Combur Test parameters

How to do it
Collect urine sample in clean, sterile specimen container (preferably a dispos able cup).
Dip test strip into urine for not more than 1 second.
When withdrawing the strip wipe side edge of the test strip along the rim of vessel to remove excess urine.
After 60 seconds (leukoc ytes 60 120 seconds), compare reaction colours of the test patches with the colour
scales on the label.
Colour changes appearing only at the edges of the test patch or developing after more than 2 minutes are not
relevant for diagnosis.
Some dos of urinalysis
Use only clean, sterile urine specimen containers. Preferably disposable cups.
Examination of the urine with test strips should be carried out as soon as possible, but within 2 hours
at the latest. Mix the sample first.
Always store the sample in the fridge (+4 C) if the urine test cannot be performed within 2 hours.
The sample must be at room temperature for the test. Mix it first.
Close the tube again immediately after removing the test strip.
Store the test strips at a temperature between +2 and 30 C.
Dont forget to write the patients name on the urine specimen cup.
Some donts of urinalysis
Cleaning agents and disinfectants can distort results (false positive findings for blood and glucose).
Freezing or centrifuging the urine destroys leucocytes and erythrocytes and renders the s ample
useless for further microscopic examination.
If the urine is allowed to stand at room temperature for more than 2 hours, the composition
changes (greatly increased bacterial growth). Never place the sample in direct sunlight.

Ascorbic acid no problem with the Combur-Test Product Line

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2010 Roche
Roche Diagnostics Ltd. CH-6343 Rotkreuz Switzerland www.roche.com

pH
Clinical aspects
urinary tract infections
acidosis, or ketoacidosis
starvation
diarrhoea

Leucocytes
Clinical aspects
pyelonephritis
glomerulonephritis
cystitis
urethritis
bacterial infections

Protein
Clinical aspects
diabetes mellitus
fasting
vomiting
inborn errors of metabolism
ketoacidosis
Ketones
Clinical aspects
diabetes mellitus
fasting
vomiting
inborn errors of metabolism
ketoacidosis

Bilirubin
Clinical aspects
cirrhosis of the liver
intra- and extrahepatic
obstructive jaundice
hepatocellular jaundice

Nitrate
Clinical aspects
urinary tract infections
cystitis
pyelonephritis

Glucose
Clinical aspects
diabetes mellitus
renal/alimentary glycosuria
glycosuria in renal damage

Urobilinogen
Clinical aspects
cirrhosis of the liver
viral hepatitis
haemolytic anaemia

Blood
Clinical aspects
tumours of the bladder and
kidneys
urinary stone formation
glomerulonephritis
pyelonephritis
renal infarction
renal cysts
gouty kidneys

05164966001b 0210 - X.x XX

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Specific gravity
Clinical aspects
reduced concentrating ability of
the kidneys e.g. due to diabetes
mellitus or ADH deficiency