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PASTEUR INSTITUTE

Veterinary Products
2003

Large animal biologicals


Poultry biologicals
Small animal biologicals
Pharmaceuticals
Diagnostic biological reagents
Small animal accesories
Index

LARGE ANIMAL
BIOLOGICALS

1. AGAVAC

22. PESTRUVAC

2. ANATET

23. PNEUMOSUIVAC

3. ANTRAVAC

24. POLIMASTIVAC

4. AUVAC

25. RABIVAC E

5. BIPAST B

26. RINOVAC B

6. BIVIRAL B

27. ROMPERVAC ABCD

7. BVD - MD - VAC

28. ROMPERVAC AC

8. COLISER B

29. RUVAC

9. COLISER P

30. SALMOVAC Sm 237

10. COLIVAC P

31. SALMOVIN

11. DISER

32. SEPTIVAC

12. ECVIPARVAC

33. SEROGAN

13. EMFIVAC

34. SEROGAN AC

14. ERINVAC

35. SERVIPAST

15. IBR - IPV VAC

36. SUIGET

16. LEPTOVAC

37. SUIGET VIU

17. MAMIVAC

38. SUIPASTVAC

18. MYCOVAC

39. TESER

19. OVIPARVAC

40. TETRAVAC B

20. PARAMYCOVAC

41. TRICOVAC

21. PESTIVAC

42. TRIVIRAL B

POULTRY BIOLOGICALS
1. BIAVAC

9. ND - GUMBOINVAC

2. BRONVAC

10. ND - SINCO - GUMBOINVAC

3. COLUMBO - DIV

11. ND - SINCOVAC

4. COLUMBOVAC

12. NEDEVAC

5. DI - COL

13. NEWVAC LA SOTA

6. DI - GAL

14. NEWVAC LS79

7. GUMBOINVAC

15. SINCOVAC

8. LARINGOVAC

16. TETRAINVAC

SMALL ANIMAL
BIOLOGICALS

1. HEMORAGIVAC

4. PENTACAN

2. LEPTOCANIVAC

5. RABIVAC E

3. PARVOCAN

6. TRIVIROCAN

PHARMACEUTICALS
1. ACETOSTOP
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.

AD3E
AMINOPHENAZONE
AMINOVIT
AMOXAN 40
AMPICILLIN 100
AMPICILLIN 250
ANEMIN P
ANTIMYCOTIC
OINTMENT
ASCOMICIN
AVOMEC
BRONHOSTIM
CAFFEINE - SODIUM
BENZOATE 25%
CALCIUM
BOROGLUCONATE
CALCIUM MAGNESIUM
CANIDER U

17. CLORODIN U
18. CLOROSTATIC
19. COCCISTOP S
20. DEO VET
21. DERMOSEPT
22. DEXOGEN
23. DIAZINOL

36. ENROFLOXACIN 10%


37.
38.
39.
40.
41.
42.
43.
44.

ENROFLOXACIN 25
ENROFLOXACIN 50
EQVAMEC P
EVOMEC
FENAZON
FTALIPEPS 50 mg
FTALIPEPS 250 mg
GENTAMYCIN 5%

45.
46.
47.
48.

GENTAMYCIN 10%
GENTAMYCIN 10%
GENTOCIN DOSER
GENTOCIN
OPHTHALMIC
49. GENTOCIN OTIC

50. GERMOSTOP
ANTIMASTITIS
51. GERMOSTOP BUCCAL
52. GERMOSTOP
DERMATOLOGICAL
53. GERMOSTOP FOR
MEDICAL
INSTRUMENTS
54. GERMOSTOP FOR THE
UDDER
55. GERMOSTOP
HEXASOL SCRUB
56. GERMOSTOP
HEXASOL SURGICAL
57. GERMOSTOP L
58. GERMOSTOP P

24. DIGESTIM
25.
26.
27.
28.
29.

59. GERMOSTOP
SHAMPOO
60. GLUCOSE 10%
61. GLUCOSE 33%
62. HELMIZOL A 2.5
63. HELMIZOL A 10
64. HELMIX

33. ENROFLOXACIN 5%
34. ENROFLOXACIN 5
35. ENROFLOXACIN 10%

65. INDOMETHACIN
66. IODINE TINCTURE
67. IODOFORMED ETHER 5
%
68. IOD - POVIDONA 10%
69. IVER - MITE OTIC
70. IVER - MIX

DIZENTER
ECTOCANIGAL
ECVIPAST
ECVIPAST N
EFFERVESCENT AND
FOAMING PESSARIES
WITH NEOMYCIN AND
OXYTETRACYCLINE
30. ENERGOSOL
31. ENROBACT
32. ENROFLOXACIN 2.5%

71. LINCOMYCIN 4.4%

113. PHYSIOLOGIC SALINE

72.
73.
74.
75.

114.
115.
116.
117.

LINCOMYCIN 11%
LINCOMYCIN 100
LINCOMYCIN 200
LINCOMYCIN SPECTINOMYCIN 2.2%

PILOCARPINE
PRAZYTEL
PREMIX E-150
PRO - CAL

76. LINCOMYCIN SPECTINOMYCIN 4.4%

118. PROLIZ

77. LINCOVET 10
78. LIN - SPE - MIX 22
79. MAGNESIUM
SULPHATE
80. MASTIKER E
81. MEDIODINE SCRUB
82. MEDIODINE SOLUTION

119. PRO - VITE


120. PRURITAK
121. PYRATEL CD
122. PYRATEL EQ
123. PYRATEL PREMIX
124. REHIDRASOL

83. METHIONINE
84. METHYLENE BLUE 1%

125. REHIDRAVIT
126. ROSTODERM

85. MICOCID
86. MICODERMIN

127. SCABATOX
128. SINGAL 5 mg

87.
88.
89.
90.
91.

MICOVIT
MITE EMULSION
NEOBACITRACIN
NEOHEXIDIN
NEO - MINE - VIT P

129.
130.
131.
132.
133.

92. NEOMYCIN SULPHATE


10 %
93. NEOTYL
94. OCULIN N
95. OPTI - CLOR
96. OTOSTATIC
97. OTOSTOP N
98. OTTO-CLEANS

135.
136.
137.
138.
139.
140.

99. OVIZOL 300

141.

100.
101.
102.
103.
104.
105.
106.
107.
108.
109.
110.
111.
112.

OXICOR 5%
OXIPAN
OXIRET 20%
OXYTETRACYCLINE
OXYTETRACYCLINE
10%
OXYTETRACYCLINE
20%
OXYTETRACYCLINE
20%
OXYTETRACYCLINE
HYDROCHLORIDE
PASTAZOL 25 mg
PASTAZOL 100 mg
PASTIGAL T
PEN STREP
PET - SPRAY

SODIUM IODIDE
STRESSIN
SULFASEPT
SULFATYL 100
SUPER KILLER 25 EC

134. TETRACYCLINE 100

142.
143.
144.
145.
146.

TETRACYCLINE 250
TILOMETRIN
TRICHINOSTOP
TYLAROM 50
TYLAROM 200
VAGINAL
OXYTETRACYCLINE
AND NEOMYCIN
SUPPOSITORIES
VAGINAL
OXYTETRACYCLINE
SUPPOSITORIES
VALBAZEN 2.5%
VALBAZEN 10%
VAMEX
VERMIZOL A 10
VERMIZOL A 50

147. VERMIZOL A 100


148. VETASED
149. VITAMIN AD3E
150.
151.
152.
153.
154.

VITAMIN B1 5 %
VITAMIN B1 + B6
VITAMIN B6 5 %
VITAMIN C 10%
VITAMIN K3

DIAGNOSTIC
BIOLOGICAL REAGENTS
1. ALEXIN

15. GAMAROM IFD - PPC

2. AVISAR

16. HAEMAGGLUTININ PI3

3. BROVSET

17. HAEMOLYSIN

4. BRUCEFIX

18. HEMORAGITEST

5. BRUCELINA B

19. ID - SPECITEST B

6. BRUCELINA P

20. ID - SPECITEST C

7. BRUCEROBEN

21. ID - SPECITEST P

8. BRUCEROCAN

22. LEPTOSER

9. BRUCETIL

23. MALLEIN

10. CHLAMYDIOFIX

24. MORVOSET

11. ELIBRUCELLA

25. PARAMYCOSET

12. ELITRICH

26. PARATUBERCULIN

13. ENZOOTIC BOVINE


LEUCOSIS KIT

27. TUBERCULIN A

14. EQUINE INFECTIOUS


ANAEMIA KIT

28. TUBERCULIN B

SMALL ANIMAL
ACCESSORIES

1. E&Z FIT MUZZLE FOR DOGS &


CATS
2. HAPPY SBFP
3. HAPPY SG
4. HAPPY SP
5. LEASHES COLLARS

AGAVAC
INACTIVATED VACCINE AGAINST SHEEP
AND GOAT CONTAGIOUS AGALACTIA

COMPOSITION
Formalin- and heat-inactivated, and aluminium hydroxide-adsorbed
Mycoplasma agalactiae.
INDICATIONS
Preventive and emergency purposes in the sheep and goat contagious
agalactia, vaccination being applied during the second half of gestation.
ADMINISTRATION AND DOSAGE
Subcutaneously behind the elbow or at the tail basis, at 1 ml irrespective
of the animal age or size.
Revaccination is applied 20-30 days later at the same dose.
CONTRAINDICATIONS
Diseased animals, those under stress and during the last gestation month.
POSTVACCINAL REACTIONS
An oedema may occur at the inoculation site; it disappears 24-48 hours
later leaving behind a small, persistent nodule. Drops in the milk
production may be recorded during the first days post the emergency
vaccination of lactating ewes; the milk yield reverts to normal after 2-3
days.
Under the current practice conditions, the inoculation of certain vaccines
may induce, irrespective of the manufacturer, anaphylactic reactions to
some animals. The animals should be observed for 1-2 hours post
vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 20, 50, 100 or 250 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ANATET
TETANUS ANATOXIN

COMPOSITION
Formalin- and head-inactivated, and aluminium hydroxide-adsorbed
Clostridium tetani toxin.
INDICATIONS
Prophylactically: Healthy animals for a sound, long-lasting immunity.
Curatively: During the first disease stage in association with the tetanus
antiserum.
ADMINISTRATION AND DOSAGE
Both preventively and curatively, by the subcutaneous route as follows:
Large animals
Inoculation I: 10 ml.
Inoculation II, 30 days later: 10 ml.
Inoculation III, 1 year later: 10 ml.
Small animals
Inoculation I: 5 ml.
Inoculation II, 30 days later: 5 ml.
Inoculation III, 1 year later: 5 ml.
POSTVACCINAL REACTIONS
A local inflammatory reaction, under the form of a nodule, develops that
resorbs within a few days leaving behind a tissue induration.
Under the conditions of current practice, the inoculation of some vaccines
may induce, irrespective of the manufacturer, occasional anaphylactic
reactions to some animals. The animals should be observed for 1-2 hours
post vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light and freezing.
PACKAGING
Bottle of 5 or 10 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ANTRAVAC
CONCENTRATED ANTHRAX VACCINE

COMPOSITION
Spores of Bacillus anthracis, strain 1190 R in a glycerin- and saponinadded excipient.
INDICATIONS
Prevention of anthrax in all sensitive species. Vaccination is usually
applied in spring, 14-21 days before turnout.
ADMINISTRATION AND DOSAGE
Subcutaneously, at a single dose (one vaccination) as follows:
Sheep, pigs, 2 months up: 0.2 ml (1 dose)
Cattle, 2 months up: 0.5 ml (2.5 doses)
Horses, 6 months up: 0.2 ml (1 dose)
Goats, 2 months up: 0.1 ml (0.5 dose)
CONTRAINDICATIONS
Animals below the age indicated for each species.
Febrile animals.
During the last gestational month and the first weeks post parturition.
5 days after the antiparasitic dipping of sheep or 5 days before and after their
shearing.
The vaccination against pasteurellosis, black leg, anaerobioses,
gangrenous mastitis, salmonellosis or colibacillosis should be applied 21
days before the one against anthrax, not simultaneously.
POSTVACCINAL REACTIONS
Slight oedemata may occur at the inoculation site and/or slight drops in
the milk yield (cattle, sheep, goats) that revert to normal within 2-3 days.
Should persistent 10-20 cm oedemata occur at the inoculation site, the
animals are kept inside and cold compresses are applied. In case
oedemata larger than 20 cm develop and the animals are febrile, these
are to be treated with penicillin or other antibiotics to which B. anthracis is
sensitive.
Under the current practice conditions, the inoculation of certain vaccines
may induce, irrespective of the manufacturer, anaphylactic reactions to
some animals. The animals should be observed for 1-2 hours post
vaccination; if necessary, an antihistaminic will be administered.
PRECAUTIONS
The milk from febrile animals is to be boiled before consumption.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 5, 50 or 100 doses.
MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

AUVAC
VACCINE AGAINST PIG AUJESZKYS DISEASE
(freeze-dried)

COMPOSITION
Attenuated Aujeszkys disease virus, strain Bucureti grown on hen
embryo fibroblasts or on the established cell line PK15.
INDICATIONS
Preventive purposes
Selection farms
: Breeding boars and sows: Twice a year, during
trimesters
II and IV.
: Young animals: At 55-65 days of age, with a booster after
21-28 days.
Breeding and large scale farms supplying biological material for
reproduction: Young boars and gilts before delivery: Twice, 21 days
apart; the last vaccination will be applied 14 days before delivery or
transfer.
Emergency purposes
Following the slaughter of the animals with clinical signs of Aujeszkys
disease, all the herd sucklers starting with 3 days of age included in
the contaminated houses and the animals under imminent contamination
risk should be vaccinated.
The piglets born to the sows vaccinated and then boostered 14 days at
least before farrowing will be vaccinated 3-5 days before weaning, and
then boostered 21-28 days later.
With the other animal categories the vaccination is repeated after 21-28
days.
Immunity is maintained by a single administration every 6 months by large
groups of swine for 2-3 years.
ADMINISTRATION AND DOSAGE
The vaccinal dose is, irrespective of age, 1 ml inoculated by the
intramuscular route.
The booster is at the same dose. The vaccine vial should be shaken
before filling each syringe.
The vaccination may be concomitant with the one against classical swine
fever, yet administered at separate sites.
CONTRAINDICATIONS
No other species but swine.
The animals in herds where highly diffusible infectious and contagious
diseases are present.
POSTVACCINAL REACTIONS
No reactions occur irrespective of the age of administration.
STORAGE
At 2-8oC, protected from light and freezing.
PACKAGING
Vial of 50 vaccinal doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BIPAST B
INACTIVATED BIVALENT VACCINE
AGAINST PASTEURELLA-INDUCED
BRONCHOPNEUMONIA OF YOUNG CATTLE

COMPOSITION
Formalin- and heat-inactivated, and aluminium hydroxyde-adsorbed
Pasteurella multocida and Pasteurella haemolytica.
INDICATIONS
Preventively, to control bronchopneumonia in young cattle.
ADMINISTRATION AND DOSAGE
4 ml are subcutaneously inoculated, with booster after 21 days, starting
with 15 days of age.
The maintenance vaccination is every 6 months at a single dose of 4 ml.
CONTRAINDICATIONS
Calves below 15 days of age.
Less than 15 days post the administration of the serum against
Pasteurella.
Calves diseased with bronchopneumonia, or febrile ones.
Should clinical signs of bronchopneumonia occur before vaccination II,
revaccination will be postponed until the animals recover based on the
treatments applied.
POSTVACCINAL REACTIONS
Local ones: An oedematious or hard nodule variable in diameter may
occur that resorbs in time.
Systemic ones: Sometimes dyspnoea, hypersalivation, diarrhoea occur
that are remitted after 24 hours.
Under the conditions of current practice, the inoculation of some vaccines
may induce, irrespective of the manufacturer, occasional anaphylactic
reactions to some animals. The animals should be observed for 1-2 hours
post vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 25 or 60 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BIVIRAL B
MODIFIED LIVE VACCINE AGAINST INFECTIOUS BOVINE
RHINOTRACHEITIS-INFECTIOUS PUSTULAR VULVOVAGINITIS
AND TYPE 3 PARAINFLUENZA (freeze-dried)

