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Summary
Background Up-to-date evidence on levels and trends for age-sex-specic all-cause and cause-specic mortality is
essential for the formation of global, regional, and national health policies. In the Global Burden of Disease Study
2013 (GBD 2013) we estimated yearly deaths for 188 countries between 1990, and 2013. We used the results to assess
whether there is epidemiological convergence across countries.
Methods We estimated age-sex-specic all-cause mortality using the GBD 2010 methods with some renements to improve
accuracy applied to an updated database of vital registration, survey, and census data. We generally estimated cause of
death as in the GBD 2010. Key improvements included the addition of more recent vital registration data for 72 countries,
an updated verbal autopsy literature review, two new and detailed data systems for China, and more detail for Mexico, UK,
Turkey, and Russia. We improved statistical models for garbage code redistribution. We used six dierent modelling
strategies across the 240 causes; cause of death ensemble modelling (CODEm) was the dominant strategy for causes with
sucient information. Trends for Alzheimers disease and other dementias were informed by meta-regression of
prevalence studies. For pathogen-specic causes of diarrhoea and lower respiratory infections we used a counterfactual
approach. We computed two measures of convergence (inequality) across countries: the average relative dierence across
all pairs of countries (Gini coecient) and the average absolute dierence across countries. To summarise broad ndings,
we used multiple decrement life-tables to decompose probabilities of death from birth to exact age 15 years, from exact age
15 years to exact age 50 years, and from exact age 50 years to exact age 75 years, and life expectancy at birth into major
causes. For all quantities reported, we computed 95% uncertainty intervals (UIs). We constrained cause-specic fractions
within each age-sex-country-year group to sum to all-cause mortality based on draws from the uncertainty distributions.
Findings Global life expectancy for both sexes increased from 653 years (UI 650656) in 1990, to 715 years
(UI 710719) in 2013, while the number of deaths increased from 475 million (UI 468482) to 549 million
(UI 536563) over the same interval. Global progress masked variation by age and sex: for children, average absolute
dierences between countries decreased but relative dierences increased. For women aged 2539 years and older than
75 years and for men aged 2049 years and 65 years and older, both absolute and relative dierences increased.
Decomposition of global and regional life expectancy showed the prominent role of reductions in age-standardised death
rates for cardiovascular diseases and cancers in high-income regions, and reductions in child deaths from diarrhoea,
lower respiratory infections, and neonatal causes in low-income regions. HIV/AIDS reduced life expectancy in southern
sub-Saharan Africa. For most communicable causes of death both numbers of deaths and age-standardised death rates fell
whereas for most non-communicable causes, demographic shifts have increased numbers of deaths but decreased agestandardised death rates. Global deaths from injury increased by 107%, from 43 million deaths in 1990 to 48 million in
2013; but age-standardised rates declined over the same period by 21%. For some causes of more than 100 000 deaths per
year in 2013, age-standardised death rates increased between 1990 and 2013, including HIV/AIDS, pancreatic cancer, atrial
brillation and utter, drug use disorders, diabetes, chronic kidney disease, and sickle-cell anaemias. Diarrhoeal diseases,
lower respiratory infections, neonatal causes, and malaria are still in the top ve causes of death in children younger than
5 years. The most important pathogens are rotavirus for diarrhoea and pneumococcus for lower respiratory infections.
Country-specic probabilities of death over three phases of life were substantially varied between and within regions.
Interpretation For most countries, the general pattern of reductions in age-sex specic mortality has been associated
with a progressive shift towards a larger share of the remaining deaths caused by non-communicable disease and
injuries. Assessing epidemiological convergence across countries depends on whether an absolute or relative measure
of inequality is used. Nevertheless, age-standardised death rates for seven substantial causes are increasing, suggesting
the potential for reversals in some countries. Important gaps exist in the empirical data for cause of death estimates
for some countries; for example, no national data for India are available for the past decade.
Funding Bill & Melinda Gates Foundation.
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Introduction
118
Methods
Study design
The GBD approach to estimating all-cause mortality
and cause-specic mortality has been previously
described.2,3 Here, we describe several renements.28
Figure 1 shows the general analysis of all-cause
mortality and cause-specic mortality and their
interactions. GBD 2010 included 291 causes of death or
disability, of which 235 were causes of death; we have
expanded the list to include 306 causes of death or
disability, of which 240 are causes of death. The extra
causes were added on the basis of three considerations:
(1) causes that were for epidemiological reasons already
modelled separately but reported combined with other
causes in GBD 2010for example, silicosis, asbestosis,
anorexia nervosa, and typhoid and paratyphoid fever;
(2) the category of other unintentional injuries was
large and heterogeneous so we broke it down further to
include pulmonary aspiration and foreign body in
trachea or lung, foreign body in other part of body, and
unintentional suocation; and (3) new datasets became
available to enable estimation of mesothelioma, new
maternal sub-causes, neonatal haemolytic anaemia,
and chronic kidney disease caused by glomerulonephritis. Appendix pp 245251 provides the
International Classication of Diseases codes for the
GBD 2013 cause list. After broad consultation, we have
removed from the cause list the pathogen-specic
causes of diarrhoeal diseases and lower respiratory
infections. Instead, we analysed these causes with a
counterfactual approach.
We assessed 21 regions and seven super-regions as
dened in the GBD 2010. The GBD 2013 also included
an assessment of subnational populations in
three countries: provinces for China, states for Mexico,
and the UK broken down into Scotland, Wales,
Northern Ireland, and nine regions of England. We
analysed these countries subnationally because of the
interest from national collaborators and because
sucient data were made available by the teams in each
country. In future iterations of the GBD, we hope to
include further subnational breakdowns. In addition,
we separately analysed data sources for rural and urban
regions in India. This approach improved our
estimation of mortality and causes of death and enabled
us to analyse causes of death that were specic to urban
or rural regions alone.
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Articles
All-cause mortality
Cause-specic mortality
Vital registration,
sample registration
Cause of death
database
Complete birth
histories
Noise
reduction
Redistribution
Cause
mapping
Verbal autopsy
data
Under-5 mortality
estimation
Vital registration
(ICD 9, BTL, ICD 10)
Noise
reduction
MI ratio
Redistribution
Cause
mapping
Cancer
registries
Summary birth
histories
Maternal
surveillance
Household surveys
Vital registration,
sample registration
CODEm
Negative
binomial/xed
proportion
DisMod
Other (ie, burial or
mortuary and census
Adult mortality
estimation
Maternal census
Sibling history
CoDCorrect
algorithm
Police data
HIV-free
life table
Age pattern of
excess mortality
from HIV
National registries
YLLs
Natural history
models
Non-shock
life tables
Intervention
coverage
Consistency adjustment
from EPP-Spectrum for
CoDCorrect
Non-shock
age-specic
mortality
Prevalence
Cause-specic
mortality
Age-specic and
sex-specic
death numbers
Key
Source data
Process
Results
Database
Covariates
We estimated national time series (19802013) for a range
of covariates with data from surveys (household-level and
individual-level data), censuses, ocial reports,
administrative data, and a systematic review. For lagged
distributed income and education, we estimated national
time series from 1950, to 2013. Details of how we imputed
series for GDP, educational attainment, tobacco prevalence,
and obesity prevalence have been published previously.2932
Appendix (pp 49614974) shows the sources and imputation
methods used to generate time series for each covariate.
Generally, we estimated uncertainty in covariate values
when sucient information was available.
All-cause mortality
We analysed all-cause mortality for 188 countries from 1950
to 2013; we present only results for 19902013 to coincide
with the period of the overall GBD 2013 assessment. As a
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(t), age (a), and sex (s) combinations. 08 was the highest
observed cause fraction caused by HIV in any age group
in any vital registration system. We selected from the
uncertainty ranges for HIV and all-cause mortality
those that minimised the dierence. If no draws had a
positive loss function, we sampled randomly from all
matched draws.
The CoDCorrect algorithm includes HIV/AIDS
cause-specic mortality and can alter the age and time
distribution of deaths from HIV/AIDS. To incorporate
the overall change in the number of HIV/AIDS deaths
over the course of the epidemic in a country implied by
the application of the CoDCorrect algorithm, but not to
distort the Spectrum estimated time and age pattern, we
adjusted the entire HIV/AIDS epidemic up or down on
the basis of the cumulative eects of CoDCorrect on
HIV/AIDS for all estimated years in each country.
Seventh, we used the same method as Wang and
colleagues2 to generate child mortality rate and adult
mortality rate for natural disasters and armed conicts.
We obtained data for conict and war, including deaths
from one-sided violence, non-state conict, armed force
battles, and other national or international conicts, from
the Uppsala Conict Data Program41 and the International
Institute for Strategic Studies.42 Further data for war were
obtained from countries vital registration systems and
classied as caused by war.43 We included disaster data
from the International Disaster Database from the Center
for Research on the Epidemiology of Disasters (University
of Louvain, Brussels, Belgium).44 From this database, we
included deaths caused by complex disaster, drought,
earthquake, ood, and others. When these databases
were not fully up-to-date or did not contain shocks known
to exist, we supplemented with case-by-case sources.
These with-shock mortality rates were then used as entry
parameters to the GBD relational model life-table system
to generate age-specic mortality rates with the eect of
shocks added.
Eighth, we used age-specic and sex-specic death
rates from the life-table to generate numbers of death by
multiplying by population estimates from the World
Population Prospects 2012 revision45 and the Human
Mortality Database for people older than age 5 years. For
the under-5 age groups, we applied the method of Wang
and colleagues.33 In some cases, assumptions in the UN
estimation process led to implausible population
numbers for some countries and age groupsfor
example, low population estimates for older age groups
in South Africa, especially for the most recent years.
For GBD 2013, we applied a Bayesian population
reconstruction model46 to re-estimate population for
South Africa for 19702013.
All geographies
GBD 2010
GBD 2013
GBD 2013
Dierence
National
State, province,
or region*
Local
Vital registration
2798
5039
2241
2765
2112
162
Cancer registry
2715
3860
1145
1216
979
1665
Sibling history
1557
1798
241
1788
10
Police records
1129
1433
304
1429
Surveillance
128
1430
1302
73
1074
283
Verbal autopsy
486
538
52
110
428
154
146
94
52
8967
14 244
7475
4166
2603
Total
5277
GBD=Global Burden of Disease Study. *Data were analysed at the state level for Mexico, the province level for China,
and the region level for the UK. Signicant increase because of incorporation of subnational sites in China, Mexico,
and the UK. Decrease caused by omission of World Health Survey data where adequate vital registration data was
available for GBD 2013.
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No data
14 site-years
514 site-years
1524 site-years
2534 site-years
35 site-years
ATG
VCT
Barbados
Comoros
West Africa
Dominica
Caribbean
LCA
Grenada
TTO
Maldives
TLS
Mauritius
Seychelles
Marshall Isl
Kiribati
Solomon Isl
FSM
Vanuatu
Samoa
Fiji
Tonga
Eastern
Mediterranean
Malta
Persian Gulf
Singapore
Balkan Peninsula
Articles
Posterior mean = (
2
2
X + 2 2 )
2
+
+
2
Posterior variance = (
2 2
2 + 2
25
Garbage coded
Usable cause
Deaths (millions)
20
15
10
19
1990
1991
1992
19 93
9
19 4
19 95
96
19
19 97
9
19 8
9
20 9
2000
2001
2002
20 03
2004
20 05
0
20 6
20 07
2008
0
20 9
2010
2011
2012
13
Year
Articles
124
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these models into estimates that are consistent with allcause mortality for each age-sex-country-year group. For
each cause-specic model and for all-cause mortality, we
had 1000 draws from the posterior distribution for each
age-sex-country-year group. We combined causes by
taking a random draw without replacement from the
posterior distribution of each cause and all-cause
mortality. Each cause was rescaled by a scalar equal to the
draw of all-cause mortality divided by the sum of the
draws of individual causes. The GBD 2010 induced a
correlation of 10 between the sum of cause-specic and
all-cause mortality. CoDCorrect was applied in a
hierarchical fashion: rst to level 1 causes and then to
level 2 and level 3 causes. Level 2 causes were constrained
to sum to the level 1 parent cause. Levels of this cascade
were largely the same as those used in the GBD 2010 and
were chosen on the basis of the amount and quality of
available data for cause of death.
For GBD 2013, we made slight modications to this
approach. Because tests showed no substantial eect of the
10 correlation between draws of all-cause mortality and
the sum of individual causes and because each cause is
modelled independently such that the ordering of draws
across causes were unrelated, we have removed this
assumption. Furthermore, because the modelling of HIV
through the GBD version of Spectrum uses relationships
between incidence, CD4 progression, and death that are
age-dependent and antiretroviral therapy scale-up over
time has had major eects, we modied the way in which
HIV deaths are handled in CoDCorrect. We ran
CoDCorrect for all causes and then computed the
pre-CoDCorrect cumulative deaths over time and age and
compared with the cumulative deaths post-CoDCorrect.
This provided an overall scalar, which we used to adjust the
entire HIV epidemic. To avoid in any age-sex-country-year
the sum of individual deaths exceeding all-cause mortality,
we computed the dierence between the cumulatively
scaled HIV deaths and the CoDCorrect HIV deaths and
added this dierence to the estimate of all-cause mortality
at the draw level.
In GBD 2010, diarrhoea deaths and lower respiratory
infection deaths were reported for pathogen-specic
causes in tabulations that summed to 100% of each parent
cause. Since the GBD 2010, the GEMS study56 has been
published, which provided data for the relative risk of
diarrhoea being related to dierent pathogens. This
relative risk approach used a dierent conceptual
framework than did the International Classication of
Diseases approach for underlying cause. Underlying
cause follows the more than 200-year history of health
statistics of assigning each death uniquely to a single
underlying cause. The relative risk approach follows the
approach used more generally for risk factors, where
cause is assigned based on comparison to a counterfactual.
Counterfactual attribution to specic risks or in this case
pathogens, can sum to more or less than 100%. On the
basis of the GEMS study and consultations among
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1
)
odds ratioi
Articles
1000 draws, which were used for all the other countries
in this region. Because GEMS included only diarrhoea
in children younger than 5 years, we applied the odds
ratio of pathogens calculated for children aged
25 years when calculating for adults. We did not
assign diarrhoea cases or deaths to a pathogen for an
age-country-year if more than 95% of draws were
greater than 1.
For cholera, we used data from previous studies
(appendix p 310) and compared them with WHO case
notication data to estimate under-reporting for cholera
and then the number of cases (appendix p 310). To
estimate cholera deaths, we modelled cholera case fatality
in DisMod-MR with data from previous studies.
Clostridium dicile as a cause of diarrhoea in children is
rarely studied; we could not estimate the epidemiological
population attributable fraction as we did for other
pathogens because C dicile was not included in GEMS.
Because C dicile is related to hospital and health-care
use, we used hospital data as the primary source for
estimation. We modelled the incidence and case fatality of
C dicile and assumed a 1-month risk of death60 in
DisMod-MR to estimate the number of deaths.
For GBD 2013, we split lower respiratory infection
mortality into four categories: Streptococcus pneumoniae,
Haemophilus inuenzae type B pneumonia, respiratory
syncytial virus pneumonia, and inuenza. The counterfactual approach captures the complex interactions
between the these causes61 and also excludes the other
lower respiratory infection category included in GBD
2010. Moreover, we did not attribute lower respiratory
infection to any cause for children younger than age
1 month. We adopted a dierent approach to estimate
bacterial and viral causes on the basis of available data.
For pneumococcal and H inuenzae type B pneumonia,
we estimated the causal fraction from vaccine ecacy
studies.6264 For pneumococcal pneumonia, we included
data from controlled trials and observational studies,
such as before-after population analyses of the
introduction of pneumococcal vaccine.6576 For
H inuenzae type B, we excluded case-control studies
because of implausibly large estimates of vaccine ecacy.
Furthermore, unlike for pneumococcal vaccine, little data
were available from vaccine ecacy studies on the eect
outside of child ages. As a result, we did not estimate the
causal fraction of H inuenzae type B for lower respiratory
infection in people aged 5 years or older. We adjusted data
for ecacy, using invasive disease as a marker as well as
serotype coverage for pneumococcal vaccine.64 We
calculated pooled estimates of causal fractions by age
with DisMod-MR for pneumococcal vaccine and
random-eects meta-analysis for H inuenzae type B,
adjusted post-hoc for national-level coverage of
pneumococcal vaccine and H inuenzae type B vaccine.
