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3 SWEDISH-HELLENIC
LIFE SCIENCE RESEARCH CONFERENCE
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25–27 March 2010

Athens, Greece

Conference Venue:
National Hellenic Research Foundation
48 Vassileos Constantinou Ave.
Athens, Greece

Hosted by:
National Hellenic Research Foundation
(NHRF)

Conference Organisers:
• Fragiskos Kolisis, Professor
NHRF, Greece.
E-mail: kolisis@eie.gr
• Nikolaos Venizelos, Assoc. Professor
Örebro University, Sweden.
E-mail: nikolaos.venizelos@oru.se
3rd Swedish-Hellenic Life Science Research Conference
Organized by:

 National Hellenic Research Foundation (NHRF)

1. Institute of Biological Research & Biotechnology (IBRB)
2. Institute of Organic & Pharmaceutical Chemistry (IOPC)
3. Theoretical & Physical Chemistry Institute (TPCI)

 Örebro University:
1. School of Health and Medical Sciences, Division of Clinical Medicine
2. School of Science and Technology, Örebro Life Science Centre (ÖLSC)

Örebro University Organizing Committee:

 Allan Sirsjö, Professor, School of Health and Medical Sciences, Division of Clinical
Medicine.
 Jana Jass, Assoc. Professor, School of Science and Technology, ÖLSC
 Per-Erik Olsson, Professor, Vice-Dean, Faculty of Business, Science and Engineering

Local Organizing Committee:

 Dr. Niki Chondrogianni, Institute of Biological Research & Biotechnology
 Dr. Maria Skreta, Deputy Director, Institute of Organic & Pharmaceutical Chemistry
 Dr. E.I. Kamitsos Director, Theoretical & Physical Chemistry Institute

Information:
National Hellenic Research Foundation Örebro University:
48 Vassileos Constantinou Ave. School of Health and Medical Sciences
11635 Athens, Greece School of Science and Technology, ÖLSC
Tel. +30 210 7273700 (switchboard) 701 82 Örebro, Sweden, 019-30 30 00(switchboard)
Official conference language: English
Certificate of Attendance: Available after registration and conference attendance

THE NEW ACROPOLIS MUSEUM IN ATHENS

 3

3rd Swedish-Hellenic Life Science Research Conference

24-27 Mars 2010, Athens, Greece
PROGRAMME
Thursday, 25 March 2010
Time Title of presentation Speaker

09.30-12.00 National Commemoration Day of Greece Parade at Sydagma Square

Posters to be placed on poster boards
11.00–13.00 Entrance hall of NHRF
(Poster's dimension: 120 (high) x 80 cm (width)
13.00-13.55 Registration Entrance hall of NHRF
F. Kolisis and N. Venizelos
14.00-14.05 Welcome Chairs of the conference organizing
committee