COMPOSITION
Infectious bovine rhinotracheitis virus, strain Oxford and type 3
parainfluenza virus, strain Cs-291 grown on calf kidney cell cultures.
INDICATIONS
Calves, young cattle: Prevention and control of respiratory conditions of
viral aetiology.
ADMINISTRATION AND DOSAGE
Preventive purposes
It is administered at 2 ml by the intramuscular route to calves starting
with the age of 2-3 weeks, with booster by the same route at the same
dose 15 days later.
It may also be administered by the nasal route to calves starting with the
first days of life at 2 ml (1 ml into each nostril), with booster at the same
dose by the intramuscular route 15 days later.
Emergency purposes
2 ml are administered intramuscularly, the concentration of the viral
mass/dose being however double.
CONTRAINDICATIONS
Breeders.
Farms providing reproduction animals.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 5, 10 or 20 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BVD - MD - VAC
MODIFIED LIVE VACCINE AGAINST BOVINE
VIRAL DIARRHOEA-MUCOSAL DISEASE
(freeze-dried)

COMPOSITION
Bovine viral diarrhoea-mucosal disease virus, strain IL-396 grown on calf
kidney or testicular cell cultures.
INDICATIONS
Prevention of the diarrhoea, abortions and respiratory conditions induced
by the infection with the bovine viral diarrhoea-mucosal disease virus.
ADMINISTRATION AND DOSAGE
2 ml of the suspension obtained after the reconstitution of the vaccine in
the diluent amount corresponding to the number of doses in the vial are
inoculated by the intramuscular route, regardless of age.
Booster is 21 days later in previously unvaccinated reproduction cattle,
and 7 days later with the other age categories, in case vaccination I was
by aerosols or nasal instillations. Vaccinations for immunity maintenance
are given every year at 2 ml each by the intramuscular route.
CONTRAINDICATIONS
Diseased animals, with severe clinical prognosis.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 2, 5, 10 or 20 vaccinal doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

COLISER B
HYPERIMMUNE ANTI-ESCHERICHIA COLI SERUM FOR CALVES

COMPOSITION
Specific Escherichia coli K99 antibodies.
INDICATIONS
Prophylaxis and therapy of Escherichia coli infections in calves.
ADMINISTRATION AND DOSAGE
Preventively
Calves immediately post calving: 20-40 ml, subcutaneously.
Healthy calves in disease outbreaks: 30-50 ml, subcutaneously.
Curatively
Diseased calves before toxic forms occurrence: 40-100 ml,
subcutaneously.
CONTRAINDICATIONS
Simultaneous serovaccination, and vaccination within the first 21 days
post serum administration.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 50, 100 or 250

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

COLISER P
HYPERIMMUNE ANTI-ESCHERICHIA COLI SERUM FOR PIGLETS

COMPOSITION
Specific Escherichia coli antibodies.
INDICATIONS
Prevention and therapy of colibacillosis in new-born piglets.
ADMINISTRATION AND DOSAGE
Preventively:
2 ml/kg of live weight within the first hours post
farrowing with repetition after 12-14 hours, by the oral route.
Curatively: 3 ml/kg of body weight, to be repeated 24-48 hours later
depending on the clinical symptoms severity, by the oral route.
CONTRAINDICATIONS
New-born piglets or those before weaning.
POSTVACCINAL REACTIONS
When the serum is heterologous (prepared in cattle) sometimes
anaphylactic reactions may be noticed immediately after inoculation,
particularly if used curatively and repeatedly.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 50, 100 or 250 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

COLIVAC P
INACTIVATED VACCINE AGAINST PIGLET COLIBACILLOSIS

COMPOSITION
Six formalin- and heat-inactivated, and aluminium hydroxide- or saponinadjuvanted Escherichia coli strains having antigens involved in the
disease pathogenesis.
INDICATIONS
Specific prophylaxis of colibacillosis of suckling piglets by immunising the
dams during the pregnancy.
ADMINISTRATION AND DOSAGE
Inoculation I:
2 ml, by the subcutaneous route, after 75 days of
gestation.
Inoculation II:
3 ml, by the subcutaneous route, after 95 and not
later than 100 days of gestation.
CONTRAINDICATIONS
Herds where infectious and contagious diseases are present, animals
having over 100 days of gestation.
POSTVACCINAL REACTIONS
Local ones: Variable-in-size oedemata may occur that disappear after 34 days.
Systemic ones: Sometimes slight fever that may pass unnoticed and is
sometimes accompanied by a feed-intake decrease for 1-2 days.
Under the conditions of current practice, the inoculation may induce,
irrespective of the manufacturer, occasional anaphylactic reactions to
some animals. The animals should be observed for 1-2 hours post
vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 50 or 125 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

DISER
HYPERIMMUNE SERUM AGAINST
LAMB ANAEROBIC DYSENTERY

COMPOSITION
antitoxins against Clostridium perfringens.
INDICATIONS
Prevention and control of the anaerobic dysentery of lambs.
ADMINISTRATION AND DOSAGE
Preventively: 5 ml, by the subcutaneous route.
Curatively: 10-15 ml, by the subcutaneous route.
CONTRAINDICATIONS
The treatment is no longer indicated if sanguinolent diarrhoea occurs
during the disease course.
POSTVACCINAL REACTIONS
No local reactions are noticed in the lambs preventively administered the
serum; when the curative doses are repeated, tremors and salivation may
be recorded. In such cases, tranquillisers are recommended.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 20 or 50 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ECVIPARVAC
INACTIVATED VACCINE AGAINST HORSE PARAINFLUENZA

COMPOSITION
Formalin-inactivated and aluminium hydroxide-adsorbed type 3
parainfluenza virus.
INDICATIONS
Preventive or emergency purposes in horses.
ADMINISTRATION AND DOSAGE
Vaccination is at a subcutaneous dose of 2 ml, with booster 20 days later,
only in animals over 30 days of age or in mares during gestation months
VIII and IX. Maintenance vaccination is every 6 months at a single 2 ml
dose.
CONTRAINDICATIONS
Foals below 30 days of age, diseased or febrile animals, those in herds
where other infectious and contagious diseases are present.
POSTVACCINAL REACTIONS
A flat oedema occurs at the inoculation site 1-2 days post vaccination; it
resorbs leaving behind a hazel-like nodule.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 10 or 25 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

EMFIVAC
INACTIVATED VACCINE AGAINST BLACK LEG

COMPOSITION
Anaculture and anatoxin of formalin-inactivated and aluminium hydroxideadsorbed Clostridium chauvoei.
INDICATIONS
Immunisation of cattle and sheep against black leg.
As a rule, preventive vaccinations are applied in the cattle herds and
areas where the disease occurs enzootically. Emergency vaccinations
may be given too (post disease episodes occurrence). Only clinically
healthy animals should be vaccinated. Also, the animals moved from
disease-free areas to those where the disease was or is enzootic should
be vaccinated.
ADMINISTRATION AND DOSAGE
Cattle: Beginning with the age of over 4 months, during April-May, with a
booster 5-6 months later (October).
Sheep: From the age of 3 months up.
Inoculation is subcutaneous, on the neck side or behind the shoulder
blade.
The vaccinal dose is 3 ml (cattle) and 2 ml (sheep) given twice at 28 days
of interval.
CONTRAINDICATIONS
Associated vaccinations. Animals with other infectious diseases.
Cows and ewes during the last 2 months of gestation or the first 2-3
weeks post parturition. Recently castrated males or those shortly after
horns amputation, or sheep immediately after shearing.
Following tiresome transportations, the animals should be vaccinated but
48 hours post arrival at the farms.
POSTVACCINAL REACTIONS
A 3-4 cm nodule may develop at the inoculation site, that resorbs in time.
Under the conditions of current practice, the inoculation of some vaccines
may induce, irrespective of the manufacturer, occasional anaphylactic
reactions to some animals. The animals should be observed for 1-2 hours
post vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 33 or 80 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ERINVAC
INACTIVATED VACCINE AGAINST EQUINE RHINOPNEUMONIA

COMPOSITION
Saponin-inactivated and aluminium hydroxide-adsorbed equine herpes
virus, strains M508 and M75 grown on cell cultures.
INDICATIONS
Prevention of the rhinopneumonia virus-induced abortion in mares,
pulmonary conditions in foals and young horses.
The preventive vaccination of pregnant mares is recommended during
gestational months V-VII. The emergency vaccination may be applied to
pregnant mares irrespective of the gestational period.
ADMINISTRATION AND DOSAGE
A strictly subcutaneous dose of 2 ml is given in the third middle of the
week with booster 20 days later. Revaccination is every 6 months at a
single 2 ml dose.
The vaccine bottle should be vigorously shaken before inoculation.
CONTRAINDICATIONS
Foals below 30 days of age, diseased or febrile animals, those in herds
where other infectious and contagious diseases are present.
POSTVACCINAL REACTIONS
A small flat oedema occurs at the inoculation site 1-2 days post
vaccination; it subsides 5-7 days later leaving behind a hazel-like nodule.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 5, 25 or 50 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

IBR - IPV - VAC


MODIFIED LIVE VACCINE AGAINST INFECTIOUS
BOVINE RHINOTRACHEITIS -INFECTIOUS
PUSTULAR VULVOVAGINITIS OF CATTLE
(freeze-dried)

COMPOSITION
Bovine herpes virus type 1 (BHV-1) grown on bovine diploid cell cultures.
INDICATIONS
Prevention of the various forms of the bovine herpes virus infection.
ADMINISTRATION AND DOSAGE
2 ml of the suspension obtained by the reconstitution of the freeze-dried
vaccine in the diluent amount corresponding to the number of doses in the
vial are inoculated by the intramuscular route, regardless of age.
Booster is 21 days later in previously unvaccinated breeding cattle, and 7
days later with the other age categories, in case vaccination I was by
aerosols or nasal administration. Vaccinations for immunity maintenance
are given every year at 2 ml by the intramuscular route.
CONTRAINDICATIONS
Diseased animals.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 2, 5, 10 or 50 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LEPTOVAC
VACCINE AGAINST LEPTOSPIROSIS
OF CATTLE, SHEEP, HORSES AND PIGS

COMPOSITION
Several inactivated and aluminium hydroxide-adsorbed Leptospira spp.
serotypes with a minimum concentration of 106 germs/ml.
INDICATIONS
Cattle, sheep, horses, pigs: Preventive and emergency immunisation.
ADMINISTRATION AND DOSAGE
Pigs: 1 ml administered by the subcutaneous route for the mono- or
bivalent vaccine, and 2 ml for the tri-, tetra-, and pentavalent vaccine.
Boars: Quarterly.
Young and adult boars newly introduced into the farm: Twice at a 21 day
interval, and then each trimester.
Breeding gilts: Twice at 21 days of interval before being brought to the
ready-to-farrow box.
Pregnant sows: Vaccinations I and II are at 55 and 70 days of gestation
respectively.
Cattle, sheep, horses: 2 ml administered by the subcutaneous route.
Preventive vaccination
Pregnant animals: Twice at a 21 days interval during the first half of
gestation.
Young animals: Twice at 21 days of interval. The maintenance
vaccinations are every 6 months at a single dose.
Emergency vaccination
The diseased or disease suspect animals in the active or stationary
outbreaks of leptospirosis should be isolated and treated; the same
vaccination scheme is then applied.
CONTRAINDICATIONS
Animals during the last gestational half.
Animals under stress.
Animals affected by infectious and contagious diseases.
POSTVACCINAL REACTIONS
Nodules may sometimes develop at the inoculation site; they resorb in
time.
Under the conditions of current practice, the inoculation of certain
vaccines may induce, irrespective of the manufacturer, occasional
anaphylactic reactions to some animals. The animals should be observed
for 1-2 hours post vaccination; if necessary, an antihistaminic will be
applied.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 10, 25, 50 or 125 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

MAMIVAC
INACTIVATED VACCINE AGAINST
SHEEP GANGRENOUS MASTITIS

COMPOSITION
Broth culture of aluminium hydroxide-adsorbed and formalin- and heatinactivated Staphylococcus aureus.
INDICATIONS
Immunoprophylaxis of sheep gangrenous mastitis.
Sheep are emergency post lambing vaccinated. In some cases flocks
where the disease occurs annually and in a higher percentage of sheep,
etc. vaccinations may also be administered during the gestational period
with measures as to prevent postvaccinal accidents.
ADMINISTRATION AND DOSAGE
It is subcutaneously administered at 3 ml. Revaccination is 21 days later
at the same dose and by the same route.
CONTRAINDICATIONS
Animals during the last gestation month, those under stress and those
affected by infectious and contagious diseases, the parasitised ones.
POSTVACCINAL REACTIONS
Slight systemic reactions may sometimes occur that are completely
remitted within the first 24 hours.
Under the current practice conditions, the inoculation of certain vaccines
may induce, irrespective of the manufacturer, anaphylactic reactions to
some animals. The animals should be observed for 1-2 hours post
vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 15, 30 or 80 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

MYCOVAC
Combined vaccine against sheep and goat

CONTAGIOUS AGALACTIA AND PARATUBERCULOSIS

COMPOSITION
Inactivated Mycobacterium paratuberculosis and Mycoplasma agalactiae
in an oily emulsion.
INDICATIONS
Prevention of contagious agalactia and paratuberculosis in sheep and
goats.
ADMINISTRATION AND DOSAGE
1 ml by the intramuscular route.
CONTRAINDICATIONS
Diseased animals, those during the last 2 gestational months.
POSTAVACCINAL REACTIONS
A nodule occurs at the inoculation site.
The inoculation in the thigh muscles may be followed by slight lameness
that is remitted a few days later.
Under the current practice conditions, the inoculation of certain vaccines
may induce, irrespective of the manufacturer, anaphylactic reactions to
some animals. The animals should be observed for 1-2 hours post
vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 20, 50 or 100 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OVIPARVAC
MODIFIED LIVE VACCINE AGAINST SHEEP PARAINFLUENZA
(freeze-dried)

COMPOSITION
Parainfluenza type 3 virus, strain 0-107/77 grown on bovine kidney cell
cultures.
INDICATIONS
Prevention of the parainfluenza type 3 virus induced abortion of sheep,
and pulmonary conditions of young sheep starting with day 1 of life.
ADMINISTRATION AND DOSAGE
Adult sheep: 2 ml by the intramuscular route.
Young sheep, lambs: 1 ml.
Lambs: Starting with day 1 of life and 20 days later by the intramuscular
route each time. To avoid pneumonias occurrence during the weaning
stress, lambs are recommended to be revaccinated 20-30 days before
weaning. In the flocks with lamb losses caused by the type 3
parainfluenza-induced conditions, the lambs should be administered
serum against type 3 parainfluenza, and vaccinated 14-20 days later.
These lambs will be revaccinated 20-30 days before weaning.
The other sheep (adults, breeding rams) and the young will be
vaccinated every 6 months.
CONTRAINDICATIONS
Diseased animals with a severe clinical prognosis.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 5, 10 or 100 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PARAMYCOVAC
INACTIVATED VACCINE AGAINST RUMINANT PARATUBERCULOSIS

COMPOSITION
Heat-inactivated Mycobacterium johnei in an oily emulsion.
INDICATIONS
Cattle, sheep, goats: Emergency vaccination.
ADMINISTRATION AND DOSAGE
Cattle: 2 ml are subcutaneously inoculated into the dewlap.
Sheep, goats (starting with 7 days of age): 1 ml is intramuscularly into
the buttocks.
Immunity is prolonged by revaccination:
Adult cattle: 10 months post vaccination I.
Young cattle: 6-8 months post vaccination I.
The maintenance vaccination is every 12 months by the same scheme.
Adult sheep: 10 months post vaccination I.
Young sheep: 4-6 months post vaccination I.
The maintenance vaccination is at a 10-12 month interval.
CONTRAINDICATIONS
Animals with clinical forms of paratuberculosis, sheep and goats in the last
2 months of gestation, and animals on bovine tuberculosis-affected farms.
POSTVACCINAL REACTIONS
An oedema occurs at the inoculation site that develops, in cca 30 days,
into a nodule. Lameness and changed overall condition are recorded in
sheep and goats (in lambs in particular), that are remitted within a few
days.
STORAGE
At 4-8oC, protected from light.
PACKAGING
Bottle of 25 or 50 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PESTIVAC
MODIFIED LIVE VACCINE AGAINST
CLASSICAL SWINE FEVER
(freeze-dried)

