West Visayas State University

COLLEGE OF NURSING
La Paz, Iloilo City

DRUG STUDY
Name of Patient:
Age:
Name of Drug
Generic:

Attending Physician:
Impression/Diagnosis:

Ward/Bed Number:
Dosage,
Route,
Frequency
and Timing
Dosage:

Hyoscine
Route:
Brand:
Buscopan
Frequency:

Timing:

Mechanisms of
Action

Indication

Inhibits action of
acetylcholine at
postganglionic
(muscarinic)
receptor sites.
Therapeutic
Effect: Decreases
secretions
(bronchial,
salivary, sweat
gland,
gastric juices).
Reduces motility
of GI,
urinary tracts.Well
absorbed
following PO
administration.
Protein binding:
50%. Metabolized
in
liver. Majority
excreted in urine.
Removed

PO: Adjunctive
therapy for
peptic ulcer
disease, irritable
bowel
syndrome,
neurogenic
bladder or
bowel;
treatment of
infantile
colic, GI tract
disorders
caused by
spasm,
hypermotility of
lower urinary
tract;
reduce
abdominal
rigidity; reduce
tremors
associated with
Parkinsons

Adverse
Reactions

Special
Precautions

Nursing Responsibilities

Overdose may
produce
temporary
paralysis
of ciliary muscle,
pupillary dilation,
tachycardia,
palpitations,
hot/dry/flushed
skin, absence of
bowel sounds,
hyperthermia,
increased
respiratory rate,
EKG
abnormalities,
nausea,
vomiting; rash
over face/upper
trunk, CNS
stimulation,
psychosis
(agitation,
restlessness,
rambling

Give before
meals.
Immediate
release
tablets may be
crushed,
chewed.
Extendedrelease tablet
should be
swallowed
whole.
Allow orallydisintegrating
tablet placed on
tongue to
dissolve
before
swallowing; may
give with or
without water.
Sublingual:
Place under
tongue.

Before giving medication,

instruct pt to void (reduces
risk of urinary retention).
Monitor daily pattern of
bowel activity, stool
consistency.
Palpate bladder for
urinary retention.
Monitor changes in B/P,
temperature.
Assess skin turgor, mucous
membranes to evaluate
hydration
status (encourage
adequate fluid
intake),
bowel sounds for peristalsis.
Be alert for fever (increased
risk of hyperthermia).
May cause dry mouth;
maintain good oral hygiene
habits (lack of saliva may
increaserisk of cavities).
Inform physician
of rash, eye pain, difficulty

by hemodialysis.

Classification
Functional:
Antimuscarinic,
antispasmodic.
Chemical:
Anticholinergic

disease; drying
agent in acute
rhinitis.

Contraindication
s
GI/GU
obstruction,
myasthenia
gravis, narrowangle glaucoma,
paralytic ileus,
severe
ulcerative
colitis. Cautions:
Hyperthyroidism
, CHF, cardiac
arrhythmias,
prostatic
hypertrophy,
neuropathy,
chronic lung
disease,
biliary tract
disease.

speech, visual
hallucinations,
paranoid
behavior,
delusions)
followed by
depression.

Side Effects
Frequent: Dry
mouth
(sometimes
severe),
decreased
diaphoresis,
constipation.
Occasional:
Blurred vision,
bloated feeling,
urinary
hesitancy,
drowsiness (with
high
dosage),
headache,
intolerance to
light,
loss of taste,
anxiety, flushing,
insomnia,
impotence,
mental confusion
or excitement
(particularly in
elderly, children),
temporary light-

in urinating, constipation.
Avoid tasks that
require alertness, motor skills
until response to drug is
established

headedness
(with parenteral
form), local
irritation (with
parenteral
form). Rare:
Dizziness,
faintness

Students Name:
Clinical Instructor: