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4282 Federal Register / Vol. 72, No.

19 / Tuesday, January 30, 2007 / Notices

DEPARTMENT OF HEALTH AND MSC 7850, Bethesda, MD 20892–7850, (301) Place: Embassy Suites Hotel Washington,
HUMAN SERVICES 435–1224, husains@csr.nih.gov. DC, 1250 22nd Street, NW., Washington, DC
Name of Committee: Center for Scientific 20037.
National Institutes of Health Review Special Emphasis Panel, Applied Contact Person: Julius Cinque, MS,
Metabolomic Technologies. Scientific Review Administrator, Center for
Center for Scientific Review, Notice of Date: February 21–22, 2007. Scientific Review, National Institutes of
Time: 8 a.m. to 5 p.m. Health, 6701 Rockledge Drive, Room 5186,
Closed Meetings MSC 7846, Bethesda, MD 20892, (301) 435–
Agenda: To review and evaluate grant
Pursuant to section 10(d) of the 1252, cinquej@csr.nih.gov.
applications.
Federal Advisory Committee Act, as Place: The Watergate, 2650 Virginia Name of Committee: Risk, Prevention and
amended (5 U.S.C. Appendix 2), notice Avenue, NW., Washington, DC 20037. Health Behavior Integrated Review Group;
Contact Person: Geoffrey White, PhD, Social Psychology, Personality and
is hereby given of the following
Scientific Review Administrator, Center for Interpersonal Processes Study Section.
meetings. Date: February 22–23, 2007.
The meetings will be closed to the Scientific Review, National Institutes of
Time: 8 a.m. to 5 p.m.
public in accordance with the Health, 6701 Rockledge Drive, Room 5148,
Agenda: To review and evaluate grant
provisions set forth in sections MSC 7849, Bethesda, MD 20892, 301–435–
applications.
2417, whitege@csr.nih.gov.
552b(c)(4) and 552b(c)(6), Title 5 U.S.C., Place: The Wyndham Hotel, 101 West
as amended. The grant applications and Name of Committee: Center for Scientific Fayette Street, Baltimore, MD 21201.
Review Special Emphasis Panel; Contact Person: Anna L. Riley, PhD,
the discussions could disclose
Fellowships: Bioengineering and Imaging. Scientific Review Administrator, Center for
confidential trade secrets or commercial Date: February 21–22, 2007. Scientific Review, National Institutes of
property such as patentable material, Time: 8 a.m. to 5 p.m. Health, 6701 Rockledge Drive, Room 3114,
and personal information concerning Agenda: To review and evaluate grant MSC 7759, Bethesda, MD 20892, 301–435–
individuals associated with the grant applications. 2889, rileyann@csr.nih.gov.
applications, the disclosure of which Place: National Institutes of Health, 6701 Name of Committee: Cardiovascular
would constitute a clearly unwarranted Rockledge Drive, Bethesda, MD 20892, Sciences Integrated Review Group;
invasion of personal privacy. (Telephone Conference Call). Myocardial Ischemia and Metabolism Study
Contact Person: Khalid Masood, PhD, Section.
Name of Committee: Center for Scientific Scientific Review Administrator, Center for Date: February 22–23, 2007.
Review Special Emphasis Panel, Psychiatric Scientific Review, National Institutes of Time: 8 a.m. to 1 p.m.
and Behavioral Genetics. Agenda: To review and evaluate grant
Health, 6701 Rockledge Drive, Room 5120,
Date: February 12–13, 2007. applications.
MSC 7854, Bethesda, MD 20892, 301–435–
Time: 8 a.m. to 4 p.m. Place: St. Gregory Hotel, 2033 M Street,
2392, masoodk@csr.nih.gov.
Agenda: To review and evaluate grant NW., Washington, DC 20036.
applications. Name of Committee: Infectious Diseases
and Microbiology Integrated Review Group; Contact Person: Joyce C. Gibson, DSC,
Place: Bethesda Marriott, 5151 Pooks Hill Scientific Review Administrator, Center for
Road, Bethesda, MD 20814. Prokaryotic Cell and Molecular Biology
Study Section. Scientific Review, National Institutes of
Contact Person: Cheryl M. Corsaro, PhD, Health, 6701 Rockledge Drive, Room 4130,
Scientific Review Administrator, Center for Date: February 21–22, 2007.
