Advances in Non-Invasive Saliva

Based Medical Testing Systems

Using Advanced Membranes

ABSTRACT:
The Success of the Personal Fertility Testing and Reproductive
Health System (PFT 1-2-3) and the Future Potential for Saliva
Based Membrane Diagnostic Technology And Substance Abuse
Testing
SUBTITLE: PFT 1-2-3 and Advanced Diagnostic and Drug Testing Devices

PRESENTER:

E. Michael-Porrazzo, Senior Scientist and Vice-President of

Research and Development for Chain Reactions, Inc.; Co-Inventor of PFT
1-2-3® and Advanced Membrane Transducer Technologies, published
author and patent holder.

OVERVIEW OF THE INVENTION:

The Invention of the PFT 1-2-3 Membrane Diagnostic
Device represents a significant
breakthrough for three reasons.

1. First, A successful commercial application for portable,

reusable, inexpensive and accurate use of photonic
activation using membranes to induce crystal growth in
biological fluids for non-invasive medical diagnotistics.
The inventor’s research and development position with the
PFT membrane technology was that the time before
ovulation is where a women is most likely to conceive.

2. Recent medical research appears to validate this position.

It was previously thought that a women’s most fertile time
was at and just after ovulation. Therefore current medical
testing methodologies which analyze LH factor have now
been found to be inappropriate. This is because the surge in
LH occurs at or just after ovulation. More importantly, a
women seeking to avoid conception could easily become
pregnant if she relied upon the results of these kind of

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 medical tests since sperm could
survive well into the most fertile
period, (before ovulation). This is
because the LH medical test
would provide the user with a
positive result just as she had
ovulated. PFT therefore represents
one of the easiest to use, accurate
personal devices for fertility
testing and positive ovulation
detection.

3. The PFT 1-2-3 is able to provide a

wide range of information from the crystalline patterns that are displayed from the Universal
Indices. Universal Indices are the inventor’s discovery which seem to open an entirely new non-
invasive medical diagnostic capability.

4. Third, the use of advanced membranes in products like the PFT may open the future to new kinds
of non-invasive testing products and methodologies, including low cost, reliable and accurate
substance abuse testing systems.

OVERVIEW AND DESCRIPTION OF CAPABILITY:

This technology relates to an advanced membrane health analysis system that is applicable to
both men and women. In particular the device is a portable, hand-held, integrated unit which is
manufactured out of plastic. The unit can be disposable for hygienic purposes, or cleaned or sterilized
for repeated use as desired. The device has numerous aspects. These main aspects include: (1) The
use of any body fluid, but especially saliva to perform the
analysis test upon. (2) The current device is a plastic,
completely integrated, portable, self-contained and self-
focusing Examination System which relies on a visual
reference system making it language independent; (3)
The current device uses a Test Area Section with
replaceable slides where different, specific wavelengths
of light are employed; (4) The embodiment of compound
test areas in the current device allows multiple Tests to
be conducted simultaneously with the capability to
immediately perform two or more Tests simultaneously
using different body fluids or secretions; (5) An
electronic interface device is under development which
can provide a novel battery powered microprocessor
system to automatically perform Testing or Batch
Testing.

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 Current commercial application has provided a highly reliable, low cost, unique, immediate
testing methodology employing any and all female fluids or secretions called Positive Fertility
Testing, “PFT.” The PFT embodiment of the technology provides one of the most accurate
indicators of positive ovulation whereby
a woman may pinpoint times of
greatest fertility, thereby knowing the
optimum time period for achieving or
avoiding pregnancy. Therefore PFT
may be used as a highly effective
method to support birth control. The
PFT may also be used to identify
hormonal imbalances, irregular cycles
or infertility; introduce young women
to their fertility cycle, sexuality and
health.

Another aspect of the

present PFT Invention is that it greatly
simplifies the testing process and results in numerous economies. For instance, unlike many alternative
systems, the PFT does not require a prolonged period of time to perform the analysis, nor are
comparative tests required to get extremely accurate readings. However, the PFT can perform
multiple confirming tests simultaneously by using the same or different female fluid or secretions. In
this way the Invention can immediately provide information on the positive or negative status of a
women’s fertility and the condition of her reproductive health.

The PFT may be used without extensive training. Furthermore, the device and its
associated processes are based upon a visual reference system designed to be language independent
so that it can be used anywhere in the world and in areas where the user may in fact be illiterate.

