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Negative Feedback mechanism of blood pressure Person in shock Blood volume incre
ase Baroreceptor less stimulated increase rate of impulses to medulla oblongata
that send impulses to effector 1. Cardiac muscle & smooth muscle relax 2. Blood
flow resistance decrease 3. Heart beat rate decrease 4. Vasodilation occurs ( wi
dening of blood vessel) Blood pressure decrease
Person injured or do vigorous exercise Blood volume decrease Baroreceptor stimul
ated - decrease rate of impulses to medulla oblongata that send impulses to effe
ctor 1. Cardiac muscle & smooth muscle contract 2. Blood flow resistance increas
e 3. Heart beat rate increase 4. Vasoconstriction occurs (narrowing of blood ves
sel) Blood pressure increase
Insects (open circulatory system) Vessels site of chemical exchange Haemocoel co
nsist haemolymph Heart (1 or more) pump heamolymph into vessel Ostia open when h
eart relax to allow heamolymph to flow through (consist valve) close when heart
contract Fish ( single circuit closed circulatory system) 1. Blood leave the ven
tricle to gill capillaries, gaseous exchange occur, then flow into a vessel to s
ystemic capillaries. Carbon dioxide diffuse out & oxygen diffuse in to blood the
n return to atrium through vein Amphibians (double circuit closed circulatory sy
stem) 1. Oxygenated blood from lung& skin enter left atrium, Deoxygenated blood
from body enter right atrium. Both atria contract & push blood to a ventricle. 2
. Ventricles contract & pump mixed blood to pulmocutaneous circulation (lung & s
kin) & systemic circulation (body). Mammal & Bird (double circuit closed circula
tory system) 1. Oxygenated blood from lungs enter left atrium, Deoxygenated bloo
d from body enter right atrium. Both atria contract & push blood to ventricles,
then contract & pump oxygenated blood to systemic circulation via aorta & deoxyg
enated blood to pulmonary circulation via pulmonary arteries Blood does not mixincrease blood pressure & speed up delivery of oxygen to body. Mechanism of blo
od clotting 1. When blood vessel damaged, platelets exposed to collegen fibres &
release clotting factors that cause the platelet sticky & release thromboplasti
n to convert prothrombin to thrombin with calcium & vitamin K. Thrombin act as e
nzyme to convert fibrinogen to fibrin that form sticky net of fibres & traps red
blood cell. Heparin chemical that inhibits clot formation Joshua Chong Kah Leon
g 2012 Copyright is reserved for sharing & individual purpose
Stimulus : Change that trigger body responses Response : Reaction towards a stim
ulus Coordination : regulation of body activities Internal Stimuli : Blood osmot
ic pressure & glucose level External Stimuli : Light, temperature, touch, pressu
re & sound Chapter 2. Pathway of nerve transmission Stimulus is detected by rece
ptors & send impulses along afferent neurons to integrating centre for analysis,
then send impulses along efferent pathway to effector for response. Negative fe
edback corrective mechanism in opposite direction of environment change
Nervous system
Central Nervous System - proses, analyse & store information & start response
Peripheral Nervous System - relay signals between CNS & body parts
Autonomic nervous System Brain - Primary integration organ Spinal Cord - control
reflex action - connect brain & PNS - conduct impulses to & from the brain Symp
athetic System - prepare for activity ( Spinal Nerve) - control involuntary acti
on - has motor parts (efferent neurons & effector)
Somatic Nervous System - control voluntary action - has sensory & moror parts
Parasympathetic System - prepare for relazation ( 12 Carnial & 31 Spinal Nerve)
Human Brain Cerebrum Cerebellum Thalamus Hypothalamus Pituitary Gland Medulla Ob
longata Spinal Cord Central Canal Grey Matter White Matter Ventral root Dorsal r
oot Spinal nerve
- control voluntary action, memory & intelligence ( action, hearing & tasting) left side control right body movement & vise-versa - control body balance & mov
ement - give awareness of touch, pain & temperature (sense) - control homeostasi
s, blood pressure, body temperature, sleep & thirst - Produce hormones & control
growth, reproduction & osmoregulation - control involuntary action, act as refl
ex centre
- contains cerebrospinal fluid ( supply nutrient & act as shock absorber) - main