For respiratory syncytial virus and inuenza, we relied on
observational studies that measured causal fractions
among hospital admissions for lower respiratory
126
Convergence measures
To test whether all-cause and cause-specic mortality
converged in the 188 countries since 1990, we computed
two measures: the average relative dierence and the
average absolute dierence between any pair of countries
included in the GBD 2013 study. The average relative
dierence is known as the Gini coecient and is the most
commonly used measure of inequality. For international
comparisons, we used the population-weighted version of
the Gini coecient in age-specic mortality rates so that
small populations do not have an undue inuence on the
assessment of global mortality convergence (appendix
pp 556557).77 For the Gini coecient to fall, the percent
decrease in mortality for countries with higher mortality
must in general be faster than that for countries with
lower mortality.
We also computed the mean absolute dierence for
all-cause mortality for each age group for 19902013 and
for age-standardised rates for each cause (appendix
pp 556557). Average absolute dierence can fall while
average relative dierence (the Gini coecient) rises.
The two measures provide dierent perspectives on
convergence.
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Results
Global all-cause mortality
Global life expectancy at birth for both sexes increased
from 653 years in 1990, to 715 years in 2013, an
average increase of 027 years per calendar year. Life
expectancy increased over this period by 66 years for
females and 58 years for males. Figure 4 shows the
yearly change in global life expectancy at birth, with a
large drop in the 1990s as a result of the Rwanda
genocide and famine in North Korea and the return to
increases of about 03 years or more per year since
2003. If the median rate of change of the last 23 years
continues, by 2030 global female life expectancy will be
853 years and male life expectancy will be 781 years.
Reduced fertility and the consequent demographic
shift of the worlds population to older ages has led to
the mean age of death increasing from 467 years in
1990, to 593 years in 2013.81
The number of deaths globally for both sexes all ages
increased from 4747 (UI 46774822) million in 1990,
to 5486 (53575633) million in 2013, partly because of
consistent increases in global population over the past
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06
Change in life expectancy at birth (years)
05
04
03
02
01
0
Male
Female
Male (data from Rwanda and North Korea for 199395 excluded)
Female (data from Rwanda and North Korea for 199395 excluded)
01
02
03
1990
1995
2000
2005
2010
2013
Year
Figure 4: Change in global life expectancy at birth for males and females
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150
125
Deaths (millions)
100
75
50
25
0
04
59
1014
1519
2024
2529
3034
3539
4044
4549
5054
5559
6064
6569
7074
7579
80
Figure 5: Global deaths by age and super region in 1990 and 2013
older, both relative and absolute dierences in mean agespecic mortality rates have increased since 1990.
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015
Female
Male
3034
3539
2529
3034
3539
2529
010
14
14
<1
4044
4044
<1
2024
4549
7579
4549
7074
2024
7579
6569 50546569
5559
6064
7074
005
59
1014
5559
5054
59
1519
6064
80
80
1519
0
1014
60
50
40
30
20
10
Figure 6: Change in age-specic population-weighted Gini coecient versus relative change in mortality rate from 1990 to 2013
Solid points show age groups for which the mean absolute dierence between countries has increased and hollow points show those for which mean absolute
dierence has decreased.
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10
Years
Decreases
Increases
Figure 7: Change in life expectancy at birth by GBD region and cause group from 1990 to 2013
An interactive gure with these data is available at http://vizhub.healthdata.org/le. Changes in life expectancy as a result of specic causes were decomposed from
the dierence between all-cause lifetables and cause-deleted lifetables (mortality set to zero for a specic cause). Because all changes in life expectancy are based on
cross-sectional lifetables, the cause-specic changes add up to the total change in life-expectancy. NTDs=neglected tropical diseases.
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2013
Median % change
All causes
47 4687
54 8638
(46 7717 to 48 2233) (53 5761 to 56 3336)
156
(1254 to 1911)
11605
(11432 to 11790)
8797
(8599 to 9022)
242
(2620 to 2196)
16 1494
11 8096
(15 6745 to 16 5976) (11 3355 to 12 2830)
268
(2999 to 2410)
2895
(2812 to 2984)
1722
(1652 to 1788)
405
(4298 to 3835)
20725
(19382 to 22461)
26312
(24973 to 28632)
268
(1708 to 3792)
493
(462 to 533)
380
(360 to 416)
231
(2902 to 1639)
Tuberculosis
17861
(16664 to 19454)
12903
(11673 to 14062)
277
(3499 to 2056)
435
(404 to 472)
194
(176 to 212)
553
(5967 to 5101)
HIV/AIDS
2864
(2274 to 3703)
13410
(12578 to 14826)
3742
(26247 to 49073)
58
(46 to 76)
185
(174 to 205)
2220
(14514 to 30334)
840
(674 to 1049)
2051
(13068 to 29183)
06
(04 to 08)
12
(09 to 14)
1055
(5500 to 16622)
12570
(11781 to 13911)
3932
(2768651166)
53
(42 to 68)
174
(163 to 192)
2350
(15455 to 31943)
47505
(43888 to 50299)
394
(4517 to 3589)
1437
(1373 to 1519)
724
(667 to 765)
494
(5354 to 4675)
2586
(2061 to 3344)
2013
Median % change
Diarrhoeal diseases
25787
(24122 to 27489)
12641
(11512 to 13832)
510
(5555 to 4625)
474
(444 to 501)
190
(174 to 208)
598
(6354 to 5596)
2591
(1456 to 4246)
2213
(1226 to 3626)
143
(2608 to 275)
43
(24 to 70)
31
(17 to 50)
287
(3819 to 1898)
Typhoid fever
1805
(964 to 3023)
1607
(859 to 2680)
108
(2370 to 424)
30
(16 to 50)
22
(12 to 37)
259
(3631 to 1357)
Paratyphoid fever
634
(336 to 1067)
543
(293 to 920)
149
(3051 to 948)
10
(06 to 17)
07
(04 to 13)
280
(4099 to 797)
153
(135 to 173)
63
(55 to 70)
591
(6326 to 5409)
03
(02 to 03)
01
(01 to 01)
667
(7002 to 6284)
34207
(32116 to 36384)
26526
(23680 to 28081)
222
(2971 to 1632)
668
(631 to 716)
417
(371 to 441)
374
(4254 to 3345)
47
(40 to 56)
39
(33 to 47)
164
(3355 to 422)
01
(01 to 01)
01
(01 to 01)
408
(5240 to 2616)
Otitis media
49
(45 to 53)
24
(23 to 26)
508
(5422 to 4641)
01
(01 to 01)
00
(00 to 00)
608
(6334 to 5776)
Meningitis
4644
(4050 to 5590)
3035
(2614 to 3463)
343
(4534 to 2408)
77
(68 to 90)
43
(37 to 49)
439
(5265 to 3607)
Pneumococcal meningitis
1121
(977 to 1326)
791
(678 to 911)
294
(3984 to 1686)
19
(17 to 22)
11
(10 to 13)
417
(4960 to 3137)
1180
(982 to 1470)
644
(530 to 764)
454
(5479 to 3350)
18
(15 to 22)
09
(07 to 11)
497
(5821 to 3932)
Meningococcal meningitis
881
(761 to 1080)
657
(559 to 758)
249
(3882 to 1262)
15
(13 to 18)
09
(08 to 11)
373
(4755 to 2780)
Other meningitis
1461
(1280 to 1749)
942
(822 to 1064)
351
(4716 to 2471)
25
(22 to 29)
13
(12 to 15)
459
(5498 to 3748)
Encephalitis
922
(652 to 1162)
773
(654 to 970)
152
(4015 to 1601)
16
(11 to 19)
11
(09 to 14)
287
(4810 to 452)
Diphtheria
80
(39 to 188)
33
(17 to 66)
577
(8561 to 1254)
01
(01 to 03)
00
(00 to 01)
608
(8670 to 282)
Whooping cough
1382
(529 to 3002)
606
(223 to 1368)
567
(8376 to 1431)
19
(07 to 42)
08
(03 to 19)
582
(8431 to 1044)
Tetanus
3562
(2929 to 5786)
589
(398 to 773)
821
(9200 to 7610)
57
(47 to 91)
08
(06 to 11)
839
(9272 to 7784)
(Table 2 continues on next page)
Articles
1990
2013
Median % change
1990
2013
Median % change
Measles
5445
(3040 to 8678)
956
(485 to 1729)
830
(9023 to 6793)
78
(43 to 124)
13
(07 to 24)
837
(9066 to 6919)
Varicella
89
(72 to 117)
70
(57 to 87)
214
(4372 to 463)
02
(02 to 03)
01
(01 to 01)
456
(6128 to 2733)
1 0924
(9941 to 1 1967)
9970
(8405 to 1 1852)
92
(2509 to 1078)
185
(170 to 202)
139
(118 to 165)
249
(3719 to 970)
Malaria
8881
(7934 to 9927)
8546
(7029 to 1 0325)
44
(2361 to 1983)
146
(132 to 162)
119
(98 to 144)
189
(3432 to 018)
Chagas disease
127
(52 to 394)
106
(42 to 330)
193
(4112 to 2558)
03
(01 to 11)
02
(01 to 05)
517
(6606 to 2452)
Leishmaniasis
522
(446 to 606)
625
(523 to 733)
198
(356 to 3774)
09
(07 to 10)
09
(07 to 10)
03
(1418 to 1425)
522
(446 to 606)
625
(523 to 733)
198
(356 to 3774)
09
(07 to 10)
09
(07 to 10)
03
(1418 to 1425)
African trypanosomiasis
230
(114 to 377)
69
(37 to 109)
697
(7388 to 6494)
05
(02 to 07)
01
(01 to 01)
789
(8176 to 7554)
Schistosomiasis
174
(148 to 206)
55
(49 to 62)
682
(7356 to 6168)
04
(04 to 05)
01
(01 to 01)
807
(8406 to 7671)
Cysticercosis
09
(08 to 11)
07
(05 to 10)
286
(3523 to 1509)
00
(00 to 00)
00
(00 to 00)
530
(5759 to 4363)
Cystic echinococcosis
40
(38 to 43)
22
(21 to 24)
450
(4834 to 4122)
01
(01 to 01)
00
(00 to 00)
608
(6299 to 5826)
Dengue
88
(52 to 113)
91
(56 to 108)
13
(2169 to 7408)
01
(01 to 02)
01
(01 to 02)
136
(3142 to 4241)
Yellow fever
22
(19 to 25)
05
(04 to 06)
772
(8099 to 7234)
00
(00 to 00)
00
(00 to 00)
833
(8608 to 7971)
Rabies
384
(267 to 487)
235
(173 to 286)
383
(5314 to 2437)
07
(05 to 09)
03
(02 to 04)
540
(6409 to 4423)
91
(81 to 102)
45
(40 to 51)
507
(5628 to 4347)
01
(01 to 02)
01
(01 to 01)
547
(5966 to 4846)
91
(81 to 102)
45
(40 to 51)
507
(5628 to 4347)
01
(01 to 02)
01
(01 to 01)
547
(5966 to 4846)
356
(264 to 442)
163
(139 to 196)
544
(6457 to 3637)
06
(05 to 08)
02
(02 to 03)
623
(6958 to 4975)
3766
(3440 to 4082)
2933
(2613 to 3282)
223
(3163 to 1138)
69
(63 to 75)
39
(35 to 44)
436
(5045 to 3570)
Maternal haemorrhage
714
(646 to 785)
442
(383 to 510)
381
(4724 to 2703)
13
(12 to 14)
06
(05 to 07)
550
(6151 to 4697)
341
(305 to 380)
238
(201 to 280)
304
(4243 to 1510)
06
(06 to 07)
03
(03 to 04)
500
(5840 to 3900)
366
(333 to 399)
293
(257 to 335)
200
(3089 to 722)
07
(06 to 07)
04
(03 to 04)
413
(4914 to 3220)
Obstructed labour
293
(263 to 327)
188
(163 to 218)
359
(4556 to 2386)
05
(05 to 06)
02
(02 to 03)
534
(6020 to 4445)
Complications of abortion
500
(458 to 548)
437
(383 to 499)
126
(2472 to 200)
09
(09 to 10)
06
(05 to 07)
375
(4615 to 2671)
401
(355 to 444)
311
(268 to 358)
227
(3425 to 762)
07
(06 to 08)
04
(04 to 05)
434
(5181 to 3238)
449
(364 to 532)
435
(357 to 524)
18
(2681 to 2195)
08
(07 to 10)
06
(05 to 07)
284
(4661 to 1167)
08
(05 to 11)
21
(13 to 29)
1617
(12802 to 20266)
00
(00 to 00)
00
(00 to 00)
941
(6926 to 12447)
686
(584 to 804)
562
(487 to 644)
182
(3179 to 004)
13
(11 to 15)
07
(06 to 09)
408
(5036 to 2788)
Visceral leishmaniasis
Ascariasis
Other neglected tropical diseases
Maternal disorders
132
Articles
1990
2013
Median % change
1990
2013
Median % change
3 4333
(3 2257 to 3 5861)
2 0480
(1 9347 to 2 1603)
403
(4396 to 3630)
469
(441 to 490)
276
(261 to 291)
411
(4471 to 3713)
1 5705
(1 2850 to 1 8035)
7424
(5913 to 9108)
529
(5870 to 4550)
214
(175 to 246)
100
(80 to 123)
535
(5923 to 4620)
8741
(6885 to 1 0554)
6438
(5150 to 7605)
261
(3829 to 1135)
119
(94 to 144)
87
(69 to 103)
271
(3906 to 1249)
3464
(1957 to 4840)
3660
(2332 to 5108)
61
(1594 to 3804)
47
(27 to 66)
49
(31 to 69)
46
(1713 to 3599)
196
(130 to 297)
700
(7978 to 5043)
09
(05 to 13)
03
(02 to 04)
706
(8017 to 5117)
5776
(4575 to 7560)
2762
(2196 to 3507)
523
(6241 to 3677)
79
(63 to 103)
37
(30 to 47)
530
(6301 to 3768)
7577
(6415 to 9344)
6811
(5335 to 7955)
97
(2287 to 186)
147
(124 to 182)
104
(82 to 122)
286
(3877 to 2045)
Protein-energy malnutrition
5079
(3943 to 6485)
4688
(3500 to 5609)
73
(2292 to 751)
92
(71 to 118)
71
(53 to 85)
225
(3454 to 1134)
Iodine deciency
21
(14 to 34)
27
(15 to 47)
245
(2982 to 13721)
00
(00 to 01)
00
(00 to 01)
79
(4713 to 8062)
Iron-deciency anemia
2134
(1435 to 3093)
1834
(1220 to 2592)
138
(3236 to 533)
46
(33 to 66)
28
(19 to 40)
388
(5036 to 2657)
343
(238 to 561)
262
(170 to 412)
225
(4266 to 464)
08
(05 to 13)
04
(03 to 07)
454
(5640 to 3385)
5365
(4330 to 6749)