Because the PFT can tell the user when positive ovulation has occurred it can help a
woman prevent or postpone pregnancy, or assist a woman in becoming pregnant naturally, as desired.
The Invention is accurate during any reproductive situation, including breastfeeding, pre-menopause,
after the discontinuation of medication including, contraceptive pills, and during times of illness or
stress. These are all time which medical research cofirm a women can become pregnant. For women
having difficulty becoming pregnant the PFT can help identify many specific infertility problems
relating to reproductive health.

The PFT can support or reduce the use of other contraceptives and support or reduce
the use of other ovulation test methods. However, the PFT may also be used as a stand-alone birth
control device or reproductive health tool. Other prior art devices are physically invasive, time
consuming, cumbersome and onerous. Traditional prior art devices interrupt or halt intimacy. For
women using the PFT , loving and sexual feelings can flow into spontaneous lovemaking. The PFT
not only avoids the interrupting of lovemaking, but it also eliminates the mess and often harmful side
effects of contraceptive devices and chemicals. The PFT ’s visual display gives information directly
to the woman, thus providing self-confidence, independence and security knowing just when she can
or cannot get pregnant.

Given the President’s mandates regarding the problem of teenage unwed pregnancy in the

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United States and concerns of overpopulation PFT represents a highly effective and reliable
international sex education/awareness tool. Given the high incidence and burdened support costs for
unwed pregnancy in the United States Military and among their dependents the current low-cost PFT
device could be issued to each active duty service man as a preventative measure. It has been
identified that unwanted pregnancy is a
very significant problem in the
United States, with The National
Institute of Health stating that more
than fifty percent of all pregnancies
are unintended. Unintended
pregancy and failure to have proper
fertility awareness education creates
personal stress and a tremendous
financial burden of hundreds of
millions of dollars in support, time
and personnel which depletes
funding resources that could be
channeled to other programs. The
availability of low cost, reusable,
easy to use non-invasive diagnostic
tools like PFT could free up
valuable labor resources and cause
direct cost savings. Deploying PFT
in quantity could allow the
redirection of a significant amount
of funds for other programs.

The PFT can also be a check

step for sexual partners being
untruthful about using birth control
pills or other contraceptives.
Because it is highly portable,
personal and reusable the PFT issued to
women and men would have immediate applicability either to replace or augment existing systems.
The PFT can also be used when and where traditional contraceptive technologies are not available,
cause allergic reactions, or are not used for religious or other reasons.

This non-invasive Membrane Diagnostic Technology may be directly applicable to other

diagnostic capabilities including Saliva Based Membrane Drug and Substance Abuse Testing for
alcohol, marijuana, cocaine, and other illegal substances. Further, the inventors believe that non-
invasive testing methodologies using advanced membrane technologies like the PFT are
fundamentally important to future medical diagnostics.

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DEMONSTRATION
Demonstration of the simplicity of the PFT 1-2-3. Discussion of Medical Tests and Protocol
of Current PFT 1-2-3 Technology. Short 7 minute video may be shown.

Discussion of the commitment needed for future applications of the Saliva Based Membrane
Medical Diagnostic Technology And the potential to create new testing systems for substance abuse
diagnostics.

TECHNICAL CONCEPT:

The PFT is a Saliva Based Membrane

Diagnostic Technology And Testing System and is a
method of diagnosing the fertility status, health
condition of the test subject. The technology employs
an integrated Positive Membrane Testing Apparatus for
both propagating and observing
Universal Indices found in
any human fluids or
secretions, especially saliva, the
method and apparatus comprising a viewing and magnifying area means and
an optically accessible and photonically energized sample collection and
examination area means so that sample(s) of any human fluids or secretions
deposited on the sample collection and examination area means are under
the influence of evaporative processes and the application of light waves
such that crystalline formations of Universal Indices are caused to be
propagated and revealed when observed under viewing and magnifying area
means, thus providing for the qualitative and quantitative diagnosis of
fertility status, health condition and potential levels of substance abuse of the
sample donor. The tests may be self-administered, or administered by
medical personnel.

CURRENT STATE OF DEVELOPMENT:

The Current PFT Membrane technology has been released

commercially since 1/96. The PFT devices are now available in any quantity
for immediate deployment. Qualified educational personnel are at hand to
train designated personnel. Training video, literature and multi-media
material are available. PFT is being evaluated by various agencies including,
NASA, US Army, NRAD, NIH, AAFES, among others.

Contact Information: Michael Porrazzo, CTO of MODDHA-Porrazzo,

808.298.6508 email: m@moddha.com

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