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Saquinavir
Zidovudine
Didanosine
Efavirenz
Enfuvirtide
e) Penicillin V
Q13. Which one of the following is a common early side effect of
Penicillin?
a) Constipation
b) Loss of appetite
c) Orthostatic hypotension
d) Atrioventricular block
e) Skin rash
Q14. Which of the following might be seen in patient of TB, who
has regularly been injecting intramuscular injection of
streptomycin:
a) Depression
b) Sialorrhea
c) Increased serum alanine aminotransferase
d) Priapism
e) Deafness
Q15. Significant negative interaction has been known to occur
between the following drugs if given concurrently:
a) Penicillin G & Penicillin V
b) Penicillin & tetracycline
c) Penicillin & Gentamycin
d) Penicillin & Clavulanic acid
e) Ticarcillin & Clavulanic acid
Q16. Which of the following is NOT a recognized complication of
ampicillin toxicity:
a) Hemolytic anemia
b) Diarrhea
c) Nausea
d) Overgrowth of gram-positive organisms
e) Ventricular fibrillation
Q17. Doctor is wrong when he suggests his patient to get drug:
a) Streptomycin by IV route
b) Gentamycin by IV route
c) Neomycin by oral route
d) Penicillin V by oral route
e) Cefepime by IV route
Q18. Telithromycin:
a) Is structurally related to tetracycline
b) Is structurally related to beta lactam antibiotics
c) Is structurally related to aminoglycosides (note: see an
animation on aminoglycosides mechanism of action)
d) Binds more tightly to ribosomes and so it is a poor substrate
d)
e)
minocycline
Ticarcillin
d)
e)
Cefazolin
Ampicillin
d) Rifampicin
e) Isoniazid
Q36. A 35 year old male recently diagnosed with tuberculosis and
is started on medication. After a few days he comes to the
emergency department a few hours after taking a meal at
McDonalds with severe pain in the big toe. Blood tests show a
very high uric acid level. Which of the following drugs most likely
caused these symptoms?
a) Streptomycin
b) Rifampicin
c) Isoniazid
d) Amikacin
e) Pyrazinamide
Q37. A 40 year old male taking medication for tuberculosis since
the last 2 months comes to the ENT OPD with complaint of
hearing problems and ringing in the years. The drug with which of
the following mechanisms of action is most likely causing these
symptoms?
a) Binds to 30 S Ribosome subunit & inhibits initiation
complex
b) Inhibits DNA Dependent RNA Polymerase
c) Inhibits synthesis of mycolic acid
d) Inhibits synthesis of arabinoglycan subunits
e) Inhibits DNA Gyrase
Q38. A 35 year old female taking medication for tuberculosis and
oral contraceptives comes to the Gynaecology OPD with
complaint of amenorrhea. Laboratory test shows a positive
pregnancy test. Which one of the following drugs most likely
caused her to become pregnant?
a) Rifampicin
b) Pyrazinamide
c) Streptomycin
d) Ethambutol
e) Isoniazid
Q39. A 45 year old male with diagnosed chronic liver disease gets
infected with the tuberculosis. Which one of the following drugs
would be most safe for this patient for the treatment of
tuberculosis?
a) Isoniazid
b) Rifampin
c) Pyrazinamide
d) Ethambutol
e) Ethionamide
Q40. A 48 year old male is diagnosed with tuberculosis and has
been treated for 2 months with isoniazid and rifampicin with good
response. But the patient develops numbness and paresthesias in
the extremities. What will you most likely do next?
a) Add pyridoxine
b) Stop isoniazid
c) Add vitamin E
d) Replace rifampin with ethambutol
e) Replace isoniazid with streptomycin
Q41. A 30 year old male presents with history of fever occurring in
a step-ladder fashion for the last 10 days. He also feels abdominal
pain after taking meals. Lab tests show decreased TLC count and
a positive Widal test. The drug which is most likely to be given
acts by which one of the following mechanisms?
a) Ciprofloxacin
b) Ampicillin
c) Cotrimoxazole
d) Cefixime
e) Azithromycin
Q42. A 35 year old pregnant woman presents to the gynecology
department with complaint of pain with rising fever since the last
5 days. Lab tests show gram negative bacilli and widal test comes
out positive. Which one of the following drugs will most likely be
administered?
a) Ciprofloxacin
b) Levofloxacin
c) Ofloxacin
d) Norfloxacin
e) Ampicillin
Q43. A 27 year old male football player gets injured in a match.
He comes to the emergency department with pain and swelling
near the ankle. On examination, there is small wound with a
tender swelling near the ankle joint. Further tests reveal tendon
rupture with tendonitis setting in. Which one of the following
antibiotics, if required, will most probably not be given to this
patient?
a) Ceftriaxone
b) Clarithromycin
c) Aminoglycoside
d) Ciprofloxacin
e) Amoxicillin
Q44. A 40 year old male comes to the medical OPD with
symptoms of cough & fever for the last few days. Sputum
culture shows presence of gram positive cocci. Which one of the
following Fluoroquinolones is most likely to be administered to
this patient?
a) Ciprofloxacin
b) Norfloxacin
c) Ofloxacin
d) Gatifloxacin
e) Levofloxacin
Q45. A 50 year old patient comes to the emergency department,
a day after he has been administered an antibiotic for an on-going
infection, with complaint of palpitations. ECG reveals prolonged
QT interval. Which one of the following Fluoroquinolones most
likely caused this adverse effect?
a) Ciprofloxacin
b) Norfloxacin
c) Levofloxacin
d) Ofloxacin
e) Gatifloxacin
Q46. Disinfectants are:
a) Strong chemical agents that inhibit or kill micro-organisms
b) Agents with sufficient toxicity for host cells
c) They kill both vegetative cells and spores
d) A process intended to kill or remove all types of microorganisms including spores and include viruses
e) A process that kills non-sporulating microorganisms by hot
water or steam at 65-100 C
Q47. A patient with watery stools is diagnosed as suffering from
amebic dysentery. He is given a drug that causes a metalic taste
in the mouth which drug may be given.
a) Iodoquinol
b) Diloxanide furate
c) Metronidazole
d) Pentamiline
e) Emetine.