September 2013

Single Best Answer/Questions

1.

Cyrokine involved in ovarian hyperstimulation syndrome ?

Vegf , IL2, tnf ,

Ans
VEGF
2.

Pt came with rt illiac fossa pain , left adenexal mass , b hcg 850 ?
What ll b next step
A)Admit and repeat usg in next 24 hrs
B)Admit and repeat b hcg in next 24. Hrs
C)Admit and do urgent laparotomy
D)Call her next time in opd

Ans
Admit and repeat beta hCG after 48 hrs
3.

What about HIV pt with screening weakly positive

HIV Ag/Abx ratio =1.5
1 confirmatiry test negative
2 cimfirmatiry test specimen not adequate
Ur next step
Options
A)Counsell her that she may have admit her to GUM for further tests
B)Ask abt risk factors
C)Te her she has no disease

Ans
A
4.

Patient post date admitted for induction of labour with PG, ARM + oxytocin
Oxytocin given for 6 hrs
Then she developed hyponatraemia what is cause??

Ans
Excessive iv fluid
5.

There was a question about endometrial biopsy and sth about the look of the endometrium and
its stroma being very less or none at all..
options were:
1.luteal
2.follicular
3.atrophic
4.Secretory

Ans
3
6.

What abt AMH ?

A)Its androgenic
B)Produce from granulosa cells during reproductive period
C) apoptosis of Target tissue

Ans..
A
7.

Hystosalpingography
Some options
A) it can be done within the first 10 days of proliferative phase

B)It can exclude endometriosis

C)It cant detect uterine abnormalities

Ans
A
8.

Perinatal mortality rate ???formula?

Ans
still birth +death 1 week postnatal
9.

Sacro iliac joint is

A)synovial
B)Primary Cartiigenous
C)Secondry Cartiligenous

Ans..
A
10. BRCA 1 positive
Risk
A)- 50% breast cancer , 30% ovarian cancer
B)- 75 % breast +30% Ovarian
C)- 30 % breast + 10 % ovarian
??????other options

Ans
75% Breast, 30% Ovarian
11. there was a question on urine output...
A).0.25ml/kg/hr
B).0.5 mi/kg/hr
C).1ml/kg/hr
D).2ml/kg/hr
E).5ml/kg/hr

Ans
E
12. which vitamin would u give an alcoholic pregnant woman at ?32 wks
with obstetric cholestasis
A
B1
K
E
Ans
Vitamin K
13. Unwanted effect of pregnancy not related to physiological changes :
Backache
Dysuria
Constipation
Tiredness

Ans
Dysuria
14. Pregnant lady with severe itching
LFT normal
Serum bile acids elevated
Serum bilirubin normal
Whats te diagnosis?
A)- obstetric cholestasis
B)- pruritic urticarial plaques and papules of pregnancy
C)- normal

D)- ?
E)-?

Ans
A
Obstetric Cholestesis
15. Sign of incomplete miscarriage :
A)Os open
B)Os close

Ans
A
16. Hypoechoic area in uterus , bilateral adenxa clear , what was that
Endometrioma
Hydrosalpinx
Luteal cyst

Ans
Hydrosalpinx
17. U derdevelop mandible, which structure ll be damaged
A)Facial artery
B)Facial nerve
C)Trigeminal Nerve

Ans
Fascial Nerve
18. Varicella zoster any one remember it
IgG positive
Ig Mnegative
Interpretation?

Ans
Immune status
19. Rectus muscle supplied by which nerve below umblicus
A)Inferior epigastric
B)Inguinal Nerve

Ans
Inferior epigastric
20. Pregnant 24 wks with vulval soreness
+ve candida
+ ve B streptococci
What u will do ???
A) give fluconazole..
B)Fluconazole and Penicillin V
C)Dont give anything and tell her that she will get antibiotic at the time of delivery
D)Fluconazole and Amoxicillin
Ans
C?
21. Duplication of DNA occurs at which phase?
A)G2,
B) G1
C), S phase

Ans
C
22. Warfarin
A)Nasal hypoplasia
B)Agensis of corpus callosum

Ans
A
23. post delivery patient with DM, bronchial asthma dehydrated, apyrexia, vomiting
Rbs 4.5 mmol

Na 122 mmol/lit
Cause?
A)- Addison
B)- diabetic ketoacidosis

Ans
A
24. For i.m inj adrenaline diluted in
A)1in 10,
B)1 in 100,
c) 1000,10 000
d)1 in 1000

Ans
D
25. A pregnant woman plans to go to Middle East.What vaccination cant be given to her?
A)Tetanus
B).Diphtheria
C)BCG
D)Hepatitis A
E)Hepatitis B

Ans
C
26. First heart beat seen on usg :
A)Day 20,
B)Day 22,
C)Day 28
E)Day,32

Ans
B
27. Nerve supplying posterior 2/3 rd of vagina
Perineal nerve of S4
Posterior cut br of femoral nerve
Pudendal n
28. Letrzol inhibits which encyme?
a)21 hydroxylase
b) Aromatase inhibitor
29. Rate of bone loss /year if you give young women GnRH
Not remember if it correct Q
If any body remember correct it !!!!