COMPOSITION
Classical swine fever virus strain IP77 (Pasteur Institute 77) grown on the
established PK15 cell line.
INDICATIONS
Preventively, as follows:
Farms, units
Piglets aged 55-60 days, with booster at 120 days of age.
Boars, reproduction sows: Twice a year, during trimesters I and III.
Households
All pigs aged over 60 days: Mass vaccinations twice a year, during
trimesters I and III.
All new incoming animals: Monthly vaccinations.
ADMINISTRATION AND DOSAGE
The vaccinal intramuscular dose is 1 ml of the suspension obtained by
diluting the vial content in a diluent amount equal to the label-stated doses
number.
CONTRAINDICATIONS
Animals in the herds where highly diffusible infectious and contagious
diseases are present.
POSTVACCINAL REACTIONS
No local or systemic reactions occur regardless of the administration age.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 10, 20, 50, 100 or 200 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PESTRUVAC
MODIFIED LIVE VACCINE AGAINST CLASSICAL SWINE
FEVER AND ERYSIPELAS (freeze-dried)

COMPOSITION
Classical swine fever virus and a culture of Erysipelothrix rhusiopathiae,
strain VR 2.
INDICATIONS
Immunoprophylaxy of classical swine fever and erysipelas.
ADMINISTRATION AND DOSAGE
The vaccinal dose is 1 ml of the suspension obtained by diluting the
content of a vial in an equal amount of diluent corresponding to the labelstated number of doses.
The vaccine is administered by the intramuscular route.
Large-scale farms
Piglets are vaccinated at 60 and 120 days of age.
Fatteners over 270 days of age are revaccinated.
Breeders are vaccinated twice a year, during trimesters I and III.
Households
All pigs older than 60 days: Mass vaccinations twice a year, during
trimesters I and III.
All new incoming animals: Monthly vaccinations.
CONTRAINDICATIONS
Animals in the herds where highly diffusible infectious and contagious
diseases are present.
Antibiotics and/or chemotherapeutics administration is forbidden 7 days
before and post vaccination. When antibiotics treatments are necessary to
be applied in the herds, the vaccination is to be repeated 5 days after the
treatment was discontinued.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 5, 10, 20, 50, 100 or 200 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PNEUMOSUIVAC
INACTIVATED TRIVALENT VACCINE AGAINST
PIG INFECTIOUS PLEUROPNEUMONIA

COMPOSITION
Formalin- and heat-inactivated, and aluminium hydroxide-adsorbed
Actynobacillus pleuropneumoniae, Pasteurella multocida and Bordetella
bronchiseptica germs.
INDICATIONS
Pig herds with losses induced by pig infectious pleuropneumonia alone or
associated with P. multocida and B. bronchiseptica infections.
ADMINISTRATION AND DOSAGE
Intramuscularly at an age- and physiological status-dependent dose as
follows:
Disease begins in suckling pigs: Vaccination I, 2 ml at 7 days of age;
vaccination II, 3 ml at 21 days of age; vaccination III, 3 ml at 55 or 65
days of age (vaccination against swine fever may be concomitant but at
separate sites).
Disease begins in young pigs: Vaccination I, 3 ml at 15-20 days of age;
vaccination II, 3 ml at 30-35 days of age; vaccination III, 3 ml by the
intramuscular route at 55 or 65 days of age.
Vaccinations in sucklers are paralleled by mass vaccinations in boars,
sows and gilts with a 5 ml booster 21 days later.
1 Two months after the mass vaccination, the pregnant sows and gilts are
vaccinated at each pregnancy simultaneously with the vaccination against
colibacillosis and anaerobiosis at separate sites, however, and at a single 5
ml dose.
2 Boars are vaccinated every 6 months at 5 ml.
Post reduction in disease episodes incidence and when no
pleuropneumonia lesions are found on necropsy, vaccinations are as
follows:
Young animals: Vaccination I, 3 ml at 50 days of age; vaccination II, 3 ml
at 70 days of age.
Stock animals are further vaccinated as under 1 and 2.
CONTRAINDICATIONS
Sows during the last 14 days of gestation, clinically diseased animals that
are to be vaccinated after clinical signs remission only.
POSTVACCINAL REACTIONS
Some animals may exhibit a slight subfebrile condition that remits in 1-2
days.
Under the conditions of current practice, the inoculation of some vaccines
may induce, irrespective of the manufacturer, occasional anaphylactic
reactions to some animals. The animals should be observed for 1-2 hours
post vaccination; if necessary, an antihistaminic will be administered.
STORAGE o
At 2-8 C, protected from light.
PACKAGING
Bottle of 25, 50 or 125 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

POLIMASTIVAC
INACTIVATED VACCINE AGAINST COW MASTITIS

COMPOSITION
Staphylococcus aureus, Staphylococcus agalactiae and Streptococcus
dysgalactiae anacultures and anatoxins.
INDICATIONS
Prevention and control of clinical and subclinical mastites of pregnant or
dry cows.
ADMINISTRATION AND DOSAGE
A subcutaneous 5 ml dose is administered twice, 30 days apart, in the
region of the retromammary lymph nodes.
Six months post vaccination II and every 6 months thereafter,
revaccination is applied at a single 5 ml dose each.
CONTRAINDICATIONS
Cows should not be vaccinated minimum 30 days before calving, as to
avoid possible abortions.
POSTVACCINAL REACTIONS
A small oedema may occur at the inoculation site 24 hours later; it
disappears within 48-72 hours.
Under the current practice conditions, the inoculation of certain vaccines
may, irrespective of the manufacturer, cause anaphylactic reactions to
some animals. The animals should be observed for 1-2 hours post
vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 20 or 50 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

RABIVAC E
MODIFIED LIVE VACCINE AGAINST RABIES
(freeze-dried)

COMPOSITION
Fixed rabies virus, strain Era grown on cell cultures.
INDICATIONS
Preventively for the immunisation of ruminants, horses and pigs.
ADMINISTRATION AND DOSAGE
Intramuscularly at 1 ml irrespective of the animals species. In the disease
outbreak the doses are as follows:
Sheep, pigs: 1 ml.
Horses, cattle: 3 ml.
Generally, the vaccination is recommended starting with 6 months of age
with annual repetition.
CONTRAINDICATIONS
Diseased animals.
PRECAUTIONS
The vaccine is to be used, after dilution, within maximum 1 hour and 2
hours in summer and winter respectively.
These intervals once elapsed, the diluted vaccine must be discarded.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 1, 5 or 10 doses, with diluent

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

RINOVAC B
INACTIVATED VACCINE AGAINST
INFECTIOUS BOVINE RHINOTRACHEITIS

COMPOSITION
1 ml contains:
Infectious bovine rhinotracheitis virus
106.5 CPD50
Saponine
3 mg
Aluminium hydroxide
3 mg
IMMUNOLOGICAL ACTION
Immunity sets in 14-21 days post the booster.
INDICATIONS
Prevention and control of the infectious bovine rhinotracheitis viral
infection in the cows and bulls on reproduction farms.
ADMINISTRATION AND DOSAGE
Subcutaneously (in the neck region), at 5 ml with a booster 15-20 days
later at the same dose by the same route. The maintenance vaccination is
at a single dose every 6 months.
POSTVACCINAL REACTIONS
No particular systemic reactions are induced. A 2-3 cm nodule is
recorded at the inoculation site, that resorbs within 2-3 weeks.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 50 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ROMPERVAC ABCD
INACTIVATED VACCINE AGAINST RUMINANT ANAEROBIOSES

COMPOSITION
Formalin-inactivated and aluminium hydroxide-adsorbed anacultures and
anatoxins of Clostridium perfringens, types A, B, C and D.
INDICATIONS
Adult and young sheep aged over 3 months: Immunisation against
anaerobic enterotoxaemia.
Lambs: Immunisation against anaerobic dysentery.
Calves: Immunisation against anaerobic enteritis.
ADMINISTRATION AND DOSAGE
Adult sheep: Vaccination I, 2 ml by the subcutaneous route; vaccination
II, 3 ml by the subcutaneous route 25-30 days later. The maintenance
vaccination is every 6 months.
Young sheep of minimum 10 kg: Vaccination I, 4 ml by the subcutaneous
route; vaccination II, 4 ml at 2 separate sites 25-30 days later. The
maintenance vaccination is every 6 months.
Calves older than 2 months: Vaccination I, 5 ml by the subcutaneous
route; vaccination II, 5 ml by the subcutaneous route 25-30 days later.
The maintenance vaccination is every 6 months.
CONTRAINDICATIONS
Ewes during the last gestation month, hypothreptic lambs.
POSTVACCINAL REACTIONS
A 2-3 cm in diameter nodule develops at the inoculation site, that resorbs in
time.
Depending on the site of inoculation lameness of variable intensity may
occur post vaccination; it subsides in a few days.
Under the current practice conditions, the inoculation of certain vaccines
may induce, irrespective of the manufacturer, anaphylactic reactions to
some animals. The animals should be observed for 1-2 hours post
vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 50 or 125 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ROMPERVAC AC
INACTIVATED VACCINE AGAINST PIGLET ANAEROBIOSIS

COMPOSITION
Formalin-inactivated and aluminium hydroxide-adsorbed anacultures and
anatoxins of Clostridium perfringens, types A and C.
INDICATIONS
Suckling piglets: Prevention of necrotic enteritis.
ADMINISTRATION AND DOSAGE
It is twice, 21 days apart, administered by the subcutaneous route to
pregnant sows:
Inoculation I: 4 ml at 75 days of gestation.
Inoculation II: 4 ml at 95 days of gestation.
POSTVACCINAL REACTIONS
A nodule 2-3 cm in diameter develops at the site of inoculation; it resorbs in
time.
Under the current practice conditions, the inoculation of certain vaccines
may induce, irrespective of the manufacturer, anaphylactic reactions to
some animals. The animals should be observed for 1-2 hours post
vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 25 or 60 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

RUVAC
MODIFIED LIVE VACCINE AGAINST ERYSIPELAS
(freeze-dried)

COMPOSITION
Erysipelothrix rhusiopathiae, strain VR 2.
INDICATIONS
Preventively, in the specific prophylaxy of pig erysipelas.
Farms
90 day old pigs, with repetition at 120 days of age.
Breeding boars, sows: Twice a year (trimesters I and III).
Private households
All pigs aged 90 days: Mass vaccinations twice a year (trimesters I and
III).
All new incoming animals: Monthly vaccinations.
ADMINISTRATION AND DOSAGE
The subcutaneous vaccinal dose of 1 ml is the vaccine suspension
obtained by dissolving the contents of a vial in a diluent amount equal to
the number of the label-stated doses.
CONTRAINDICATIONS
Vaccination should not be concomitant with anti-erysipelas serum
administration.
Animals having received antibiotics 7 days before vaccination.
Antibiotics should not be given at least 7 days post vaccination.
POSTVACCINAL REACTIONS
Sometimes febrile conditions and mild reactions may occur at the
inoculation site. Also, animals during the disease incubation period may
get diseased: the disease subsides readily to antibiotics. Sometimes
postvaccinal skin reactions may be noticed.
Under the conditions of current practice, the inoculation of some vaccines
may induce, irrespective of the manufacturer, occasional anaphylactic
reactions to some animals. The animals should be observed for 1-2 hours
post vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 5, 10, 20, 50, 100 or 200 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SALMOVAC Sm 237
MODIFIED LIVE VACCINE AGAINST PIG SALMONELLOSIS
(freeze-dried)

COMPOSITION
Salmonella choleraesuis, strain Sm 237. The germs number is > 1 x 109
CFU/dose.
INDICATIONS
Emergency immunisations only of the healthy animals on farms where the
S. choleraesuis-induced disease is enzootic.
ADMINISTRATION AND DOSAGE
A subcutaneous dose of 1 ml, with booster 14-20 days later, is
administered beginning with 20 days of age.
CONTRAINDICATIONS
Piglets with acute and chronic pulmonary conditions or in bad condition.
No antibiotics should be administered 5 days before and post vaccination.
POSTVACCINAL REACTIONS
Oedemata may occur at the inoculation site, that may persist as nodules.
Post vaccination I, slight depression may be recorded, that disappears
within 24-48 hours.
Under the current practice conditions, the inoculation of certain vaccines
may induce, irrespective of the manufacturer, anaphylactic reactions to
some animals. The animals should be observed for 1-2 hours post
vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 10, 20, 25, 50 or 100 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SALMOVIN
INACTIVATED VACCINE AGAINST SALMONELLA ABORTION IN SHEEP

COMPOSITION
Formalin- and heat-inactivated Salmonella abortus ovis in liquid medium.
INDICATIONS
Prevention and control of Salmonella-induced abortions, stillborn foetuses
and lamb mortality. In flocks with Salmonella-induced abortions and lamb
mortality, emergency vaccinations and antibiotics treatments may be
simultaneously applied.
ADMINISTRATION AND DOSAGE
During the first 3 months of gestation at a subcutaneous 3 ml dose, with a
5 ml booster 21 days later.
The emergency vaccination is subcutaneous at 5 ml. In sheep flocks
where the Salmonella-induced abortions have been present for several
years, the vaccine should be applied 3 times to ewe lambs.
Vaccination I is at a subcutaneous 5 ml dose during the service, while
vaccinations II and III are at the same dose each 30 days later each.
CONTRAINDICATIONS
Sheep during the last 20 days of gestation. It should not be applied
simultaneously with the anthrax vaccine.
POSTVACCINAL REACTIONS
Tumefactions and oedemata may occur at the inoculation site, as well as
apathy and subfebrile condition; they disappear within a few days.
Under the conditions of current practice, the inoculation of some vaccines
may induce, irrespective of the manufacturer, occasional anaphylactic
reactions to some animals. The animals should be observed for 1-2 hours
post vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 20 or 50 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SEPTIVAC
INACTIVATED VACCINE AGAINST
BOVINE HAEMORRHAGIC SEPTICAEMIA

COMPOSITION
Formalin- and heat-inactivated and aluminium hydroxide-adsorbed
Pasteurella multocida.
INDICATIONS
Cattle and buffaloes of any age in the risk areas: Prevention of
haemorrhagic septicaemia.
Adult animals in the households and localities of the areas where
haemorrhagic septicaemia is enzootic and where pasteurellosis episodes
have been reported of late years: Preventive vaccination.
ADMINISTRATION AND DOSAGE
Subcutaneously, twice at 21 days of interval as follows:
Calves up to 6 months of age: Vaccinations I and II at 4 ml each.
Calves over 6 months of age: Vaccinations I and II at 8 ml each.
CONTRAINDICATIONS
Diseased or parasitised animals, those with chronic conditions or food
poisoning, those in bad condition.
Anthrax and black leg vaccinations are not to be associated with this one.
POSTVACCINAL REACTIONS
Usually, no systemic reactions are recorded after vaccination.
Dyspnoea, hypersalivation and diarrhoea may occur in young animals;
they remit after 24 hours. An oedematous or hard nodule of variable
diameter develops at the inoculation site, that resorbs in time.
Under the conditions of current practice, the inoculation of some vaccines
may induce, irrespective of the manufacturer, occasional anaphylactic
reactions to some animals. The animals should be observed for 1-2 hours
post vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 25 or 60 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SEROGAN
ANTI-CLOSTRIDIUM PERFRINGENS
TYPE A, B, C, D HYPERIMMUNE SERUM