4084
(3421 to 4883)
238
(3394 to 1153)
94
(79 to 114)
59
(50 to 70)
374
(4455 to 2828)
2576
(1547 to 3964)
1420
(876 to 2139)
445
(5596 to 3277)
38
(24 to 57)
19
(12 to 29)
484
(5854 to 3736)
Syphilis
2506
(1474 to 3891)
1368
(824 to 2089)
451
(5656 to 3302)
36
(22 to 55)
19
(11 to 29)
480
(5861 to 3683)
Chlamydial infection
15
(11 to 19)
11
(09 to 14)
230
(4259 to 003)
00
(00 to 00)
00
(00 to 00)
511
(6466 to 3462)
Gonococcal infection
32
(25 to 38)
23
(20 to 29)
266
(4191 to 675)
01
(01 to 01)
00
(00 to 00)
540
(6457 to 3974)
24
(19 to 28)
17
(15 to 21)
273
(4208 to 1071)
01
(00 to 01)
00
(00 to 00)
532
(6349 to 4060)
1620
(1528 to 1714)
1367
(1237 to 1632)
168
(2524 to 296)
33
(31 to 35)
20
(18 to 24)
396
(4537 to 2580)
Hepatitis A
226
(79 to 402)
149
(50 to 277)
363
(5041 to 245)
03
(01 to 06)
02
(01 to 04)
419
(5439 to 1204)
Hepatitis B
850
(651 to 1040)
686
(520 to 866)
197
(2894 to 423)
19
(15 to 22)
11
(08 to 13)
446
(5038 to 3537)
Hepatitis C
23
(05 to 53)
35
(07 to 82)
510
(2440 to 8656)
01
(00 to 01)
01
(00 to 01)
42
(2086 to 1767)
Hepatitis E
521
(390 to 672)
497
(361 to 675)
61
(1783 to 2041)
10
(07 to 13)
07
(05 to 10)
308
(3935 to 1137)
1169
(940 to 1443)
1298
(896 to 1649)
113
(2167 to 4500)
24
(19 to 30)
20
(14 to 25)
177
(4292 to 731)
26 9935
(26 2981 to
27 6391)
38 2672
(37 2022 to 39 4176)
417
(3686 to 4700)
7825
(7655 to 7982)
6375
(6204 to 6557)
186
(2108 to 1578)
56597
(54404 to 58266)
82357
(79414 to 85389)
456
(3982 to 5155)
1570
(1513 to 1615)
1338
(1289 to 1386)
147
(1791 to 1149)
Oesophageal cancer
3131
(2750 to 3515)
4402
(3892 to 5168)
399
(2642 to 5636)
88
(78 to 99)
72
(63 to 84)
193
(2713 to 994)
Stomach cancer
7634
(7256 to 8032)
8410
(7916 to 8941)
101
(394 to 1743)
217
(206 to 229)
138
(130 to 147)
363
(3982 to 3214)
Nutritional deciencies
Hepatitis
Neoplasms
133
Articles
1990
2013
Median % change
1990
2013
Median % change
5101
(4749 to 5431)
8180
(7637 to 8790)
603
(4621 to 7528)
137
(127 to 145)
130
(121 to 139)
50
(1301 to 361)
1984
(1817 to 2154)
3000
(2720 to 3292)
516
(3351 to 7202)
51
(47 to 55)
46
(42 to 51)
91
(1963 to 269)
874
(795 to 947)
3425
(3171 to 3753)
2908 (25146 to
34252)
24
(22 to 26)
55
(51 to 60)
1254
(10382 to 15485)
1228
(1138 to 1325)
922
(848 to 1003)
252 (3120 to
1709)
35
(32 to 37)
15
(14 to 16)
564
(5987 to 5182)
1015
(928 to 1100)
833
(751 to 922)
175
(2857 to 702)
26
(24 to 29)
13
(12 to 14)
505
(5697 to 4423)
Larynx cancer
762
(627 to 881)
876
(743 to 1062)
142
(725 to 2755)
21
(17 to 24)
14
(12 to 17)
334
(3726 to 2629)
10500
(10106 to 10782)
16396
(15656 to 17060)
565
(4783 to 6284)
296
(285 to 304)
270
(257 to 281)
87
(1362 to 516)
Breast cancer
3273
(2892 to 3668)
4710
(4120 to 5142)
442
(3501 to 5182)
90
(79 to 101)
74
(64 to 81)
175
(2342 to 1338)
Cervical cancer
1963
(1629 to 2124)
2357
(2019 to 2579)
201
(1074 to 3015)
52
(43 to 56)
36
(31 to 40)
301
(3555 to 2413)
Uterine cancer
456
(366 to 556)
677
(536 to 790)
486
(3064 to 6439)
13
(10 to 16)
11
(09 to 13)
150
(2461 to 658)
Prostate cancer
1571
(1240 to 1931)
2927
(2422 to 3739)
828
(7177 to 10902)
51
(40 to 63)
52
(43 to 66)
10
(717 to 1305)
4902
(4761 to 5045)
7711
(7415 to 7992)
574
(5189 to 6264)
145
(141 to 149)
128
(124 to 133)
111
(1440 to 817)
839
(740 to 962)
1350
(1153 to 1543)
597
(4691 to 7839)
23
(20 to 26)
21
(18 to 25)
79
(1496 to 232)
Nasopharynx cancer
537
(477 to 635)
605
(540 to 695)
127
(119 to 2474)
14
(12 to 16)
09
(08 to 11)
325
(3931 to 2555)
489
(437 to 535)
786
(670 to 863)
609
(4326 to 7641)
13
(12 to 14)
12
(10 to 13)
71
(1697 to 204)
1154
(1006 to 1304)
1395
(1200 to 1550)
221
(685 to 3236)
34
(30 to 39)
23
(20 to 26)
312
(3996 to 2522)
Pancreatic cancer
1864
(1813 to 1918)
3524
(3394 to 3648)
890
(8243 to 9546)
54
(53 to 56)
59
(56 to 61)
74
(363 to 1104)
387
(301 to 509)
569
(439 to 757)
476
(3154 to 5781)
11
(08 to 14)
09
(07 to 12)
141
(2386 to 806)
250
(202 to 300)
392
(328 to 487)
550
(4330 to 7659)
08
(06 to 09)
07
(06 to 08)
129
(2000 to 093)
Ovarian cancer
989
(931 to 1061)
1578
(1475 to 1695)
596
(5081 to 6888)
27
(26 to 29)
25
(23 to 27)
78
(1297 to 256)
Testicular cancer
70
(54 to 82)
83
(63 to 104)
184
(886 to 3542)
02
(01 to 02)
01
(01 to 01)
230
(2860 to 1108)
Kidney cancer
779
(738 to 830)
1338
(1260 to 1411)
718
(6306 to 8102)
21
(20 to 23)
22
(20 to 23)
16
(395 to 811)
Bladder cancer
1308
(1166 to 1409)
1739
(1568 to 1925)
322
(2735 to 4306)
40
(35 to 43)
30
(27 to 33)
256
(2836 to 2014)
1360
(1166 to 1552)
2039
(1695 to 2348)
504
(3404 to 6033)
33
(28 to 38)
31
(26 to 36)
46
(1399 to 096)
Thyroid cancer
238
(203 to 261)
337
(296 to 382)
411
(2980 to 5927)
07
(06 to 08)
06
(05 to 06)
196
(2550 to 909)
Mesothelioma
170
(152 to 203)
337
(294 to 387)
1005
(6994 to 11547)
05
(04 to 06)
05
(05 to 06)
162
(242 to 2492)
Hodgkin lymphoma
336
(241 to 380)
242
(220 to 316)
330
(4041 to 1535)
08
(05 to 08)
04
(03 to 05)
549
(5893 to 2434)
Non-Hodgkin lymphoma
1336
(1163 to 1580)
2255
(1863 to 2458)
720
(4151 to 8435)
35
(31 to 42)
36
(29 to 39)
61
(1456 to 1342)
Multiple myeloma
453
(374 to 574)
794
(653 to 942)
771
(5364 to 9008)
13
(11 to 17)
13
(11 to 16)
04
(1332 to 827)
134
Articles
1990
2013
Median % change
1990
2013
Median % change
Leukaemia
2238
(2151 to 2342)
2651
(2539 to 2758)
187
(1169 to 2419)
52
(50 to 54)
41
(39 to 43)
200
(2412 to 1668)
Other neoplasms
2506
(2318 to 3052)
3696
(3280 to 4001)
513
(1557 to 6210)
62
(58 to 73)
58
(52 to 63)
42
(2344 to 332)
12 2796
17 2975
(11 7766 to 12 7641) (16 5202 to 18 0719)
408
(3617 to 4636)
3755
(3605 to 3891)
2932
(2804 to 3061)
220
(2450 to 1907)
3735
(3025 to 4646)
2751
(2226 to 3539)
265
(3364 to 1720)
98
(79 to 122)
44
(35 to 56)
554
(5947 to 5011)
57375
(52549 to 61486)
81399
(73229 to 87585)
417
(3596 to 4844)
1773
(1618 to 1902)
1378
(1239 to 1482)
223
(2548 to 1868)
Cerebrovascular disease
45848
(41621 to 49681)
64469
(59630 to 71552)
402
(3443 to 4956)
1416
(1285 to 1539)
1101
(1018 to 1222)
225
(2556 to 1730)
Ischaemic stroke
21 829
(19233 to 24309)
32729
(28127 to 35926)
502
(4102 to 5927)
713
(630 to 793)
573
(493 to 629)
196
(2452 to 1497)
Haemorrhagic stroke
24019
(21094 to 26691)
31740
(28857 to 37197)
307
(2223 to 4907)
703
(612 to 779)
528
(480 to 623)
259
(3064 to 1473)
6221
(5257 to 7839)
10686
(8498 to 1 2422)
741
(4734 to 9373)
193
(164 to 244)
182
(145 to 213)
45
(1886 to 641)
2939
(2435 to 3463)
4433
(3701 to 5120)
514
(3727 to 6145)
82
(69 to 96)
71
(60 to 83)
126
(1998 to 768)
289
(260 to 324)
1122
(977 to 1267)
2881
(24632 to 33503)
10
(09 to 11)
20
(18 to 23)
1000
(7755 to 12490)
Aortic aneurysm
996
(824 to 1185)
1515
(1242 to 1800)
521
(4375 to 6091)
30
(25 to 36)
26
(21 to 31)
153
(2006 to 1050)
159
(144 to 175)
405
(355 to 449)
1553
(12651 to 17839)
05
(05 to 06)
07
(06 to 08)
341
(1877 to 4662)
Endocarditis
451
(356 to 586)
650
(486 to 794)
463
(2388 to 6552)
12
(10 to 16)
10
(08 to 13)
127
(2581 to 280)
4783
(4039 to 5464)
5546
(4991 to 6542)
152
(938 to 3252)
136
(115 to 155)
93
(83 to 108)
322
(3544 to 2240)
34902
(32804 to 37953)
42675
(39963 to 46942)
219
(1495 to 3148)
1045
(985 to 1133)
730
(684 to 802)
304
(3419 to 2505)
24213
(21513 to 26324)
29312
(26263 to 32158)
210
(1270 to 3126)
748
(668 to 812)
507
(454 to 556)
323
(3675 to 2654)
Pneumoconiosis
2512
(1840 to 3178)
2597
(2017 to 3312)
19
(1521 to 4027)
72
(53 to 90)
43
(33 to 55)
405
(5081 to 1984)
Silicosis
554
(367 to 771)
463
(321 to 648)
160
(3285 to 614)
16
(10 to 22)
08
(05 to 11)
507
(6118 to 3806)
Asbestosis
210
(139 to 304)
241
(175 to 323)
142
(1020 to 5487)
06
(04 to 09)
04
(03 to 05)
326
(4735 to 961)
289
(182 to 439)
252
(190 to 356)
137
(3065 to 2306)
08
(05 to 12)
04
(03 to 06)
502
(6026 to 2913)
Other pneumoconiosis
1459
(1003 to 1892)
1641
(1231 to 2136)
109
(1348 to 6123)
42
(29 to 55)
27
(20 to 36)
353
(5019 to 677)
5043
(3997 to 7318)
4890
(3977 to 6768)
29
(2458 to 1921)
137
(108 to 204)
80
(65 to 111)
415
(5517 to 2801)
4715
(3723 to 6068)
1141
(5325 to 21486)
66
(39 to 89)
80
(63 to 103)
201
(1189 to 7420)
958
(783 to 1138)
1161
(992 to 1369)
212
(778 to 4066)
22
(18 to 27)
19
(16 to 23)
151
(2422 to 339)
8380
(8070 to 8667)
1 2211
(1 1703 to 1 2843)
456
(3847 to 5452)
218
(209 to 225)
188
(180 to 197)
137
(1775 to 849)
2339
(2208 to 2500)
3174
(2923 to 3446)
356
(2266 to 4958)
61
(57 to 65)
49
(45 to 53)
193
(2686 to 1111)
2131
(2004 to 2267)
3578
(3343 to 3861)
673
(5460 to 8386)
57
(54 to 60)
56
(52 to 60)
24
(958 to 748)
2922
(2765 to 3071)
3838
(3562 to 4147)
312
(2027 to 4397)
78
(74 to 82)
59
(55 to 64)
241
(3024 to 1692)
Cardiovascular diseases
Asthma
135
Articles
1990
2013
Median % change
1990
2013
Median % change
988
(921 to 1060)
1621
(1455 to 1829)
635
(4765 to 8621)
22
(20 to 23)
24
(21 to 27)
93
(152 to 2419)
10532
(9586 to 1 1312)
11683
(1 0644 to 1 2755)
104
(211 to 2238)
284
(258 to 305)
190
(174 to 207)
335
(3830 to 2651)
3269
(2888 to 3887)
3014
(2498 to 3505)
76
(2126 to 552)
91
(80 to 107)
49
(41 to 57)
458
(5337 to 3853)
542
(321 to 763)
595
(422 to 901)
58
(1346 to 5038)
14
(08 to 20)
10
(07 to 15)
351
(4654 to 686)
Appendicitis
875
(708 to 1059)
719
(514 to 895)
178
(3466 to 268)
20
(16 to 24)
11
(08 to 14)
457
(5637 to 3327)
1780
(1163 to 2285)
2357
(1756 to 3270)
294
(1132 to 6861)
47
(31 to 61)
38
(28 to 53)
203
(3107 to 180)
505
(332 to 612)
325
(256 to 488)
418
(4926 to 488)
14
(09 to 17)
05
(04 to 08)
648
(6929 to 4412)
549
(404 to 672)
512
(424 to 697)
87
(1741 to 1301)
14
(10 to 16)
08
(07 to 11)
418
(4730 to 2530)
526
(347 to 784)
795
(519 to 1133)
518
(3603 to 6716)
16
(11 to 24)
14
(09 to 19)
163
(2449 to 810)
805
(689 to 941)
1059
(891 to 1223)
322
(1876 to 4346)
24
(20 to 28)
18
(15 to 21)
245
(3176 to 1821)
Pancreatitis
830
(592 to 1113)
1226
(859 to 1523)
491
(1602 to 7694)
21
(15 to 29)
19
(13 to 24)
102
(2933 to 574)
852
(733 to 995)
1080
(904 to 1242)
271
(1425 to 3904)
23
(20 to 26)
18
(15 to 20)
219
(2904 to 1513)
10175
(9650 to 1 0723)
19768
(18750 to 20807)
940
(8399 to 10661)
342
(323 to 361)
350
(332 to 369)
23
(327 to 908)
7958
(7479 to 8443)
16551
(15635 to 17653)
1072
(9494 to 12400)
289
(271 to 307)
299
(282 to 319)
32
(301 to 1161)
Parkinsons disease
437
(383 to 551)
1025
(793 to 1126)
1398
(7736 to 15699)
15
(13 to 19)
18
(14 to 20)
282
(642 to 3783)
Epilepsy
1110
(955 to 1299)
1158
(937 to 1320)
47
(1205 to 2400)
22
(19 to 25)
17
(13 to 19)
224
(3373 to 1021)
Multiple sclerosis
124
(92 to 190)
198
(128 to 255)
648
(360 to 8709)
03
(02 to 05)
03
(02 to 04)
11
(3878 to 1191)
546
(471 to 608)
837
(718 to 908)
542
(3788 to 6072)
14
(12 to 15)
13
(11 to 14)
36
(1027 to 043)
1883
(1572 to 2423)
2824
(2339 to 3293)
515
(3226 to 6384)
43
(36 to 57)
40
(33 to 47)
57
(1855 to 210)
Schizophrenia
228
(147 to 283)
160
(137 to 228)
355
(4652 to 2994)
06
(04 to 07)
02
(02 to 03)
597
(6647 to 2007)
1119
(840 to 1653)
1392
(902 to 1785)
282
(178 to 3566)
27
(20 to 39)
20
(13 to 26)
220
(3853 to 1754)
532
(478 to 641)
1266
(1108 to 1355)
1404
(10160 to 15988)
11
(10 to 13)
18
(16 to 19)
630
(3610 to 7481)
180
(165 to 222)
507
(434 to 544)
1873
(13480 to 21024)
04
(03 to 05)
07
(06 to 08)
927
(5669 to 10716)
24
(22 to 29)
43
(39 to 47)
772
(4911 to 10226)
01
(00 to 01)
01
(01 to 01)
209
(197 to 3634)
21
(19 to 25)
38
(34 to 41)
804
(5249 to 10670)
00
(00 to 01)
01
(00 to 01)
232
(470 to 4049)
307
(261 to 373)
677
(595 to 728)
1228
(8651 to 14632)
06
(06 to 08)
10
(08 to 10)
516
(2634 to 6539)
04
(03 to 04)
06
(05 to 07)
604
(4117 to 8468)
00
(00 to 00)
00
(00 to 00)
135
(042 to 3016)
04
(03 to 04)
06
(05 to 07)
604
(4117 to 8468)
00
(00 to 00)
00
(00 to 00)
135
(042 to 3016)
Neurological disorders
Eating disorders
Anorexia nervosa
136
Articles
1990
2013
Median % change
1990
2013
Median % change
15694
