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Restoration of Iron by Humic Acid

Extensive Testing of Humic Substances in Hungary
Iron Restoration
Nutritional anaemia, of which iron deficiency is the greatest
cause, constitute the second most prevalent nutritional
deficiency in the world, second only to protein-energy
malnutrition. Iron deficiency anaemia affects primarily women
and children and individuals with chronic disease. This
nutritional deficiency respects neither social class nor
geographic situation, as it is present in both developed and
underdeveloped countries. Iron deficiency anaemia is a
condition in which the haemoglobin levels of red blood cells
are lowered, and the red cells become smaller and
deformed, thus reducing their oxygen-carrying capacity. The
most common cause is nutritional, including inadequate
absorption of iron due to poor iron intake and reduced
bioavailability. Iron loss from internal bleeding, low stomach
acid and mal-absorption are also important factors. The
standardised (Humic/Fulvic Acid) may be an effective way to
treat iron deficiency anaemia and maintain adequate
amounts of necessary minerals in proper balance for optimal
health.
The ability of the standardised (Humic/Fulvic Acid) to restore
iron levels and improve haematological parameters has been
documented. Serum iron levels improved in fourteen adult
volunteers given oral doses of (Humic/Fulvic Acid) during a
three-week period. Serum ferritin levels approached the
desired physiological range within three weeks. It was
reported that for subjects with low iron values at the
beginning of the study, their iron levels increased to within
the desired range for iron status; conversely, those subjects
who began the study with elevated iron status, their iron
levels decreased to within the desired physiological range.
This finding demonstrated that (Humic/Fulvic Acid) could
facilitate homeostasis of iron status in humans.
(Humic/Fulvic Acid) was given orally as an adjuvant during
cytostatic therapy to tumour patients. Cytostatic therapy is
used for the prevention of the growth and proliferation of
cancer cells; however, damage may also occur to normal
cells such as erythrocyte cells (red blood cells), which may
lead to anaemia (the deficiency of red blood cells,
haemoglobin, and blood volume). Therefore, iron therapy is
needed, because iron functions as a part of haemoglobin and
thus red blood cell function. One group of patients showed
significant enough improvement in their erythrocyte counts
so that no further need for iron therapy was required. Further
subjective evidence of benefits experienced by these cancer
patients included: improved appetite, weight gain, reduced
need for analgesics, increased general stress resistance,
reduced nausea, reduced fatigue, and restoration of the
capacity to work. No adverse side effects were reported that
could be attributed to (Humic/Fulvic Acid).
The standardised (Humic/Fulvic Acid) formula was used for
the treatment of anaemia and for faster recovery from
illnesses in children. Nineteen paediatric subjects with iron
deficiency anaemia were studied to determine if
(Humic/Fulvic Acid) given orally would improve their general
well-being, appetite, and serum iron levels. Subjects reported
improvements in appetite and well-being after treatment with
(Humic/Fulvic Acid). A rise in serum iron levels was seen as
early as two weeks after administration had begun. After
three weeks, (Humic/Fulvic Acid) caused a significant
increase in the serum iron level. Haemoglobin levels were
variable, with some rising and others decreasing, but within
desired physiological levels.
This same effect (variable haemoglobin levels) was also
manifest in elite athletes. Haemoglobin levels were studied to
determine if the oral administration of (Humic/Fulvic Acid)
would affect stress resistance, and the ability to increase the
intensity of exercise, following oral administration of
(Humic/Fulvic Acid) in 25 elite adult athletes. Haemoglobin
levels in the athletes remained within the desired
physiological range. Athletes reported a subjective
improvement in stress resistance and their ability to focus
during exercise periods. From the two previous studies, it
appears that the standardised (Humic/Fulvic Acid) may have
the ability to normalise iron, serum ferritin, and haemoglobin
levels. Evidence for the effect of (Humic/Fulvic Acid)'s iron
normalising capabilities has been described in the literature.
Protocatechuic acid (a phenolic monomer of (Humic/Fulvic
Acid)) can form Fe+2-polyphenol complexes when excess
amounts of iron are available. This occurs so that excess iron
(Fe+2) cannot react with oxygen molecules and form reactive
oxygen species. This provide further support for the metal
chelating activity of (Humic/Fulvic Acid) and implies that it
has the ability to normalise iron levels so that excessive
oxidation does not occur in the presence of higher than usual
amount of iron.
In vivo studies have also demonstrated the effectiveness of
the standardised (Humic/Fulvic Acid) for improving iron
deficiency anaemia in rats and pigs. (Humic/Fulvic Acid) was
tested on an iron deficient rat model by rearing the mothers
and their offspring on an iron free diet. Iron deficiency was
signified by severe microcytic, hypochromic anaemia, and
high zinc protoporphyrin (ZP) levels indicating the lack of iron
at tissue level in the bone marrow. The iron deficient rat pups
also exhibited a decreased weight at birth, decreased body
mass gain, and increased lethality compared to controls [69].
(Humic/Fulvic Acid) was compared to the effectiveness of an
official medicinal preparation, Aktiferrin syrup, which is
commonly used in the treatment of iron deficiency anaemia.
Regarding the haemopoietic and hepatic effects, measured
by red blood cells (RBC), mean cell volume (MVC),
haemoglobin (Hb), haematocrit (Hct), total iron binding
capacity (TIBC), transferring saturation, and liver enzymes
(ALAT, ASAT, GOT, GPT) respectively, (Humic/Fulvic Acid)
exhibited equal effects compared to the Aktiferrin. However,
(Humic/Fulvic Acid) proved to be superior in that body mass
gain of the pups was better in this group as compared to the
Aktiferrin group. Additionally, serum triglyceride levels were
measured, and decreased concentrations normalised in the
standardised (Humic/Fulvic Acid) formula group but not in the
Aktiferrin treated group.
Further support for the beneficial effects of the standardised
(Humic/Fulvic Acid) in the treatment of iron deficiency
anaemia has been demonstrated in iron deficient pigs. Pigs
of iron deficient sows that were fed the standardised
 (Humic/Fulvic Acid) while pregnant exhibited significantly
higher haemoglobin levels than did the pigs of iron deficient
sows that were given the standard parenteral iron
supplement treatment or no treatment. These results and
previous in vivo data indicate that the standardised
(Humic/Fulvic Acid) offers an effective treatment for iron
deficiency and may help restore impaired metabolic
processes due to iron deficiency anaemia.
*HumicHealth.info EDITOR'S NOTE:
In keeping with this website's intention to educate without
promoting or endorsing any Humic Acid product, we have
substituted the terms (Humic/Fulvic Acid) and (the product)
when reference to a brand name or formulation is made in
the above text.

DISCLAIMER: This website presents a collection of statements from around the world
about the benefits of Humic Acid. This information is provided for informational purposes
only. These statements were variously made over several decades of time. There are many
sources of Humic Acid around the globe, and they differ significantly in their physical and
chemical properties. This website does not intend to provide medical advice, nor does it
intend to suggest that all Humic Acid preparations will be of equal benefit. Nothing herein is
intended to be an endorsement of or a solicitation to purchase any particular Humic Acid
preparation. The FDA has not evaluated any statement made on this website. The
information herein is not intended to diagnose any disease, nor is it intended to prescribe
any preparation that claims to diagnose, treat, cure or prevent any disease.

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