COMPOSITION
1 ml contains 2.5, 50 and 2.5 IU of , and antitoxins respectively
against Clostridium perfringens, types A, B, C and D.
INDICATIONS
Prevention and control of animal anaerobioses.
ADMINISTRATION AND DOSAGE
The recommended doses are dependent on the body weight:
Preventively: 0.25 ml/kg of body weight, by the subcutaneous route.
Curatively: 0.5 ml/kg of body weight, by the subcutaneous route.
CONTRAINDICATIONS
Ruminants should not be vaccinated against anaerobiosis during the first
21 days post serum administration.
POSTVACCINAL REACTIONS
In case the serum prepared in horses is used in ruminants, anaphylactic
reactions of various intensities may be noticed especially when high or
repeated curative doses are administered. In such cases, preliminary
desensitisations are applied with 0.2-0.4 ml of serum by the intradermic
route, and treatments with antihistaminics and tranquillisers as to
attenuate the heterologous protein-induced anaphylactic phenomena.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 50, 100 or 250 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SEROGAN AC
ANTI-CLOSTRIDIUM PERFRINGENS TYPE A, C SERUM

COMPOSITION
1 ml contains 5 and 100 IU of and antitoxins respectively against Cl.
perfringens, types A and C.
INDICATIONS
Prevention and control of anaerobiosis in pigs.
ADMINISTRATION AND DOSAGE
Preventively, per os and/or subcutaneously:
Sucklers: 3-5 ml
Sows: 15-20 ml
Curatively, per os and/or subcutaneously:
Sucklers: 5-10 ml
Sows: 40-60 ml
When the symptoms are severe the curative dose may be repeated 12-24
hours later.
The curative treatment has to be associated with sulphonamides or
antibiotics, and with a medication for the body general support.
CONTRAINDICATIONS
Vaccination against anaerobiosis is not recommended within the first 14
days post serum administration.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 50, 100 or 250 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SERVIPAST
HYPERIMMUNE SERUM ANTI-PASTEURELLA, INFECTIOUS BOVINE RHINOTRACHEITIS AND
PARAINFLUENZA TYPE 3 VIRUSES

COMPOSITION
Antibodies to Pasteurella and to infectious bovine rhinotracheitis-infectious
pustular vulvovaginitis and parainfluenza type 3 viruses.
INDICATIONS
Cattle: Prevention and control of viral lung conditions induced by
parainfluenza and rhinotracheitis, and associated with lung or septicaemic
pasteurellosis.
ADMINISTRATION AND DOSAGE
Preventively: 0.3-0.4 ml/kg of body weight by the subcutaneous route to
clinically healthy cattle on rearing and fattening farms where respiratory
conditions were diagnosed, and prior to shipment to cattle intended for
long transportation.
Curatively: 0.5-0.6 ml/kg of body weight.
CONTRAINDICATIONS
The animals having received the serum should be vaccinated against
pasteurellosis or respiratory viroses but minimum 21 days post serum
administration.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 100 or 250 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SUIGET
INACTIVATED VACCINE AGAINST
PIG TRANSMISSIBLE GASTROENTERITIS

COMPOSITION
Inactivated
and
aluminium
hydroxide-adsorbed
transmissible
gastroenteritis virus grown on pig renal cells.
INDICATIONS
Preventive and emergency vaccinations of breeding boars, and of all sows
during gestational month III for piglets protection during the first days post
farrowing.
ADMINISTRATION AND DOSAGE
Inoculation I: 2 ml, by the intramuscular route, at 75 days of gestation.
Inoculation II: 2 ml, by the intramuscular route, at 95 days of gestation.
Boars are vaccinated with the same doses at 21 days of interval; the
maintenance vaccination is every 6 months at the same doses.
CONTRAINDICATIONS
Herds where other infectious and contagious diseases of high diffusibility
are present.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 50 or 125 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SUIGET
MODIFIED LIVE VACCINE AGAINST
PIG TRANSMISSIBLE GASTROENTERITIS

COMPOSITION
Transmissible gastroenteritis virus attenuated on pig primary kidney cells.
INDICATIONS
Preventive and emergency vaccinations of breeding boars, and of all sows
during gestational month III, for piglets protection during the first days post
farrowing.
ADMINISTRATION AND DOSAGE
Inoculation I : 2 ml, by the intramuscular route, at 75 days of gestation.
Inoculation II : 2 ml, by the intramuscular route, at 95 days of gestation.
Boars are vaccinated with the same doses at 21 days of interval; the
maintenance vaccination is every 6 months at the same doses.
CONTRAINDICATIONS
Herds where other infectious and contagious diseases of high diffusibility
are present.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 50 or 125 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SUIPASTVAC
VACCINE AGAINST PIG PASTEURELLOSIS

COMPOSITION
Formalin- and heat-inactivated and aluminium hydroxide -adsorbed
Pasteurella multocida.
INDICATIONS
Prevention of pig pasteurellosis.
ADMINISTRATION AND DOSAGE
Subcutaneously, twice at 21 days of interval, as follows:
Pigs up to 6 months of age: Vaccination I, 3 ml.
Vaccination II, 5 ml.
Pigs over 6 months of age: Vaccination I, 5 ml.
Vaccination II, 10 ml.
CONTRAINDICATIONS
Diseased animals, those with chronic or acute conditions or in bad
condition.
POSTVACCINAL REACTIONS
An oedematous or hard nodule may be noticed at the inoculation site, that
resorbs in time.
Under the conditions of current practice, the inoculation of some vaccines
may induce, irrespective of the manufacturer, occasional anaphylactic
reactions to some animals. The animals should be observed for 1-2 hours
post vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 33 or 80 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TESER
HYPERIMMUNE ANTI-TETANUS SERUM

COMPOSITION
Minimum 200 IAU/ml of tetanus anatoxin.
INDICATIONS
Prevention and control of tetanus in animals.
ADMINISTRATION AND DOSAGE
Subcutaneously as follows:
Preventively
Animals up to 50 kg: 500 IAU.
Animals over 50 kg: 1000-1200 IAU.
Large animals: 1500 IAU.
Curatively
50,000-100,000 IAU as a single intramuscular or subcutaneous dose.
Depending on the clinical disease course, the dose may be repeated 2-3
days later.
The specific serum treatment will be associated, throughout the disease
course, with antibiotics and sedatives administration.
The international antitoxic units (IAU) titre is stated on each bottle label.
To determine the serum amount (ml) to be either preventively or curatively
administered to an animal in the field, the necessary IAU dose is divided
to the serum titre expressed as IAU/ml. For example: 500 IAU:100
IAU/ml=5ml.
POSTVACCINAL REACTIONS
As it is prepared in horses, it may induce anaphylactic phenomena to the
other animal species, that may be prevented by preliminary
desensitisations or treatments with antihistaminics and tranquillisers.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 100 or 250 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TETRAVAC B
TETRAVALENT VIRAL VACCINE
(freeze-dried)

COMPOSITION
Bovine virus diarrhoea, infectious bovine rhinotracheitis, parainfluenza
type 3 and bovine respiratory syncytial viruses grown on cell cultures.
INDICATIONS
Prevention and control of viral respiratory conditions (parainfluenza,
infectious bovine rhinotracheitis, bovine viral diarrhoea and bovine
respiratory syndrome) of calves and young cattle starting with 2-3 weeks
of age on cattle rearing and fattening farms.
It is used alone or associated with BIPAST B, a bivalent vaccine against
Pasteurella-induced bronchopneumonia of cattle.
ADMINISTRATION AND DOSAGE
The vaccinal dose is 2 ml, irrespective of age, of the suspension resulted
from the vaccine suspended in the diluent amount corresponding to the
label-stated dose number.
The administration is intramuscular or nasal.
The booster is 14-21 days later at the same dose.
CONTRAINDICATIONS
Reproductive animals on farms providing breeding stock or seminal
material.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 5, 10, 20 or 25 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TRICOVAC
VACCINE AGAINST CATTLE TRICHOPHYTOSIS

COMPOSITION
Minimum 106/ml of spores and hyphae fragments of an attenuated
Trichophyton verrucosum strain in an antibiotics-added physiological
saline.
INDICATIONS
Prevention and control of enzootic trichophytosis on cattle farms. It does
not induce clinical disease to healthy animals, and quickens the recovery
of the diseased ones.
ADMINISTRATION AND DOSAGE
Preventively, starting with 1 month of age as follows:
1-4 month old calves: 5 ml.
4-8 month old calves: 8 ml.
Calves over 8 months, adults: 10 ml.
The vaccine suspension should be shaken, before inoculation, until
homogenised. The inoculation is intramuscular into the rump. Two weeks
post inoculation I the same dose is repeated into the rump.
For emergency purposes, 2 inoculations are applied 2 weeks apart by the
same technique as with the preventive vaccination, but at double doses.
On the farms where trichophytosis is enzootic the entire herd should be
vaccinated; the calves reaching 1 month of age are vaccinated as well.
The vaccine association with zinc- and selenium-based products
inoculation at separate sites has a favourable effect on the immunity
setting in.
CONTRAINDICATIONS
The vaccination against trichophytosis should not be associated with other
immunoprophylactic procedures, with immunosuppressive or systemic
antimycotic treatments.
POSTVACCINAL REACTIONS
A deep small nodule develops at the inoculation site, that resorbs in the
weeks to follow.
About 2 weeks post vaccination II, a 10-20 mm in diameter crust looking
very much like the trichophytosis focus frequently occurs at the site of
inoculation; it heals spontaneously after cca 3 weeks.
The animals with chronic entero-pulmonary conditions develop a lower
immunity in comparison with the clinically healthy ones and those in good
condition.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 10, 20 or 40 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TRIVIRAL B
MODIFIED LIVE VACCINE AGAINST PARAINFLUENZA TYPE 3,
INFECTIOUS BOVINE RHINOTRACHEITIS AND BOVINE
VIRAL DIARRHOEA OF CATTLE (freeze-dried)

COMPOSITION
The infectious bovine rhinotracheitis virus, strain Oxford, the parainfluenza
type 3 virus, strain Cs 291 and the bovine viral diarrhoea virus, strain IL396/2 grown on calf kidney cells.
INDICATIONS
Prevention and control of bovine respiratory affections and breeding
disorders (abortions, endometrites) of viral aetiology.
ADMINISTRATION AND DOSAGE
Prevention purposes
Calves (starting with 2-3 weeks of age): 2 ml by the intramuscular route,
with repetition 15-20 days later.
Calves (starting with the first days of life): 2 ml by the nasal route (1 ml
into each nostril), with repetition 15-20 days later at 2 ml by the
intramuscular route.
Pregnant cows (starting with gestational month 7): 2 ml by the
intramuscular route, administered twice 15-20 days apart.
Emergency purposes
2 ml (the concentration is double, using the same diluent amount, i.e. 50
doses in 50 ml of diluent) by the intramuscular route.
CONTRAINDICATIONS
Breeding animals on farms providing breeding stocks or seminal material.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 5, 10 or 25 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BIAVAC
MODIFIED LIVE VACCINE AGAINST INFECTIOUS BURSAL DISEASE
(freeze-dried)

COMPOSITION
Infectious bursal disease virus grown on cellular cultures.
INDICATIONS
Specific prophylaxis of the infectious bursal disease of the young layers
and broilers in healthy, disease sensitive flocks adequately managed in
point of feeding and hygiene irrespective of the breeding system. It may
be used in healthy chickens on farms where the disease is enzootic.
ADMINISTRATION AND DOSAGE
Vaccination should take into consideration the chicken category and the
maternal antibody curve course that decreases quicker or slower
depending on the level transmitted by the parents (the parents
immunisation depends on how they were vaccinated and on their age).
The vaccination schemes comprise one, two or more vaccinations
depending on the objective, epidemiological status, chicken breed and
rearing conditions. Orientatively, vaccination I may be at 8-14 days of age,
the subsequent vaccination(s) being established, if need be, depending on
the antibody level and/or epidemiological status.
Ocular instillations:1000 doses of vaccine are dissolved in 50 ml of
diluent; one drop is administered into each eye.
Drinking water: The diluent is mixed with the vaccine, and the resulting
suspension is diluted in the drinking water free of chlorine and iron ions,
heavy metals, pesticides, radionuclides. 1000 vaccine doses are used in
7-20 l of water depending on the chickens age that will be off water for
24 hours. Optionally, the water may be added with 0.2-0.5% defatted
milk for the vaccine protection.
CONTRAINDICATIONS
Flocks where the disease is acute, or other infectious, contagious or
parasitic diseases are present.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 100, 500, 1000, 2000 or 5000 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BRONVAC
MODIFIED LIVE VACCINE AGAINST AVIAN INFECTIOUS BRONCHITIS
(freeze-dried)

COMPOSITION
Attenuated Massachussetts virus, strain H120 from infected hen embryos.
INDICATIONS
Preventively in breeders and young replacement birds, and for emergency
purposes in broiler chickens.
ADMINISTRATION AND DOSAGE
Young breeders and replacement pullets are vaccinated when 40-42 days
old with repetition at 70-75 days of age. The emergency vaccination in
broiler chickens is given at 1-4 days and repeated at 23-24 days of age.
Aerosol administration: The vaccine is resuspended in disinfectants-free
drinking water at 0.2-2 ml/bird depending on the aerosol generator used.
Drinking water administration: The vaccine will be reconstituted in a
water amount ensuring 20 ml for chickens below 30 days of age and 30
ml for older ones.
CONTRAINDICATIONS
Clinically diseased birds or those with deficiencies and metabolic
disorders.
POSTVACCINAL REACTIONS
Slight reactions, manifested by inappetence and respiratory phenomena
may occur post vaccination that disappear within a few days.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 500 or 1000 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

COLUMBO - DIV
MODIFIED LIVE VACCINE AGAINST PIGEON POX
(freeze-dried)

COMPOSITION
Turkey pox virus, strain BP from infected hen embryos.
INDICATIONS
Preventive and emergency purposes. Vaccination may be applied in any
season, irrespective of age or breed.
ADMINISTRATION AND DOSAGE
The vaccine is reconstituted in the diluent supplied (20 doses/4 ml; 40
doses/8 ml).
Administration is on the feather follicles of one of the legs. To this aim,
cca. 20 feathers on the antero-external side of the shank are plucked out,
and the skin is then painted with a vaccine-soaked cotton pad.
CONTRAINDICATIONS
Flocks with deficiencies and metabolic disorders, acute or chronic
diseases, heavy parasitic infestations.
POSTVACCINAL REACTIONS
No general postvaccinal reactions are noticed. 5-7 days post vaccination
folliculitis (skin inflammation) occurs on the painted area, that lasts for 10-15
days.
The pigeons with no typical reactions upon the control made 7 days post
vaccination, will be revaccinated under similar conditions in the other
leg.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 20 or 40 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

COLUMBOVAC
VACCINE AGAINST PIGEON NEWCASTLE
DISEASE AND PARAMYXOVIROSIS

COMPOSITION
Newcastle disease virus, lentogenic strain La Sota, and the pigeon
paramyxovirosis virus, strain PMV-1 grown on hen embryos.
INDICATIONS
Immunoprophylaxis of Newcastle disease and paramyxovirosis of
pigeons.
ADMINISTRATION AND DOSAGE
Subcutaneously at 0.2 ml into the nape.
CONTRAINDICATIONS
It should not be used for emergency purposes in birds affected by
paramyxovirosis, Newcastle disease, other viral, bacterial or parasitic
diseases.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 50 or 100 de doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

DI - COL
MODIFIED LIVE VACCINE AGAINST FOWL POX
(freeze-dried)