MSC 7814, Bethesda, MD 20892, 301–435–
Scientific Review, National Institutes of Time: 8:30 a.m. to 3 p.m.
4522, gibsonj@csr.nih.gov.
Health, 6701 Rockledge Drive, Room 2204, Agenda: To review and evaluate grant
applications. Name of Committee: Endocrinology,
MSC 7890, Bethesda, MD 20892, (301) 435– Metabolism, Nutrition and Reproductive
1045, corsaroc@csr.nih.gov. Place: Mayflower Hotel, 1127 Connecticut
Avenue, Washington, DC 20036. Sciences Integrated Review Group; Cellular,
Name of Committee: Center for Scientific Molecular and Integrative Reproduction
Review Special Emphasis Panel, Cancer Contact Person: Diane L. Stassi, PhD,
Study Section.
Immunopathology and Immunotherapy Scientific Review Administrator, Center for
Date: February 22–23, 2007.
Study Section: Quorum. Scientific Review, National Institutes of
Time: 8 a.m. to 2 p.m.
Date: February 15–16, 2007. Health, 6701 Rockledge Drive, Room 3202,
Agenda: To review and evaluate grant
Time: 8 a.m. to 5 p.m. MSC 7808, Bethesda, MD 20892, (301) 435– applications.
Agenda: To review and evaluate grant 2514, stassid@csr.nih.gov. Place: Doubletree Hotel Bethesda, 8120
applications. Name of Committee: Center for Scientific Wisconsin Ave, Bethesda, MD 20814.
Place: Bethesda Marriott, 5151 Pooks Hill Review Special Emphasis Panel; Contact Person: Syed M. Amir, PhD,
Road, Bethesda, MD 20814. Nanotechnology in Medicine and Biology— Scientific Review Administrator, Center for
Contact Person: Steven B. Scholnick, PhD, Synthesis, Theory and Analysis. Scientific Review, National Institutes of
Scientific Review Administrator, Center for Date: February 22–23, 2007. Health, 6701 Rockledge Drive, Room 6172,
Scientific Review, National Institutes of Time: 8 a.m. to 6 p.m. MSC 7892, Bethesda, MD 20892, 301–435–
Health, 6701 Rockledge Drive, Room 6152, Agenda: To review and evaluate grant 1043, amirs@csr.nih.gov.
MSC 7804, Bethesda, MD 20892, 301–435– applications. Name of Committee: Cell Biology
1719, scholnis@csr.nih.gov. Place: Doubletree Hotel Bethesda, 8120 Integrated Review Group; Nuclear Dynamics
Name of Committee: Molecular, Cellular Wisconsin Ave, Bethesda, MD 20814. and Transport.
and Developmental Neuroscience Integrated Contact Person: Nitsa Rosenzweig, PhD, Date: February 22, 2007.
Review Group; Molecular Scientific Review Administrator, Center for Time: 8 a.m. to 5 p.m.
Neuropharmacology and Signaling Study Scientific Review, National Institutes of Agenda: To review and evaluate grant
Section. Health, 6701 Rockledge Drive, Room 1102, applications.
Date: February 21–22, 2007. MSC 7760, Bethesda, MD 20892, (301) 435– Place: Holiday Inn Georgetown, 2101
Time: 8 a.m. to 5 p.m. 1747, rosenzweign@csr.nih.gov. Wisconsin Avenue, NW., Washington, DC
Agenda: To review and evaluate grant Name of Committee: Brain Disorders and 20007.
applications. Clinical Neuroscience Integrated Review Contact Person: Alessandra M. Bini, PhD,
Place: Jurys Washington Hotel, 1500 New Group; Neural Basis of Psychopathology, Scientific Review Administrator, Center for
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Hampshire Avenue, NW., Washington, DC Addictions and Sleep Disorders Study Scientific Review, National Institutes of
20032. Section. Health, 6701 Rockledge Drive, Room 5142,
Contact Person: Syed Husain, PhD, Date: February 22–23, 2007. MSC 7840, Bethesda, MD 20892, 301–435–
Scientific Review Administrator, Center for Time: 8 a.m. to 5 p.m. 1024, binia@csr.nih.gov.