Prof. Dimitrios Kyriakidis

14.05-14.15
President of NHRF

Assoc. Prof. Jana Jass

14.15-14.20 Conference opening and Plenary lecture Chair of the Örebro Life Science Centre
14.20-14.25
Prof. Robert Brummer
Dean of Faculty of Medicine and
Health, Örebro University, Sweden
Prof. Robert Brummer
14.25-15.00 Microbes and the ‘Gut-Brain Axis’ Dean of Faculty of Medicine and
Health, Örebro University, Sweden
15.00-15.15 Break*
Chair: Prof. Per-Erik Olsson/Dr. Michalis Alexis
Prof. Godfried Roomans
Correcting the chloride transport abnormality in the airway
15.15-15.45 School of Health and Medical Sciences,
epithelium of cystic fibrosis patients
Örebro University, Sweden
Dr. Fay Oikonomou
BRAFV600E an Hsp90 Client, as a Sensitizer to TRAIL-
15.45-16.05 Institute of Biological Research and
Induced Apoptosis in Human Colon Cancer Cells
Biotechnology, NHRF
DNA methylation of the p14ARF, RASSF1A and APC1A
Prof. Torbjörn Nilsson
genes define a poor prognosis subset of colorectal cancer
16.05-16.30 Dept. of Laboratory Medicine, Örebro
patients independently of tumor stage and tumor
University Hospital
differentiation
Dr. Vassilis L Souliotis
Cellular DNA damage-response following exposure to
16.30-16.50 Institute of Biological Research and
therapeutic drugs. The case of multiple myeloma
Biotechnology, NHRF
Researcher Ingrid Lindh
16.50-17.15 Plant produced vaccine antigens with special emphasis School of Science and Technology,
on HIV Örebro Life Science Center
Dr. Spyros Zographos Institute of
Structure-Based Drug design: A approach to Drug
17.15-17.35 Organic and Pharmaceutical Chemistry,
Discovery
NHRF
Chair: Dr. Soterios Kyrtopoulos/Prof. Elisabeth
Hultgren-Hörnquist
17.45–19.15 Poster session Poster nr 1 to 24
19.20-19.30 Presentation of the best nominate Poster (10 min) (Presenters must be at their Posters)

19.30- Dinner Foyer of NHRF

*Coffee and sandwiches can be purchased at the bar by the Entrance hall of NHRF
 4

Friday, 26 March 2010

Time Title of presentation Speaker

Chair: Prof. F. Kolisis/Assoc. Prof. N. Venizelos

Prof. Demetrios Thanos
Chairman, Biomedical Research
09.00-09.45 Stochastic mechanisms of gene expression Foundations of The Academy of
Athens, Adjust Prof. of Columbia
University
Dr. Ioannis Talianidis
Director of The Institute of Molecular
09.45-10.25 Transcription regulation in liver
Biology, BSRC "A. Fleming", Vari,
Greece
Pyrosequencing assay of the UCP3 -55C>T polymorphism: Researcher Lovisa Olsson
10.25-10.45 effects on plasma homocysteine and academic achievments in Dept. of Laboratory Medicine, Örebro
Children and Adolescens University Hospital, Sweden
Mechanistic research to support the study of the Dr. Soterios Kyrtopoulos
10.45-11.15 environmental causes of disease Institute of Biological Research and
Biotechnology, NHRF
Dr. Niki Chondrogianni
11.15-11.35 The proteasome as a target in anti-aging Institute of Biological Research and
Biotechnology, NHRF
Researcher Hazem Khalaf
11.35-12.00 Environmental influences on inflammatory responses School of Science and Technology,
Örebro Life Science Center, Sweden
12.00-13.00 Break*

Chair: Prof. Allan Sirsjö / Dr. E. Kamitsos

Assoc. Prof. Eva Särndahl
The Inflammasome - in surveillance of immune homeostasis
13.05-13.30 School of Health and Medical
and development of severe inflammatory disease
Sciences, Örebro University.Sweden
Dr. Dimitra Mitsiou
Genome-wide analysis of glucocorticoid receptor targets:
13.30-13.50 Institute of Biological Research and
relevance to inflammation
Biotechnology, NHRF
Assist. Prof. Nikolai Scherbak
Probiotic Lactobacillus effects on the urogenital tract: A
13.50-14.15 School of Science and Technology,
quest for the mechanism of action
Örebro Life Science Center; Sweden
Prof. Torbjörn Bengtsson
The role and mechanism of platelet interaction with bacteria
14.15-14.40 School of Health and Medical
in cardiovascular disease
Sciences, Örebro University,Sweden
Dr. Nikos Tagmatarchis
Carbon nanotube-based hybrid materials for medicinal
14.40-15.15 Theoretical and Physical Chemistry
applications
Institute, NHRF
15.15-15.30 Break*