COMPOSITION
Fowl pox virus, strain Col-OF from infected hen embryos.
INDICATIONS
Preventive vaccination of 60-75 day old young birds (hens, turkeys,
pheasants). With the flocks in areas under risk, the vaccination may be
applied at 45 days of age, followed by revaccination with DI-GAL after 30
days.
ADMINISTRATION AND DOSAGE
The vaccine is rehydrated in the diluent corresponding to the label-stated
number of doses (250 doses/2.5 ml, 500 doses/5 ml).
The vaccine is transdermally applied by the Stick method (the wing web
penetration at the humero-radio-cubital angle) with the vaccinating device
soaked into the reconstituted vaccine. The device should ensure the
transdermal inoculation of 0.01 ml of the vaccine suspension
corresponding to a vaccinal dose. It should be degreased, post each
vaccination, with clean diluent. A device is recommended for 1000
vaccinations. The turkey vaccination is by painting an area on the shank
anterior side, after a few feathers plucking out.
CONTRAINDICATIONS
Birds formerly diseased with fowl pox, those with deficiencies and
metabolic disorders or with other conditions should not be vaccinated for
12-14 days after DI-COL application.
POSTVACCINAL REACTIONS
Within the first 4-5 days post vaccination slight systemic reactions
adynamia, reduced appetite may occur in young flocks with vitamin and
trace elements deficiencies in particular.
The local reactions delimited or confluent, hard fowl pox nodules of
variable size depending on the birds sensitivity and age occur 7-10 days
later.
The local reactions may be absent:
In previously vaccinated or formerly diseased flocks.
In birds/flocks where the vaccination technique was faulty.
When the vaccine is inadequately carried or stored, or expired.
To check immunity establishment, minimum 15-20% birds (large flocks) or
all the birds (small flocks) should be checked for nodules. In case more
than 30% of the flock exhibits no nodules when checked for local
postvaccinal reactions, revaccination in the other wing is recommended.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 250 or 500 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

DI - GAL
MODIFIED LIVE VACCINE AGAINST FOWL POX
(freeze-dried)

COMPOSITION
Fowl pox virus, strain GAL-MP1 from infected hen embryos.
INDICATIONS
Immunisation of hens, turkeys and pheasants. In hens, it is used as a booster at a 30-day
interval post the DI-COL vaccine administration.
Given some peculiarities, it is administered preventively:
On farms with fowl pox episodes in previous years, or when unvaccinated birds are
introduced into a vaccinated flock.
Four weeks at least before the point of lay.
Vaccination should be given to the whole flock within the shortest time possible. Should
this be impossible, the vaccinated groups should be separated from the unvaccinated
ones.
The virus inoculation into other sites should be avoided.
Vaccination should not be given below 3 months of age. In emergency cases, the
minimal age (contaminated flocks) may be lowered up to 2 months.
In private households, vaccination will be applied during May-September.
In disease outbreaks, the clinically healthy birds are to be vaccinated, while the
diseased ones will be slaughtered.
ADMINISTRATION AND DOSAGE
The vaccine is reconstituted in the diluent corresponding to the label-stated number of
doses: 500 doses/5 ml, 1000 doses/10 ml, 2000 doses/20 ml, etc.
The transdermic Stick method (wing web penetration at the humero-radio-cubital angle)
with the vaccinating device soaked into the reconstituted vaccine is used in hens and
pheasants. Turkeys are vaccinated by painting the entire thigh or shank area, as the
Stick method would lead to extended wattle lesions.
CONTRAINDICATIONS
Birds with respiratory conditions or metabolic disorders, the parasitised or deficient ones.
Cold seasons or rainy weather.
POSTVACCINAL REACTIONS
Within the first 4-5 days post vaccination slight systemic reactions adynamia, reduced
appetite may occur in young flocks with vitamin and trace elements deficiencies in
particular.
The local reactions occur 7-10 days later; they consist in defined or confluent pox
nodules that are hard and of variable size depending on the birds age and sensitivity.
The local reactions may be absent:
In previously vaccinated or formerly diseased flocks.
In birds/flocks where the vaccination technique was faulty.
When the vaccine is inadequately carried or stored, or expired.
To check immunity establishment, minimum 15-20% birds (large flocks) or all the birds
(small flocks) should be checked for nodules. In case more than 30% of the flock exhibits
no nodules when checked for local postvaccinal reactions, revaccination in the other wing
is recommended.
STORAGE
At 2-8oC, protected from light and freezing.
PACKAGING
Vial of 1000, 2000 or 3000 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GUMBOINVAC
INACTIVATED VACCINE AGAINST INFECTIOUS BURSAL DISEASE

COMPOSITION
Minimum 105.5 CPID50/ml of formalin-inactivated infectious bursal disease
virus in an oily emulsion.
INDICATIONS
Specific prophylaxis of infectious bursal disease of 18-20 week old poultry
previously vaccinated with a live vaccine. Also, for the revaccination of the
hens with a low serum antibody level.
ADMINISTRATION AND DOSAGE
It should be kept at room temperature for 2-3 hours before use for
fluidisation, and shaken throughout the vaccination period.
It is administered intramuscularly (the thigh muscles) or subcutaneously
into the nape ( the suboccipital region) at 0.5 ml.
CONTRAINDICATIONS
Flocks where acute infectious diseases are present.
POSTVACCINAL REACTIONS
No systemic reactions occur. A local diffuse or nodular reaction that
resorbs in 7-10 days may occur.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 200, 400 or 800 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LARINGOVAC
MODIFIED LIVE VACCINE AGAINST
AVIAN INFECTIOUS LARYNGOTRACHEITIS
(freeze-dried)

COMPOSITION
Avian infectious laryngotracheitis virus, strain LT-79-2 from infected hen
embryos.
INDICATIONS
Specific prophylaxis of avian infectious laryngotracheitis of healthy birds
on farms and households where the disease occurs systematically. The
vaccination age is 4 weeks. Young breeders and replacement birds are
revaccinated at 16-20 weeks of age.
ADMINISTRATION AND DOSAGE
Eye drop: A drop of the diluent-reconstituted vaccine (1000 doses/100 ml,
2000 doses/200 ml) into each conjunctival sac. All the hens in a house
should be vaccinated on the same day.
CONTRAINDICATIONS
Flocks where other respiratory diseases are present, hens during laying.
POSTVACCINAL REACTIONS
Conjunctival and respiratory reactions may occur 3-4 days post
vaccination, caused by an inadequate microclimate. They disappear within
3-4 days.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 1000 or 2000 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ND - GUMBOINVAC
OILY INACTIVATED VACCINE AGAINST NEWCASTLE DISEASE
AND INFECTIOUS BURSAL DISEASE

COMPOSITION
Oily emulsion-incorporated lentogenic Newcastle disease virus strain
grown on hen embryos and the infectious bursal disease virus strain
grown on formalin-inactivated cell cultures.
INDICATIONS
Specific prophylaxis of Newcastle disease and infectious bursal disease of
the healthy young in reproductive and selection flocks previously
vaccinated with live vaccines. It will be administered before the transfer to
the formerly diseased adults (115-126 days old) house.
It may also be administered after inactivated monovalent vaccines, e.g.
NEDEVAC and GUMBOINVAC. In such cases, the booster with ND-GUMBOINVAC
after minimum 4 weeks ensures the respective flocks a high, constant and
uniform immunity.
ADMINISTRATION AND DOSAGE
It should be kept at 18-20oC for 2-3 hours before use for fluidisation, and
agitated for homogenisation both before and during vaccination whenever
needed.
The administration is intramuscular (the thigh or breast muscles) or
subcutaneous (the lower third of the posterior neck region) at 0.5 ml.
CONTRAINDICATIONS
Flocks where other diseases are present.
POSTVACCINAL REACTIONS
No systemic reactions occur. Sometimes a local reaction may occur that
remits shortly.
STORAGE
At 2-8o C, protected from light.
PACKAGING
Bottle of 160 or 400 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ND - SINCO - GUMBOINVAC
OILY INACTIVATED VACCINE AGAINST NEWCASTLE DISEASE, EGG DROP SYNDROME76 AND
INFECTIOUS BURSAL DISEASE

COMPOSITION
Oily emulsion incorporated lentogenic Newcastle disease virus strain
grown on hen embryos, the egg syndrome virus, strain 127 grown on duck
embryos and the infectious bursal disease virus strain grown on cell
cultures. The three viral components are formalin-inactivated.
INDICATIONS
Specific prophylaxis of Newcastle disease, egg drop syndrome and
infectious bursal disease of the healthy young in reproductive and
selection flocks previously vaccinated against Newcastle disease and
infectious bursal disease with live vaccines. It will be administered before
the transfer to the formerly diseased adults (115-126 days old) house, and
to the flocks with egg drop syndrome-induced decreases in the egg yield.
It may also be administered after inactivated monovalent vaccines, e.g.
NEDEVAC and GUMBOINVAC. In such cases, the booster with ND-SINCOGUMBOINVAC after minimum 4-6 weeks ensures the respective flocks and their
progeny a high, constant and uniform immunity.
ADMINISTRATION AND DOSAGE
It should be kept at 18-20oC for 2-3 hours before use for fluidisation, and
agitated for homogenisation both before and during vaccination whenever
needed.
The administration is intramuscular (the thigh or breast muscles) or
subcutaneous (the lower third of the posterior neck region) at 0.5 ml.
CONTRAINDICATIONS
Flocks where other diseases are present.
POSTVACCINAL REACTIONS
No systemic reactions occur. Sometimes a local reaction may occur that
remits shortly.
STORAGE
At 2-8o C, protected from light.
PACKAGING
Bottle of 160 or 400 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ND - SINCOVAC
OILY INACTIVATED VACCINE AGAINST
NEWCASTLE DISEASE AND EGG DROP SYNDROME76

COMPOSITION
Oily emulsion incorporated egg drop syndrome virus, strain 127 and a
Newcastle disease virus strain (La Sota or LS79).
INDICATIONS
Specific prophylaxis of Newcastle disease and egg drop syndrome of
healthy young poultry free from egg drop syndrome antibodies and
previously vaccinated against Newcastle disease. It is administered before
the transfer to the adults house with a history of the egg drop syndrome, at
115-126 days of age.
ADMINISTRATION AND DOSAGE
It should be kept at 18-20oC for 2-3 hours before use for fluidisation, and
agitated for homogenisation both before and during vaccination whenever
needed.
The administration is intramuscular (the thigh or breast muscles) or
subcutaneous (the neck) at 0.5 ml.
CONTRAINDICATIONS
Diseased poultry.
POSTVACCINAL REACTIONS
No apparent systemic reactions occur. A short-term local reaction occurs.
STORAGE
At 2-8o C, protected from light.
PACKAGING
Bottle of 200 or 400 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

NEDEVAC
OILY INACTIVATED VACCINE AGAINST NEWCASTLE DISEASE

COMPOSITION
Lentogenic formalin-inactivated and oily emulsion-incorporated Newcastle
disease virus, strain La Sota.
INDICATIONS
Specific prophylaxy of Newcastle disease in sensitive birds (hens,
turkeys), particularly in those intended for reproduction and selection.
ADMINISTRATION AND DOSAGE
It is administered by the subcutaneous (the cervical region) or
intramuscular route (thigh, breast) at 0.5 ml/bird.
Hens: Vaccinations I and II are at 17-18 and at 42-44 weeks of age
respectively (the preceding ones are with NEWVAC).
The subsequent, every 4 months vaccinations are at 0.5 ml of NEDEVAC.
Turkeys: Vaccination I is at 4 weeks of age, and the subsequent ones at
9, 10, 24 and 45-50 weeks.
CONTRAINDICATIONS
Emergency vaccination, during moulting, or earlier than 8 weeks before
slaughter. The birds clinically diseased with infectious and parasitic
diseases or with deficiencies and metabolic disorders do not immunise
adequately.
POSTVACCINAL REACTIONS
No systemic reactions are noticed.
The local reaction consists of a nodule that resorbs in time.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 200 or 400 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

NEWVAC LA SOTA
MODIFIED LIVE VACCINE AGAINST NEWCASTLE DISEASE
(freeze-dried)

COMPOSITION
Lentogenic Newcastle disease virus, strain La Sota from infected hen
embryos.
INDICATIONS
Specific prophylaxis of Newcastle disease in hens, turkeys, guinea-fowl,
pheasants, pigeons.
Only clinically healthy birds in good condition should be vaccinated.
The vaccination on large-scale farms should be associated with an antistress treatment.
ADMINISTRATION AND DOSAGE
Eye drop: One drop of the diluent reconstituted vaccine (250 doses/25
ml; 500 doses/50 ml) is applied into each conjunctival sac. The method is
recommended for the first two vaccinations in any rearing system.
Intramuscular vaccination: It is usually used to immunise birds in
households. The inoculation is at 0.5 ml/adult of the diluent reconstituted
vaccine (250 doses/125 ml; 500 doses/250 ml) into the pectoral muscles.
Drinking water vaccination: It is used in any rearing system by
reconstituting the vaccine in an amount of water lacking disinfectants or
detergents that ensures 20 ml of water/chicken below 30 days of age and
30 ml of water/older chicken (250 doses/5 l; 500 doses/10 l).
Aerosols vaccination: It is applied on large-scale farms by reconstituting
the vaccine in disinfectants or detergents free water so each bird
receives a vaccinal dose in 0.2-2 ml of water depending on the aerosols
generator.
The age vaccination scheme is as a rule as follows:
Vaccination I: Week 2 of life.
Vaccination II: Week 4 of life.
Vaccination III: Week 7 of life.
Vaccination IV: Week 11 of life.
The first two vaccinations are recommended to be by the
oculoconjunctival route, preferably using vaccine NEWVAC LS79. Also, in
private households, the intramuscular revaccination with NEDEVAC is
recommended after the first two vaccinations.
CONTRAINDICATIONS
Clinically diseased birds, those in full lay or during molting, those after
transfer or transport to other farms; also, 8-10 days after other
vaccinations.
POSTVACCINAL REACTIONS
Inflammatory phenomena of the eyes and respiratory apparatus may
occur post aerosol administration. These local reactions disappear in 3-4
days.
STORAGE o
At 2-8 C, protected from light.
PACKAGING
Vial of 100, 200, 250, 500, 1000 or 2000 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

NEWVAC LS79
MODIFIED LIVE VACCINE AGAINST NEWCASTLE DISEASE
(freeze-dried)

COMPOSITION
Lentogenic Newcastle disease virus, strain LS79 from infected hen
embryos.
INDICATIONS
Specific prophylaxis of Newcastle disease in hens, turkeys, guinea-fowl,
pheasants, pigeons.
Only clinically healthy birds in good condition should be vaccinated.
The vaccination on large-scale farms should be associated with an antistress treatment.
ADMINISTRATION AND DOSAGE
Eye drop: One drop of the diluent reconstituted vaccine (250 doses/25
ml; 500 doses/50 ml) is applied into each conjunctival sac. The method is
recommended for the first two vaccinations in any rearing system.
Intramuscular vaccination: It is usually used to immunise birds in
households. The inoculation is at 0.5 ml/adult of the diluent reconstituted
vaccine (250 doses/125 ml; 500 doses/250 ml) into the pectoral muscles.
Drinking water vaccination: It is used in any rearing system by
reconstituting the vaccine in an amount of water lacking disinfectants or
detergents that ensures 20 ml of water/chicken below 30 days of age and
30 ml of water/chicken over 30 days of age (250 doses/5 l; 500 doses/10
l).
Aerosols vaccination: It is applied on large-scale farms by reconstituting
the vaccine in disinfectants or detergents free water so each bird
receives a vaccinal dose in 0.2-2 ml of water depending on the aerosols
generator.
The age vaccination scheme is as a rule as follows:
Vaccination I: Week 2 of life.
Vaccination II: Week 4 of life.
Vaccination III: Week 7 of life.
Vaccination IV: Week 11 of life.
The first two vaccinations are recommended to be by the oculoconjunctival
route. Also, in private households, the intramuscular revaccination with
NEDEVAC is recommended after the first two vaccinations.
CONTRAINDICATIONS
Clinically diseased birds, those in full lay or during molting, those after
transfer and transport to other farms; also, 8-10 days after other
vaccinations.
POSTVACCINAL REACTIONS
Inflammatory phenomena of the eyes and respiratory apparatus may
occur post aerosol administration. These local reactions disappear in 3-4
days.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 100, 200, 250, 500, 1000 or 2000 doses, with diluent.
MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SINCOVAC
INACTIVATED VACCINE AGAINST EGG DROP SYNDROME

COMPOSITION
Egg drop syndrome virus in an oily adjuvant.
INDICATIONS
Prophylaxis of the egg drop syndrome. Poultry aged 111-126 days before
their transfer to the adults house will be vaccinated.
ADMINISTRATION AND DOSAGE
The vaccinal dose of 0.5 ml/bird is administered intramuscularly (the
thigh musculature, breast) or subcutaneously (the nape area).
The vaccine will be kept 2-3 hours at room temperature, before use, for
fluidisation, and vigorously agitated during use.
CONTRAINDICATIONS
Diseased poultry.
POSTVACCINAL REACTIONS
No systemic reactions are recorded. A short lasting local reaction occurs.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 200 or 400 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TETRAINVAC
OILY INACTIVATED VACCINE AGAINST NEWCASTLE DISEASE,
EGG DROP SYNDROME, INFECTIOUS BRONCHITIS
AND INFECTIOUS BURSAL DISEASE

