Drug Name/

Classification
Rifampicin

Dose

Action

Indicatio
ns
Treatment
of
pulmonary
tuberculos
is

Side Effects

600mg
PO OD

Inhibits DNA
dependent RNA
polymerase
activity in
susceptible
bacterial cells

1200mg
PO OD

Inhibits the
synthesis of
metabolites in
growing
mycobacterium
cells, impairing
cell metabolism
and causing
death

Treatment
of
pulmonary
tuberculos
is

Nausea
Vomiting
Abdominal
pain
Headache
Decreased
visual acuity
& color
discriminatio
n
(blue.green)

300mg
PO OD

Bactericidal
interferes with
lipid and nucleic
acid
biosynthesis in
activity

Treatment
and
prophylaxi
s of
tuberculos
is

Nausea
Vomiting
Jaundice
Fever

1500mg
PO OD

Bactericidal
against
Mycobacterium
tuberculosis;
exact
mechanism is
unknown

Treatment
of
tuberculos
is

Nausea
Vomiting
Diarrhea
Rashes

Antituberculoti
c Antibiotic

Ethambutol
Antituberculoti
c

Isoniazid
Antituberculoti
c

Pyrazinamide
Antituberculoti
c

Headache
Rash
Diarrhea
Fatigue

Nursing
Considerations
Watch closely for
sign of hepatic
impairment
If adverse GI
reaction occurs,
monitor
hydration
Monitor dug
effectiveness by
regularly
assessing for
improvement in
patients
conditions and
evaluating
culture and
sensitivity test
results.
Be alert for
adverse
reactions and
drug interactions.
Assess patients
infection before
starting therapy
by physical
examination and
culture And
sensitivity testing
Monitor patient
for improvement,
and evaluate
culture and
sensitivity test

Assess patient
for allergy to
pyrazinamide,
acute hepatic
disease, gout,
and diabetes
mellitus
Administer only
with in
conjunction with
other

Vitamin B6
Nutritional
supplement

50mg PO
OD

Blocks effects of
isoniazid
poisoning

Antidote
for
isoniazid
poisoning

Drowsiness
Paresthesia
Somnolence
Unstable gait

Bactrim DS

1 tablet
PO OD

Inhibits
susceptible
bacteria

Treating
infection
caused by
certain
bacteria
and to
prevent
certain
infections.

Loss
appetite
Nausea
Vomiting
Mild diarrhea

In
combinati
on with
other
antiretrovi
ral for the
treatment
of HIV-1
infection
Treatment
of HIV
infection
in
combinati
on with
other
antiretrovi
ral
In
combinati
on with
other
antiretrovi
ral for the
treatment
of HIV-1
infection
Preventing
and
treatment
of iron
deficiencie
s anemias

Headache
Depression
Vomiting
Jaundice

Rash
Headache
Dry skin
Diarrhea

Fever
Headache
Loss
appetite
Nausea

Vomiting
Constipation
Dark stool
Diarrhea

Antibiotic

Atazanavir

1 tablet
PO OD

Inhibits
processing of
viral protein in
HIV-infected
cells, preventing
the formation of
mature viruses.

1 tablet
PO OD

Inhibits HIV
protease
activity, leading
to decrease in
production of
HIV particles

Anti HIV drug

Antiretroviral

Ritonavir

Abacavir/Lami
vudine

1 tablet
PO OD

Antiretroviral

Ferrous Sulfate
Iron
preparation

1 tablet
PO OD

Inhibits the
activity of HIV-1
reverse
transcriptase,
stopping viral
DNA growth

Replaces iron,
elevate serum
iron
concentration
which then
helps to form

antituberculotic
Assess patient
before and after
drug therapy to
monitor drugs
effectiveness
Assess patients
infection before
therapy and
regularly
thereafter.
Obtain specimen
for culture and
sensitivity test
before giving first
dose.
Assess patient
for allergy for
any component
of the product,
hepatic
impairment,
signs of lactic
acidosis
Assess for allergy
to drug.
Assess BP, bowel
sounds and skin
color

Monitor glucose
level during
therapy
Watch for
hypersensitivity
reaction

Obtain baseline
assessment of
patients iron
deficiency before
starting therapy
Evaluate HGB,

Vitamin C

1 tablet
PO OD

Water soluble
vitamin

Colace
Laxative
Stool softener

Clexane
Antithrombotic
Anticoagulant

100mg
PO BD

40mg SC
OD

hemoglobin

(help build
up the
blood)

It is a highly
effective
antioxidant. It is
also required for
the growth and
repair of tissues
in all parts of
the body.

It helps
with
preventing
of
infection
eg. cold

Promotes
incorporation of
water into stool,
resulting in
softer fecal
mass.

Prevention
of
constipati
on

Inhibits
thrombus and
clots formation

Prevention
and
treatment
of various
thromboly
tic
disorders

Heartburn
Stomach
cramps
Diarrhea
Acid urine

Throat
irritation
Mild cramps
Diarrhea
Rash

Fever
Edema
Hemorrhage
Confusion

HCT levels and

reticulocyte
count during
therapy
Assess patient
before and after
drug
administration
and drugs
effectiveness
When giving for
urine
acidification,
check urine pH to
ensure
effectiveness.
Obtain history of
patients bowel
patterns before
and after
therapy.
Be alert for
adverse
reactions and
drug interactions.
Obtain history of
patients
coagulation
parameters
before starting
therapy
Be alert for
adverse
reactions and
drug interactions.