Scientific Review, National Institutes of Agenda: To review and evaluate grant Name of Committee: Renal and Urological
Health, 6701 Rockledge Drive, Room 4188, applications. Studies Integrated Review Group;

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Federal Register / Vol. 72, No. 19 / Tuesday, January 30, 2007 / Notices 4283

Pathobiology of Kidney Disease Study Scientific Review, National Institutes of Place: National Institutes of Health, 6701
Section. Health, 6701 Rockledge Drive, Room 3152, Rockledge Drive, Bethesda, MD 20892,
Date: February 22–23, 2007. MSC 7770, Bethesda, MD 20892, 301–435– (Virtual Meeting).
Time: 8 a.m. to 5 p.m. 0906, kosse@csr.nih.gov. Contact Person: Weihua Luo, MD, PhD,
Agenda: To review and evaluate grant Name of Committee: Health of the Scientific Review Administrator, Center for
applications. Population Integrated Review Group; Scientific Review, National Institutes of
Place: The Churchill Hotel, 1914 Neurological, Aging and Musculoskeletal Health, 6701 Rockledge Drive, Room 5114,
Connecticut Avenue, NW., Washington, DC Epidemiology Study Section. MSC 7854, Bethesda, MD 20892, 301–435–
20009. Date: February 22–23, 2007. 1170, louw@csr.nih.gov.
Contact Person: Krystyna E. Rys-Sikora, Time: 8:30 a.m. to 2 p.m. Name of Committee: Center for Scientific
PhD, Scientific Review Administrator, Center Review Special Emphasis Panel, Genetics
Agenda: To review and evaluate grant
for Scientific Review, National Institutes of and Psychopathology.
applications and/or proposals.
Health, 6701 Rockledge Drive, Room 4016J, Date: February 22, 2007.
Place: Pier 5 Hotel, 711 Eastern Avenue,
MSC 7814, Bethesda, MD 20892, 301–451– Time: 2 p.m. to 3:30 p.m.
Baltimore, MD 21202.
1325, ryssokok@csr.nih.gov. Agenda: To review and evaluate grant
Contact Person: Heidi B. Friedman, PhD,
Name of Committee: Center for Scientific Scientific Review Administrator, Center for applications.
Review Special Emphasis Panel; Viral Scientific Review, National Institutes of Place: Sir Francis Drake Hotel, 450 Powell
Detection and Diagnostics. Health, 6701 Rockledge Drive, Room 1012A, Street, San Francisco, CA 94102.
Date: February 22–23, 2007. MSC 7770, Bethesda, MD 20892, (301) 435– Contact Person: Elisabeth Koss, PhD,
Time: 8 a.m. to 4 p.m. 1721, hfriedman@csr.nih.gov. Scientific Review Administrator, Center for
Agenda: To review and evaluate grant Scientific Review, National Institutes of
Name of Committee: Hematology Health, 6701 Rockledge Drive, Room 3152,
applications.
Place: National Institutes of Health, 6701 Integrated Review Group; Hemostasis and MSC 7770, Bethesda, MD 20892, 301–435–
Rockledge Drive, Bethesda, MD 20892, Thrombosis Study Section. 0906, kosse@csr.nih.gov.
(Virtual Meeting). Date: February 22, 2007.
Name of Committee: Bioengineering
Contact Person: Soheyla Saadi, PhD, Time: 8:30 a.m. to 6:30 p.m.
Sciences & Technologies Integrated Review
Scientific Review Administrator, Center for Agenda: To review and evaluate grant Group, Microscopic Imaging Study Section.
Scientific Review, National Institutes of applications. Date: February 23, 2007.
Health, 6701 Rockledge Drive, Room 3211, Place: Holiday Inn Chevy Chase, 5520 Time: 8 a.m. to 6 p.m.