COMPOSITION
Lentogenic Newcastle disease virus strain grown in hen embryos, the egg
drop syndrome virus, strain 127 grown in duck embryos, the infectious
bursal disease virus grown on cell cultures, and the infectious bronchitis
virus, Massachusetts strain H120.
All the viral components are formalin-inactivated.
INDICATIONS
Immunisation of the poultry previously vaccinated with modified live
vaccines against Newcastle disease, infectious bronchitis and infectious
bursal disease.
Young birds aged 17-18 weeks are vaccinated before their transfer to the
adult houses.
Revaccination is every 6 months depending on the rearing system and the
epidemiological status of the flock.
ADMINISTRATION AND DOSAGE
The 0.5ml/bird dose is subcutaneously (the upper third of the neck) or
intramuscularly (the pectoral musculature) inoculated.
The vaccine bottle should be vigorously agitated before and during
vaccination.
POSTVACCINAL REACTIONS
Sometimes a small nodule may occur at the inoculation site, that resorbs
within 1-2 weeks.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 100 or 200 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

HEMORAGIVAC
INACTIVATED VACCINE AGAINST
RABBIT HAEMORRHAGIC DISEASE

COMPOSITION
Formalin-inactivated and aluminium hydroxide-adsorbed haemorrhagic
disease virus from infected rabbits.
INDICATIONS
Preventive and emergency immunisation of rabbits.
ADMINISTRATION AND DOSAGE
Subcutaneously at 1 ml to over 60 days old rabbits.
The maintenance vaccination is at the same dose every 6 months. The
bottle should be agitated before inoculation for the vaccine
homogenisation.
CONTRAINDICATIONS
Rabbits below 60 days of age.
Females during the second half of gestation.
Rabbitries where other infectious and contagious diseases are present.
POSTVACCINAL REACTIONS
A small flat oedema may occur 1-2 days post vaccination that abates
leaving behind a nodule of cca 0.5 cm in diameter.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 5, 10, 20, 40 or 80 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LEPTOCANIVAC
VACCINE AGAINST CARNIVORES LEPTOSPIROSIS

COMPOSITION
Heat- and sodium merthiolate-inactivated Leptospira canicola and
icterohaemorrhagiae.
INDICATIONS
Preventive or emergency immunisation of carnivores.
It may be administered alone or associated with the antiviral vaccine as a
polyvalent vaccine.
ADMINISTRATION AND DOSAGE
1 ml inoculated by the subcutaneous route.
Preventive purposes: Two vaccinations 21 days apart.
The maintenance vaccinations are annual.
Emergency purposes: The infected or suspect animals in active
leptospirosis outbreaks are isolated, treated for the infection, and then
applied with the same vaccination scheme.
CONTRAINDICATIONS
Carnivores during the last gestational month.
Animals under stress.
Animals during the course of infectious and contagious diseases.
POSTVACCINAL REACTIONS
Sometimes nodules may occur at the inoculation site, that resorb in time.
Under the current practice conditions, the inoculation of certain vaccines
may induce, irrespective of the manufacturer, anaphylactic reactions to
some animals. The animals should be observed for 1-2 hours post
vaccination; if necessary, an antihistaminic will be administered.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 1, 2, 5, 10 or 20 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PARVOCAN
MODIFIED LIVE VACCINE AGAINST CANINE PARVOVIROSIS

COMPOSITION
Parvovirus, strain IP99 (Pasteur Institute 99) (freeze-dried) and strain Bb
(liquid).
INDICATIONS
Dogs: Prevention of parvovirosis.
ADMINISTRATION AND DOSAGE
1 ml subcutaneously or intramuscularly administered.
The booster is with TRIVIROCAN 2-3 weeks later.
CONTRAINDICATIONS
Below 6 weeks of age unless the puppies originate from unvaccinated
dams.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial with the freeze-dried component and a bottle with the liquid one
equivalent to a vaccinal dose.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PENTACAN
VACCINE AGAINST CANINE DISTEMPER, INFECTIOUS
HEPATITIS, PARVOVIROSIS AND LEPTOSPIROSIS

COMPOSITION
1 dose contains:
Distemper virus
103 CPD50
2.5
Canine adenovirus 2
10 CPD50
Canine parvovirus
106 DCI50
Leptospira icterohaemorrhagiae and canicola
1ml
INDICATIONS
PREVENTION OF CANINE DISTEMPER, INFECTIOUS HEPATITIS,
PARVOVIROSIS AND LEPTOSPIROSIS.
ADMINISTRATION AND DOSAGE
The vaccinal dose is obtained by solubilising the freeze-dried component
with the liquid Leptospira component. The pellet once completely
solubilised, the vaccine is inoculated subcutaneously or intramuscularly at
minimum 6 weeks of age. The booster is 15-20 days post vaccination I,
and once a year thereafter.
The immunity sets in 10-15 days since the booster, being maintained by
yearly vaccinations.
CONTRAINDICATIONS
Puppies below 6 weeks of age, excepting those born to unvaccinated dams.
Pregnant females.
STORAGE
Both the vial and the bottle should be kept at 4-8C.
PACKAGING
Box with 25 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

RABIVAC E
MODIFIED LIVE VACCINE AGAINST RABIES
(freeze-dried)

COMPOSITION
Fixed rabies virus, strain Era grown on cell cultures.
INDICATIONS
Preventively for the immunisation of carnivores.
ADMINISTRATION AND DOSAGE
Intramuscularly at 1 ml irrespective of the animals species. In the disease
outbreak the doses are as follows:
Dogs, cats: 1 ml.
Generally, the vaccination is recommended starting with 6 months of age
with annual repetition.
With the young animals born to unvaccinated dams, it may be
administered at 2-3 months of age, with repetition at 6 months of age.
CONTRAINDICATIONS
Diseased animals.
PRECAUTIONS
The vaccine is to be used, after dilution, within maximum 1 hour and 2
hours in summer and winter respectively.
These intervals once elapsed, the diluted vaccine must be discarded.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 1, 5 or 10 doses, with diluent.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TRIVIROCAN
MODIFIED LIVE VACCINE AGAINST DISTEMPER,
CANINE HEPATITIS AND PARVOVIROSIS
(freeze-dried)

COMPOSITION
CDV, CAV2 and Parvovirus, strain IP99 (under a freeze-dried form) and
Parvovirus, strain Bb (under a liquid form).
INDICATIONS
Prevention of the canine parvovirosis and hepatitis, distemper.
Vaccination is at 6 weeks or 2 months of age, i.e. 15-20 days post the
vaccination with PARVOCAN, a modified live vaccine against canine
parvovirosis.
ADMINISTRATION AND DOSAGE
The pellet completely dissolved in the 1 ml of the accompanying liquid is
subcutaneously or intramuscularly inoculated.
The booster is 15-20 days later, and once a year thereafter.
CONTRAINDICATIONS
Earlier than 2 months of age particularly with the puppies born to
vaccinated dams.
Pregnant females.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial with the freeze-dried component and a bottle with the liquid
component, representing a vaccinal dose.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ACETOSTOP
ORAL SOLUTION

COMPOSITION
Potassium iodide
0.2 g
Cobalt sulphate
0.1 g
Glycerine
25.0 g
Propyleneglycol
43.0 g
Excipient
up to 100.0 ml
PHARMACOTHERAPEUTIC ACTIVITY
The product allows glycaemia to be maintained and the high blood level of
the ketone bodies to be diminished in the cattle and sheep with
acetonaemia. This effect is due to its associated components:
Propyleneglycol rapidly changes into glucose contributing to the
carbohydrates absorption, while also being a very good vehicle for the
other active ingredients; glycerine is also a precursor of neoglucogenesis
phenomena; potassium iodide ensures the iodine amount necessary to
stimulate the thyroid function and, implicitly, the metabolic process; cobalt
permits possible vitamin B12 deficiencies to which acetonaemic animals
are predisposed to be controlled.
INDICATIONS
Cattle, sheep, goats: Acetonaemia (lactating cows), gestation toxaemia
(ewes), indigestion, nutritional deficiencies.
Supporting therapy in the post-parturition fever, myopathies, tetanias,
parasitic and microbial conditions.
ADMINISTRATION AND DOSAGE
Orally, in the drinking water or in the feed.
Lactating cows
Preventively: 50 ml twice a day for 4 days.
Curatively: 250 ml, in the morning and evening for 4 days, followed by
125 ml in the morning and evening for another 3 days.
Sheep, goats
Curatively: 125 ml/day for 4 days.
If necessary, the treatment will be repeated.
WITHDRAWAL TIME
Milk: 4 milkings.
Meat, organs: 3 days.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 500 or 1000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

AD3E
INJECTABLE SOLUTION

COMPOSITION
Vitamin A (palmitate)
10 million IU
1 million IU
Vitamin
D3
(cholecalciferol)
Vitamin E (acetate)
5g
Excipient
up to 100 ml
PHARMACOTHERAPEUTIC ACTIVITY
The AD3E vitamin complex contains vitamins that are indispensable to the
metabolic processes, and acts as a biostimulator, increasing the cell
epithelia and membranes resistance to pathogenic microorganisms.
Vitamin A represents the epi- and endothelial protective factor that
prevents infections, increases the body resistance, stimulates the growth
and egg laying. Vitamin D3 is indispensable to the skeletal and egg shell
development; it participates in regulating the calcium-phosphorus balance,
intervenes in the carbohydrates metabolism determining the increase in
the liver and muscles glycogen. Vitamin E prevents the oxidation of the
body lipids and of the feed fats; its activity also relates to the amino acids
and proteins transport in the body. It potentiates the activity of vitamin A.
INDICATIONS
Prophylaxis and treatment of vitamin deficiencies, rickets and
osteomalacia, as well as for the improvement of deficient feeding ratios.
The AD3E vitamin complex is used to increase the body resistance to
infections, to improve the overall condition, to reduce the transport stress,
and to improve prolificacy in breeding animals.
ADMINISTRATION AND DOSAGE
Intramuscularly or subcutaneously at the following doses per animal:
Horses, cattle: 10-12.5 ml
Calves, foals, pigs: 2-5 ml
Young pigs: 2-4 ml
Sheep, goats: 1.5-2.5 ml
Lambs, kids, suckling pigs, breeding rabbits: 0.5-1 ml
Dogs, cats: 1-2 ml
If necessary, the dose may be repeated after 3 weeks.
CONTRAINDICATIONS
If administered at high doses or for a long time period, toxic phenomena
such as skin and mucosa colouration, anaemia and leucopaenia may be
recorded.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 50 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

AMINOPHENAZONE
SUPPOSITORIES

COMPOSITION
1 suppository contains:
Aminophenazone
0.1 g
PHARMACOTHERAPEUTIC ACTIVITY
Aminophenazone is a nonacidic compound derived from pyrazole-5-one. It
has analgetic, anti-inflammatory, antipyretic and weakly antispastic
effects.
INDICATIONS
Dogs: Prolonged feverish conditions, neuralgias and myalgias.
ADMINISTRATION AND DOSAGE
Rectally: 1-3 suppositories/day until the clinical signs disappearance.
CONTRAINDICATIONS
Agranulocytosis, leucopaenia, granulocytopaenia, intolerance to
pyrazolones.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box of 2 blister foils x 6 suppositories.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

AMINOVIT
TABLETS

COMPOSITION
1 tablet contains:
Methionine
0.0275 g
Inositol
0.0275 g
Choline
0.0205 g
Biotin (vitamin H) 0.0003 g
Calcium pantothenate
0.0075 g
PHARMACOTHERAPEUTIC ACTIVITY
Methionine, inositol and choline are used associatedly due to their lipo- and
hepatotropic properties. Methionine (a sulphurated amino acid) and inositol
turn into choline, a metabolite that is indispensable to the organism. Choline
intervenes in the phospholipids synthesis. Biotin stimulates the growth of the
skin, mesenchymatous and nervous tissues. Deficiencies are usually
associated with dermatites and alopecias. Vitamin H allows these symptoms
to disappear, while the pantothenic acid plays an important role in hair
regeneration.
INDICATIONS
Dogs, cats: Hepatoprotector.
Supporting treatment in skin and horny processes conditions.
ADMINISTRATION AND DOSAGE
Orally, as follows:
Small dogs, cats: 1 tablet/day.
Medium sized dogs: 2 tablets/day.
Large dogs: 3 tablets/day.
The treatment lasts 10 days or as directed by the veterinarian.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Bottle of 20-100 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

AMOXAN 40
TABLETS

COMPOSITION
1 tablet contains:
Amoxicillin trihydrate
0.040 g
PHARMACOTHERAPEUTIC ACTIVITY
The product contains amoxicillin trihydrate, a semisynthetic penicillin of
broad spectrum against Gram-positive and -negative bacteria. It is stable
in an acid medium; administered orally, it is 80-90% absorbed thus
ensuring high concentrations both in the serum and tissues. It has a
manifest pulmonary tropism, the therapeutical response being quick as the
binding to the plasma proteins is weak. It is bile- and urine-excreted.
INDICATIONS
Dogs, cats: Bacterial infections of the respiratory, digestive and uro-genital
apparatus, of the otorhinolaryngological and articular areas, as well as
viral diseases-associated secondary infections.
ADMINISTRATION AND DOSAGE
Orally, either as such at the tongue basis, or mixed in the feed.
Dose: 10 mg of amoxicillin/kg of live weight (1 tablet/4 kg of live weight)
twice a day for minimum 5 days.
CONTRAINDICATIONS
Allergy to penicillin.
Rabbits, guinea-pigs, hamsters.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Bottle of 20-50 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

AMPICILLIN 100
TABLETS

COMPOSITION
1 tablet contains:
Ampicillin trihydrate 100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Ampicillin is a semisynthetic penicillin that is bactericidal against Grampositive germs (Corynebacterium diphtheriae, Bacillus anthracis,
Diplococcus pneumoniae, Streptococcus spp., Staphylococcus spp.) and
Gram-negative ones (Escherichia coli, Proteus vulgaris and mirabilis,
Salmonella spp., Shigella spp., Haemophilus spp., Brucella spp.). Orally
administered, it readily spreads into the tissues, and less so into the
serous membranes, nervous system, crystalline lens and mammary
tissue. It resists the action of the gastric juice, being readily absorbed from
the digestive tract. It accumulates at higher concentrations in the liver and
kidneys than in the blood, and it is actively excreted through the kidneys
and less so through the bile and milk.
INDICATIONS
Dogs,
cats:
Treatment
of
respiratory
infections
(tonsillites,
bronchopneumonias), infections of the gastrointestinal and of the urogenital apparatus, skin infections (dermatites, abscesses), infections of the
perianal glands of the dog, post surgery infections.
ADMINISTRATION AND DOSAGE
Orally, as follows :
Dogs: 10-25 mg / kg of body weight (1 tablet / 4-10 kg of body weight).
Cats: 10-25 mg/kg of body weight.
The treatment is repeated every 6-8 hours for 3-5 days.
CONTRAINDICATIONS
Penicillin-allergic animals.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Bottle of 50 or 100 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