(14567 to 17092)
29550
(27640 to 31711)
889
(7644 to 9949)
422
(395 to 447)
483
(451 to 514)
144
(953 to 2014)
Diabetes mellitus
6843
(6532 to 7115)
12994
(12345 to 13748)
897
(8177 to 9994)
198
(189 to 206)
216
(206 to 229)
90
(459 to 1469)
Acute glomerulonephritis
236
(137 to 334)
188
(143 to 228)
214
(3696 to 1496)
05
(03 to 08)
03
(02 to 03)
458
(5570 to 2157)
4086
(3638 to 4334)
9562
(8129 to 1 0345)
1346
(11570 to 15020)
116
(104 to 123)
158
(135 to 171)
369
(2543 to 4611)
463
(348 to 548)
1731
(1393 to 2088)
2741
(24306 to 30905)
14
(10 to 16)
29
(23 to 35)
1065
(8967 to 12774)
1200
(916 to 1448)
2757
(1969 to 3365)
1306
(10628 to 15138)
36
(28 to 44)
46
(33 to 56)
294
(1520 to 4043)
990
(845 to 1147)
1163
(929 to 1440)
169
(169 to 3532)
25
(21 to 29)
18
(15 to 23)
268
(3584 to 1566)
3912
(2970 to 4523)
1753
(14005 to 20216)
41
(33 to 48)
65
(49 to 75)
588
(3759 to 7471)
2458
(2055 to 2647)
628
(4974 to 7237)
43
(37 to 46)
41
(34 to 44)
37
(1286 to 166)
1099
Interstitial nephritis and urinary tract
infections
(929 to 1181)
1755
(1446 to 1920)
589
(4857 to 7408)
31
(27 to 34)
29
(24 to 32)
63
(1436 to 219)
Urolithiasis
151
(111 to 187)
147
(124 to 201)
59
(1602 to 4487)
04
(03 to 05)
02
(02 to 03)
453
(5097 to 1432)
263
(219 to 350)
555
(404 to 665)
1224
(6954 to 15157)
07
(06 to 10)
09
(07 to 11)
325
(275 to 5004)
53
(39 to 70)
34
(29 to 48)
367
(4776 to 1433)
01
(01 to 02)
01
(00 to 01)
595
(6715 to 4556)
Uterine broids
12
(09 to 17)
09
(07 to 12)
297
(4396 to 620)
00
(00 to 00)
00
(00 to 00)
578
(6654 to 4372)
02
(01 to 03)
01
(01 to 02)
562
(6348 to 2990)
00
(00 to 00)
00
(00 to 00)
685
(7381 to 4956)
Endometriosis
05
(04 to 06)
02
(02 to 04)
547
(6211 to 2937)
00
(00 to 00)
00
(00 to 00)
689
(7405 to 5125)
Genital prolapse
09
(07 to 12)
06
(05 to 09)
299
(4402 to 828)
00
(00 to 00)
00
(00 to 00)
557
(6545 to 4231)
25
(18 to 32)
16
(13 to 22)
374
(4819 to 1538)
01
(00 to 01)
00
(00 to 00)
597
(6723 to 4618)
2404
(1060 to 4561)
206
(135 to 9291)
31
(16 to 50)
34
(15 to 63)
04
(1905 to 5195)
Gynaecological diseases
1514
(1291 to 1611)
362
(212 to 494)
248
(169 to 321)
364
(4690 to 1405)
06
(03 to 08)
03
(02 to 04)
437
(5263 to 283)
1129
(394 to 2226)
1762
(563 to 3857)
453
(1430 to 13119)
18
(06 to 34)
24
(08 to 53)
288
(153 to 9435)
G6PD deciency
34
(20 to 46)
41
(26 to 56)
127
(712 to 9190)
01
(00 to 01)
01
(00 to 01)
82
(2319 to 4512)
303
(198 to 386)
354
(243 to 449)
151
(342 to 4666)
08
(05 to 10)
06
(04 to 07)
258
(3166 to 980)
1135
(906 to 1344)
1910
(1505 to 2185)
695
(4911 to 8562)
27
(22 to 32)
30
(24 to 34)
116
(055 to 2087)
659
(550 to 734)
1163
(1004 to 1377)
771
(5442 to 10522)
17
(15 to 19)
19
(16 to 22)
85
(462 to 2348)
Rheumatoid arthritis
278
(238 to 317)
381
(330 to 469)
356
(1643 to 6474)
08
(07 to 09)
06
(05 to 08)
205
(3122 to 453)
381
(303 to 441)
782
(652 to 903)
1072
(7694 to 14559)
09
(08 to 11)
12
(10 to 14)
327
(1417 to 5137)
8317
(6907 to 1 0610)
7466
(6741 to 8462)
76
(2531 to 405)
129
(109 to 161)
105
(95 to 119)
164
(3083 to 720)
137
Articles
1990
2013
Median % change
1990
2013
Median % change
Congenital anomalies
7506
(6118 to 9697)
6321
(5613 to 7303)
135
(3040 to 080)
110
(90 to 141)
87
(77 to 100)
189
(3407 to 754)
1513
(1091 to 2563)
689
(409 to 1244)
548
(6535 to 4239)
21
(15 to 36)
09
(06 to 17)
566
(6671 to 4461)
3662
(2930 to 4852)
3234
(2883 to 3726)
98
(2983 to 737)
54
(44 to 70)
45
(40 to 51)
158
(3364 to 061)
Orofacial clefts
76
(42 to 115)
33
(19 to 52)
578
(6883 to 3393)
01
(01 to 02)
00
(00 to 01)
585
(6940 to 3504)
Downs syndrome
425
(164 to 730)
364
(204 to 524)
129
(3913 to 4014)
07
(03 to 11)
05
(03 to 07)
226
(4511 to 1989)
Chromosomal unbalanced
rearrangements
191
(85 to 412)
173
(106 to 268)
55
(4018 to 3589)
03
(01 to 06)
02
(01 to 04)
30
(4313 to 2513)
1639
(1199 to 3019)
1828
(1502 to 2619)
180
(1645 to 4074)
24
(18 to 44)
25
(21 to 36)
85
(2090 to 2930)
591
(541 to 631)
994
(899 to 1073)
683
(5136 to 8644)
16
(15 to 17)
16
(15 to 18)
25
(766 to 1083)
Cellulitis
270
(190 to 341)
295
(225 to 393)
80
(523 to 3003)
07
(05 to 08)
05
(04 to 06)
298
(3847 to 1625)
Pyoderma
167
(116 to 231)
377
(302 to 429)
1299
(7183 to 18699)
04
(03 to 06)
06
(05 to 07)
440
(1402 to 7543)
Decubitus ulcer
137
(115 to 169)
285
(244 to 330)
1096
(8253 to 13242)
05
(04 to 06)
05
(04 to 06)
83
(481 to 1909)
17
(12 to 22)
38
(30 to 49)
1384
(7418 to 20177)
00
(00 to 01)
01
(00 to 01)
359
(437 to 6936)
220
(127 to 402)
151
(96 to 214)
295
(5451 to 422)
03
(02 to 06)
02
(01 to 03)
310
(5552 to 634)
43258
(40957 to 45240)
47869
(45079 to 50728)
104
(423 to 1804)
885
(845 to 930)
700
(659 to 742)
210
(2527 to 1585)
Transport injuries
11500
(10929 to 12539)
14827
(13648 to 15888)
293
(1711 to 3866)
232
(221 to 251)
212
(195 to 227)
84
(1654 to 202)
Road injuries
10584
(10050 to 11672)
13958
(12861 to 14927)
324
(1921 to 4184)
213
(203 to 234)
200
(184 to 213)
61
(1512 to 028)
3897
(3396 to 4720)
5438
(4520 to 6291)
402
(1755 to 5863)
80
(70 to 96)
80
(67 to 92)
01
(1584 to 1251)
686
(585 to 833)
906
(742 to 1066)
320
(1351 to 5106)
14
(12 to 17)
13
(11 to 16)
75
(2014 to 551)
2020
(1693 to 2364)
2485
(2009 to 2944)
228
(772 to 4045)
39
(32 to 45)
34
(28 to 40)
122
(2277 to 056)
3644
(3244 to 4091)
4927
(4310 to 5551)
355
(2424 to 4649)
73
(65 to 82)
69
(61 to 78)
49
(1290 to 269)
338
(219 to 441)
202
(144 to 255)
407
(5401 to 744)
07
(04 to 09)
03
(02 to 04)
573
(6723 to 3433)
916
(774 to 1020)
869
(720 to 972)
53
(1827 to 1072)
19
(16 to 21)
12
(10 to 14)
336
(4261 to 2272)
20172
(18486 to 2 1657)
20067
(18571 to 2 1831)
10
(896 to 1095)
408
(382 to 438)
304
(280 to 329)
257
(3189 to 1823)
Falls
3405
(3117 to 4115)
5564
(4485 to 6107)
667
(2125 to 8298)
90
(82 to 108)
91
(73 to 99)
34
(2397 to 1161)
Drowning
5449
(4092 to 6358)
3681
(3110 to 5154)
350
(4335 to 1798)
94
(72 to 108)
52
(44 to 73)
463
(5233 to 600)
2996
(2627 to 3529)
2375
(1993 to 2829)
212
(3396 to 198)
59
(52 to 70)
35
(29 to 41)
419
(5085 to 2974)
Poisonings
1202
(1041 to 1685)
980
(702 to 1108)
127
(4483 to 008)
24
(21 to 33)
14
(10 to 16)
360
(5897 to 2757)
2327
(1863 to 2739)
1968
(1779 to 2446)
156
(3165 to 1868)
41
(34 to 48)
28
(25 to 35)
326
(4348 to 905)
138
Articles
1990
2013
Median % change
1990
2013
Median % change
514
(445 to 600)
473
(410 to 557)
76
(2630 to 1315)
10
(09 to 12)
07
(06 to 08)
328
(4694 to 1802)
Unintentional suocation
840
(269 to 1246)
376
(291 to 807)
583
(7465 to 9029)
12
(04 to 18)
05
(04 to 11)
597
(7513 to 7119)
972
(888 to 1199)
1119
(955 to 1224)
166
(1364 to 3093)
19
(17 to 23)
16
(14 to 17)
147
(3650 to 526)
935
(772 to 1102)
1417
(1075 to 1659)
532
(2788 to 7338)
21
(18 to 26)
22
(17 to 26)
46
(1130 to 1634)
Animal contact
955
(598 to 1266)
796
(623 to 1387)
220
(3547 to 3457)
19
(12 to 25)
12
(09 to 20)
430
(5223 to 249)
763
(475 to 1047)
572
(441 to 1025)
301
(4314 to 2805)
15
(09 to 20)
08
(06 to 15)
493
(5849 to 680)
192
(115 to 263)
224
(164 to 368)
112
(933 to 7385)
04
(02 to 05)
03
(02 to 06)
169
(3127 to 2518)
1422
(995 to 2116)
1657
(1148 to 2191)
162
(1022 to 4591)
29
(21 to 43)
26
(18 to 34)
102
(2981 to 596)
1398
(972 to 2097)
1621
(1098 to 2147)
155
(1110 to 4578)
29
(20 to 42)
25
(17 to 34)
106
(3035 to 587)
25
(16 to 35)
36
(27 to 54)
515
(311 to 8433)
01
(00 to 01)
01
(00 to 01)
68
(2559 to 3138)
1481
(1199 to 1628)
1628
(1439 to 1803)
93
(423 to 3311)
31
(25 to 34)
24
(21 to 27)
211
(3053 to 499)
10528
(9293 to 11520)
12471
(10672 to 13909)
182
(838 to 2900)
224
(198 to 246)
178
(153 to 198)
208
(2732 to 1383)
Self-harm
7120
(6306 to 7847)
8424
(7181 to 9390)
178
(604 to 3220)
158
(139 to 173)
122
(104 to 136)
231
(3045 to 1397)
Interpersonal violence
3407
(2539 to 4151)
4047
(2987 to 4966)
184
(1024 to 2934)
66
(49 to 81)
56
(41 to 69)
160
(2165 to 841)
Assault by rearm
1276
(899 to 1651)
1804
(1205 to 2313)
413
(2605 to 5553)
25
(17 to 32)
25
(16 to 32)
00
(1058 to 1011)
940
(651 to 1278)
1143
(771 to 1632)
210
(627 to 4068)
18
(13 to 25)
16
(11 to 22)
152
(2563 to 129)
1191
(844 to 1429)
1100
(787 to 1421)
85
(1648 to 797)
23
(16 to 28)
15
(11 to 20)
339
(3944 to 2231)
1058
(772 to 1707)
504
(344 to 888)
531
(5841 to 4615)
22
(15 to 36)
07
(05 to 13)
662
(7018 to 6118)
334
(194 to 635)
192
(135 to 320)
439
(5870 to 692)
07
(04 to 14)
03
(02 to 05)
604
(7150 to 3398)
724
(547 to 1065)
312
(203 to 570)
579
(6676 to 4585)
15
(11 to 22)
05
(03 to 08)
693
(7576 to 6123)
Foreign body
Table 2: Global deaths for 235 causes in 1990 and 2013 for all ages and both sexes combined and age-standardised death rates
Articles
1990 (thousands)
2013 (thousands)
Median % change
1990 (thousands)
2013 (thousands)
Median % change
All causes
45068
(43945 to
46128)
26143
(25064 to
27232)
420
(445 to 395)
76085
(74477 to 77573)
36657
(34494 to
39058)
520
(547 to 486)
Communicable, maternal,
neonatal, and nutritional
diseases
40638
22755
(39350 to 41814) (21636 to
23746)
440
(466 to 414)
60126
27662
540
(57240 to 62565) (25286 to 30105) (575 to 504)
HIV/AIDS
Diarrhoeal diseases
Intestinal infectious diseases
1248
(1105 to 1405)
448
(368 to 533)
642
(706 to 567)
352
(323 to 383)
638
(585 to 716)
811
(645 to 999)
14824
(13397 to 16333)
4749
(3981 to 5450)
680
(728 to 625)
820
(467 to 1352)
624
(330 to 1036)
242
(372 to 81)
3993
(3622 to 4369)
1965
(1693 to 2245)
509
(573 to 437)
17688
(15977 to 19266)
7086
(6286 to 7914)
599
(648 to 545)
Meningitis
356
(277 to 470)
206
(149 to 268)
426
(527 to 284)
2625
(2121 to 3463)
1214
(902 to 1570)
540
(634 to 415)
1298
(499 to 2807)
564
(207 to 1270)
571
(839 to 127)
654
(482 to 1216)
55
(39 to 77)
912
(955 to 869)
4724
(2653 to 7499)
821
(417 to 1450)
831
(903 to 685)
Whooping cough
Tetanus
2169
(1748 to 3705)
260
(123 to 389)
870
(958 to 801)
Measles
Malaria
181
(134 to 235)
168
(110 to 264)
96
(426 to 528)
5663
(4708 to 6620)
5700
(4375 to 7332)
13
(277 to 409)
14521
(11906 to 16773)
6930
(5536 to 8539)
525
(586 to 450)
1184
(801 to 1573)
494
(345 to 698)
583
(694 to 413)
Neonatal encephalopathy
(birth asphyxia/trauma)
8208
(6513 to 9931)
6115
(4919 to 7240)
253
(381 to 98)
533
(355 to 726)
323
(214 to 487)
406
(582 to 90)
3283
(1863 to 4621)
3422
(2149 to 4793)
46
(173 to 385)
181
(92 to 283)
238
(133 to 380)
303
(159 to 1146)
4899
(3816 to 6549)
2382
(1877 to 2970)
513
(625 to 350)
877
(585 to 1235)
381
(250 to 598)
574
(739 to 278)
4516
(3765 to 5605)
2607
(1979 to 3166)
423
(524 to 301)
Nutritional deciencies
Syphilis
1226
(689 to 1943)
637
(370 to 984)
479
(586 to 355)
1009
(569 to 1576)
569
(325 to 909)
433
(568 to 285)
553
(379 to 791)
224
(164 to 307)
590
(706 to 447)
3177
(2838 to 3550)
1599
(1345 to 1926)
497
(587 to 398)
3664
(3161 to 4439)
2923
(2584 to 3497)
198
(324 to 43)
9064
(7664 to 11382)
5788
(4626 to 7395)
366
(434 to 236)
Congenital anomalies
3036
(2568 to 3754)
2466
(2190 to 2800)
176
(331 to 01)
3436
(2555 to 4935)
2487
(1988 to 3229)
257
(406 to 137)
30
(12 to 61)
24
(11 to 45)
138
(601 to 540)
191
(112 to 343)
127
(84 to 184)
322
(555 to 49)
Other non-communicable
diseases
598
(523 to 705)
433
(324 to 769)
313
(433 to 187)
5437
(4691 to 6428)
3174
(2442 to 4228)
428
(526 to 233)
766
(585 to 951)
464
(375 to 635)
417
(534 to 29)
6895
(5671 to 7763)
3207
(2778 to 3715)
546
(611 to 419)
Road injuries
41
(33 to 51)
38
(26 to 53)
66
(308 to 305)
1052
(887 to 1282)
645
(513 to 795)
383
(526 to 237)
Drowning
27
(19 to 35)
18
(11 to 28)
382
(567 to 169)
2123
(1324 to 2751)
801
(617 to 1114)
633
(741 to 204)
Other injuries
699
(522 to 882)
408
(321 to 580)
441
(559 to 10)
3720
(2809 to 4243)
1762
(1531 to 2037)
537
(608 to 376)
Non-communicable diseases
Injuries
Data in parentheses are 95% uncertainty intervals. Shows major causes of death within each level 1 group that accounted for deaths in children.