MSC 7808, Bethesda, MD 20892, 301–435– Wisconsin Avenue, Chevy Chase, MD 20815. Agenda: To review and evaluate grant
0903, saadisoh@csr.nih.gov. Contact Person: Chhanda L. Ganguly, PhD, applications.
Scientific Review Administrator, Center for Place: Marriott Courtyard, San Francisco
Name of Committee: Center for Scientific
Scientific Review, National Institutes of Downtown, 299 Second Street, San
Review Special Emphasis Panel; Small
Health, 6701 Rockledge Drive, Room 4118, Francisco, CA 94105.
Business: Medical Imaging and Exploratory
MSC 7802, Bethesda, MD 20892, (301) 435– Contact Person: Ross D. Shonat, PhD,
Ultrasound.
1739, gangulyc@csr.nih.gov. Scientific Review Administrator, Center for
Date: February 22–23, 2007.
Time: 8 a.m. to 4 p.m. Name of Committee: Infectious Diseases Scientific Review, National Institutes of
Agenda: To review and evaluate grant and Microbiology Integrated Review Group; Health, 6701 Rockledge Drive, Room 1115,
applications. Host Interactions with Bacterial Pathogens MSC 7849, Bethesda, MD 20892, 301–435–
Place: Bahia Resort Hotel, 998 West Study Section. 2786, shonatr@csr.nih.gov.
Mission Bay Drive, San Diego, CA 92109. Date: February 22, 2007. Name of Committee: Center for Scientific
Contact Person: Leonid V. Tsap, PhD, Time: 8:30 a.m. to 6 p.m. Review Special Emphasis Panel;
Scientific Review Administrator, Center for Agenda: To review and evaluate grant Nanotechnology for Heart, Lung Blood
Scientific Review, National Institutes of applications. Disorders.
Health, 6701 Rockledge Drive, Room 5128, Place: Palomar Hotel, 2121 P Street, Date: February 23, 2007.
MSC 7854, Bethesda, MD 20892, 301–435– Washington, DC 20037. Time: 8 a.m. to 5:30 p.m.
2507, tsapl@csr.nih.gov. Contact Person: Marian Wachtel, PhD, Agenda: To review and evaluate grant
Name of Committee: Center for Scientific Scientific Review Administrator, Center for applications.
Review Special Emphasis Panel; Retinopathy Scientific Review, National Institutes of Place: Melrose Hotel, 2430 Pennsylvania
Studies. Health, 6701 Rockledge Drive, Room 3208, Ave., NW., Washington, DC 20037.
Date: February 22, 2007. MSC 7858, Bethesda, MD 20892, (301) 435– Contact Person: Alexandra M. Ainsztein,
1148, wachtelm@csr.nih.gov. PhD, Scientific Review Administrator, Center
Time: 8 a.m. to 5:30 p.m.
Name of Committee: Infectious Diseases for Scientific Review, National Institutes of
Agenda: To review and evaluate grant
and Microbiology Integrated Review Group; Health, 6701 Rockledge Drive, Room 5144,
applications.
Virology—A Study Section. MSC 7840, Bethesda, MD 20892, 301–451–
Place: The Mayflower Hotel, 1127
Date: February 22–23, 2007. 3848, ainsztea@csr.nih.gov.
Connecticut Avenue, NW., Washington, DC
20036. Time: 8:30 a.m. to 5 p.m. Name of Committee: Center for Scientific
Contact Person: Raya Mandler, PhD, Agenda: To review and evaluate grant Review Special Emphasis Panel, Clinical
Scientific Review Administrator, Center for applications. Hematology.
Scientific Review, National Institutes of Place: George Washington University Inn, Date: February 23, 2007.
Health, 6701 Rockledge Drive, Room 5217, 824 New Hampshire Ave., NW., Washington, Time: 8:30 a.m. to 4 p.m.
MSC 7840, Bethesda, MD 20892, 301–402– DC 20037. Agenda: To review and evaluate grant
8228, rayam@csr.nih.gov. Contact Person: Joanna M. Pyper, PhD, applications.
