Académique Documents
Professionnel Documents
Culture Documents
Aurelia Nicoleta Cristea, Tratat de Farmacologie, sub redactia, Ed. Medicala, Bucuresti, 2005
***Farmacopeea Romana, editia a X-a, Ed. Medicala, Bucuresti, 1993
Ordinul Ministrului Sntii Nr. 75/2010 cu privire la Regulile de bun
practic farmaceutic, Monitorul
Oficial al Romaniei, partea I, nr. 91/2010.13. Marius Bojita, Liviu Roman, Robert Sandulescu, Radu Oprean,
Analiza si Controlul Medicamentelor, vol. 1si 2, Ed. Interlcredo, Cluj-Napoca, 2002.14. Martian Cotrau, Teodor
Stan, Lidia Popa, I. Preda, Maria Kincsez-Ajtay, Toxicologie, Ed. Didactica siPedagogica, Bucuresti, 1991.15. Ion
Ciulei, Emanoil Grigorescu, Ursula Stanescu, Plante medicinale, fitochimie si fitoterapie, Ed.Medicala, Bucuresti,
1993.16. .
Aurelia Nicoleta Cristea, Farmacie Clinic, volumul I, Editura Medical, Bucureti 2006
Leucuta S., Biofarmacie si farmacocinetica, Editura Dacia, Cluj-Napoca, 2001.
"Vitamin B6 (Pyridoxine) deficiency may lead to anemia, depression, dermatitis, high blood
pressure (hypertension), water retention, and elevated levels of homocysteine."
http://en.wikipedia.org/wiki/B_vitamins#B_vitamins_deficiency
Those who do not take Vitamin suplements, do not get enough B Vitamins:
quote ".... only a fraction of U.S. adults currently get the recommended daily intake of all B
vitamins by diet alone" -Harvard.eduhttp://www.hsph.harvard.edu/nutritionsource/whatshould-you-eat/vitamin-b/index.html#bottom-line
Dr Shari Lieberman and Dr Andrew Weil both concur that the "recommended daily intake"
RDI (or older RDA) will keep you "Alive but Not Happy" Most people are not even getting
the RDI or RDA needed for survival. Dr Shari Lieberman's "Real Vitamin and Mineral Book"
suggests the Optimum dose for B Vitamins as 25mg to 300 mg daily. Andrew Weil MD
suggests 50mg/day for his brand http://www.drweil.com/drw/u/ART02763/vitaminb6.html (Medical staff with stressful jobs sometimes take up to 1000 mg of B Complex /day, I
used to but now more like 600 mg/day). ALSO: get a separate B-12 (in mcg not mg) at least
1000 mcg per day, I get at least 10,000 mcg /day of B-12 (mental physical coordination and
well being). Vitamin List RDI/RDA & Dr Shari Liebermans "Optimum daily
intake"http://www.archure.net/salus/vitamins.html So get a multivitamin and get a "B
Complex" or "B Stress Formula" or "B-100" in the 100 mg size, and get 25 to 300 mg per day
(600 up to 1000 mg is ok for an adult, but not 2000 mg daily), weight proportion for children,
good for happy children daily, good for better grades, and plenty in pre-natal vitamins
already
LACK OF B VITAMINS CAUSES DEPRESSION: quote "DON'T WORRY, B HAPPY: If your seriously
low on any of the B vitamins, depression is one of the earliest symptoms. In fact, studies
show....over three-quarters of all depressed patients have a pyridoxine (vitamin B-6)
deficiency. Giving these patients even small doses of pyridoxine (vitamin B-6) improves their
depression" - pg 54 "Idiots Guide to Vitamins & Minerals" by Alan H. Pressman, D.C., Ph.D.,
C.C.N. This page http://archure.net/salus/bhappy.html
VITAMIN
MINERAL
MINIMUM
B1 thiamin
1.5 mg
25 - 300 mg
none
B2 riboflavin
1.7 mg
25 - 300 mg
none
B3 niacin
20 mg
25 - 300 mg
3,200 mg
B6 pyridoxine : )
2 mg
25 - 300 mg
>2,000 mg
B12 cobalamin
6 mcg
25 - 300 mcg
none
BIOTIN
300 mcg
300 mcg
Choline/Inostiol
n/a
25 - 500 mg
FOLIC acid
400 mcg
PABA
n/a
25 - 500 mg
??