140
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Age-standardised
death rates (% change)
Gini coecient
Change
(19902013)
2013
Change
(19902013)
All causes
242%
18204
1940
019
0024
405%
10487
4223
054
0068
230%
3591
137
069
0114
496%
4044
2980
049
0027
245%
928
437
078
0023
Maternal disorders
434%
288
164
069
0085
Neonatal disorders
411%
975
507
044
0068
Nutritional deciencies
289%
800
140
059
0044
372%
296
154
049
0011
Non-communicable diseases
185%
8674
202
013
0021
Neoplasms
148%
1865
644
015
0021
Cardiovascular diseases
219%
5997
751
018
0044
301%
3235
1844
036
0030
Cirrhosis
136%
645
008
030
0028
Digestive diseases
332%
731
331
032
0001
25%
551
024
018
0003
64%
177
004
044
0002
145%
1667
399
030
0026
83%
032
001
018
0012
Neurological disorders
Musculoskeletal disorders
Other non-communicable diseases
176%
249
027
024
0071
Injuries
208%
1731
033
023
0039
85%
580
084
025
0048
Unintentional injuries
255%
921
267
028
0001
207%
606
023
034
0072
659%
085
165
090
0038
Transport injuries
Signicant increase
No signicant increase
Signicant decrease
Articles
Global YLLs
Between 1990 and 2013, large falls occurred for measles,
meningitis, tetanus, syphilis, and whooping cough
(gure 10). Increases of 50% or more are evident for
diabetes, HIV/AIDS, hypertensive heart disease, chronic
kidney disease, Alzheimers disease and other dementias,
interstitial lung disease, and pancreatic cancer. Among
the top ten causes in 1990, nine remain in the top ten in
2013, with HIV/AIDS moving in and tuberculosis
moving to 11th. The largest percentage increases in YLLs
were for HIV/AIDS (34397%, 95% UI 2454844417),
atrial brillation and utter (21189%, 1825524263),
peripheral vascular disease (11979%, 1010413678),
and drug use disorders (11922%, 837714002).
Identication of key transition points in the
comparative importance of dierent causes of premature
142
Articles
30 000
20 000
Other injuries
Drowning
Road injuries
Other non-communicable diseases
SIDS
Congenital anomalies
Other communicable diseases
Nutritional deciencies
Other neonatal disorders and jaundice
Neonatal sepsis
Neonatal encephalopathy
Preterm birth
Syphilis
Malaria
Measles
Diphtheria/tetanus/pertussis
Meningitis and encephalitis
Lower respiratory infections
Intestinal infectious
Diarrhoeal diseases
HIV/AIDS
10 000
B
2000
1500
1000
500
om
eA
W sia
es Pa
te
hrn cic
in
E
co
m A urop
e N us
e
or tral
th as
i
A
Ce m a
nt er
ra ic
So
ut Eas l Eu a
he te ro
rn rn pe
La Eu
tin ro
Am pe
Ce
nt
er
r
a
E
No Tro l L as ica
rth pic atin t A
Af al L Am sia
ric at
a a in eric
nd Am a
M er
An So iddl ica
de ut e E
an he as
La ast t
tin A
A sia
So
ut
Ce mer
he
nt ica
rn
ra
l
su
b- Ca Asia
Sa rib
ha be
ra an
nA
Ea
fr
ste
Oc ica
rn
Ce su
e
nt b- So ani
W ral s Sah uth a
es
te ub- aran Asia
rn Sa
su ha Afr
b- ran ica
Sa
ha Afr
ra ica
nA
fri
ca
in
c
Hi
g
40 000
h-
Hi
g
143
Articles
10 (1 to 1)
20 (2 to 2)
30 (3 to 4)
40 (4 to 4)
51 (5 to 6)
64 (5 to 9)
75 (6 to 9)
80 (6 to 10)
89 (6 to 11)
96 (8 to 11)
115 (11 to 13)
122 (7 to 18)
135 (12 to 18)
145 (12 to 18)
150 (12 to 17)
159 (14 to 18)
171 (12 to 25)
180 (17 to 19)
185 (12 to 21)
196 (18 to 21)
214 (20 to 23)
227 (16 to 33)
235 (21 to 30)
241 (23 to 26)
252 (22 to 29)
268 (25 to 29)
284 (23 to 34)
286 (22 to 33)
287 (27 to 32)
313 (28 to 35)
326 (28 to 36)
332 (29 to 39)
334 (22 to 48)
343 (29 to 39)
356 (25 to 46)
358 (33 to 40)
372 (19 to 61)
372 (35 to 39)
386 (36 to 41)
410 (36 to 45)
413 (38 to 44)
413 (37 to 46)
433 (33 to 53)
449 (42 to 48)
458 (42 to 49)
461 (24 to 71)
484 (40 to 54)
492 (38 to 79)
492 (44 to 59)
493 (44 to 54)
10 (1 to 1)
23 (2 to 3)
27 (2 to 3)
55 (4 to 8)
59 (4 to 8)
60 (4 to 8)
63 (4 to 9)
69 (4 to 10)
87 (6 to 11)
103 (8 to 12)
111 (10 to 12)
113 (10 to 12)
134 (13 to 15)
144 (13 to 16)
150 (14 to 16)
157 (12 to 22)
172 (16 to 19)
179 (16 to 22)
206 (19 to 25)
207 (16 to 24)
211 (19 to 24)
212 (18 to 27)
229 (19 to 26)
245 (20 to 29)
250 (23 to 27)
261 (24 to 29)
279 (26 to 30)
288 (26 to 33)
293 (27 to 31)
319 (30 to 35)
333 (30 to 38)
337 (27 to 37)
337 (30 to 37)
345 (30 to 38)
348 (25 to 46)
350 (17 to 63)
357 (24 to 52)
372 (34 to 40)
387 (37 to 41)
408 (36 to 48)
419 (37 to 48)
438 (40 to 51)
438 (30 to 62)
442 (42 to 48)
452 (36 to 59)
462 (42 to 54)
471 (42 to 54)
474 (39 to 59)
484 (43 to 54)
496 (45 to 55)
Median % change
31% (24 to 41)
48% (54 to 43)
24% (18 to 32)
62% (66 to 57)
15% (2 to 23)
344% (245 to 444)
53% (59 to 45)
5% (26 to 24)
26% (38 to 11)
18% (33 to 4)
31% (40 to 24)
1% (9 to 9)
36% (28 to 45)
9% (3 to 24)
39% (31 to 48)
6% (16 to 38)
67% (59 to 77)
28% (40 to 15)
90% (74 to 103)
46% (54 to 3)
42% (26 to 58)
10% (2 to 21)
43% (53 to 33)
56% (33 to 75)
2% (9 to 5)
23% (32 to 12)
44% (38 to 49)
18% (14 to 40)
89% (81 to 103)
37% (28 to 46)
32% (14 to 47)
22% (35 to 4)
12% (17 to 4)
35% (46 to 15)
46% (57 to 33)
42% (8 to 138)
13% (27 to 1)
31% (18 to 48)
9% (16 to 3)
86% (26 to 194)
37% (44 to 26)
20% (36 to 6)
83% (90 to 68)
74% (67 to 80)
37% (52 to 21)
14% (4 to 23)
27% (10 to 40)
22% (40 to 18)
29% (7 to 49)
43% (23 to 57)
Group 1
Non-communicable
Injuries
Figure 10: Top 50 causes of global years of life lost in 1990 and 2013
An interactive version of this gure is available at http://vizhub.healthdata.org/gbd-compare/. COPD=chronic obstructive pulmonary disease.
Articles
40 000
35 000
30 000
25 000
20 000
15 000
10 000
5000
19
90
19
91
19
92
19
93
19
94
19
95
19
96
19
97
19
98
19
99
20
00
20
01
20
02
20
03
20
04
20
05
20
06
20
07
20
08
20
09
20
10
20
11
20
12
20
13
Other injuries
Interpersonal violence
Self-harm
Drowning
Road injuries
Other non-communicable
diseases
Congenital anomalies
Diabetes
Cirrhosis
COPD
Other cardiovascular
diseases
Cerebrovascular disease
Ischaemic heart disease
Other cancers
Lung cancer
Other communicable,
maternal, neonatal, and
nutritional disorders
Syphilis
Protein-energy
malnutrition
Neonatal disorders
Maternal disorders
Malaria
Measles
Tetanus
Meningitis
Lower respiratory
infections
Diarrhoeal diseases
HIV/AIDS
Tuberculosis
Year
Figure 11: Global years of life lost by large cause groupings for 1990 to 2013
COPD=chronic obstructive pulmonary disease.
Articles
All ages
2013
1990
2013
Rate of change
for deaths
19902013 (%)
Deaths
(thousands)
Population
attributable
fractions (%)
Deaths
(thousands)
Population
attributable
fractions (%)
Deaths
(thousands)
Population
attributable
fractions (%)
Deaths
(thousands)
Population
attributable
fractions (%)
Adenovirus
630
(444 to 899)
39
(27 to 55)
183
(118 to 255)
35
(24 to 49)
813
(559 to 1159)
32
(21 to 44)
318
(215 to 447)
25
(17 to 36)
612%
(678 to 525)
Aeromonas
123
(64 to 214)
08
(04 to 13)
55
(26 to 101)
11
(05 to 19)
280
(167 to 449)
11
(07 to 17)
130
(73 to 220)
10
(06 to 17)
536%
(661 to 378)
Amoebiasis
58
(26 to 100)
04
(02 to 06)
13
(06 to 23)
02
(01 to 05)
183
(89 to 306)
07
(03 to 12)
113
(50 to 197)
09
(04 to 16)
391%
(57 to 175)
Campylobacter enteritis
208
(110 to 319)
13
(07 to 20)
95
(37 to 157)
18
(07 to 30)
284
(164 to 428)
11
(06 to 16)
141
(69 to 224)
11
(05 to 18)
507%
(637 to 375)
Cholera
817
(391 to 1170)
51
(25 to 72)
452
(234 to 676)
87
(45 to 127)
1253
(611 to 1734)
49
(24 to 67)
699
(377 to 970)
55
(30 to 77)
443%
(568 to 266)
Clostridium dicile
21
(20 to 23)
01
(01 to 01)
25
(24 to 27)
05
(04 to 06)
208
(199 to 219)
08
(07 to 09)
415
(391 to 439)
33
(30 to 36)
994%
(843 to 1143)
Cryptosporidiosis
924
(687 to 1251)
58
(43 to 78)
352
(259 to 482)
68
(51 to 93)
988
(728 to 1327)
38
(28 to 52)
419
(300 to 584)
33
(24 to 47)
578%
(648 to 496)
Enteropathogenic
Escherichia coli infection
43
(13 to 78)
03
(01 to 05)
18
(07 to 34)
03
(01 to 07)
43
(13 to 78)
02
(01 to 03)
18
(07 to 34)
01
(01 to 03)
575%
(765 to 32)
Enterotoxigenic
Escherichia coli infection
860
(613 to 1141)
54
(38 to 72)
231
(170 to 304)
44
(34 to 59)
1347
(975 to 1782)
52
(38 to 68)
592
(442 to 777)
47
(35 to 61)
560%
(630 to 469)
Norovirus
73
(27 to 118)
05
(02 to 07)
18
(07 to 31)
03
(01 to 06)
73
(27 to 118)
03
(01 to 05)
18
(07 to 32)
01
(01 to 02)
758%
(851 to 616)
Other Salmonella
infections
192
(111 to 291)
12
(07 to 18)
38
(16 to 67)
07
(03 to 12)
589
(424 to 778)
23
(16 to 30)
243
(160 to 333)
19
(13 to 26)
589%
(654 to 511)
Rotaviral enteritis
3989
(3345 to 4642)
248
(214 to 282)
1224
(966 to 1521)
235
(201 to 272)
4775
(3979 to 5551)
185
(158 to 212)
1766
(1404 to 2184)
140
(114 to 166)
632%
(685 to 571)
Shigellosis
1610
(1300 to 2003)
100
(82 to 122)
334
(249 to 435)
64
(51 to 79)
2542
(2079 to 3117)
99
(82 to 119)
739
(589 to 938)
58
(47 to 73)
709%
(744 to 673)
No identied aetiology*
6524
(5424 to 7831)
406
(353 to 468)
2159
415
(1696 to 2652) (357 to 481)
12409
481
(10968 to 14215) (435 to 535)
7029
(6192 to 796)
556
(514 to 603)
432%
(493 to 361)
Diarrhoea
4271
(398 to 8534)
197
(18 to 391)
1087
(99 to 2269)
120
(11 to 255)
4271
(398 to 8534)
125
(12 to 248)
1087
(99 to 2269)
41
(04 to 88)
751%
(791 to 712)
Inuenza
363
(142 to 735)
17
(07 to 33)
151
(57 to 304)
17
(06 to 33)
851
(361 to 1562)
25
(11 to 45)
1054
(453 to 1881)
40
(17 to 73)
240%
(34 to 477)
Pneumococcal
pneumonia
6524
(4026 to 8794)
301
(190 to 402)
2640
(1557 to 3658)
292
(180 to 392)
9195
(5531 to 13205)
269
(163 to 384)
5944
(2956 to 9702)
224
(114 to 359)
361%
(527 to 198)
Respiratory syncytial
virus pneumonia
1451
(827 to 2280)
67
(38 to 105)
411
(230 to 655)
45
(26 to 71)
1855
(1144 to 2686)
54
(35 to 79)
815
(536 to 1099)
31
(20 to 42)
557%
(63 to 472)
No identied aetiology*
9072
419
(4073 to 14513) (190 to 667)
4762
(3133 to 6516)
526
(352 to 702)
18034
(12118 to 24525)
527
(354 to 711)
17626
(13853 to 21341)
665
(528 to 799)
08%
(198 to 229)
Data in parentheses are 95% uncertainty intervals. *Number or proportion of diarrhea or lower respiratory infection deaths attributable to any diarrhea or lower respiratory infection pathogens. Because of
interaction between pathogens (especially for lower respiratory infection), the value is the minimum amount of unexplained deaths.