Scientific Review Administrator, Center for Place: Holiday Inn Chevy Chase, 5520
Name of Committee: Health of the Wisconsin Avenue, Chevy Chase, MD 20815.
Population Integrated Review Group; Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Room 3198, Contact Person: Chhanda L. Ganguly, PhD,
Behavioral Genetics and Epidemiology Study Scientific Review Administrator, Center for
Section. MSC 7808, Bethesda, MD 20892, (301) 435–
1151, pyperj@csr.nih.gov. Scientific Review, National Institutes of
Date: February 22–23, 2007. Health, 6701 Rockledge Drive, Room 4118,
Time: 8:30 a.m. to 5:30 p.m. Name of Committee: Center for Scientific MSC 7802, Bethesda, MD 20892, (301) 435–
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Agenda: To review and evaluate grant Review Special Emphasis Panel; MEDI/BMIT 1739, gangulyc@csr.nih.gov.
applications. Conflict Meeting.
Place: Sir Francis Drake Hotel, 450 Powell Date: February 22, 2007. (Catalogue of Federal Domestic
Street, San Francisco, CA 94102. Time: 10 a.m. to 1 p.m. Assistance Program Nos. 93.306,
Contact Person: Elisabeth Koss, PhD, Agenda: To review and evaluate grant Comparative Medicine; 93.333, Clinical
Scientific Review Administrator, Center for applications. Research, 93.306, 93.333, 93.337,

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4284 Federal Register / Vol. 72, No. 19 / Tuesday, January 30, 2007 / Notices

93.393–93.396, 93.837–93.844, 93.846– low, physiological and non-toxic notice will be treated as objections to
93.878, 93.892, 93.893, National concentrations of sodium nitrite are able the contemplated license. Comments
Institutes of Health, HHS). to increase blood flow and produce and objections submitted in response to
Dated: January 18, 2007. vasodilation by infused and nebulized this notice will not be made available
David Clary, routes of administration. Pulmonary for public inspection, and, to the extent
Hypertension (PH) occurs as a primary permitted by law, will not be released
Acting Director, Office of Federal Advisory
Committee Policy. or idiopathic disease as well as under the Freedom of Information Act,
secondary to a number of pulmonary 5 U.S.C. 552.
and systemic diseases, such as neonatal Dated: January 22, 2007.
[FR Doc. 07–368 Filed 1–29–07; 8:45 am]
PH and sickle cell disease. There is no Steven M. Ferguson,
BILLING CODE 4140–01–M
cure for pulmonary hypertension, a
Director, Division of Technology Development
nitric-oxide deficient state characterized and Transfer, Office of Technology Transfer,
by pulmonary vasoconstriction and National Institutes of Health.
DEPARTMENT OF HEALTH AND
systemic hypoxemia and therapies vary [FR Doc. E7–1378 Filed 1–29–07; 8:45 am]
HUMAN SERVICES
in efficacy and cost. Recent studies by
BILLING CODE 4140–04–P
National Institutes of Health NIH researchers and their collaborators
provided evidence that the blood anion
Prospective Grant of Exclusive nitrite contributes to hypoxic DEPARTMENT OF HEALTH AND
License: Use of Inhaled Nitrite Therapy vasodilation through a heme-based, HUMAN SERVICES
for the Treatment of Pulmonary nitric oxide (NO)-generating reaction
Conditions with deoxyhemoglobin and potentially National Institutes of Health
other heme proteins [Nature Medicine
AGENCY: National Institutes of Health, 2003 9: 1498–1505]. These initial results Prospective Grant of Co-Exclusive
Public Health Service, HHS. indicate that sodium nitrite can be used License: Prevention and Treatment of
ACTION: Notice. as a potential cost-effective platform Human Cancer and Tumors by
therapy for a wide variety of disease Inhibitors of Any or All of the
SUMMARY: This is notice, in accordance
indications characterized broadly by Adenosine Receptor Subtypes
with 35 U.S.C. 209(c)(1) and 37 CFR
constricted blood flow or hypoxia. Covered by the Licensed Patent Rights
404.7(a)(1)(i), that the National
These results have been further
Institutes of Health (NIH), Department AGENCY: National Institutes of Health,
corroborated by work in the neonatal
of Health and Human Services (HHS), is Public Health Service, HHS.