tain electrolyte balance in CNS - contain neurons & dendrites - contains myelincoated axons of neurons that surrounds grey matter - contain efferent neurons &
conduct impulses from spinal cord to effector - contain afferent neurons & condu
ct impulses from receptor to spinal cord - Ganglion ( place afferent neurons clu
stered) - contain ventral & dorsal roots
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Neurons Dendron / Dendrites Cell body Axon Synaptic terminal Myelin sheath
- conduct impulses - provide large surface area to receive information - integra
te electrical signals & coordinate metabolic activities - transmits impulses fro
m cell body to synaptic terminal - transmits impulses from neurons to effector o
r other neurons - speed up the impulses transmission & protect axons Interneuron
s - from afferent to efferent neurons - Grey matter - CNS ( not myelinated) Effe
rent neurons -from CNS to effector - Grey matter - whole body
Impulses Cell Body Location
Afferent neurons - from receptor to CNS - Dorsal root ganglion - whole body
Transmission of Information across synapses Impulses form presynaptic neurons st
imulate synaptic vesicles to release neurotransmitter into synaptic cleft/ synap
se & diffuse to dendrite of post-synaptic neurons that excites to produce impuls
es
-Converts electrical > chemical > electrical Signal, contain mitochondria (gener
ate energy for transmission)
Function of synapse 1. control & integrate impulses 2. ensure impulses transmiss
ion in one direction Voluntary action under control of will Cerebral cortex of c
erebrum Fast or Slow aware action is taken Skeletal muscles Involuntary action N
ot under control of will Medulla Oblongata & hypothalamus Fast unaware action is
taken Skeletal muscles & Gland
Characteristic CNS Reaction Awareness Effector
Reflexes - involuntary response to stimulus (rapid & automatic) Importance : 1.
Protect body from danger 2. Coordinate muscular function 3. Act as automatic res
ponse 4. Provide response before feeling pain Reflex Arc - nerve pathway that pr
oduce reflex action
Knee-jerk reflex / Patella reflex - Knee tendon is tapped by rubber hammer. Quad
riceps muscle stretched & send impulses along afferent neurons to spinal cord &
back to efferent neurons to then cause the leg jerk forward.
Burns cause receptors to send impulses along afferent neurons to spinal cord for
analysis, then relayed to interneurons & sent along efferent neurons to effecto
r. Cause triceps relax & biceps contracts to pull hand away.
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Function: - coenzyme for carbohydrates, protein & fats metabolism - red blood ce
ll formation Deficiency disease: Anaemia & Diarrhoea
Vitamin B12 Function: tissu
e & red blood cell formation Deficiency disease: Anaemia
Vitamin C Function: Hea
lthy skin & healing of wounds, as antioxidant Deficiency disease: Scurvy
Vitamin
D/ Calcium/ flourine Function: Strong bones & teeth. Deficiency disease: Ricket
s (Soft / deformed bones)
Vitamin E Function: - tissue & red blood cell formatio
n, - as antioxidant - prevent sterility
Vitamin K Function: Help in blood clotti
ng Deficiency disease: Anaemia
4. Bolus move down the oesophagus by peristalsis Stomach 1. Gastric Gland secret
e gastic juice : - Pepsin digest protein into polypeptides - Rennin coagulates m
ilk & digest caseinogen into casein - hydrochloride acid stop salivay amylase ac
tivity, kill bacteria & provide acidic medium for rennin & pepsin Duodenum 1. Pa
ncreas secrete pancreatic juice: (Start absorption) - Pancreatic amylase digest
starch, trypsin digest polypeptides, Lipase digest lipid droplets 2. Bile produc
ed by liver & stored by gall bladder: - emulsify lipid into lipid droplets Ileum
(complete 1. Intestinal gland secrete intestinal juice absorption) - digest suc
rose, lactose & maltose, peptides, lipid * Digestion of albumen Peristalsis spon
taneous contraction & relaxation of alimentary tube Digestion of Cellulose in Hu
man, Ruminants & Rodents Similarities 1. Consume plant & digest starch, fats & p
rotein 2. Digestive system with stomach, small & large intestine 3. Contain symb
iotic bacteria ( protozoa ) to secrete cellulase Differences Human Omnivores Sin
gle stomach chamber Small caecum No protozoa no chewing cud & regurgitate food d
oes no re-ingest faeces Food Digestion Problem Indigestion (Incomplete food dige