Table 4: Counterfactual deaths and population attributable fractions for diarrhoea and lower respiratory infection pathogens for 1990 and 2013
Articles
Articles
10
Global
IHD
LRI
Stroke
Diarrhoea
Road injuries
HIV/AIDS
NN preterm
Malaria
NN encephalitis
Congenital
Developed
IHD
Stroke
Lung C
Self harm
Alzheimer's
Cirrhosis
COPD
Colorectal C
LRI
Road injuries
Developing
LRI
IHD
Stroke
Diarrhoea
HIV/AIDS
NN preterm
Malaria
Road injuries
NN encephalitis
Congenital
High-income
IHD
Lung C
Stroke
Alzheimer's
COPD
Self harm
Colorectal C
LRI
Road injuries
Cirrhosis
Australasia
IHD
Lung C
Stroke
Self harm
Colorectal C
Alzheimer's
COPD
Road injuries
Breast C
Diabetes
Australia
IHD
Lung C
Stroke
Self harm
Alzheimer's
Colorectal C
COPD
Road injuries
Breast C
Diabetes
New Zealand
IHD
Lung C
Stroke
Colorectal C
COPD
Self harm
Alzheimer's
Road injuries
Breast C
Congenital
Stroke
IHD
Self harm
Lung C
LRI
Stomach C
Liver C
Colorectal C
Cirrhosis
COPD
Brunei
IHD
Stroke
Diabetes
Road injuries
Congenital
Lung C
LRI
HIV/AIDS
COPD
Colorectal C
Japan
Stroke
IHD
LRI
Lung C
Self harm
Stomach C
Liver C
Colorectal C
COPD
Pancreatic C
Singapore
IHD
LRI
Stroke
Lung C
Colorectal C
Self harm
CKD
Breast C
COPD
Liver C
South Korea
Stroke
Self harm
Lung C
Liver C
IHD
Stomach C
Cirrhosis
Road injuries
Diabetes
Colorectal C
IHD
Lung C
Alzheimer's
COPD
Stroke
Road injuries
Self harm
Cirrhosis
Diabetes
Colorectal C
Canada
IHD
Lung C
Alzheimer's
Stroke
Self harm
Colorectal C
COPD
Road injuries
Breast C
Diabetes
USA
IHD
Lung C
COPD
Alzheimer's
Stroke
Road injuries
Self harm
Cirrhosis
Diabetes
Colorectal C
IHD
Stroke
LRI
COPD
Road injuries
Lung C
Congenital
Cirrhosis
Self harm
Colorectal C
Argentina
IHD
Stroke
LRI
COPD
Road injuries
Congenital
Lung C
NN preterm
Colorectal C
Self harm
Chile
IHD
Stroke
Cirrhosis
Road injuries
Self harm
Stomach C
LRI
Alzheimer's
Congenital
Lung C
Uruguay
IHD
Stroke
Lung C
Alzheimer's
COPD
LRI
Road injuries
Self harm
Colorectal C
Congenital
Western Europe
IHD
Lung C
Stroke
Alzheimer's
Colorectal C
COPD
Self harm
Cirrhosis
Breast C
LRI
Andorra
IHD
Lung C
Stroke
Alzheimer's
Colorectal C
COPD
LRI
Self harm
HIV/AIDS
Pancreatic C
Austria
IHD
Lung C
Stroke
Alzheimer's
Self harm
Cirrhosis
Colorectal C
COPD
Breast C
Diabetes
Belgium
IHD
Lung C
Stroke
Self harm
COPD
Alzheimer's
LRI
Colorectal C
Breast C
Road injuries
Cyprus
IHD
Stroke
Lung C
Road injuries
Diabetes
Alzheimer's
Breast C
Colorectal C
COPD
LRI
Denmark
IHD
Lung C
Stroke
COPD
Colorectal C
Alzheimer's
Cirrhosis
Self harm
LRI
Diabetes
Finland
IHD
Stroke
Alzheimer's
Lung C
Self harm
Cirrhosis
Colorectal C
Pancreatic C
Falls
Alcohol
France
IHD
Lung C
Stroke
Self harm
Colorectal C
Alzheimer's
Cirrhosis
Breast C
Road injuries
Other cardio
Germany
IHD
Lung C
Stroke
Alzheimer's
Colorectal C
COPD
Cirrhosis
Self harm
Breast C
Pancreatic C
Greece
IHD
Stroke
Lung C
Alzheimer's
COPD
Road injuries
Colorectal C
Breast C
LRI
CKD
Iceland
IHD
Lung C
Stroke
Alzheimer's
Self harm
Colorectal C
COPD
Breast C
Prostate C
Road injuries
Ireland
IHD
Lung C
Stroke
Self harm
COPD
Colorectal C
LRI
Alzheimer's
Breast C
Congenital
Israel
IHD
Lung C
Alzheimer's
Diabetes
Stroke
Colorectal C
Road injuries
CKD
Congenital
Breast C
Italy
IHD
Stroke
Lung C
Alzheimer's
Colorectal C
COPD
Diabetes
Breast C
Cirrhosis
Road injuries
Luxembourg
IHD
Lung C
Stroke
Self harm
COPD
Colorectal C
Cirrhosis
Alzheimer's
Breast C
Road injuries
Malta
IHD
Stroke
Lung C
Colorectal C
Breast C
COPD
Congenital
LRI
Pancreatic C
Diabetes
Netherlands
IHD
Lung C
Stroke
Colorectal C
COPD
Alzheimer's
Breast C
LRI
Self harm
Pancreatic C
Norway
IHD
Lung C
Stroke
Alzheimer's
Colorectal C
COPD
Self harm
LRI
Drugs
Breast C
Portugal
Stroke
IHD
Lung C
LRI
Colorectal C
Alzheimer's
Cirrhosis
COPD
Stomach C
Road injuries
Spain
IHD
Lung C
Stroke
Alzheimer's
Colorectal C
COPD
Cirrhosis
LRI
Breast C
Road injuries
Sweden
IHD
Stroke
Lung C
Colorectal C
Self harm
Alzheimer's
COPD
Prostate C
LRI
Breast C
Switzerland
IHD
Lung C
Stroke
Alzheimer's
Self harm
Colorectal C
Breast C
Other cardio
COPD
Pancreatic C
UK
IHD
Lung C
Stroke
COPD
Alzheimer's
LRI
Colorectal C
Breast C
Cirrhosis
Self harm
England
IHD
Lung C
Stroke
COPD
Alzheimer's
LRI
Colorectal C
Breast C
Cirrhosis
Self harm
Northern Ireland
IHD
Lung C
Stroke
COPD
LRI
Colorectal C
Alzheimer's
Self harm
Breast C
Cirrhosis
Scotland
IHD
Lung C
Stroke
COPD
Alzheimer's
Colorectal C
LRI
Cirrhosis
Self harm
Breast C
Wales
IHD
Lung C
Stroke
Alzheimer's
COPD
LRI
Colorectal C
Breast C
Cirrhosis
Self harm
IHD
Stroke
LRI
Self harm
Cirrhosis
Lung C
CMP
Road injuries
COPD
Colorectal C
Central Asia
IHD
LRI
Stroke
NN encephalitis
Cirrhosis
Congenital
Road injuries
Self harm
NN preterm
Drowning
Armenia
IHD
Stroke
Lung C
Diabetes
Road injuries
Cirrhosis
Congenital
LRI
COPD
Breast C
Azerbaijan
IHD
LRI
Stroke
NN encephalitis
Congenital
Cirrhosis
Road injuries
NN preterm
Diabetes
TB
Georgia
IHD
Stroke
COPD
Cirrhosis
Lung C
Road injuries
LRI
NN encephalitis
Other cardio
Alzheimer's
Kazakhstan
IHD
Stroke
Self harm
Road injuries
Cirrhosis
LRI
Congenital
NN encephalitis
Violence
COPD
Kyrgyzstan
IHD
Stroke
LRI
Cirrhosis
NN encephalitis
NN preterm
Congenital
Road injuries
COPD
Self harm
Mongolia
IHD
Stroke
LRI
Liver C
NN encephalitis
Cirrhosis
Self harm
Congenital
Road injuries
NN preterm
Tajikistan
LRI
IHD
NN encephalitis
NN preterm
Diarrhoea
Congenital
Stroke
Drowning
Cirrhosis
Meningitis
Turkmenistan
IHD
LRI
Stroke
NN encephalitis
Diarrhoea
Cirrhosis
Congenital
NN preterm
Road injuries
Drowning
Uzbekistan
IHD
LRI
Stroke
NN encephalitis
Cirrhosis
Road injuries
Congenital
HTN HD
Drowning
Self harm
Central Europe
IHD
Stroke
Lung C
Cirrhosis
COPD
Self harm
Colorectal C
Alzheimer's
HTN HD
Road injuries
Albania
IHD
Stroke
LRI
Lung C
Other cardio
Road injuries
COPD
Violence
Stomach C
Congenital
IHD
Stroke
Lung C
CMP
Diabetes
COPD
Colorectal C
Alzheimer's
Self harm
Cirrhosis
Bulgaria
IHD
Stroke
COPD
HTN HD
Lung C
Other cardio
Colorectal C
Alzheimer's
Cirrhosis
LRI
Croatia
IHD
Stroke
Lung C
Colorectal C
Cirrhosis
COPD
Alzheimer's
Self harm
Road injuries
HTN HD
Czech Republic
IHD
Stroke
Lung C
Colorectal C
Cirrhosis
Self harm
Alzheimer's
COPD
LRI
Other cardio
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Croatia
IHD
Stroke
Lung C
Colorectal C
Cirrhosis
COPD
Alzheimer s
Self harm
Road injuries
HTN HD
Czech Republic
IHD
Stroke
Lung C
Colorectal C
Cirrhosis
Self harm
Alzheimer's
COPD
LRI
Other cardio
Hungary
IHD
Stroke
Lung C
Cirrhosis
Colorectal C
Self harm
COPD
Alzheimer's
HTN HD
Breast C
Macedonia
Stroke
IHD
Lung C
Diabetes
HTN HD
Colorectal C
COPD
Stomach C
Alzheimer's
Road injuries
Montenegro
IHD
Stroke
Lung C
Self harm
Road injuries
CMP
Breast C
Diabetes
Alzheimer's
Colorectal C
Poland
IHD
Stroke
Lung C
Self harm
COPD
Cirrhosis
Road injuries
Colorectal C
Alzheimer's
LRI
Romania
IHD
Stroke
Cirrhosis
Lung C
LRI
HTN HD
Alzheimer's
CMP
COPD
Colorectal C
Serbia
IHD
Stroke
CMP
Lung C
Self harm
Colorectal C
COPD
Alzheimer's
Diabetes
Breast C
Slovakia
IHD
Stroke
Lung C
Cirrhosis
Colorectal C
LRI
Self harm
Alzheimer's
Road injuries
Other cardio
Slovenia
IHD
Stroke
Lung C
Self harm
Cirrhosis
Colorectal C
Alzheimer's
COPD
CMP
Road injuries
Eastern Europe
IHD
Stroke
Self harm
CMP
Cirrhosis
Lung C
Road injuries
LRI
Violence
Alcohol
Belarus
IHD
Stroke
Self harm
Lung C
Road injuries
Cirrhosis
Stomach C
COPD
CMP
Alcohol
Estonia
IHD
Stroke
Lung C
Self harm
HTN HD
Alzheimer's
Cirrhosis
Alcohol
Colorectal C
CMP
Latvia
IHD
Stroke
CMP
Lung C
Self harm
Alzheimer's
Colorectal C
Cirrhosis
Stomach C
Road injuries
Lithuania
IHD
Stroke
Self harm
Lung C
Cirrhosis
Alzheimer's
Road injuries
Colorectal C
CMP
Stomach C
Moldova
IHD
Stroke
Cirrhosis
LRI
Self harm
Lung C
Road injuries
COPD
Colorectal C
Congenital
Russia
IHD
Stroke
CMP
Self harm
Cirrhosis
Lung C
Road injuries
LRI
Violence
Alcohol
Ukraine
IHD
Stroke
Cirrhosis
Self harm
HIV/AIDS
Lung C
Road injuries
Colorectal C
Alzheimer's
CMP
IHD
Violence
Road injuries
Stroke
LRI
Congenital
Diabetes
Cirrhosis
NN preterm
CKD
LRI
Road injuries
IHD
Congenital
NN preterm
Stroke
F Body Asp
Cirrhosis
NN encephalitis
CKD
Bolivia
LRI
F Body Asp
Road injuries
NN preterm
IHD
Congenital
NN encephalitis
Stroke
Cirrhosis
NN sepsis
Ecuador
LRI
Road injuries
IHD
Congenital
Violence
Stroke
CKD
NN preterm
Self harm
Cirrhosis
Peru
LRI
IHD
Road injuries
Congenital
Stroke
NN preterm
Cirrhosis
F Body Asp
NN encephalitis
NN sepsis
Caribbean
IHD
Stroke
LRI
HIV/AIDS
Road injuries
Diarrhoea
Diabetes
NN preterm
Congenital
NN sepsis
IHD
Stroke
Diabetes
LRI
Road injuries
HIV/AIDS
NN preterm
Violence
CKD
Congenital
Barbados
IHD
Diabetes
Stroke
LRI
CKD
Road injuries
Violence
HTN HD
Breast C
HIV/AIDS
Belize
IHD
Diabetes
Violence
Stroke
Road injuries
NN preterm
Congenital
LRI
HIV/AIDS
Self harm
Cuba
IHD
Stroke
Lung C
LRI
Self harm
COPD
Road injuries
Colorectal C
Alzheimer's
CKD
Dominica
IHD
Stroke
Diabetes
LRI
Road injuries
Violence
NN preterm
CKD
Congenital
HTN HD
Dominican Republic
IHD
Road injuries
Stroke
NN preterm
Congenital
LRI
Violence
NN sepsis
Diabetes
CKD
Grenada
IHD
Stroke
Diabetes
LRI
Road injuries
HIV/AIDS
Violence
CKD
Self harm
Congenital
Guyana
IHD
Stroke
HIV/AIDS
Diabetes
Road injuries
LRI
Congenital
Self harm
Violence
NN preterm
Haiti
HIV/AIDS
LRI
Diarrhoea
Stroke
PEM
NN sepsis
IHD
NN preterm
Congenital
NN encephalitis
Jamaica
Stroke
Diabetes
Violence
IHD
NN preterm
CKD
LRI
Congenital
HIV/AIDS
Alzheimer's
Saint Lucia
IHD
Stroke
Diabetes
LRI
Violence
Road injuries
HIV/AIDS
NN preterm
CKD
Congenital
VCT
IHD
Stroke
Diabetes
NN preterm
Violence
HIV/AIDS
LRI
Road injuries
Congenital
CKD
Suriname
IHD
Stroke
NN preterm
Congenital
Diabetes
LRI
Road injuries
HIV/AIDS
Self harm
CKD
The Bahamas
IHD
Stroke
Diabetes
HIV/AIDS
Violence
Road injuries
CKD
LRI
HTN HD
NN preterm
TTO
IHD
Diabetes
Stroke
Violence
Road injuries
HIV/AIDS
LRI
CKD
Congenital
Self harm
Violence
IHD
Road injuries
CKD
Congenital
LRI
Diabetes
Cirrhosis
Stroke
NN preterm
Colombia
Violence
IHD
Road injuries
Stroke
Congenital
LRI
COPD
NN preterm
Diabetes
Self harm
Costa Rica
IHD
Road injuries
Congenital
CKD
Stroke
Cirrhosis
Violence
Self harm
Stomach C
COPD
El Salvador
Violence
IHD
Road injuries
CKD
LRI
Congenital
Alcohol
Cirrhosis
Diabetes
Stroke
Guatemala
LRI
Violence
Diarrhoea
NN preterm
IHD
PEM
Congenital
Cirrhosis
Diabetes
Road injuries
Honduras
IHD
Violence
Congenital
NN preterm
Stroke
COPD
Diarrhoea
LRI
Road injuries
Cirrhosis
Mexico
IHD
CKD
Diabetes
Cirrhosis
Violence
Road injuries
Congenital
LRI
Stroke
NN preterm
Nicaragua
Congenital
LRI
CKD
IHD
NN preterm
Road injuries
Stroke
Cirrhosis
Violence
Diabetes
Panama
IHD
Violence
Congenital
Road injuries
Stroke
LRI
CKD
Diabetes
NN preterm
HIV/AIDS
Venezuela
Violence
IHD
Road injuries
Stroke
Congenital
Diabetes
CKD
LRI
Self harm
NN preterm
IHD
Violence
Stroke
Road injuries
LRI
Congenital
Diabetes
NN preterm
Cirrhosis
COPD
Brazil
IHD
Violence
Stroke
Road injuries
LRI
Congenital
Diabetes
Cirrhosis
NN preterm
COPD
Paraguay
IHD
Road injuries
Stroke
Congenital
NN preterm
LRI
Violence
Diabetes
CKD
NN encephalitis
Stroke
IHD
Road injuries
COPD
Lung C
LRI
Liver C
Congenital
Cirrhosis
Stomach C
East Asia
Stroke
IHD
Road injuries
COPD
