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PCB 3023 Quiz #4

1. Which of the following is the most complete list of processes occurring in the
nucleus of a cell?
a) transcription
b) replication
c) transcription and replication
d) replication, transcription and RNA splicing
e) replication, transcription, and translation
f) replication, transcription, RNA splicing, and translation
2. In addition to a polymerization domain, DNA polymerase has a domain that _____.
a) identifies incorrectly incorporated nucleotides and removes them
b) covalently joins Okazaki fragments
c) unwinds the DNA double helix
d) More than one of these answers is correct.
3. Which is a logical reason as to why DNA chains are built by adding nucleotides to
the 3' end rather than to the 5' end of the growing chain?
a) The 5' end of polynucleotides is unreactive.
b) It is energetically unfavorable to add nucleotides to the 5' end.
c) It would require more energy to add nucleotides to the 5' end.
d) If nucleotides were added to the 5' end proofreading could not occur.
e) If nucleotides were added to the 5' end an RNA primer would not work.
4. DNA mismatch repair occurs after _____.
a) replication
b) transcription
c) DNA damage called depurination
d) DNA damage called thymine dimers
5. Which of the following are reasons for making an RNA copy of a gene?
a) Making numerous copies allows for rapid protein production.
b) The decision to make RNA, then later destroy it is a basis for controlling
gene expression.
c) Differential processing of RNA transcripts allows for more than one protein
to be made from the same gene.
d) All of these answers apply.
6. Which of the following is a nucleic acid SEQUENCE that assists in the mechanics of
transcription?
a) promoter
b) terminator
c) coding region
d) start site
e) stop site
f) more than one of these answers
g) all of these answers

7. Making DNA and making RNA BOTH require a distinct _____ enzyme.
a) polymerase
b) primase
c) ligase
d) helicase
e) More than one of these answers is correct.
8. Which of the following apply to both REPLICATION and TRANSCRIPTION?
a) a polynucleotide is created in a 5 to 3 direction
b) a template strand is read in a 3 to 5 direction
c) energy to add a nucleotide is supplied by that nucleotide
d) Two of these answers are correct.
e) All of these answers are correct.
9. Which processes involve making phosphodiester bonds (which hold together
polynucleotides) and/or breaking them?
a) replication
b) transcription
c) RNA splicing
d) proofreading (during replication)
e) Some, but not all of these answers are correct.
f) All of these answers are correct.
10.Uracil-containing nucleotides may be utilized in the reaction catalyzed by which of
the following enzymes?
a) primase
b) RNA polymerase
c) DNA polymerase
d) Two of these answers are correct.
e) All of these answers are correct.