got the 1st prize in poster presentation event in Prakriti
2015 at Department of Agricultural and Food engineering, IIT,
Kharagpur.

OTHERS:
On 24th and 25th February, 2015 Swamiji of Gourio Math was
delivered some motivational lectuers in GNIPST.
th

The students of GNIPST participated in the 4 Sardar Jodh Singh

Trophy organised by NIT on 20th February, 2015.

On 8th February, 2015 Gnipst celebrated the Reunion programme
Reminiscence Reloaded 2015.
The 2nd Annual Sports of GNIPST was held on 28th and 29th
January,2015 in College campus ground.
Congratulations to all the winner of Annual Sports of GNIPST,
2015.
100 meter flat race (Girls):
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Priya Roy
Nirmita Gupta
Joyoti Ghosh
100 meter flat race (Boys):
Arijit Mitra Thakur
Deep Chakraborty Arindam Ganguly
Three legged race (Girls):
Nayana Sinha
Anjali Mondal
Saheli Mukherjee
Arjita Biswas
Aindrila Bhowmick Archita Basu
200 meter flat race (Girls):
Priya Roy
Nirmita Gupta
Anjali Mondal
Long Jump (Boys):
Dipankar Kamila
Arindam Ganguly
Rohan Datta
Skipping (Girls):
Saheli Mukherjee
Indira Saha
Jayita Roy
Shotput (Girls):
Chandrika Saha
Priya Roy
Sneha Paul
Shotput (Boys):
Arijit Mitra Thakur
Arindam Ganguly Rohan Datta
Musical Chair (Staff):
Mr. Abir Koley Ms. Priyanka Ray Mr. Debabrata Ghoshdastidar
Discuss Throw(Girls):
Priya Roy
Arjita Biswas
Varsha Shrivastava
50 meter female flat race (staff):
Ms. Aparupa Bhattacharya Ms. Priyanka Ray Ms. Anuranjita
Kundu
100 meter male flat race (staff):
Mr. Debabrata Ghoshdastidar Mr. Mrinal Datta
Walking race female (staff):
Ms. Aparupa Bhattacharya
Ms. Anuranjita Kundu
Ms. Sumana Roy
Balance race female (staff):
Ms. Aparupa Bhattacharya
Dr. Sriparna KunduSen
Ms. Priyanka Ray

Mr. Ranjit
Ghosh

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01-05-2015

Tug of war (Female staff):

Ms. Priyanka Ray
Ms. Aparupa Bhattacharya
Ms. Prathama SenGupta
Dr. Sriparna KunduSen
Ms. Sumana Roy
Tug of war (Male staff):
Mr. Debabrata Ghoshdastidar
Mr. Abir Koley
Sk. Ziaur Rahman
Mr. Ranjit Ghosh
Mr. Koushik Dhar
Balance race (Girls):
Indira Saha
Aindrila Bhowmick
Pamolita Paul
Long Jump (Girls):
Aindrila Bhowmick
Nirmita Gupta
Krishnakali Basu
200 meter flat race (Boys):
Dipankar Kamila
Arijit Mitra Thakur
Kaustav Sakar
Sack race (Girls):
Aindrila Bhowmick
Nirmita Gupta
Sayani Banerjee
Sack race (Boys):
Rohan Datta
Souvik Debnath
Sayantan Das
Relay race (Boys):
Dipankar Kamila
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01-05-2015

Arijit Mitra Thakur

Soumyajit Sinha
Sneham Sen
Relay race (Girls):
Joyoti Ghosh
Aindrila Bhowmick
Anjali Mondal
Poulami Sarkar
Go for Goal (Boys):
Abhijit Kumar Mondal
Arkajyoti Hazra
Abhinandan Mondal
Tug of war (Boys):
Dipu Roy
Vishal Singh
Sk Minhaz Uddin Ahmed
Ritobroto Paul
Rohan Dutta
Tug of war (Girls):
Krishnakali Basu
Indira Saha
Chandrika Saha
Maitryee Banerjee
Kajal Nagpal
The male faculties and staffs of GNIPST participated in the 4th
th
Sardar Jodh Singh Trophy organised by NIT on 15 January, 2015.
An industrial tour and biodiversity tour was conducted in Sikkim
for B.Pharm, B.Sc. and M.Sc. students under the supervision of Mr.
Dipanjan Mandal, Mr. Samrat Bose and Ms. Aparupa Bhattacharya
th
th
from 5 January to 12 January, 2015.
GNIPST commemorated the Birth Anniversary of Swami
th
Vivekananda on Monday, 12 January, 2015 & served Oldages and
Orphanages.
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01-05-2015

STUDENTS SECTION
WHO CAN ANS WER FIRS T????
Who is the author of The Seven
Ages of man?
Answer of Previous Issues Questions:
A) Sukumar sen

Identify the person

Answer of Previous Issues Image:

R.k.Laxman

Send
your
thoughts/
Quiz/Puzzles/games/write-ups or any other
contributions
for
Students
Section&
answers of this Section at gnipstbulletin@gmail.com

EDITORS NOTE
It is a great pleasure for me to publish the 4th issue of 44th Volume
of GNIPST BULLETIN. All the followers of GNIPST BULLETIN
are able to avail the bulletin through facebook account GNIPST
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01-05-2015

bulletin I am very much thankful to all the GNIPST members and

readers who are giving their valuable comments, encouragements
and supports. I am also thankful to Dr. Abhijit Sengupta, Director
of GNIPST for his valuable advice and encouragement. Special
thanks to Dr. Prerona Saha, Mr. Debabrata Ghosh Dastidar
and Mr. Soumya Bhattacharya for their kind co-operation and
technical supports. Thank you Mr. Soumya Bhattacharya for the
questionnaires of the student section. An important part of the
improvement of the bulletin is the contribution of the readers. You
are invited to send in your write ups, notes, critiques or any kind of
contribution for the forthcoming special and regular issue.
ARCHIVE

AICTE has sanctioned a release of grant under Research

Promotion Scheme (RPS) during the financial year 2012-13to
GNIPST as per the details below:
a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical
Science & Technology.
b. Principal Investigator: Dr. LopamudraDutta.
c. Grant-in-aid sanctioned:Rs. 16,25000/- only
d. Approved duration: 3 years
e. Title of the project: Screening and identification of potential
medicinal plant of Purulia & Bankura districts of West Bengal
with respect to diseases such as diabetes, rheumatism, Jaundice,
hypertension and developing biotechnological tools for enhancing
bioactive molecules in these plants.

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Activity Clubs of GNIPST:

Name of Club
SPORTS
LITERARY AND PAINTING
SCIENCE AND INNOVATIVE
MODELLING
ECO
SOCIAL SERVICES
PHOTOGRAPHY
CULTURAL
DEBATE AND EXTEMPORE

Member Faculty
Mr. Debabrata GhoshDastidar
Ms. Jeenatara Begum
Mr. Samrat Bose
Ms. Sumana Roy
Dr. Asis Bala
Ms. Sanchari Bhattacharya
Ms. Priyanka Ray
Mr. Soumya Bhattacharya

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