Lung C
Liver C
Stomach C
Congenital
LRI
Cirrhosis
China
Stroke
IHD
Road injuries
COPD
Lung C
Liver C
Stomach C
Congenital
LRI
Cirrhosis
North Korea
Stroke
IHD
Lung C
COPD
Road injuries
Liver C
Stomach C
Self harm
LRI
Congenital
IHD
Stroke
Liver C
Lung C
Diabetes
Cirrhosis
Self harm
Road injuries
LRI
Colorectal C
Oceania
LRI
IHD
Diabetes
Diarrhoea
Congenital
Malaria
NN preterm
Stroke
Road injuries
Asthma
FSM
IHD
Diabetes
Stroke
LRI
Road injuries
Congenital
Asthma
Self harm
CKD
COPD
Fiji
IHD
Diabetes
Stroke
LRI
Congenital
NN preterm
CKD
Road injuries
Breast C
COPD
Kiribati
Stroke
Diabetes
IHD
LRI
Congenital
Road injuries
Diarrhoea
Asthma
Self harm
NN preterm
Marshall Islands
IHD
Diabetes
LRI
Stroke
Congenital
NN preterm
Road injuries
CKD
Diarrhoea
Self harm
PNG
LRI
IHD
Diarrhoea
Diabetes
Malaria
NN preterm
Congenital
Road injuries
HIV/AIDS
Asthma
Samoa
Diabetes
IHD
Stroke
LRI
Congenital
Road injuries
CKD
Violence
Asthma
Self harm
Solomon Islands
IHD
Diabetes
Stroke
LRI
Diarrhoea
Congenital
NN preterm
Asthma
TB
Road injuries
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Samoa
Diabetes
IHD
Stroke
LRI
Congenital
Road injuries
CKD
Violence
Asthma
Self harm
Solomon Islands
IHD
Diabetes
Stroke
LRI
Diarrhoea
Congenital
NN preterm
Asthma
TB
Road injuries
Tonga
IHD
Diabetes
LRI
Stroke
NN preterm
Congenital
Road injuries
Lung C
Breast C
Meningitis
Vanuatu
IHD
LRI
Diabetes
Stroke
NN preterm
Congenital
Road injuries
Diarrhoea
Asthma
TB
Southeast Asia
Stroke
IHD
LRI
Road injuries
TB
NN preterm
Diabetes
Congenital
Cirrhosis
NN encephalitis
Cambodia
IHD
LRI
NN preterm
Stroke
Congenital
Road injuries
NN encephalitis
TB
Diarrhoea
Self harm
Indonesia
Stroke
IHD
LRI
TB
Road injuries
NN encephalitis
Diabetes
Diarrhoea
NN preterm
Cirrhosis
Laos
LRI
NN preterm
IHD
Stroke
Diarrhoea
Road injuries
Congenital
NN encephalitis
TB
Drowning
Malaysia
IHD
Road injuries
Stroke
LRI
Lung C
Congenital
COPD
Diabetes
HIV/AIDS
CKD
Maldives
IHD
Stroke
Congenital
NN encephalitis
NN preterm
Drowning
COPD
Road injuries
CKD
LRI
Myanmar
Stroke
LRI
Cirrhosis
TB
IHD
Malaria
NN preterm
Road injuries
Lung C
NN encephalitis
Philippines
IHD
LRI
Stroke
TB
NN preterm
Congenital
Diabetes
Violence
Road injuries
NN encephalitis
Sri Lanka
IHD
Self harm
Stroke
Diabetes
COPD
Road injuries
Cirrhosis
LRI
Congenital
Violence
Thailand
IHD
Road injuries
Stroke
LRI
Liver C
Cirrhosis
CKD
HIV/AIDS
Self harm
Diabetes
Timor-Leste
LRI
NN preterm
Congenital
Diarrhoea
IHD
Stroke
NN encephalitis
Road injuries
Drowning
Maternal
Vietnam
Stroke
Road injuries
LRI
Liver C
NN preterm
IHD
Drowning
Cirrhosis
Congenital
Lung C
South Asia
IHD
LRI
NN encephalitis
NN preterm
Diarrhoea
TB
Stroke
COPD
Road injuries
Self harm
Afghanistan
LRI
NN preterm
IHD
Diarrhoea
Congenital
Road injuries
Stroke
Meningitis
Maternal
TB
Bangladesh
Stroke
IHD
NN encephalitis
LRI
NN preterm
Drowning
NN sepsis
Cirrhosis
Self harm
Congenital
Bhutan
IHD
LRI
NN encephalitis
Stroke
NN preterm
Road injuries
Congenital
Cirrhosis
COPD
NN sepsis
India
IHD
LRI
TB
NN encephalitis
NN preterm
Diarrhoea
Stroke
COPD
Self harm
Road injuries
Nepal
LRI
IHD
NN encephalitis
Stroke
Diarrhoea
Self harm
TB
NN preterm
NN sepsis
COPD
Pakistan
LRI
NN encephalitis
Diarrhoea
IHD
NN preterm
NN sepsis
Stroke
Meningitis
Congenital
TB
IHD
NN preterm
Congenital
Stroke
Road injuries
LRI
Cirrhosis
COPD
Diabetes
Diarrhoea
Algeria
NN preterm
IHD
Stroke
Congenital
Road injuries
Diabetes
LRI
NN encephalitis
CKD
NN sepsis
Bahrain
IHD
Road injuries
Diabetes
Self harm
Congenital
Stroke
NN preterm
Drugs
CKD
Breast C
Egypt
IHD
Stroke
Cirrhosis
Congenital
LRI
COPD
Other cardio
NN preterm
CKD
Road injuries
Iran
IHD
NN preterm
Congenital
Road injuries
Stroke
LRI
Other cardio
HTN HD
COPD
Self harm
Iraq
NN preterm
IHD
Congenital
Stroke
LRI
CKD
Road injuries
Violence
Diabetes
Diarrhoea
Jordan
Congenital
IHD
NN preterm
LRI
Stroke
Road injuries
Drowning
Diabetes
CKD
NN encephalitis
Kuwait
IHD
Congenital
Road injuries
NN preterm
Stroke
LRI
CKD
HTN HD
Diabetes
Cirrhosis
Lebanon
IHD
Congenital
Stroke
Lung C
Road injuries
Diabetes
Breast C
NN preterm
COPD
CKD
Libya
IHD
Stroke
Congenital
Road injuries
NN preterm
Diabetes
LRI
CKD
COPD
Lung C
Morocco
NN preterm
IHD
Diabetes
Stroke
LRI
Road injuries
Congenital
NN encephalitis
Drugs
NN sepsis
Oman
Road injuries
IHD
Stroke
Diabetes
Congenital
LRI
Other cardio
NN preterm
Drowning
CKD
Palestine
Congenital
IHD
Stroke
LRI
NN preterm
Road injuries
CKD
Diabetes
Violence
Drugs
Qatar
Road injuries
Congenital
IHD
NN preterm
Self harm
Stroke
Diabetes
Falls
Oth mech
Drowning
Saudi Arabia
Road injuries
IHD
Congenital
NN preterm
Stroke
CKD
LRI
Falls
NN sepsis
Drugs
Sudan
NN preterm
IHD
Congenital
Diarrhoea
LRI
Stroke
Road injuries
Malaria
HIV/AIDS
Vis Leish
Syria
War
IHD
Stroke
Congenital
Road injuries
COPD
NN preterm
LRI
Endocrine
Typhoid
Tunisia
IHD
Road injuries
Stroke
Congenital
NN preterm
Lung C
LRI
COPD
Diabetes
CKD
Turkey
IHD
Stroke
Lung C
Congenital
COPD
Road injuries
NN preterm
Diabetes
LRI
Stomach C
UAE
Road injuries
IHD
Congenital
Stroke
Self harm
LRI
Drugs
NN preterm
Falls
Diabetes
Yemen
NN preterm
IHD
Diarrhoea
Congenital
LRI
Stroke
Malaria
Road injuries
Maternal
COPD
Sub-Saharan Africa
HIV/AIDS
Malaria
LRI
Diarrhoea
NN preterm
NN encephalitis
PEM
Congenital
NN sepsis
TB
LRI
Diarrhoea
Malaria
PEM
HIV/AIDS
NN preterm
Congenital
TB
NN encephalitis
Meningitis
Angola
LRI
Diarrhoea
HIV/AIDS
Malaria
Congenital
PEM
NN preterm
NN encephalitis
TB
Road injuries
CAR
HIV/AIDS
LRI
Diarrhoea
Malaria
TB
NN preterm
PEM
NN encephalitis
Syphilis
Meningitis
Republic of Congo
HIV/AIDS
LRI
Malaria
Congenital
Stroke
NN preterm
Diarrhoea
Measles
NN encephalitis
TB
DR Congo
Diarrhoea
LRI
PEM
Malaria
NN preterm
HIV/AIDS
Congenital
TB
NN encephalitis
Meningitis
Equator Guinea
HIV/AIDS
LRI
Malaria
Congenital
Road injuries
Diarrhoea
Stroke
PEM
NN preterm
NN encephalitis
Gabon
HIV/AIDS
LRI
Malaria
Stroke
Road injuries
Congenital
NN encephalitis
TB
IHD
NN preterm
HIV/AIDS
LRI
Malaria
Diarrhoea
TB
NN preterm
NN encephalitis
PEM
NN sepsis
Congenital
Burundi
Malaria
LRI
Diarrhoea
TB
HIV/AIDS
NN preterm
PEM
NN encephalitis
NN sepsis
Congenital
Comoros
LRI
TB
Diarrhoea
NN preterm
Malaria
NN encephalitis
NN sepsis
Stroke
Road injuries
Congenital
Djibouti
HIV/AIDS
LRI
Malaria
Diarrhoea
TB
Stroke
NN encephalitis
PEM
NN preterm
Congenital
Eritrea
Diarrhoea
LRI
TB
HIV/AIDS
Malaria
NN preterm
PEM
Maternal
NN encephalitis
NN sepsis
Ethiopia
LRI
Diarrhoea
HIV/AIDS
TB
NN preterm
NN encephalitis
Malaria
NN sepsis
Congenital
Stroke
Kenya
HIV/AIDS
LRI
Diarrhoea
TB
NN preterm
NN encephalitis
Malaria
Congenital
NN sepsis
PEM
Madagascar
LRI
Diarrhoea
Stroke
NN preterm
PEM
Syphilis
Malaria
NN sepsis
Congenital
Meningitis
Malawi
HIV/AIDS
LRI
Diarrhoea
PEM
TB
NN preterm
Malaria
Congenital
NN encephalitis
Meningitis
Mauritius
Diabetes
IHD
Stroke
CKD
Cirrhosis
LRI
Road injuries
Self harm
HTN HD
Congenital
Mozambique
HIV/AIDS
Malaria
LRI
Diarrhoea
TB
NN sepsis
NN encephalitis
Syphilis
NN preterm
Road injuries
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Articles
Mozambique
HIV/AIDS
Malaria
LRI
Diarrhoea
TB
NN sepsis
NN encephalitis
Syphilis
NN preterm
Road injuries
Rwanda
LRI
HIV/AIDS
Malaria
Diarrhoea
NN preterm
NN encephalitis
NN sepsis
TB
Road injuries
PEM
Seychelles
IHD
Stroke
LRI
HTN HD
Cirrhosis
Drowning
Road injuries
Self harm
Congenital
CKD
Somalia
Diarrhoea
LRI
Malaria
TB
PEM
NN preterm
Meningitis
NN encephalitis
Tetanus
NN sepsis
South Sudan
LRI
Diarrhoea
HIV/AIDS
TB
PEM
Syphilis
Meningitis
Maternal
Malaria
NN preterm
Tanzania
HIV/AIDS
LRI
Malaria
Diarrhoea
TB
Congenital
PEM
NN encephalitis
Syphilis
NN sepsis
Uganda
HIV/AIDS
Malaria
LRI
Diarrhoea
NN preterm
NN encephalitis
NN sepsis
TB
PEM
Road injuries
Zambia
HIV/AIDS
Malaria
LRI
Diarrhoea
PEM
TB
NN encephalitis
NN sepsis
Congenital
Meningitis
HIV/AIDS
LRI
Diarrhoea
TB
Violence
Stroke
NN preterm
Road injuries
IHD
NN encephalitis
Botswana
HIV/AIDS
TB
LRI
Diarrhoea
Road injuries
Self harm
NN preterm
NN encephalitis
Maternal
Violence
Lesotho
HIV/AIDS
TB
Diarrhoea
LRI
NN preterm
Violence
NN encephalitis
Self harm
Stroke
Road injuries
Namibia
HIV/AIDS
TB
LRI
Diarrhoea
Stroke
Self harm
Road injuries
NN preterm
IHD
Violence
South Africa
HIV/AIDS
LRI
TB
Diarrhoea
Violence
Stroke
Road injuries
IHD
Diabetes
NN preterm
Swaziland
HIV/AIDS
LRI
Diarrhoea
TB
Road injuries
NN preterm
Self harm
Violence
Stroke
NN encephalitis
Zimbabwe
HIV/AIDS
LRI
Diarrhoea
TB
NN preterm
NN encephalitis
Stroke
PEM
Malaria
Meningitis
Malaria
LRI
HIV/AIDS
Diarrhoea
NN preterm
NN encephalitis
Sickle
Road injuries
PEM
NN sepsis
Benin
Malaria
LRI
HIV/AIDS
Diarrhoea
NN preterm
NN encephalitis
Congenital
NN sepsis
Road injuries
PEM
Burkina Faso
Malaria
LRI
Diarrhoea
NN preterm
Congenital
Meningitis
NN encephalitis
NN sepsis
Road injuries
HIV/AIDS
Cameroon
HIV/AIDS
LRI
Malaria
Diarrhoea
Road injuries
NN preterm
NN encephalitis
Congenital
PEM
NN sepsis
Cape Verde
Stroke
IHD
Congenital
LRI
Stomach C
NN encephalitis
Liver C
Violence
COPD
NN preterm
Chad
Diarrhoea
LRI
Malaria
HIV/AIDS
PEM
NN preterm
NN encephalitis
Meningitis
Tetanus
Congenital
Cte dIvoire
LRI
HIV/AIDS
Malaria
Diarrhoea
NN preterm
NN encephalitis
NN sepsis
Road injuries
Congenital
PEM
Ghana
Malaria
LRI
HIV/AIDS
NN sepsis
NN preterm
PEM
NN encephalitis
Stroke
Road injuries
Congenital
Guinea
Malaria
LRI
Diarrhoea
HIV/AIDS
NN preterm
NN encephalitis
PEM
NN sepsis
Meningitis
Congenital
Guinea-Bissau
Malaria
HIV/AIDS
LRI
Diarrhoea
NN preterm
PEM
NN encephalitis
Meningitis
Road injuries
NN sepsis
Liberia
Malaria
LRI
Diarrhoea
HIV/AIDS
NN preterm
NN encephalitis
NN sepsis
PEM
Congenital
Stroke
Mali
Malaria
Diarrhoea
LRI
PEM
NN preterm
NN encephalitis
NN sepsis
Meningitis
Congenital
HIV/AIDS
Mauritania
LRI
Malaria
Diarrhoea
NN encephalitis
NN preterm
Road injuries
NN sepsis
Congenital
Stroke
Maternal
Niger
Malaria
Diarrhoea
LRI
PEM
NN preterm
Meningitis
NN encephalitis
Congenital
NN sepsis
TB
Nigeria
Malaria
LRI
HIV/AIDS
Sickle
Road injuries
NN preterm
NN encephalitis
Diarrhoea
PEM
NN sepsis
LRI
Malaria
Stroke
NN preterm
NN encephalitis
NN sepsis
Congenital
PEM
Diarrhoea
IHD
Senegal
Malaria
LRI
Diarrhoea
NN preterm
NN encephalitis
NN sepsis
HIV/AIDS
Congenital
Road injuries
PEM
Sierra Leone
Malaria
LRI
HIV/AIDS
PEM
NN preterm
Diarrhoea
NN encephalitis
Congenital
NN sepsis
Meningitis
The Gambia
Malaria
LRI
Diarrhoea
Congenital
NN preterm
HIV/AIDS
NN sepsis
NN encephalitis
Road injuries
PEM
Togo
Malaria
LRI
HIV/AIDS
Diarrhoea
NN preterm
NN encephalitis
Congenital
PEM
NN sepsis
Road injuries
Figure 12: Top ten causes in 2013 of years of life lost by location
The top 15 global causes of years of life lost are coloured. VCT=Saint Vincent and the Grenadines. TTO=Trinidad and Tobago. FSM=Federated States of Micronesia. PNG=Papua New Guinea. UAE=United
Arab Emirates. CAR=Central African Republic. STP=So Tom and Princpe. IHD=ischaemic heart disease. LRI=lower respiratory infections. Road inj=road injuries. NN Preterm=preterm birth
complications. NN enceph=neonatal encephalitis. Congenital=congenital disorders. C=cancer. COPD=chronic obstructive pulmonary disease. CKD=chronic kidney disease. CMP=cardiomyopathies.
