Pathophysiology

Brain

DEFICIENCIES IN NEUROTRANSMITTER
htrauma

Acetylcholine somatostatin Nor Repeated Genetic

epinephrine head
trauma

Degeneration of brain cells

amyloid neurofibrillatory ganuvacuolar

plaques(neurotic/senil tangles degeneration
e plaques

Linked to areas of Temporal & parietal Degeneration of

cerebral cortex cortices neurons in
assoc. with hippocampus
cognition

Interferes w/ nutrient Memory, learning, Vacuoles enlarge the

exchange & disrupts fear aggression & cell body
blood: brain barrier thinking

Abnormally Neuron malfunction

Marked reduction in phosphorylated NFT’s
acetyltransferase or DEATH

Instability of all
Decreased Ach structures

Disturbance of the
normal functioning of
the brain