PANTOTHENIC
acid
10 mg
25 - 500 mg
http://archure.net/salus/vitamins.html
Most people don't take vitamins, most people are depressed (and hide it)
20% to 30% of people take vitamins "Daily" ///// 50 % to 80% never take
vitamins http://www.crnusa.org/benpdfs/CRN011benefits_whovms.pdf
!! Vitamin and Mineral Safety 3rd Edition by John N. Hathcock, Ph.D. with a
foreword by James C. Griffiths, Ph.D. edited by Douglas MacKay, N.D. Andrea Wong,
Ph.D. Haiuyen Nguyen
Even those who take a multi vitamin (good to do) do not get enough B vitamins to keep
them happy, as the official RDI is enough to keep you alive but not
happyhttp://en.wikipedia.org/wiki/Reference_Daily_Intake
Question:
Can taking too much vitamin B-12 be dangerous? The label on my B-complex states it contains
50,000% the Daily Value!
Answer:
If your B-complex contains 50,000% of the Daily Value (DV), which is 6 mcg for adults, then it has 3,000
mcg of B-12. For people without a severe B-12 deficiency, this is certainly more than necessary.
Taking some B-12 is advisable for people over the age of 50 (when you're less able to extract B-12 from
food), as well as for those taking medications that interfere with B-12 absorption, strict vegetarians,
alcohol and drug abusers, people recovering from surgery or burns, and those with bowel or pancreatic
cancer.
Although vitamin B-12 is generally considered to be safe, and no "Upper Tolerable Intake Level" has been
established, there are some reports of doses of 20 mcg per day or higher causing outbreaks of acne and
rosacea. There is also a study which showed that a high-dose B complex supplement (with 1,000 mcg of
B-12) hurt, rather than helped, people with diabetes and advanced kidney disease.
In general, it's best to avoid excessive doses of any vitamin if it is not needed.
Get more information, including the Recommended Daily Allowance for B-12 (by age and gender),
differences in the forms of B-12, potential side-effects and drug interactions, plus ConsumerLab.com's
tests of popular products, in the B Vitamin Supplements Review >>
https://www.consumerlab.com/answers/Can+taking+too+much+vitamin+B12+be+dangerous%3F+The+label+on+my+Bcomplex+states+it+contains+50,000%25+the+Daily+Value!+/too_much_b12/
Current DV1
UL2
Vitamin A
5,000 IU
Vitamin C
60 mg
2000 mg
Calcium
1,000 mg
2,000 mga
Iron
18 mg
45 mg
Vitamin D
400 IU
Vitamin E
30 IU
1000 mg
Vitamin K
80 mcg
ND
Thiamin
1.5 mg
ND
Riboflavin
1.7 mg
ND
Niacin
20 mg
35 mg
Vitamin B6
2 mg
100 mg
Folate
400 mcg
1,000 mcg
Vitamin B12
6 mcg
ND
Biotin
300 mcg
ND
Pantothenic acid
10 mg
ND
Phosphorus
1,000 mg
4g
Iodine
150 mcg
1,100 mcg
Magnesium
400 mg
Zinc
15 mg
40 mg
Selenium
70 mcg
400 mcg
Copper
2 mg
10,000 mcg
Manganese
2 mg
11 mg
Chromium
120 mcg
ND
Molybdenum
75 mcg
2,000 mcg
Chloride
3,400 mg
3.6 g
The table lists the Daily Values (DVs) based on a caloric intake of 2,000 calories, for adults and children four or
more years of age. The nutrients in the table above are listed in the order in which they are required to appear on a
dietary supplement label. This list includes only those nutrients for which a DRV has been established.
2
The Tolerable Upper Intake Level (UL) is the highest level of daily nutrient intake that is likely to pose no risk of
adverse health effects to almost all individuals in the general population. The UL values listed above pertain to adult
( 19 y) men and women, excluding pregnant and/or lactating women
a
The UL for calcium is 2,500 mg for men and women 19-50 y and 2,000 mg for those individuals 51 y.
ND = not determined
http://www.crnusa.org/about_recs.html