Other cardio=other cardiovascular disease. Drugs=drug use disorders. Alcohol=alcohol use disorders. Violence=interpersonal violence. HTN HD=hypertensive heart disease. F body asp=pulmonary
aspiration and foreign body in airway. NN sepsis=neonatal sepsis. PEM=proteinenergy malnutrition. TB=tuberculosis. Vis leish=visceral leishmaniasis. Other mech=other mechanical forces.
Endocrine=endocrine, metabolic, blood, and immune disorders. Maternal=maternal disorders. Sickle=sickle cell disorders.
Articles
Discussion
Main ndings
The GBD 2013 incorporates many new datasets for cause
of death, particularly from China, and new data for
155 other countries. Compared with the GBD 2010, it
provides the most comprehensive and up-to-date
assessment of causes of death. The results for the GBD
2013 are based on re-estimation of all causes from 1990 to
2013, and thus supersede all previously published GBD
time series (panel). Publication of country-level results
provides many opportunities for comparing a countrys
performance with that of its peers.
On the broadest level, our analysis of 240 causes of
death for 188 countries conrms that global life
expectancy at birth has continued to improve over the
past 23 years and these improvements are driven largely
by falls in diarrhoea, lower respiratory infections, and
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Convergence or divergence?
Ambitious goals have been set for maternal and child
mortality,8486 such as the end of preventable maternal and
child death in a generation. The Lancet Commission
Global health 2035: a world converging within a generation
has argued that a grand convergence in health is possible
between high-income, middle-income, and low-income
countries.24 Trends in the past 23 years provide an
important starting point for framing how great a challenge
achieving these aspirations will be and the political will
and nancial resources required. Part of the answer
depends on how the goals are framedfor example, what
does convergence mean? In the development literature on
economic convergence,8789 convergence has been framed
in terms of poverty rates or in terms of income inequality
measured by the Gini coecient or other measures of
inequality. Work on convergence in life expectancy has
tended to focus on measures of absolute dierence9092
rather than relative dierence.93 We found unequivocal
divergence in mortality rates for women aged 2539 years
and older than 80 years and for men aged 2044 years and
65 years and older, similar to previous estimates of
divergence of life expectancy at birth since the 1980s.94 In
these age groups, both the Gini coecient and the mean
absolute dierence in death rates are rising. In all other
age groups, except girls aged 1014 years, relative
inequality is increasing but the absolute gap is narrowing.
Framing a grand convergence as simply achieving a
reduction in the dierences in mortality rates across
countries might not be suciently ambitious to meet the
goals of many national policy makers. If mortality
decreases in all countries by the same percent per year,
absolute dierence will decrease and relative dierences
will stay constant. For age groups in which global relative
and absolute dierences in death rates are diverging,
extraordinary eorts will be needed to achieve laudable
goals such as a grand convergence. If convergence
includes reducing the ratio of the highest to lowest death
rates, even for under-5 mortality, major new eorts will be
needed to have faster percent decreases in countries with
higher mortality.
www.thelancet.com Vol 385 January 10, 2015
Interpretation
This study provides a comprehensive description of mortality
levels and patterns worldwide, and provides the evidence to
assess progress of global development goals, including
control of non-communicable diseases, and priorities for
further global health and development debates. Because the
study provides a complete re-analysis of trends for each cause
from 1990 to 2013, it supersedes the results of the GBD 2010
study. This is the rst time that country-specic results for all
188 countries with populations of more than 50 000 people
have been comprehensively published. Country-specic data
provide the opportunity to examine the extent to which
epidemiological convergence is occurring across countries.
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Non-communicable diseases
For the age-standardised death
rates by cause for each country
see http://vizhub.healthdata.
org/cod
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Injuries
Most global road trac deaths occur in low-income and
middle-income countries and are rapidly increasing
because of the growth in motorisation. Mortality rates
caused by trac-related injuries are increasing in
low-income and middle-income countries. Pedestrians
are most often aected, followed by car occupants and
motorcyclists. Conversely, trac deaths are decreasing in
high-income countries. We noted a similar divergence
between low-income and high-income countries for
occupational injuries: they generally fell in high-income
countries (with the exception of deaths resulting from
asbestos-related mesotheliomas), whereas occupational
injury deaths have increased in low-income countries
(data not shown).
Suicide continues to be a major public health problem
in many regions. Half of all suicide deaths occur in
China and India alone. However, the trends are in
opposite directions, decreasing rapidly in China but
rising in India between 1990 and 2013. Both countries
156
India
India accounts for 19% of the worlds deaths in 2013.
Estimations of cause of death for India are important both
for health policy in India and for global understanding of
causes of death. India has had remarkable progress in
reducing both child and adult mortality over the past
23 years. Average yearly rates of decline were 13% per
year for adults and 37% for children.
Unfortunately, less cause of death data were available for
2013 than for 1990 or 2000. The Medical Certication of
Causes of Death system provided ongoing information
about patterns of urban mortality with better completeness
in some states than in others. In rural areas, the Survey of
Causes of Death (Rural) routinely reported causes of death
from verbal autopsy from 1980 to 1998. This survey was
replaced with a verbal autopsy sample collected by the
Registrar-General of India based on the ongoing Sample
Registration Scheme. Data for 200204 have been reported
but not in full detailresults were released in a series of
articles spanning 200814 but even these have not
provided the standard tabulation of deaths by International
Classication of Diseases cause, age, and sex used by
most countries. Verbal autopsies were collected after 2004
but no data have been analysed or released. Attempts to
www.thelancet.com Vol 385 January 10, 2015
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CHERG
GBD 2013
270 (207366)
Diarrhoea
Pneumonia
251 (221291)
50 (17151)
52 (4461)
325 (209470)
213 (186242)
Intrapartum-related complications*
717 (610876)
657 (532770)
Sepsis or meningitis
393 (252552)
369 (237504)
Tetanus
Other neonatal disorders
All causes
58 (20276)
34 (1648)
181 (115284)
470 (411557)
3072
2807 (27192898)
354 (274429)
350 (310394)
Diarrhoea
751 (5381031)
536 (461607)
159 (131185)
102 (95111)
AIDS
Pneumonia
Malaria
1071 (9771176)
772 (693850)
564 (432709)
699 (576855)
Measles
114 (92176)
95 (52166)
Meningitis
180 (136237)
129 (98163)
Other disorders
1356 (11121581)
1355 (12111524)
All causes
4550
4039 (38834207)
Data are thousands of deaths (95% uncertainty interval). GBD=Global Burden of Disease Study. CHERG=Child Health
Epidemiology Reference Group. *Compares GBD cause Neonatal encephalopathy (birth asphyxia/trauma) with
CHERG cause intrapartum-related complications. CHERG did not report uncertainty estimates for all-cause
mortality in children.
Table 5: Comparison of GBD and CHERG estimated child deaths for select causes in 2010
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Conclusion
Global public policy to reduce premature death needs a
detailed, up-to-date, and accurate understanding of
progress (or lack thereof ) of disease and injury control
strategies. This understanding applies not just to
diseases that have been the focus of global public health
eorts for the past few decades, but increasingly, as we
have shown, for newly recognised contributors to global
health trends. Through the process of providing yearly
updates, the GBD is transforming into a collective
approach to global health surveillance. Ideally, it will
aggregate data from all available sources and provide a
coherent view of health levels and trends that is timely,
valid, and local. To fully achieve a collective process of
global health surveillance, the time lag will need to be
shortened between data collection, reporting, and
inclusion in the GBD. Public policy in countries will be
much better informed if more frequent assessments
are accompanied by less uncertainty around the
estimates. Uncertainty will decrease not so much as a
result of further methodological advances in disease
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Mall Leinsalu*, Ricky Leung*, Carly Levitz*, Bin Li*, Yichong Li*,
Yongmei Li*, Chelsea Liddell*, Stephen S Lim*,
Graa Maria Ferreira de Lima*, Maggie L Lind*, Steven E Lipshultz*,
Shiwei Liu*, Yang Liu*, Belinda K Lloyd*, Katherine T Lofgren*,
Giancarlo Logroscino*, Stephanie J London*, Joannie Lortet-Tieulent*,
Paulo A Lotufo*, Robyn M Lucas*, Raimundas Lunevicius*,
Ronan Anthony Lyons*, Stefan Ma*, Vasco Manuel Pedro Machado*,
Michael F MacIntyre*, Mark T Mackay*, Jennifer H MacLachlan*,
Carlos Magis-Rodriguez*, Abbas A Mahdi*, Marek Majdan*,
Reza Malekzadeh*, Srikanth Mangalam*,
Christopher Chabila Mapoma*, Marape Marape*, Wagner Marcenes*,
Christopher Margono*, Guy B Marks*, Melvin Barrientos Marzan*,
Joseph R Masci*, Mohammad Tauq Mashal*, Felix Masiye*,
Amanda J Mason-Jones*, Richard Matzopolous*, Bongani M Mayosi*,
Tasara T Mazorodze*, John J McGrath*, Abigail C McKay*,
Martin McKee*, Abigail McLain*, Peter A Meaney*,
Man Mohan Mehndiratta*, Fabiola Mejia-Rodriguez*,
Yohannes Adama Melaku*, Michele Meltzer*, Ziad A Memish*,
Walter Mendoza*, George A Mensah*, Atte Meretoja*,
Francis A Mhimbira*, Ted R Miller*, Edward J Mills*,
Awoke Misganaw*, Santosh K Mishra*, Charles N Mock*,
Terrie E Mott*, Norlinah Mohamed Ibrahim*,
Karzan Abdulmuhsin Mohammad*, Ali H Mokdad*,
Glen Liddell Mola*, Lorenzo Monasta*, Jonathan de la Cruz Monis*,
Julio C Montaez Hernandez*, Marcella Montico*, Thomas J Montine*,
Meghan D Mooney*, Ami R Moore*, Maziar Moradi-Lakeh*,
Andrew E Moran*, Rintaro Mori*, Joanna Moschandreas*,
Wilkister Nyaora Moturi*, Madeline L Moyer*, Dariush Mozaarian*,
Ulrich O Mueller*, Mitsuru Mukaigawara*, Erin C Mullany*,
Joseph Murray*, Adetoun Mustapha*, Paria Naghavi*, Aliya Naheed*,
Kovin S Naidoo*, Luigi Naldi*, Devina Nand*, Vinay Nangia*,
KM Venkat Narayan*, Denis Nash*, Jamal Nasher*, Chakib Nejjari*,
Robert G Nelson*, Marian Neuhouser*, Sudan Prasad Neupane*,
Polly A Newcomb*, Lori Newman*, Charles R Newton*, Marie Ng*,
Frida Namnyak Ngalesoni*, Grant Nguyen*, Nhung thi Trang Nguyen*,
Muhammad Imran Nisar*, Sandra Nolte*, Ole F Norheim*,
Rosana E Norman*, Bo Norrving*, Luke Nyakarahuka*, Shaun Odell*,
Martin ODonnell*, Takayoshi Ohkubo*, Summer Lockett Ohno*,
Bolajoko O Olusanya*, Saad B Omer*, John Nelson Opio*,
Orish Ebere Orisakwe*, Katrina F Ortblad*, Alberto Ortiz*,
Maria Lourdes K Otayza*, Amanda W Pain*, Jeyaraj D Pandian*,
Carlo Irwin Panelo*, Jeemon Panniyammakal*, Christina Papachristou*,
Angel J Paternina Caicedo*, Scott B Patten*, George C Patton*,
Vinod K Paul*, Boris Pavlin*, Neil Pearce*, Carlos A Pellegrini*,
David M Pereira*, Sophie C Peresson*, Rogelio Perez-Padilla*,
Fernando P Perez-Ruiz*, Norberto Perico*, Aslam Pervaiz*,
Konrad Pesudovs*, Carrie B Peterson*, Max Petzold*, Bryan K Phillips*,
David E Phillips*, Michael R Phillips*, Dietrich Plass*,
Frdric Bernard Piel*, Dan Poenaru*, Suzanne Polinder*,
Svetlana Popova*, Richie G Poulton*, Farshad Pourmalek*,
Dorairaj Prabhakaran*, Dima Qato*, Amado D Quezada*,
D Alex Quistberg*, Felicia Rabito*, Anwar Rafay*, Kazem Rahimi*,
Vafa Rahimi-Movaghar*, Sajjad UR Rahman*, Murugesan Raju*,
Ivo Rakovac*, Saleem M Rana*, Amany Refaat*, Giuseppe Remuzzi*,
Antonio L Ribeiro*, Stefano Ricci*, Patricia M Riccio*, Lee Richardson*,
Jan Hendrik Richardus*, Bayard Roberts*, D Allen Roberts*,
Margaret Robinson*, Anna Roca*, Alina Rodriguez*,
David Rojas-Rueda*, Luca Ronfani*, Robin Room*, Gregory A Roth*,
Dietrich Rothenbacher*, David H Rothstein*, Jane TF Rowley*,
Nobhojit Roy*, George M Ruhago*, Lesley Rushton*,
Sankar Sambandam*, Kjetil Sreide*, Mohammad Yahya Saeedi*,
Sukanta Saha*, Ramesh Sahathevan*, Mohammad Ali Sahraian*,
Berhe Weldearegawi Sahle*, Joshua A Salomon*, Deborah Salvo*,
Genesis May J Samonte*, Uchechukwu Sampson*,
Juan Ramon Sanabria*, Logan Sandar*, Itamar S Santos*,
Maheswar Satpathy*, Monika Sawhney*, Mete Saylan*,
Peter Scarborough*, Ben Schttker*, Jrgen C Schmidt*,
Ione JC Schneider*, Austin E Schumacher*, David C Schwebel*,
James G Scott*, Sadaf G Sepanlou*, Edson E Servan-Mori*,
Katya Shackelford*, Amira Shaheen*, Saeid Shahraz*,
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