Chair: Dr. E. Kamitsos/ Assoc. Prof. Jana Jass

Career advice regarding Post-doc in EU countries: The National Documentation Centre
15.30-16.15 How to apply for grants, availability and short scientific (NDC), National Contact Points’
exchanges programmes. Network etc.
How to write and submit a paper for publication:
J.G. Delinassios
16.15-17.00 Important criteria in writing/submitting a paper, what
Editor of IN VIVO journal
editors/reviewers look for and common mistakes.
Chair: Assoc. Prof. Jana Jass / Dr. Maria Skretas
17.10-19.00 Poster session Poster nr 25 to 48
19.05-19.15 Presentation of the best nominate Poster (10 min) (Presenters must be at their Posters)
Kostis Palamas
19.30 Dinner (Academy Club University of Athens)
*Coffee and sandwiches can be purchased at the bar by the Entrance hall of NHRF
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SSA
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URRD
DAAY
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ARRC
CHH 2277
Programme for the participants from Örebro University
Bus: Ilisia Hotel 07:30 to Acropolis Museum at 8.00 a.m.
General admission fee: 5 Euros (tickets available from the Ticket Desk at Museum)
Bus: 09:30 at Mitseon Street (entrance for groups). Excursion/meeting to Porto Germano
Bus: 23:00 from Porto Germano to Athens, 24:15 at Hotel Ilisia

LIST OF POSTER PRESENTATIONS

Information concerning posters
The chairs of the poster sessions will appoint two posters as the best posters of the conference (one for each poster session). The
winners will give a 10 min oral presentation. Therefore, all presenters have to be prepared for a 10 min oral presentation (3 ppt
pictures) at the auditorium. Poster's dimension: 120 (high) x 80 cm (width).

Presenter Poster Number and Title Affiliation

Jessica Johansson
Jessica Johansson
Meropi Patrinou-
Georgoula
Meropi Patrinou-
Georgoula
Ioannis Bantounas
Berolla Sahdo
Avgi Tsolou
Marcus Nordén
Stella Logotheti
Ola Westman
Pelagia Koukouraki
School of Health and Medical
1. Aberrant amino acid transport in patients with bipolar
Sciences, Dept. of Clinical
type-1 disorder
Medicine, Sweden
School of Health and Medical
2. Aberrant amino acid transport in children with Attention-
Sciences, Dept. of Clinical
deficit/hyperactivity disorder (ADHD)
Medicine, Sweden
Institute of Biological Research
3. Interactive Partners and Molecular Characteristics of the
and Biotechnology, NHRF,
mammalian hnRNP A3 Protein
Athens, Greece
4. Deregulated expression of hnRNP A/B proteins in Institute of Biological Research
human non-small cell lung cancer: correlation of protein and Biotechnology, MHRF ,
and mRNA levels in paired tumor /non-tumor tissues Athens, Greece
Institute of Biological Research
5. MicroRNAs and Their Role in the Regulation of Gene
and Biotechnology, NHRF,
Expression in Cancer
Athens, Greece
School of Health and Medical
6. S. aureus pore-forming toxins activates the
Sciences, Dept. of Clinical
inflammasome
Medicine, Sweden
Institute of Biological Research
7. Role of 19S Proteasome subunits in DNA damage and
and Biotechnology, NHRF,
stress-induced premature senescence
Athens, Greece
School of Science and
8. Gene expression analysis of chicken during development
Technology, MTM Research
subsequent to PFOS and PFOA exposure
Center, Sweden
Institute of Biological Research
9. Sp1 binds the external promoter of p73 Gene and induces
and Biotechnology, NHRF,
the expression of Tap73 γ isoform in lung cancer
Athens, Greece
10. Effects of perfluorinated compounds on hepatic fatty School of Science and
acid oxidation in avian embryos using a tritium release Technology, MTM Research
assay Center, Sweden
11. Phycocyanin and Phycocyanobilin from Spirulina as
Potential Photosensitizers for Photodynamic Therapy. Institute of Biological Research
Interactions with Biological Phosphates studied by and Biotechnology, NHRF,
UV/Vis Spectrophotometry Athens, Greece