stion) - eat too much oily food - eat too fast Ruminanats Herbivores & Omnivores
Single stomach chamber Long & well-developed caecum Protozoa in caecum no chewi
ng cud & regurgitate food re-ingest faeces Specific enzyme production decrease damage of digestive glands - diabetes mellitus & genetic factors Rodents Herbiv
ores Four Small caecum stomach chamber Big & not well-developed caecum Protozoa
in rumen have chewing cud& regurgitate food no re-ingest faeces does Formation o
f gallstone (blocked bile duct) - eat too much fatty food - obesity
Structure of Small Intestine in Relation to Absorption 1. Villi absorbed most nu
trient in the ileum, 4. Absorption in epithelial cell factors: Amino acid & gluc
ose facilitated transport - folded walls to increase total surface area fatty ac
id & glycerol simple diffusion - having very thin walled ( one cell thick ) Wate
r Osmosis - having a network of blood capillaries Mineral & Vitamin simple diffu
sion & active - Having lacteals for absorption of fatty acid & transport glycero
l 2. Intestinal crypt make epithelial cell - secrete lysozyme & intestinal juice
(alkaline fluid & mucus) to increase fluid volume in gut - goblet cell secrete
mucus
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3. Lacteals / lymphatic vessel - absorb glycerol, fatty acids & fat soluble vita
mins (ADEK) then transport via lymphatic system to bloodstream 4. Blood capillar
ies from villi merge to form hepatic portal vein which transport nutrient to liv
er Liver store & convert glucose in glycogen & amino acid into urea & flow proce
ssed nutrient into hepatic vein Assimilation - absorption of digested product by
body cell Fats & lipid Amino acids - stored by adipose tissue - Excess - underg
oes deamination into (keep body warm & stored urea energy, protect body) - gluco
se shortage -converted into - oxidise to generate energy glucose - build plasma
membrane & - help on blood clotting cholesterol - growth & repair damaged tissue
- synthesis enzyme & hormones
Glucose - excess converted into glycogen & stored in liver -shortage glycogen co
nverted back into glucose - used in cellular respiration
Function of liver - maintain blood glucose level by secretion of insulin & gluca
gon - maintain body temperature - manufacture bile, plasma protein (fibrinogen &
prothrombin )& haemoglobin - store vitamin fat soluble vitamin & nutrient - det
oxification of poisonous substances - deamination of amino acid - synthesis of v
itamin A for blood clotting Formation of Faeces - water, vitamin & salt from und
igested food are absorbed by colon - mucus to lubricates movement of faeces alon
g colon - Beneficial synthesis vitamin K & B12, produce antibiotic to kill patho
genic & digest nutrient fragments Constipation Colon Cancer Haemorrhoids faeces
hard & slow in passing due cause by prolonged constipation & Veins around anus i
nflamed & too large amount water loss toxic accumulated in colon swollen Prevent
ed by eat more roughage & drink more water & often exercise Defecation Dischargi
ng of faeces from large intestine through anus Importance 1. Excrete waste & tox
ic substances 2. Avoid toxicity & poisoning in body Gastritis Inflammation of st
omach lining Irregular meal time, too much alcohol & smoking Pain in abdomen Obe
sity Excessive body fats above than a normal weight Eat too much fatty food Lack
of exercise High risk of high blood pressure, diabetes mellitus & heart attack
Anorexia Nervosa Eating disorder by consuming food minimally Low self-esteem bel
ieve themselves to be fat, extremely thin, dont want to eat. Bulimia Nervosa Eati
ng disorder by consuming food excessively Depression, misuse of laxatives Over c
oncern with body weight, eat a lot and force themselves to vomit
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2. Catalysed by enzyme & involve chemical reaction Factors Carbon dioxide concen
tration photosynthesis rate increase as carbon dioxide concentration increase up
to a certain point where light intensity & temperature became the limiting fact
ors Light Intensity Photosynthesis rate is increase as light intensity increase
to a certain point where carbon dioxide & temperature became the limiting factor
s Temperature Photosynthesis dark reaction is catalysed by photosynthetic enzyme
Optimum temperature 25-300C the Temperature too high destroy the enzyme and pho
tosynthesis stops.