1- increases by 5%
2- increases by 10%
3-decreases by 5%
4-decreases by 10 %
5- no change
30. Pt with history of pulmonary embolism , which is C/I
POPs
oCPs
Levonorgestrel
31. mercaptopurine is a metabolite of
1- azathioprine
2-cyclophosphamide
3-doxorubicine
4-vincristine

Ans
1
32. The thick white vaginal discharge
1- candida

33.
34.
35.
36.

2- trichomonas
3- bacteroids
Screening test for hemolytic anemia ?
HB, serum iron , ferritin
Which cytokine ll inhibit hpv replication
Interferons
Lyzozyme
Which process uses energy for myometrial contractionfrim electron transport chain
Oxidative phosphorylation
Krebs cycle
Most common microorganism that cause UtI
In post operative patient with catheter
a) pseudomonas
b) E. coli
c) proteus

Ans
Pseudomonas
37. CRL= 10mm
7wk,8wk , 10wk, 12wk
38. what structure can be easily identified at laprotomy passing through deep inguinal ring...
Ans
Round ligament
39. Level of bifurcation of aorta....??
Highest point on iliac crest
40. Endometrial biopsy shows decreased stroma no mitotic activity and small glands
1- proliferative
2-secretory
3-atrophic
4-luteal
5-follicular
41. In a Dexa bone mineral density scan the results are reported which two

ways?
T score (compares the individual to a young adult where normal is
greater
than 1) and Z score (compares the individual to another individual of
the same
age and gender)
T score (compares the individual to a young adult where normal is
greater
than 0) and Z score (compares the individual to another individual of the
same
age and gender)
Z score (compares the individual to a young adult where normal is
greater
than -1) and T score (compares the individual to another individual of
the same
age and gender)
Z score (compares the individual to a young adult where normal is
greater
than 0) and T score (compares the individual to another individual of the
same
age and gender)
Z score (compares the individual to a young adult where normal is
greater
than 2.5) and T score (compares the individual to another individual of
the same
age and gender)

Ans
1
42. Treatment in vaginal discahrge wirh MRSA + culture ,
Ans
iv vancomycin
43. There was a CTG question....base line HR 155, variability 5?, no acc or decel??Type of CTG
Ans
Suspicious
44. Cystic fibrosis detection ?
A)PCR
B)FISH
45. Patient with fever on 2nd post operative day with increased pulmonary vascular markings and
pleural effusions....1.pneumonia2.pneumothorax....??
Ans.........Pumonary edema
46. Hpv 16 and 18 responsible for ___ % of infections
1- 10%
2-40%
3-70%
4-100%
47. Soft haemorrhag ovarian tumour with call exner bodies
1- granulesa cell tumour
2- mucinus tumour
3- fibroma
ANS.............................1
48. Mechanism of contraception in medroxy progesterone I'm
1- affect sperm and ova
2- thick cervical mucus
49. Type 2 sbmucus fibroid
1- pedunclated fibroid in uterine cavity
2- 50% in uterine cavity
Other options
Ans
More than 20% in uterine cavity
50. Hystosalpingography
Some options and ask which is correct for it
1- it can be done within the first 10 days of proliferative phase
51. What abt AMH ?
Its androgenic
Produce from granulosa cells during reproductive period
Inhibit apoptosis
52. What is the cell that it is 2-5%
Of leukocytes??

Options are macrophages

Basophils
Nk cells
Neytrophil
Ans....................Eosinophils
53. Pregnant women
FBs 4.1
PP 7.4
Ans..................Normal

Fasting(5.1 to 6.9 mmol/L), 2 hour PP(8.5 to 11.0 mmol/L) latest WHO

guideline from UpToDate
54. Acute hemolytic reaction in blood tans caused by :
ABO incomp
Non-ABO anti-rbcs
55. Consent :
You should inform pt known risks

Person how give consent must be over 18

Concent form is not valid if is not signed
56. Which APCs are present in cervix
B lymphocytes
Plasma cells
Mast cells
Langerhans Cells

Ans
Langerhans Cells
57. What does amphipathic mean
Water and fat soluble ?
58. Hormone helpful in sodium absorption
Ans........Aldosterone
59. Vitamin needed for megaoblastic anaemia
Ans................Folic acid
60. Vitamin converting ferric to ferrous to aid Iron absoption
Ans.........Vit.C
61. Coprus luteum withdrawn at weeks pregnancy results in miscarriage.Which hormone
deficiency responsible? Hcg , Progesterone
Ans...............Progesteron
62. Maximum hCG at which age of gestation?
A)18-20 weeks
B)10-12 weeks
Ans
B
63. Androgen structure
C18
C19
C21
Ans.................C19
64. Uterus didephus results from failure of fusion of which structure?
A)Mesonephric duct
B)Paramesonephric duct