12. Functional studies of a mitochondrial protein found to be School of Health and Medical
Marike Gabrielsson Sciences, Dept. of Clinical
frequently inactivated in breast cancer.
Medicine, Sweden
13. A large-scale European study reveals the role of genetic Institute of Biological Research
Konstantinos
and environmental factors on healthy aging and and Biotechnology, NHRF,
Voutetakis
longevity Athens, Greece
 6

Presenter Poster Number and Title Affiliation

School of Health and Medical
Breezy Paul 14. Loss of mitochondrial solute carrier SLC25A43- a
Sciences, Dept. of Clinical
Malakkaran common event in HER2 positive breast cancer
Medicine, Sweden

15. Global and gene-specific histone methylation pattern in Institute of Biological Research
Angelo Ferraro and Biotechnology, NHRF,
colorectal carcinoma cells.
Athens, Greece
School of Health and Medical
16. mRNA expression levels of ENaC subunits in airway
Rashida Hussain Sciences, Dept. of Clinical
epithelial cell lines and nasal epithelia
Medicine, Sweden
17. Cloning and functional studies of a splice variant of School of Health and Medical
Ali Elmabsout CYP26B1: A cellular storage protein for all-trans Sciences, Dept. of Clinical
Retinoic ACID Medicine, Sweden

18. Chlamydophila pneumoniae induce platelet activation by School of Health and Medical
Hanna Kälvegren binding to Toll-like receptor 2- role in cardiovascular Sciences, Dept. of Clinical
disease Medicine, Sweden

19. Oncogenic mutations in KRAS and BRAF and their Institute of Biological Research
Vivian Kosmidou implication in TRAIL receptor expression in colorectal and Biotechnology, NHRF,
tumours Athens, Greece

20. Differential Effect of Oncogenes BRAF and RAS on Institute of Biological Research
Eleni Makrodouli Rhomediated induction of EMT properties in Human and Biotechnology, NHRF,
colon cancer cells Athens, Greece

21. Released substances from lactobacilli influence immune School of Science and
Mattias Karlsson
responses in human epithelial cells Technology, ÖLSC, Sweden

School of Health and Medical

Geena Paramel 22. Association between polymorphism in the CARD8 gene
Sciences, Dept. of Clinical
Varghese and myocardial infarct in men
Medicine, Sweden
23. Development and validation of a quantitative, PCR-
Institute of Biological Research
based assay for the measurement of platinum DNA
Demetra Stefanou and Biotechnology, NHRF,
damage formation/repair in ovarian carcinoma. Clinical
Athens, Greece
application
24. Tissue specific expression of heat shock factor 5 in School of Science and
Eirini Tsiapali
zebrafish Technology, ÖLSC, Sweden
Institute of Biological Research
25. A compartmented in silico model of Rapeseed central
Eleftherios Pilalis and Biotechnology, NHRF,
metabolism
Athens, Greece
26. An in vitro inflammation model of human bladder School of Science and
Hanan Abuabaid
epithelial cells and macrophage co-cultures Technology, ÖLSC, Sweden

Institute of Biological Research

27. The role of estrogen receptor (ER) β1 and ERβ2 in ERα-
Νiki Chantzi and Biotechnology, NHRF,
negative breast carcinoma
Athens, Greece

28. TAF4b and AP-1 in co-regulation of Cancer Cell Institute of Biological Research
Margarita
Migration Properties and expression of Integrin α6 and Biotechnology, NHRF,
Kalogeropoulou
during Epithelial to Mesenchymal Transition Athens, Greece

School of Health and Medical

Ashok Kumar 29. Phenotypical and functional characterization of T
Sciences, Dept. of Clinical
Kumawat lymphocytes in Microscopic colitis.
Medicine, Sweden
Institute of Organic and
Spyros E. Zographos
30. Structural Studies of hCINAP: Αn atypical mammalian Pharmaceutical Chemistry
nuclear adenylate kinase with ATPase activity NHRF, Athens, Greece
 7