Ways to improve food production Direct seeding seed sown directly into soil Hydr
oponics Aeroponics Breeding Tissue Culture Genetic Engineering Soil management B
iological control growing in aerated culture solution suspended in air with root
sprayed with nutrient Dura sp & Pisifera sp = Tenera Sp ( Thick mesophyll, smal
l shell & Big kernel) grow in culture medium Manipulating DNA to produce organis
m with new characteristic Reduce soil erosion & leaching
Save cost, labour & time, increase the yield Better quality & quantity, Save spa
ce Better quality & quantity, Save space high nutritional value, higher yield &
pest resistance Better quantity & same quality as parent x Enhance growth & nutr
itional properties 1. Add fertilizer consistently 2. ploughing to increase soil
aeration 3. Practice crop rotation- improve soil fertility control pest & reduce
pesticides usage
natural prey-predator relation
Importance of Food Processing 1. Food can last longer 2. Prevent spread of disea
se 3. increase fodd commercial value 4. Avoid food wastage Ways (Food additives)
Food preservation, food enhancers, food colouring Cooking Caning Drying Ferment
ation Sugar or Salt pickling Pasteurisation Refrigeration Ultra Heat Treatment H
igh temperature kill bacteria High temperature kill bacteria, vacuum prevent bac
teria growth Water removed from bacteria, sunlight kill bacteria Ethanol remove
water from bacteria & kill bacteria create hypotonic solution to remove water fr
om bacteria by osmosis High temperature kill bacteria, maintain milk taste (720C
-15sec, 630C-30 min, then 50C) Low temperature prevent bacteria growth High temp
erature kill bacteria (1320C-1sec)
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Fish Adaptation of gills: a) Thin lamella membrane - allow fast & effective gase
ous exchange b) Rich of blood capillaries maximise gaseous exchange c) Surrounde
d by water enable respiratory gases to be dissolve d) Large surface area of fila
ments & lamellae maximise gaseous exchange Countercurrent mechanism 1. Deoxygena
ted blood flows in opposite direction of water current through blood capillaries
in the lamellae, encounters higher O2 content water, concentration gradient all
ows the O2 diffuse into the blood 2. When CO2 concemtration in blood is higher t
han in water, CO2 diffused from blood into water
Breathing mechanism 1. Buccal cavity lowered to decrease buccal cavity pressure
2. Water drawn flow into mouth & through lamellae. 3. Oxygen diffuse from water
to lamellae & carbon dioxide diffuse from lamellae to water. 3. Mouth closed & b
uccal cavity raised to increase buccal cavity pressure causing operculum to open
& water to flow out.
Adaptation of Alveoli 1. large number of alveoli - increase surface area for gas
eous exchange 2. One cell thick walls fast & effective gaseous exchange 3. Moist
( wall secrete moisture) fast & effective gaseous exchange 4. Surrounded by blo
od capillaries network maximise gaseous exchange Inhalation External intercostal
muscles contract Internal intercostal muscles relax Rib cage move upwards and o
utwards Diaphragm contracts and flattens Volume of thoracic cavity increase resu
lting in low air pressure in thoracic air cavity Higher atmospheric pressure cau
ses air to flow in Transport of Oxygen Partial oxygen pressure in alveoli higher
than in blood capillary, oxygen diffuses into blood capillary. Oxygen combine w
ith heamoglobin to form oxyheamoglobin Partial oxygen pressure in blood capillar
y higher than in body tissue. Oxyheamoglobin release oxygen that difuses into bo
dy tissue Exhalation External intercostal muscles relax Internal intercostal mus
cles contract Rib cage move downwards and inwards Diaphragm relaxes and returns
to dome-shaped Volume of thoracic cavity decrease resulting in highair pressure
in thoracic air cavity Low atmospheric pressure causes internal air to flow out
Transport of carbon dioxide Partial carbon dioxide pressure in blood capillary l
ower than in body tissue, carbon dioxide diffuses into blood alveoli.Carbon diox
ide 1. dissolved in blood plasma as bicarbonate ions (70%) 2. combines with heam
oglobin to form carbaminoheamoglobin 3. dissolved in blood plasma Partial carbon
dioxide pressure in alveoli lower than in blood capillary. Carbaminoheamoglobin
release carbon dioxide that difuses into alveoli
Regulation respiration mechanism 1. During vigorous exercise, muscles require mo
re O2 and glucose to release energy during cellular respiration, 2. Rate of resp
iration increase, rate of breathing increase, heartbeat increase, 3. More O2 and
glucose can be supplied for cellular respiration and more CO2 removed from the
cells.