AMPICILLIN 250
TABLETS

COMPOSITION
1 tablet contains:
Ampicillin (as trihydrate)
250 mg
PHARMACOTHERAPEUTIC ACTIVITY
Ampicillin is a semisynthetic penicillin that is bactericidal against Grampositive germs (Corynebacterium diphtheriae, Bacillus anthracis,
Diplococcus pneumoniae, Streptococcus spp., Staphylococcus spp.) and
Gram-negative ones (Escherichia coli, Proteus vulgaris and mirabilis,
Salmonella spp., Shigella spp., Haemophilus spp., Brucella spp.). Orally
administered, it readily spreads into the tissues, and less so into the
serous membranes, nervous system, crystalline lens and mammary
tissue. It resists the action of the gastric juice, being readily absorbed from
the digestive tract. It accumulates at higher concentrations in the liver and
kidneys than in the blood, and it is actively excreted through the kidneys
and less so through the bile and milk.
INDICATIONS
Dogs,
cats:
Treatment
of
respiratory
infections
(tonsillites,
bronchopneumonias), infections of the gastrointestinal and of the urogenital apparatus, skin infections (dermatites, abscesses), infections of the
perianal glands of the dog, post surgery infections.
ADMINISTRATION AND DOSAGE
Orally, as follows:
Dogs: 10-25 mg / kg of body weight (1 tablet/10-25 kg of body weight).
Cats: 10-25 mg/kg of body weight.
The treatment is repeated every 6-8 hours for 3-5 days.
CONTRAINDICATIONS
Penicillin-allergic animals.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Bottle of 50 or 100 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ANEMIN P
POWDER

COMPOSITION
Iron oxalate
40 g
Copper sulphate
1.6 g
Cobalt chloride
0.2 g
Glucose
up to 100 g
PHARMACOTHERAPEUTIC ACTIVITY
The product contains Fe2+ as well as other trace elements (cobalt, copper)
and glucose as an energetic and antitoxic factor also improving the
gustatory properties. The bivalent iron in the ferrous oxalate administered
orally is readily absorbable even in the case of very young pigs, the daily
iron intake by this route being the natural one. Approximately 1 g of the
1:1 mixture of ANEMIN P and maize flour ensures the iron amount sufficient
for a normal haemoglobinogenesis. The other elements facilitate the
haemoglobin synthesis, while also stimulating the haemoglobin formation.
INDICATIONS
Prevention and treatment of anaemia in the piglets on farms where
anaemia is diagnosed after treatments based on iron dextran products. It
does not exclude treatments with iron dextran-containing products. The
treatment with ANEMIN P is an adjuvant in infections, of the digestive and
respiratory apparatus in particular. Its administration during the maximum
growth period, to animals in advanced pregnancy or to those recently
farrowed improves the overall condition.
ADMINISTRATION AND DOSAGE
It is mixed 1:1 with maize flour and administered as early as day 1 of life at
1 g of mixture/piglet/day. 12-14 days later the mixture is added to the
compound feed, the doses progressively increasing from 2 to 5 g of
mixture/piglet/day (20-50 g/day for a 10 piglets box). It is recommended up
to 30-32 days of age. It may be used in other pig categories whenever
anaemia episodes are recorded as follows:
Young pigs: 7 g of the 1:1 mixture/pig/day for 20-30 days.
Sows (20 days before and/or after farrowing): 40 g of the 1:1
mixture/sow/day.
CONTRAINDICATIONS
Diarrhoeic pigs; the treatment may be continued after recovery.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Aluminium foil sachet of 50-1000 g, or hydrophobic paper sack of 1-25 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ANTIMYCOTIC OINTMENT
OINTMENT

COMPOSITION
Thiuram
1g
Excipient
up to 100 g
PHARMACOTHERAPEUTIC ACTIVITY
The active ingredient blocks the synthesis of some components necessary
for the survival of the mycetes cell. It is active against some phyto- or
zooparasitic fungi, and those involved in the degradation or animal- or
plant-derived products. The toxicity to the animal is reduced, the active
ingredient falling into toxicity Group III.
INDICATIONS
Cattle, horses, pigs, dogs, cats, poultry: Treatment of dermatomycoses
induced by various species of fungi, those of the Trichophyton and
Microsporum genera in particular.
ADMINISTRATION
Thin lesional and perilesional painting 2-3 times a day at intervals of 3-5
days.
As the treatment efficacy is influenced by the crusts thickness, their
previous removal facilitates the product penetration into the affected
surface.
CONTRAINDICATIONS
Application on the mucosae, the conjunctival one in particular.
PRECAUTIONS
Being a little irritant, its application on the facial lesions should be
precautiously made.
In case of intolerance, a very rare phenomenon, the treatment will be
discontinued.
WITHDRAWAL TIME
Meat: 5 days since the treatment.
STORAGE
At 4-10oC, protected from light and humidity.
PACKAGING
Metallic tube of 60 g, or plastic box of 250 or 500 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ASCOMICIN
OINTMENT

COMPOSITION
Streptomycin base
20 mg
Penicillin G
20,000 IU
Lipophil ointment base
up to 1 g
PHARMACOTHERAPEUTIC ACTIVITY
The association of two bactericidal antibiotics makes the product potent
against many Gram-positive and -negative germs (staphylococci,
streptococci, colibacilli, pasteurellas, other opportunistic germs).
INDICATIONS
Infected wounds, abscesses, furuncles, fistulae, skin lesions, ocular
conditions, external otites, mastites.
ADMINISTRATION AND DOSAGE
Local infections: Once or several times a day covering the entire wound,
until recovery.
Ocular infections: Once or several times into the conjunctival sac until
recovery, or as directed by the veterinarian.
Mastites: The diseased quarter is milked and the galactophorous duct is
then applied with of the tube; the udder is massaged and left unmilked
for 12-18 hours. The treatment is applied daily until the symptoms
disappearance.
PRECAUTIONS
The diseased animals will be isolated.
The milkers hands will be washed and disinfected before milking.
The tip accompanying the tube will be boiled for sterilisation.
The tube will be kept in warm water before usage in winter time.
STORAGE
At 2-8oC, protected from light and humidity.
PACKAGING
Aluminium tube of 40 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

AVOMEC
INJECTABLE SOLUTION
COMPOSITION
Ivermectin
1%
PHARMACOTHERAPEUTIC ACTIVITY
The product is an antiparasitic very efficient against both internal and external parasites. It first
paralysis and then kills the nematodes, arachnids and parasitic insects, inhibiting the transmission
of the nervous signals from the ventral cords neurons to the motor ones by stimulating the release
of the gamma-amino-butyric acid (GABA) that is an inhibitor of the nervous transmission from the
parasympathetic endings. At therapeutic doses, the substance is not noxious for the animals, as
the GABA is not present in their central nervous system. This explains the very good tolerance of
the product.
INDICATIONS
Cattle, sheep, swine: Prevention and control of endo- and ectoparasitoses.
Cattle
Gastrointestinal and pulmonary strongyles: Ostertagia spp., Haemonchus spp. (adults, L3, L4),
Trichostrongylus spp., Cooperia spp., Oesophagostomum radiatum (adults, L3, L4), Nematodirus spp.
(adults), Strongyloides papillosus (adults), Neoascaris vitulorum (adults), Dictyocalus viviparus (adults,
L4, inhibited stages).
Other round worms: Parafilaria bovicola, Thelazia spp. (adults).
Larval hypodermas: Hypoderma spp.
Lice: Linognathus vituli, Haematopinus eurysternus, Damalinia bovis.
Acarians: Sarcoptes scabiei var. bovis, Chorioptes bovis.
Mites
Sheep
Gastrointestinal and pulmonary strongyles: Haemonchus contortus (adults, L3, L4), Ostertagia
circumcincta (adults, L3, L4), Trichostrongylus axei (adults), Nematodirus filicollis (adults, L4),
Oesophagostomum spp. (adults, L3, L4), Chabertia ovina (adults, L3, L4), Trichocephalus ovis
(adults), Strongyloides papillosus (L3, L4), Dictyocaulus filaria (adults, L3, L4), Protostrongylus spp.
(adults).
Nasal helminths: Oestrus ovis.
Acarians: Sarcoptes scabiei, Psoroptes scabiei var. ovis.
Swine
Gastrointestinal and pulmonary strongyles: Ascaris suum (adults, L4), Hyostrongylus spp. (adults,
L4), Oesophagostomum spp. (adults, L4), Strongyloides spp. (adults), Trichocephalus suis
(adults), Metastrongylus spp. (adults).
Acarians: Sarcoptes scabiei var. suis.
Lice: Haematopinus suis.
ADMINISTRATION AND DOSAGE
Subcutaneously, as follows:
Cattle, sheep: 200 mcg of ivermectin/kg of live weight (1 ml of AVOMEC/50 kg of live weight).
Pigs: 300 mcg of ivermectin/kg of live weight (1 ml of AVOMEC/33 kg of live weight).
PRECAUTIONS
It should not be injected intramuscularly or intravenously.
The bottles of product will be under permanent protection from light in carton boxes.
It should be kept out of the reach of children.
WITHDRAWAL TIME
Meat: 28 days since the last administration.
Milk: 21 days since the last administration.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Brown bottle of 10, 20, 50, 100 or 250 ml.
MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BRONHOSTIM
PHYTOTHERAPEUTIC TINCTURE

COMPOSITION
Essential oils, polyphenolic heterozides and tannins dissolved in 50o
alcohol and resulted from the maceration of road-weed leaves, basil
flowers, black radish roots.
PHARMACOTHERAPEUTIC ACTIVITY
The product has an emollient, fluidising and expectorant effect on the
bronchial secretions, as well as an anti-inflammatory, healing and
bacteriostatic effect. Due to the presence of phenols, it has a
biostimulating ability inducing the quicker reduction of the clinical signs in
the respiratory conditions of the young animals.
INDICATIONS
Adjuvant in the anti-infectious treatments of the respiratory apparatus. A
potentiation of the antibiotics effect was also recorded in the aetiologic
treatment.
ADMINISTRATION AND DOSAGE
Piglets: A 1/10 dilution is made in boiled and cooled water or tea, of
which 2-3 ml/animal is dispenser-administered twice a day for 3-5 days.
Calves: 10 ml/animal twice a day for 3-5 days depending on the disease
course. The administration is in milk or tea, by the feeding bottle or
bucket.
Lambs: 3 ml/animal for 3-5 days by the feeding bottle, mixed with 50-100
ml of milk or tea.
In the case of farms where respiratory conditions are frequent in the young
animals, the product may also be preventively administered once a day at
10 and 3 ml to calves and lambs respectively, and at 2 ml of the 1/10
dilution to piglets.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Brown bottle of 200 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

CAFFEINE - SODIUM BENZOATE


INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Caffeine p.a.
125 mg
Sodium benzoate p.a.
125 mg
PHARMACOTHERAPEUTIC ACTIVITY
Caffeine is an alkaloid that stimulates the central nervous system,
increasing the sensory acuity. It increases the contraction ability of the
heart improving its rate, produces vasoconstriction of the splanchnic area,
dilation of the coronary, cerebral and renal vessels. It improves the
respiratory centre and the diuretic activities by diminishing the tubules
resorption (there is a risk of inhibiting diuresis by its activity on the nervous
central system).
INDICATIONS
Food-borne and drug-induced poisonings, after laborious parturitions,
dystocias, sapraemic toxicoses, septicaemias, pyemias, pneumonias,
bronchopneumonias, peritonites, infectious and parasitic diseases.
ADMINISTRATION AND DOSAGE
Usually, by the subcutaneous route as follows:
Large animals: 8-20 ml/day in several doses (one dose of maximum 5-10
ml).
Sheep, goats, pigs: 1-5 ml/day in several doses (one dose of maximum
1-3 ml).
Carnivores: 1-2 ml/day in several doses (one dose of maximum 0.5-1
ml).
Collapse and intoxications of and as a diuretic for large animals: 10-25
ml diluted in 10-25 ml of physiological saline or glucose-added serum, by
the intravenous route.
CONTRAINDICATIONS
Agitation, tachyhardia, strychnine poisoning.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Brown bottle of 10 or 20 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

CALCIUM BOROGLUCONATE
INJECTABILE SOLUTION

COMPOSITION
Injectable calcium gluconate
38 g
Boric acid
6.5 g
Magnesium chloride
6.0 g
Excipient
up to 1000 ml
PHARMACOTHERAPEUTIC ACTIVITY
The product disperses well into the tissues, providing the organism with
important amounts of calcium, magnesium and energy. Calcium
participates in the skeleton formation, controls the cell permeability and
blood clotting. The calcium deficiency influences the reproduction in cattle,
sheep, swine, carnivores and coypu often inducing infertility; in males, it
induces severe disturbances of the spermatogenesis.
INDICATIONS
Ante- and post-partum pareses and paraplegias, hypocalcaemia, tetany,
allergies, toxicoses, rickets, osteomalacia, acetonuria, haemorrhagical
conditions, anaemias, postvaccinal accidents, abortions, vaginal and
uterine prolapse, caesarians, etc.
ADMINISTRATION AND DOSAGE
Intravenously, intramuscularly and subcutaneously at several sites, alone
or associated with vitamins A, C, and the vitamin B complex:
Large animals: 20-30 ml/10 kg of body weight.
Swine, calves, sheep: 10-30 ml by the subcutaneous route.
Piglets, dogs, cats, coypu: 1-2 ml by the subcutaneous route.
The administration may be daily or every 2-3 days in small and mediumsized animals with rickets, gastroenteritis, nutritional disorders, etc. in
particular, and 1-3 times, depending on the situation, in large animals
especially with ante-partum paraplegias.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 20, 50, 100, 200 or 400 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

CALCIUM - MAGNESIUM

...
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Calcium chloride
100 mg
Magnesium chloride 250 mg
PHARMACOTHERAPEUTIC ACTIVITY
The calcium ions intervene in the ossification processes, diminish the cellular and
vascular permeability preventing the formation of oedemata, have an anti-allergic
and -inflammatory effect and a tonic activity on the heart and central nervous
system, strengthen the uterine musculature, participate in the blood clotting
process, activate trypsin, stimulate phagocytosis, and act as a diuretic. The
magnesium ions act antagonistically to the calcium ones: they depress the
central nervous system and heart activity, reduce the intestinal tonus and
peristalsis, relax the involuntary uterine musculature, and decrease the arterial
pressure. The two ions association ensures a moderate activity by reducing the
effects of the two elements.
INDICATIONS
Tetanias, spasmophilias, ante- and post-partum pareses and paraplegias, post
partum fever, serum disease, anaphylactias, hypocalcaemias. It is a tonic of the
central nervous system and myocardium.
ADMINISTRATION AND DOSAGE
Strictly intravenously (slowly) as follows:
Large animals: 100-400 ml (10-40 g of calcium chloride), depending on the
animals weight and condition severity.
Medium-sized animals: 20-120 ml (2-12 g of calcium chloride).
Small animals: 10-20 ml (1-2 g of calcium chloride).
The dose may be repeated after 24 hours.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 20, 50, 100, 250 or 500 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

CANIDER U
OINTMENT

COMPOSITION
0.2% amitraz and 0.5% neomycin sulphate incorporated into a hydrophilic
ointment base.
PHARMACOTHERAPEUTIC ACTIVITY
Amitraz acts as a parasiticide; it inhibits monoaminoxidases and blocks
the neuromuscular transmission. Neomycin is an antibiotic active against
various Gram-positive and -negative germs: Staphylococcus aureus
(strains resistant to other antibiotics included), Streptococcus pneumoniae
and pyogenes, Escherichia coli, Klebsiella, Haemophilus influenzae,
Salmonella typhi, Shigella and Mycobacterium tuberculosis (streptomycinresistant strains included). It has no antiviral activity. The ointment base
used favours the active ingredient penetration into the skins deep
structures where the parasites are located. It ensures, at the same time, a
prolonged contact between the active ingredient and the parasite.
INDICATIONS
Canine demodicosis.
ADMINISTRATION AND DOSAGE
It is applied on the lesioned areas without necessarily removing the crusts,
while slightly massaging the region to favour the ointment penetration.
Three treatments are recommended at a 2 days interval; depending on the
lesions evolution, the fourth treatment is applied 7 days post the last
administration.
PRECAUTIONS
Gloves should be worn.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Tube of 25, 50 or 100 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

