Patients Initials: IBL

Age: 2 years Old

DOB: 2-13-15
Dx: Closed comp. disp. Subtroch
Right Femur

EMILIO AGUINALDO COLLEGE

School of Nursing and Midwifery
1113-1117 San Marcelino St. Ermita Manila

Miguel S. Datijan
EAC 3rd Year BSN

Name of Drug
Generic Name:

Classification
Pharmacologic Class:

Mechanism of Action
Therapeutic:

Indication
General Indication:

Acetaminophen

Antipyretic, Analgesic

Antipyretic: Reduces

Temporary reduction of

(Paracetamol)

Pregnancy Risk

fever by acting directly

fever, temporary relief

Trade/Brand Name:

Category:

on the hypothalamic

of minor aches and

Biogesic

Pregnancy Category C

heat-regulating center to

pains caused by

Patients Dose:

cause vasodilation and

common cold and

100mg/ 2ml q6 for pain

sweating, which helps

influenza, headache,

dissipate heat. Blocks

sore throat, toothache,

pain impulses by

backache, menstrual

inhibiting synthesis of

cramps, etc.

(For Pediatric)
maximum:

IV: 2 to 12
years: 15 mg/kg every 6 hours or
12.5 mg/kg every 4 hours
Maximum total daily dose: 75
mg/kg/day not to exceed 3750
mg/day
Oral: 10 to 15 mg/kg/dose every
4 to 6 hours as needed; do not
exceed 5 doses in 24 hours

Source:www.unilab.com

prostaglandin.
Pharmacokinetics:

Availability: For children

Onset: 10 minutes

aged 2-4 years: 180 mg

every 4-6 hours up to a
maximum of four doses daily.

Peak: 30 minutes to

Route(s) of
Administration: Oral,
IV, Rectal
Source: nurseslabs.com
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2 hours
Duration: 3 to 4
hours

Contraindication

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Side Effects

Nursing Responsibilities

Contraindication:
> Contraindicated with allergy to
acetaminophen
> Use cautiously with impaired hepatic
function, chronic alcoholism, pregnancy,
lactation.

Rare

Drug Interactions:
Anticonvulsant drugs People
chronically treated with anticonvulsants,
who overdose on paracetamol, are at
increased risk of liver damage because of

the increased metabolism of

paracetamol.
Certain antibiotics Chronic use of
isoniazid, an antibiotic drug often
prescribed for tuberculosis, may increase
the risk of liver damage when combined
with paracetamol even at recommended
safe doses.
Oral anticoagulants (blood thinners)
Paracetamol can possibly potentiate
the effects of blood thinners, increasing

Adverse Effect

Cholestyramine, a bile acid sequestrant

used for reducing blood cholesterol,

the risk of bleeding

Certain cholesterol-lowering agents

binds with acetaminophen thereby

preventing it from being absorbed by the

Bloody or black, tarry stools

bloody or cloudy urine
fever with or without chills (not
present before treatment and
not caused by the condition
being treated)
pain in the lower back and/or side
(severe and/or sharp)
pinpoint red spots on the skin
skin rash, hives, or itching
sore throat (not present before
treatment and not caused by
the condition being treated)
sores, ulcers, or white spots on
the lips or in the mouth
sudden decrease in the amount
of urine
unusual bleeding or bruising
unusual tiredness or weakness
yellow eyes or skin
Headache
Chestpain
Hepatic toxicity and failure,
jaundice
Acute renal failure, necrosis
Rash
Dyspnea
Hemolytic anemia
Hematuria

* Should not be used for self

medication of marked fever
(39.5C) This drug should not be
used for medicating fever
persisting for 3 days
* Do not exceed the
recommended dosage
* Reduce dosage with hepatic
impairment
* Avoid using multiple
preparations containing
acetaminophen. Carefully check
all OTC products
*Give drug with food if GI upset
occurs
*Discontinue drug if
hypersensitivity reactions occur
* Treatment of overdose: monitor
serum levels regularly, Nacetylcysteine should be available
as a specific antidote: basic life
support measures may be

body.

necessary.

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