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4. Rate of gaseous exchange between alveoli and blood capillaries increase Regul
ation Mechanism of Carbon Dioxide Content 1. During vigorous exercise, more carb
on dioxide produced, blood pH decrease, detect by chemoreceptors in medulla oblo
ngata that sent impulses to intercostal muscle to contract & relax rapidly, brea
thing rate increase, more carbon dioxide eliminated, carbon dioxide concentratio
n & blood pH return to normal Regulation Mechanism of Oxygen Content 1. At high
altitude/Fear, oxygen concentration decrease, detect by chemoreceptors in caroti
ds & aortic bodies that sent impulses to intercostal muscle & diaphragm to contr
act. Breathing rate increase, heartbeat increase, more oxygen inhaled oxygen con
centration level return to normal Good habits to cultivate healthy respiration s
ystem 1. practice healthy diet & breathing exercise 2. do not smoke & avoids bre
athing polluted air Respiration in plant In mitochondrion for cellular respirati
on Photosynthesis light to chemical energy CO2 & H2o is used, glucose & oxygen i
s formed Water decomposed Presence of sunlight Store glucose Involve chloroplast
Chlorophyll pigment needed In green plant only
Respiration chemical to light energy glucose & oxygen is used, CO2 & H2O is form
ed Glucose decomposed All condition Used glucose Involve mitochondrion Chlorophy
ll pigment not needed In all organism
Photosynthesis rate is highest in midday (large amout of CO2 is formed) Respirat
ion rate is highest in midnight (large amout of CO2 is used) Compesation point n
o net exchange of oxygen & carbon dioxide (CO2 is formed = CO2 is used), Photosy
nthesis rate = Respiration rate Plant carries out anaerobic respiration during f
lood & initial stages of germination
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3. Parasitism - one organism benefits from the host a) Ectoparasites feed on the
surface of the host(e.g. ticks and fleas) b) Endoparasites shelter & feed on tis
sue in the host (e.g. tapeworms) Prey-predator An animal is haunted & eaten by a
stronger animal - regulate both organisms populations Saprophytism An organism
lives and feeds on decaying organic matter. Saprophytes (plant) - mushrooms, brea
d mould and bracket fungus. Saprozoites (bacteria) - paramecium sp & amoeba sp Co
mpetition - two organisms to obtain limited basic needs of life living space, wa
ter, minerals, sunlight, food and mates. a) Intraspecific completion ( between s
ame species) b) Interspecific competition (between different species ) colonizat
ion a process where life take place & form a colony in a newly formed area succes
sion - a process where dominant plant replaced by another plant in a habitat (sl
ow & continuous) 1) pioneer species dense root systems- to survive on dry & nutr
ient-poor soil. change habitat into more suitable habitat for another species to
live. 2) dominant species - Grow faster to out-compete pioneers - occurs in sta
ges until stable & matured community equilibrium with environment is formed. (cl
imax community) Colonisation and Succession in a Mangrove Swamp Environmental co
nditions : a) Soft muddy soil b) Waterlogged soil which lacks oxygen c) Seawater
with high salinity (high salt content) d) Strong sunlight & extreme heat. a) Av
icennia sp. (open area)& Sonneratia sp.(shaddy area) - pioneer species - pneumat
ophores (Breathing roots with spongy tissue) - enable respiration of roots & pro
vide support - viviparous seedlings geminate while attached to mother plant, flo
at on water & ensure species survival Joshua Chong Kah Leong 2012 Copyright is r
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Genus name (capital) followed by species name ( small letter) Biodiversity Speci
es Population Community Ecosystem Niche Habitat a diverse species of plants & an
imals interacting with one another a group of organism with similar characterist
ic living in the same habitat a group of organism of same species living in the
same habitat at the same time Several population of different species living in
the same habitat in an ecosystem A community of organism interact together & wit
h natural environment Role of an organism environment where organism live
Microorganism - microscopic organisms that cannot be seen by naked eye. Protozoa