Ans
B
65. Anyone remember lymphatc drainage q of cervix and vagina in the table.?
66. Narrowest portion of fallopian tube
Isthmus
67. Chest x ray findings of a tuberculosis patient showing nodules
Which of the following cells is responsible?
A) lymphocytes
B) plasma cells
C) macrophages
D)Fibroblast
E)-?
68. Insulin gets active by removal of which peptide.
Options
A)C peptide
B) peptie

Ans
C peptide
69. hemolytic disease of new born d/t
mother+ fathermother + baby +
70. Lat wall of ischiorectal fossa?
A)Levator ani
B)Obturator internus muscle

71. Active form of Vitamin D?

Ans
1,25 cholcalciferol
72. UTI in 25 weeks of pregnancy.Microrganisms sensitive to Nitrofurantoin,Cephalosporin etc
TX?

Ans
iv Cephalosporins
73. Calculate Sensitivity?
Ans
75%
74. Pretem labour incidence 5% test done +ve likehood 14 and -ve likehood -2 percentage of -ve
women to have pretem labour....
75. Null hypothesis is accepted if
A)equvalnat to P value
B)If P=>0.05
76. Structure attached to Anterior superior iliac spine

Ans
Inuinal igament
77. In cytogenetics the commonly used is(SBA)
1-G-banding
2-M-banding
Ans
G-banding
78. Role of Glucocorticoids

Ans
Gluconeogenesis
79. Female with irregular cycle 3mnth developed amenorrhea hormone
Profile as fallow progestone15mlunit prolactin 1200m unt tsh I don't know value but in normal
range hcg 7600m.untthis value diagnosis ahyperprolactinemia
B pregnancy
C hypothyroidism
80. Irregular bleeding , which treatment you ll not give
Tranxemic acid
NSAIDs
Norethisterone at 21 to 28 day................Ans
Norethisterone at 1 to 21 day
81. pt developed genital prolapse after delivery of sizable baby.. the affected ligament?
82. what is a histogram ?you should know the definition
83. closure of ductus arteriosus following lung inflation shortly after birth is mediated by which
vasoactive substance ? SBA
bradykinin
prostacyclin
substance P
vasopressin
VEGF
Ans
Bradykinin
84. Down Syndrome quadruplet test
Ans
85. Pt post op brady caria machanishm of atropin receptor? which r
Ans
acteyl cholin
86. Complete mole karyotying
A)46 chromosome with maternal sex chromosomes

87. Kidney develops from

A)Mesonephros
B)Metanephros

88.
89.
90.
91.
92.

93.

94.
95.
96.

Ans
A
What value is represented by diamond shape graph
Ans
95% Confidence interval
Androgen produed by which cels
Ans
Theca cells
Female with recurrent 4th trimester miscarriges,what test sould be done
Ans
Thrombophilia screen
Vasectomy failure rate
Ans
1:200
CTG of patient shows fetal hypoxia,PH=7.28.What intervention
A)Cesarean section
B)FBS in 30 min
C)Dont repeat FBS unless CTG deteriorates
Ans
C
Both father and mother are homozygous for sickle cell .Effect on children?
A)S trait
B)Sickle cell disease
Ans
B
Free T3 in non pregnant woman
Ans
1%
Pethidine overdose what to monitor
Ans
Respiratoy rate
Polactin inhibitor dopamine agonist
A)Quetiapine
B) Quinagolide

C)Quinergoline
Ans
B
97. Muscles of pelvic diaphragm
Ans
Levator ani and Cocygeus
98. pt 10 year iucd c/o vaginal discharg which orginasim is respaseble for

infection bactiral vaginitis

A)Actinomyces Israli
99. pt pregnant 36?? c/o watery coming clear pt not in labor what is first
action on examination ? What shouldnt be done
A)/ fetal heart sound
B) p/v examination
Ans
B
100.Which structure is attached to anterior superior Iliac spine
A)Inguinal nerve
B)Pubococygeus
C)Inguinal ligament

Ans
C
101.Main suorting ligament of the Uterus
A)Cardinal ligament
B)Perineal Body
C)Broad ligament
Ans
?
102.

TRUE/FALSE
1.

2.

T/F
G potein coupled receptors
Options
A)Prostaglandin
Ans
A) T
Which of the following are true regarding the inferior vena cava
A)Drains Right Renal vein
B)Drains Left Ovarian vein
C)starts at the level of L5

D)lies behind the right external iliac artery

E)pierces the diaphragm in the central tendon
3.

4.

5.
6.
7.

8.

9.

T/F
Levator ani is attached to
A)Cervix
B)Ischial spine
c)Sarum
D)Symphysis Pubis
T/F
Regarding Pelvis
A)In female pelvis diameter of acetabulum is greater than the distane between acetabular rim
and sypmhysis pubis
B)Male sacral plane is more curved
T/F
Liver is more radiosensitive than intestines
Ans..............
T/F
Urodnamic study
Residual volume etc
B lymphocytes functions
1- antigen presenting to t lymphocytes
2-specific antibody mediated action
3-secrete interferons?
45True or false qs?
Which of the following are germ cell tumours?
1-dysgerminoma
2-cholangiocarcinoma
3-teratoma..
Which of the following tumours is hormone dependant t/f
1-adenocarcinoma breast
2-adenocarcinoma cervix?

3-prostate cancer
4-osteogenic sarcoma?
510. streptococci may cause(t/f)
1-toxic shock syndrome
2-acne vulgaris
3-arthralgia
11. T/F
FISH detect :
- klienfelter
- reciprocal translocation
- cystic fe
-?
-?
12. T/F
Correct pair
labetolol...........Beta adrenergic antagonist
Ans
T
13. Regarding Fetal Haemogobin
A)Fetal oxy diss curve lies to the left of mother

in the fetus (t/f)

1-Hbf is resistant to denaturation by alkali
2-fetal Hb dissociation curve lies to the right to that of the mother
3-maternofetal gradient of pco2 helps oxygen passage from mother to
fetus
4-haemopoiesis occurs in the yolk sac in the 1st 4 weeks
5-??
14. T/F

Ureter cross EIA infront sacro iliac joint

Ans..........F( it is common iliac)
15. True or false
Clomiphene:
1-anti-androgen
2- inhibits action of estrogen on hypothalamus
3-causes visual disturbances
4-?
5-?
16. t/f
Mitochondrial DNA
A)is intranucear
B)Resonsible for oxidative phosphorylation
C)is for cystic fibrosis
D)is in pairs

Ans
FTFT
17. T/F
Umblical Cord
A)Is 50cm in length
B)Has 2 veins one artery
C)Has a layer of amnion
D)Contains midgut during intrauterine life
E)
Ans

18. the following drugs inhibit the action of oral contraceptive pills:(t/f) 1-tetracycline 2phenobarbitone 3-cascara 4-digitalis 519. T/F
Which of the following antibiotics can be given orally t/f
A)- tetracycline
B)- chloramphenicol
C)-streptomycin
D)-Gentamycin
Ans
TTFF
20. T/F
Ultrasound
A)Frequency is about 120 MHz
B)Greater the frequency greater is the resolution
21. T/F
Regarding Pumonary Embolism which one is correct
A)It can be diagnosed on Xray angiogram
B)V/Q scan shouldnt be done in Pregnancy
C)ECG is reliable for diagnosis
D)Can be diagnosed by filling defect in water/air interface?
Ans
TFTT
22. smooth muscle
A. contains myosin and actin
B. can be up to 20mm
C. only stimulated my calcium
23. keton bodies
a) a fuel to the heart
b) used by the brain??
????
24. insulin(t/f)
1-mainly metabolized by kidny
2-increases with arginine
25. B lymphocytes (t/f)
1-produce TNF
2-produce complement
3-produce antibodies
4-contribute to delayed hyper sensitivity syndrome
5-produce igE
26. Ketone bodies
a) a fuel to the heart
b) used by the brain??
????
27. The following are synthethised by liver: (t/f)
A)glucagon
B)vit.A
C)cholesterol
D)immunoglobulins
E)prothrombin

Ans
FFTFT
28. Tue or false q... Fibroids are
1- leiomyxoma on histology
2- can be associated with polycythemia
3- can cause endometrial hyperplasia
4-?
5-?

29. salmonella typhi...

.. inhibited by gastric acid

.. affects humans only
..not denatured by refridgeration
30. Preimplantation screening?? Is done in?
31. Drugs that inhibit detrusor muscle
Propantheline
Atropine
Cabarchol
Distigmine
.???
32. Which of the following is normal in pregnancy true or false q
A) urine protein secretion of 150 mg/24hr
B)E.Coi of more than 10000 in urine
C)Iron of more than 20-40 mg in urine
33. Greater omentum t/f
A)Has gastroepiploic vessels
B)forms part of posterior surface of lesser sac
C)Attached to lesser curvature of stomach
D)
34. Estrogen
A)Helps in alveolar development
B)Causes milk producing effect
C)
35. Decidual cells secrete
A) hcg
B)prostaglandin
C) hpl
D)progesterone
36. The effect of radiation on the tumors
A)-more with hypoxia.
B)-more in the liver tissue than intestinal
C)-more in differentiated than in undiff
D)-with low temperature
E)-??
37.