Académique Documents
Professionnel Documents
Culture Documents
Module 3 :
Cell growth stoichiometry. Batch cultivation of cells- Growth cycle phases like lag, exponential
growth, maximum stationary phase, and death phase.
Medium formulation, yield factors, Monod growth kinetics.
Transport phenomena in bioprocess systems- gas- liquid mass transfer, metabolic oxygen
utilization, oxygen transfer rate determination, overall coefficients and power requirements in
sparged and agitated vessels. Heat transfer in biochemical reactions.
Bioreactor Instrumentation- physical and chemical sensors, gas analysis, online and offline
sensors.
Module 4 :
Design and analysis of biological reactors- Ideal reactors and non-ideal reactors, sterilization
reactors, multiphase reactors- packed type, bubble column, fluidized bed, fixed bed (general
description)
Fermentation technology- design and operation of typical aseptic aerobic fermentation process.
Different configurations for fermentors.
Product recovery operations- filtration, centrifugation, extraction, sorption, precipitation,
chromatography and membrane processes.
Bio-chemical industry- flow diagrams and descriptions for production of fine chemicals like
enzymes, proteins, antibodies, steroids. Flow diagrams and description for manufacture of beer,
wine. Fuel alcohol, ethanol, organic acids, amino-acids, and single cell proteins.
Reference Books
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