sexual & asexual reproduction through cell division, have cilia, pseudopodium &
flagella Fungi visible to naked eye, sexual & asexual reproduction through spor
e formation & budding Bacteria asexual reproduction through binary fission & spo
re formation, visible under light microscope Algae have cell wall made of cellul
ose, have chlorophyll, reproduce through fermentation & spore (Protista) formati
on, Virus smallest microorganism, visible under electron microscope, infest on l
iving cell for nutrition & (Monera) respiration & reproduction. Have protein coa
t & form spore Nitrogen cycle To maintain balance of nitrogen content in the wat
er, soil & atmosphere. a) Nitrogen fixation( conversion of atmospheric nitrogen
is to nitrogen compounds required for growth) Nitrogen fixing bacteria (Nostoe s
p & Rhizobium sp) in root nodules convert atmospheric nitrogen into ammonium com
pounds that converted into plant protein, become animal protein when eaten by an
imal b) Decomposition, Nitrification &Denitrification 1. When the animals and pl
ants die, nitrifying bacteria, convert dead organism & waste matter into nitrite
s(Nitrosomonas sp.) & nitrates(by Nitrobacter sp.). 2. Denitrifying bacteria con
vert nitrates into atmospheric nitrogen & complete the nitrogen cycle Lightning
energy causes oxygen combine with nitrogen to form nitrogen oxide. Combine with
rain drops to form nitric acid, then combines with the soil minerals to form nit
rates & nitrites. Decomposition Saprophytes (putrefying bacteria & fungi) digest
protein in dead organism into ammonium compounds. & nutrient released in the so
il Alimentary canal of termites Protozoa (Trichonympha sp). in alimentary canals
termites secretes the cellulase & enables termite digest cellulose in wood Dige
stive system in humans a) Symbiotic bacteria in colon (caecum) synthesis vitamin
B12 (anaemia) and vitamin K. (blot clotting) Joshua Chong Kah Leong 2012 Copyri
ght is reserved for sharing & individual purpose
Methylene blue solution decolourise when presence of oxygen in water is low Defo
restation Important of rainforest - Permanent removal of trees from forest 1. Ha
bitat of flora & fauna Effect 2. Provide food & 1. soil erosion & landslide medi
cine 2. flash flood 3. Regulate world climate 3. global warming & climax change
4. Water catchment area 4. destroy natural habitat, extinction of species 5. des
troy recreation area
Mining decrease soil nutrient , hydroelectric dam flash flood Burning of fossil
fuel - release carbon dioxide, sulphur dioxide & nitrogen oxide pollute air & ca
use acid rain
Bad Agricultural pratices 1. Use excessive inorganic fertilisers &pesticides 2.
intensive farming Effect 1. pollute water source 2. cause eutrophication & flash
flood 3. Soil structure changed
Air pollution condition where pollutant enter air from various source - cause ha
ze (decrease light penetration, affect photosynthesis) - cause acid rain corrode
s buildings, soil & water acidity increase, leeching of soil nutrient, affect pl
ant growth & cause health problems Water pollution condition where pollutant ent
er water from various source Thermal pollution increasing environmental temperat
ure due to excess heat release Noise pollution unwanted man-made sound disrupts
environment & people health & welfare - factors : aeroplanes, machinery vehicles
, factories machines, piling & drilling in construction area - cause deafness, h
igh blood pressure & headache A) Biological control Method where predator is use
d to control the population of that pest in an area. use prey-predator interacti
on. a) Does not pollute environment (stop use of pesticides.) b) Does not kill o
ther organisms c) Is cheap and safe to use B) Enforcement of Environment Quality
Act - prevent environmental pollution by control licensing & examines disposal
of waste & smoke in industry C) Education - raise awareness & importance of prot
ect healthy environment for society , recycle & less polluting D) Preservation &
Conservation of ecosystem - replant trees after deforestation, restore mining l
and for agricultural, river cleaning, treat toxic & waste before disposal, use u
nleaded petrol, E) Use of renewable energy Joshua Chong Kah Leong 2012 Copyright
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