Presenter Poster Number and Title Affiliation

School of Health and Medical
31. Effect of interleukin-1beta on tyrosine uptake in
Shahida Hussain Sciences, Dept. of Clinical
fibroblasts of schizophrenic patients and healthy controls
Medicine, Sweden
School of Science and
Ahmed El Marghani 32. TOM1L is involved in the IL-1 signaling in THP-1 cells
Technology, ÖLSC, Sweden
Institute of Biological Research
33. Olive oil-based w/o nano-emulsions: a novel biomimetic
Aris Xenakis and Biotechnology, NHRF,
system for studying oxidative enzymatic reactions
Athens, Greece

34. Modeling of the ERα LBD in Complex with Antagonists School of Science and
Li Gao
and Related Torsional Isomerization of Tamoxifen Technology, ÖLSC, Sweden

Institute of Biological Research

35. Enzymatic esterifications using lipase from Rhizomucor
Maria Zoubanioti and Biotechnology, NHRF,
miehei immobilized onto silica matrix
Athens, Greece
Institute of Biological Research
Varvara Trachana
36. The implication of the ubiquitin-proteasome system in and Biotechnology, NHRF,
the early onset of ageing Athens, Greece
37. Repair of melphalan adducts shows a general 5’ to 3’-end Institute of Biological Research
Episkopou HG and Biotechnology, NHRF,
gradient effect in transcribed genes. Clinical implications
Athens, Greece
38. Covalent binding of act to DNA through a bis-functional Institute of Biological Research
Panagiotis Georgiadis agent and its possible implication to human and Biotechnology, NHRF,
carcinogenesis Athens, Greece
39. O6-Methylguanine levels in maternal and cord blood
Institute of Biological Research
leukocyte DNA and their relationship with maternal
Panagiotis Georgiadis and Biotechnology, NHRF,
dietary intake of N-nitroso compounds and related
Athens, Greece
precursors
Institute of Biological Research
40. Validation of a new immunochemical assay with high-
Panagiotis Georgiadis and Biotechnology, NHRF,
throughput potential for PAH-DNA adduct detection
Athens, Greece

41. Estrogen receptor beta iosforms 1 and 2 differentially Institute of Biological Research
Ageliki Meligova modulate growth and invasiveness of breast cancer cells and Biotechnology, NHRF,
in response to estrogen and antiestrogens Athens, Greece

42. Bioinformatic Analysis of Mastic Oil Treatment in Institute of Biological Research

Panagiotis Moulos Different Tumor Cell Lines Reveals Molecular and Biotechnology, NHRF,
Mechanisms Targeting Cell Growth and Survival Athens, Greece

43. Transcriptomic Computational Analysis of the Cell Institute of Biological Research

Panagiotis Moulos Death Induced by N-Methyl-N-Nitrosourea, a Model Sn1 and Biotechnology, NHRF,
Methylating Agent, in Human Lung Cancer Cells. Athens, Greece
School of Health and Medical
44. Hepatocyte growth factor in patients with coronary artery
Johanna Lönn Sciences, Dept. of Clinical
disease: a biomarker for evaluation of the disease state?
Medicine, Sweden
45. Regulation of PS2, CCND1 & IEX-1 genes in HER2- Institute of Biological Research
Xanthipi Alexi overexpressing breast cancer cells: correlation with and Biotechnology, NHRF,
tamoxifen resistance Athens, Greece
46. Involvement of zebrafish Ff1a in the development of School of Science and
Jarno Koskinen
pharyngeal arches Technology, ÖLSC, Sweden
School of Health and Medical
47. Microbe-Gut Interaction in Microscopic Colitis and Post-
Johanna Sundin Sciences, Dept. of Clinical
Infectious Irritable Bowel Syndrome (IBS)
Medicine, Sweden
Institute of Biological Research
48. CHIP overrides Mdm2-mediated degradation of p53
Christina Sisoula and Biotechnology, NHRF,
during replicative senescence
Athens, Greece