lamb model for PH. Inhaled sodium
contemplating the grant of an exclusive ACTION: Notice.
nitrite delivered by aerosol to newborn
license to practice the invention
lambs with hypoxic pulmonary SUMMARY: This is notice, in accordance
embodied in: PCT patent applications
hypertension elicited a rapid and with 35 U.S.C. 209(c)(1) and 37 CFR
PCT/US2004/21985 and PCT/US2004/
sustained reduction (65%) in hypoxia- 404.7(a)(1)(i), that the National
22232, filed July 9, 2004, both entitled
induced pulmonary hypertension. Institutes of Health (NIH), Department
‘‘Use of Nitrite Salts for the Treatment
Pulmonary vasodilation elicited by of Health and Human Services, is
of Cardiovascular Conditions’’ [HHS
aerosolized nitrite was contemplating the grant of a co-
Reference Number: E–254–2003/2–3–
deoxyhemoglobin- and pH-dependent exclusive license to practice the
PCT–01], to Aires Pharmaceuticals, Inc.,
and was associated with increased invention embodied in Patent
a portfolio company of ProQuest
blood levels of iron-nitrosyl- Applications U.S. 60/340,772, filed on
Investments LLC, Princeton, N.J. The
hemoglobin. Notably, short term 12/12/2001, U.S. 60/342,582, filed on
field of use of inhaled administration of
delivery of nitrite dissolved in saline 12/19/2001, PCT/US2002/036829, filed
nitrite salts for this exclusive license
through nebulization produced on 11/14/2002, and corresponding EP,
may be limited to the use of inhaled
selective, sustained pulmonary CA, AU, and JP filings, as well as U.S.
formulations of nitrite salts for the
vasodilation with no clinically 10/498,416, filed on 06/10/2004;
treatment of Pulmonary Hypertension
significant increase in blood entitled ‘‘Methods for using
and pulmonary and/or cardiopulmonary
methemoglobin levels. [Nature extracellular adenosine inhibitors and
conditions. The United States of
Medicine 2004 10: 1122–1127]. Method adenosine receptor inhibitors to
America is an assignee of the patent
of use claims for nitrite salt enhance immune response and
rights in these inventions.
formulations are directed to conditions inflammation’’, all by Michail V.
DATES: Only written comments and/or
associated with high blood pressure, Sitkovsky, and Akio Ohta, to Redox
application for a license, which are decreased blood flow and for the
received by the NIH Office of Therapies, Inc., having a place of
treatment of specific conditions such as business in Boston, MA. The patent
Technology Transfer on or before April pulmonary hypertension and other
2, 2007 will be considered. rights in this invention have been
indications. assigned to the United States of
ADDRESSES: Requests for a copy of the The prospective exclusive license will
patent application, inquiries, comments America.
be royalty bearing and will comply with
and other materials relating to the the terms and conditions of 35 U.S.C. DATES: Only written comments and/or
contemplated license should be directed 209 and 37 CFR 404.7. The prospective application for a license that are
to: Susan Carson, D.Phil., Office of exclusive license may be granted unless, received by the NIH Office of
Technology Transfer, National Institutes within 60 days from the date of this Technology Transfer on or before April
of Health, 6011 Executive Boulevard, published Notice, NIH receives written 2, 2007 will be considered.
Suite 325, Rockville, MD 20852–3804; evidence and argument that establishes ADDRESSES: Requests for a copy of the
ycherry on PROD1PC64 with NOTICES

E-mail: carsonsu@od.nih.gov; that the grant of the license would not patent application, inquiries, comments
Telephone: (301) 435–5020; Facsimile: be consistent with the requirements of and other materials relating to the
(301) 402–0220. 35 U.S.C. 209 and 37 CFR 404.7. contemplated license should be directed
SUPPLEMENTARY INFORMATION: The core Properly filed competing applications to: Cristina Thalhammer-Reyero, Ph.D.,
invention is the unexpected finding that for a license filed in response to this M.B.A., Office of Technology Transfer,

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