PP2231 Micro Tutorial 3

Question 1
The manifestation of infectious disease is dependent upon a balancing act between what two attributes of
players
a.
b.
c.
d.

reservoir of infection and mode of transmission.

port of entry and mode of transmission.
the virulence of the microbe and susceptibility of the host.
the virulence of the host of the susceptibility of the microbe.

Question 2
Trimethoprim is a member of which class of antimicrobial agents and how does it work to kill bacteria?
a.
b.
c.
d.

Protein synthesis inhibitor; it interferes with mRNA

Nucleic acid inhibitor; it interferes with folate synthesis
Plasma membrane detergent
Cell wall synthesis inhibitor; it interferes with peptidoglycan synthesis

Question 3
Aminoglycoside (gentamicin) therapy is common in people with Gram negative bacterial sepsis; altering
the standard dose regime to compensate for its toxicity if often required. Patients with which medical
condition need the dose altered (and why?)
a.
b.
c.
d.

folate deficiency.
super infection.
allergy.
renal impairment.

Question 4
The azole drugs such as clotrimazole treat tinea. The organisms that cause tinea are collectively called
dermatophytes. The organisms that cause tinea are acquired in which manner
a.
b.
c.
d.

zoophilic transmission.
geophilic transmission.
anthropophilic transmission .
a, b and c are all potential modes of transmission

Question 5
What is the most common cause of preventable blindness in Australia (and why)?:
a.
b.
c.
d.

Streptococcus pneumonia and Haemophilus influenzae.

Moraxella catarrhalis.
Pseudomonas aeurginosa.
Chlamydia trachomatis

Question 6
Impetigo is caused by Staphylococcus aureus. It is an example of what type of skin infection?
a.
b.
c.
d.

disseminated infection that localises in the skin.

infection where transient skin flora exploiting a breach in skin.
infection where disseminated toxin causes tissue damage and inflammation.
dermatophyte infection.

Question 7
Streptococcus pyogenes causes both pharyngitis and skin infection; the host immune response to this
pathogen sometimes can cause damage to the host; this is particularly prevalent in aboriginal
communities. A common complication of this infection is what (and why?)?
a.
b.
c.
d.

rheumatic heart disease.

reactive arthritis.
diphtheria.
epiglottitis.

Question 8

The pathophysiology of polymicrobial pelvic inflammatory disease may include:

a.
b.
c.
d.

multiple episodes of primary cervicitis

decreased sexual activity at a young age
decreased zone of ectopy on the surface of the cervix
all of the above

Question 9
What methods are recommended to treat instruments that might be contaminated with CJD (prion)?
a.
b.
c.
d.

steam sterilisation 121 C for 15 minutes

0
soak in glutaraldehyde the steam sterilise at 121 C for 15 minutes
0
boil at 100 C for 2 hours
0
steam sterilise at 134 C for 20 minutes

Question 10
Which of the four issues below could be linked with developing resistance of Mycobacterium tuberculosis
to antimicrobials (and why?)?
a. environmental exposure
b. presence of an insect vector
c. poor patient compliance to therapy
d. use of narrow spectrum drugs