CLORODIN U
OINTMENT

COMPOSITION
Cetylpyridinium chloride
0.005 g
Chlorhexidine
0.001 g
Washable base
up to 1.000 g
PHARMACOTHERAPEUTIC ACTIVITY
The cetylpyridinium chloride is antimicrobial against Gram-positive and negative germs. It decreases the superficial pressure, increases the
membranes permeability and lyses the microbial cells. Chlorhexidine is an
antiseptic active against the vegetative forms of many Gram-positive and negative germs. It immediately reduces the microbial flora on the skin to a
much more extent than some iodophors. The product protects, due to the
ointment base, the udder skin maintaining it supple.
INDICATIONS
Prevention of the udder inflammations, and the treatment of the udder
pyogenic infections.
ADMINISTRATION AND DOSAGE
Following milking the cream is applied on the udder massaging very well
to facilitate the penetration into the epidermis.
PRECAUTIONS
Contact with the eyes should be avoided.
The udder should be well washed before milking.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Plastic box of 25-1000 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

CLOROSTATIC
OTIC SOLUTION

COMPOSITION
Chloramphenicol
0.50 g
Fluocinolone (as acetate)
0.05 g
Excipient
up to 100.00 g
PHARMACOTHERAPEUTIC ACTIVITY
The product is anti-inflammatory and -allergic due to fluocinolone, and
bacteriostatic and bactericidal due to chloramphenicol. The microorganisms
inducing auricular infections that are sensitive to chloramphenicol are
Staphylococcus aureus, Streptococcus haemolyticus, Pseudomonas
aeruginosa, Escherichia coli and Proteus vulgaris.
INDICATIONS
Dogs, cats: Chloramphenicol-sensitive germs induced otitis externa and
media purulenta. Chloramphenicol prevents the synthesis of the bacterial
proteins.
ADMINISTRATION AND DOSAGE
The external auditory meatus is cleaned with OTTO-CLEANS, a
cerumenolytic solution, and then instillated with CLOROSTATIC.
Dogs: 4-6 drops, 2-3 times a day.
Cats: 2-4 drops, 2-3 times a day.
CONTRAINDICATIONS
Dogs or cats allergic to one of the product components.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Dropper bottle of 7.5 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

COCCISTOP S
ORAL SOLUTION

COMPOSITION
Sulfaquinoxaline (as sodium salt)
20 %
PHARMACOTHERAPEUTIC ACTIVITY
Sulfaquinoxaline is a coccidiostatic sulphonamide acting against the
coccidial metabolism by limiting the action of the paraaminobenzoic acid in
their cells. It is active against the coccidias of the Eimeridae family namely
Eimeria acervulina, E. necatrix, E. mitis, E. tenella, E. brunetti of chicks,
against E. meleagridis and E. adenoides of turkey poults, and against E.
perforans, E. intestinalis, E. magna of rabbits. Sulphonamides are
metabolised in the liver, being excreted through the kidneys.
INDICATIONS
Prophylaxis and treatment of all coccidioses found in chicks, turkey poults
and rabbits.
Efficient in the treatment of hen and turkey pasteurellosis and pullorum
disease.
ADMINISTRATION AND DOSAGE
Chicks (5-6 days to 6-10 weeks of age)
Prophylactically: 15 ml in 11 l of drinking water for 2 consecutive days,
followed by 5 days breaks.
Curatively: 45 ml in 22 l of drinking water for 2-3 days, followed by a 3
day break. It is again administered for 2 days at 15 ml in 11 l of drinking
water followed by a 2-day break, and then by a last treatment with 15 ml
in 11 l of drinking water.
Turkey poults (5-6 days to 7 weeks of age)
Prophylactically: 15 ml in 11 l of drinking water for 1 day, followed by 4day breaks.
Curatively: 15 ml in 11 l of drinking water in 3 series of 2 consecutive
days each, with 3 days of break in between.
Hens, turkeys (pasteurellosis, pullorum disease)
Curatively: 45 ml in 22 l of drinking water for 3 days. The treatment is
resumed 3 days later at 15 ml in 11 l of drinking water for 2 days.
PRECAUTIONS
The concentrations recommended will be observed as to avoid
intoxications.
The solution will be administered, in hot weather, in the morning drinking
water; the water consumption will be, for the rest of the day, as usual.
The bottle will be shaken before use !
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 100, 500, 1000 or 5000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

DEO - VET
DISINFECTING DETERGENT

COMPOSITION
Cationic tensio-active substance (alkyl C10-C18
dimethylbenzylammonium chloride)
4%
Non ionic tensio-active substances
up to 100 %
PHARMACOTHERAPEUTIC ACTIVITY
The product is bactericidal, fungicidal and virucidal against a varied
microbial flora (Escherichia coli, Aspergillus spp., Penicillium spp.,
Saccharomyces cerevisiae, Staphylococcus epidermidis, Staphylococcus
aureus, Streptococcus pyogenes, Proteus vulgaris, Shigella spp.,
Trichophyton interdigitale, Candida albicans, various viruses).
INDICATIONS
Cleansing and disinfection of various surfaces (wall and floor tiles,
plastics, metal, glass) as to inhibit and eliminate the mould growth and
odour respectively.
USES
A fresh 2.5 % solution is prepared by dissolving 25 ml in 1000 ml of water.
Cleansing, disinfection, odour removal: The solution is applied on
surfaces by means of a sponge, cloth, or sprayer.
Mould removal: The solution is applied on mouldy walls or floors, allowed
a 30 minutes contact and rinsed in water; a new amount of solution is
applied and left to dry. The application is weekly or whenever the mould
reappears.
PRECAUTIONS
It will not be combined with anionic tensio-active substances (common
detergents, soap).
It will not be combined with other disinfectants (hydrogen peroxide,
sodium hypochlorite) or with strongly alkaline substances.
The product ingestion and food contamination will be avoided.
The product will be kept out of the reach of children.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 1, 2, 5 or 30 l.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

DERMOSEPT
OINTMENT

COMPOSITION
Ichtyol
10 g
Zinc oxide
15 g
Excipient
up to 100 g
PHARMACOTHERAPEUTIC ACTIVITY
The organic and inorganic sulphur in ichtyol ensures the product reducing,
antiseptic, keratoplastic and antipruriginous properties. Due to the zinc
oxide, the product is a good skin protector. Upon performing its adsorbing
action, it slowly solubilises in the acid medium of inflammations becoming
slightly astringent.
INDICATIONS
Treatment of skin conditions: Burns, chilblains, furunculosis,
pododermatites, paronychias, superinfected sores.
ADMINISTRATION AND DOSAGE
Once the affected sites are cleaned, they are thinly applied with the
ointment 2-3 times a day until lesions remittal.
CONTRAINDICATIONS
Mucosa, animals that are tar-hypersensitive.
WITHDRAWAL TIME
Meat: 15 days since the last administration on extensive areas.
STORAGE
At 2-8oC.
PACKAGING
Tube of 40 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

DEXOGEN
OTIC OILY SUSPENSION

COMPOSITION
1 ml contains:
Gentamycin (as sulphate)
5 mg
Dexamethasone
0.85 mg
Albendazole
34 mg
PHARMACOTHERAPEUTIC ACTIVITY
The product is antibacterial due to gentamycin that is the most active
antibiotic against the microbial flora present in otites, and antiinflammatory due to dexamethasone.
INDICATIONS
Dogs, cats: Treatment of auricular acute or chronic inflammatory or
allergic conditions.
ADMINISTRATION
Auricular instillations: 4-6 drops administered twice a day for 5-6 days
after the ears are cleaned with OTTO-CLEANS, a cerumenolytic solution.
PRECAUTIONS
Dogs or cats allergic to one of the components.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Dropper bottle of 20 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

DIAZINOL
EXTERNAL ANTIPARASITIC
COMPOSITION
Diazinone emulsifiable concentrate
60 %
PHARMACOTHERAPEUTIC ACTIVITY
Diazinone is a nonsystemic synthetic organophosphoric compound that is parasiticidal against
external parasites as it blocks acetylcholine-esterase. Acetylcholine remains unhydrolysed and
therefore accumulates inducing the paralysis of the parasites neuromuscular system. Diazinone is
a toxicity group III member.
INDICATIONS
Cattle, sheep, goats, swine: Prophylaxis and control of all ectoparasites (mites, lice, muscids) and
of those inducing scabies (the sarcoptic, psoroptic, chorioptic and demodectic ones).
ADMINISTRATION AND DOSAGE
The solution should be prepared and used on the very same day.
The treatment is repeated 14 days later in case of need, and 7-9 days since the first dipping in case
of scabietic animals.
Cattle
Spraying: 20ml/20 l of water (600 ppm). The entire animals body should be sprayed.
Local treatment: 5 ml/l of water (3000 ppm).
Sheep, goats
Dipping: 420 ml/1000 l of water (250 ppm). The replenishment is with a 250 ml/200 l of water (750
ppm). The solution height should be 70 and 100 cm for the lambs and young sheep and for the
adults respectively. It is essential to maintain the concentration by replenishing when the volume
drops by 10%. The animals should be completely dipped at least once.
Local treatment: 5 ml/l of water (3000 ppm).
Spraying: 20 ml/20 l of water (600 ppm).
Pigs
Spraying: 10 ml/24 l of water (250 ppm).
Houses
Spraying: 200 ml/5 l of water/100 m2 of surface.
CONTRAINDICATIONS
It should not be administered to poultry, cats, young cattle below 6 weeks of age, young sheep less
than 3 weeks of age and suckling pigs.
The animals should not be treated in wet or hot weather.
The sheep within 14 days post shearing, hypothreptic and pregnant animals, those with uncured
shearing-induced wounds and the thirsty ones should not be dipped.
PRECAUTIONS
No copper sulphate or other moisturing agents should be added to the dip.
The udder of the suckling ewes, sows and cows should be washed after dipping.
The operator should avoid inhaling the vapours when spraying.
The antidotes are atropine or toxogonine administered under the veterinarians supervision.
The product is toxic to poultry, bees and fish.
WITHDRAWAL TIME
Meat: 12 days since the last administration.
Milk: 3 days since the last administration.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 500 or 1000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

DIGESTIM
SOLUTION

COMPOSITION
Veratrum extract
15 ml
Wormwood tincture
15 ml
Juniper tincture
15 ml
Concentrated hydrochloric acid
12 ml
Hydromineral excipient up to 100 ml
PHARMACOTHERAPEUTIC ACTIVITY
The product acts on the digestive mucosa (an exciting effect), particularly
in the rumen, reticulum and omasum, leading thus to the intensification or
resuming of the gastric compartments movements. Through its action on
the digestive mucosa, it indirectly stimulates rumination and, therefore, the
digestion improvement.
INDICATIONS
Cattle, sheep, goats: Indigestions induced by the omasum overcharge,
chronic atonias of the rumen, reticulum and omasum, hyposecretory
dyspepsias.
ADMINISTRATION AND DOSAGE
Orally as follows:
Adult cattle: 25-50 ml diluted in 1 l of water, 2-3 times a day.
Calves, sheep, goats: 25 ml in 500 ml of water, 12 times a day.
CONTRAINDICATIONS
Traumatic reticulitis, peritonitis, hyperhydrochloridia.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 250 or 500 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

DIZENTER
POWDER

COMPOSITION
Lincomycin (as hydrochloride)
11 g
Spectinomycin (as sulphate)
11 g
Oxytetracycline (as hydrochloride)
300 g
Excipient
up to 1 000 g
PHARMACOTHERAPEUTIC ACTIVITY
The lincomycin-spectinomycin combination creates a broad antimicrobial
spectrum. Lincomycin is active against Gram-positive bacterial germs
such as Mycoplasma spp., and Brachyspira (Serpulina, Treponema)
hyodysenteriae. Spectinomycin acts against many Gram-negative and positive bacterial species. Oxytetracycline has a broad activity spectrum
against various Gram-positive and -negative bacteria.
INDICATIONS
Prophylaxis and treatment of dysenteriform syndromes and polymicrobial
enteropulmonary infections in suckling and young pigs during weaning.
The animals competence improvement by their health condition
maintenance.
ADMINISTRATION AND DOSAGE
Premixes are performed for the thorough product homogenisation.
Prophylaxis (sucklers, young pigs): 1 kg/t of feed (1 g/kg of feed), daily
for 3-7 days during weaning.
Treatment: 2 kg /t of feed (2 g/kg of feed), daily for 3-7 days.
With chronic cases, therapy may be extended to 2-3 weeks.
CONTRAINDICATIONS
Ruminants, horses, rabbits.
WITHDRAWAL TIME
Meat: 3 days since the last administration.
STORAGE
At 20oC, protected from humidity.
PACKAGING
Sachet of 50, 100, 200 or 500 g, or bag of 1 or 25 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMAN

ECTOCANIGAL
EXTERNAL POWDER

COMPOSITION
Azamethiphos
1%
PHARMACOTHERAPEUTIC ACTIVITY
Azamethiphos acts against ectoparasites by paralysing them and thus not
allowing them to feed.
INDICATIONS
Poultry: Control of lice (Dermanyssus, Lipeurus) and bed bugs (Cimex).
Dogs: Control of fleas (Ctenocephalus canis).
ADMINISTRATION
Hens, ducks, geese, pigeons: Powdering, mostly of heavily parasited
areas, after the feathers are grown.
Dogs: Spraying the depth of the fur (against the fur) in the areas
inaccessible to the animal (the nape, the prepectoral area).
The treatment is repeated after 10 days. The houses are powdered as
well.
PRECAUTIONS
The food and feed contamination and the powder inhaling should be
avoided.
The antidote is, in case of hypersensitive animals, atropine.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 50-100 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ECVIPAST
PASTE

COMPOSITION
Albendazole
16 g
Excipient
up to 100 g
PHARMACOTHERAPEUTIC ACTIVITY
Through albendazole, its active ingredient, the product administered
orally is readily absorbed in organs and tissues acting against adult and
larval nematodes, and adult cestodes irrespective of their localisation. It is
also active against nematodes eggs (an ovicidal effect).
INDICATIONS
Horses: Parascariosis, trichostrongylosis, strongylosis, cestodosis
(Anoplocephala).
ADMINISTRATION AND DOSAGE
The dose is 8 mg of active ingredient/kg or 5 g of ECVIPAST/100 kg of body
weight.
It is administered orally by the mouth commissure, at the tongue basis,
taking care that the mouth is free of feed remnants. The bottle content
should be homogenised before use.
CONTRAINDICATIONS
Mares during the first month of gestation.
WITHDRAWAL TIME
Meat: 10 days since the treatment.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Plastic syringe of 30 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ECVIPAST N
PASTE

COMPOSITION
Albendazole
8g
Neguvon
35 g
Excipient
up to 100 g
PHARMACOTHERAPEUTIC ACTIVITY
Through albendazole and neguvon, its active ingredients, the product
administered orally is readily absorbed being active against adult and
larval nematodes and adult cestodes irrespective of their localisation. It is
active against nematodes eggs (an ovicidal effect).
INDICATIONS
Horses infested with Gasterophilus sp., Oxyuris equi, Parascaris equorum,
Strongylus equinus, vulgaris and edentatus, Trichostrongylus axei,
Anoplocephala sp.
ADMINISTRATION AND DOSAGE
The dose is 8 mg of albendazole and 35 mg of neguvon/kg of live weight
or 10 g of ECVIPAST N/100 kg of live weight.
It is administered orally by the mouth commissure, at the tongue basis,
taking care that the mouth is free of feed remnants. The bottle content
should be homogenised before use.
CONTRAINDICATIONS
Mares during the first month of gestation.
PRECAUTIONS
In case of allergic reactions to neguvon, atropine sulphate is used as an
antidote.
WITHDRAWAL TIME
Meat: 10 days since the treatment.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Plastic syringe of 30 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

EFFERVESCENT AND FOAMING


PESSARIES WITH NEOMYCIN AND OXYTETRACYCLINE
VAGINAL TABLETS

COMPOSITION
One tablets contains:
Neomycin
0.25 g
Oxytetracycline
0.25 g
Excipient
up to 5.00 g
PHARMACOTHERAPEUTIC ACTIVITY
The association of two antibiotics, i.e. neomycin and oxytetracycline, leads to a
synergetic bacteriostatic and bactericidal action against a large group of Gramnegative (Escherichia coli, Shigella, Salmonella, Proteus) and Gram-positive
germs (Streptococcus, Staphylococcus, Clostridium, etc.) frequently involved in
the inflammatory processes of the reproductive organs. Due to the foaming and
effervescence, the active ingredients are uniformly dispersed on the uterovaginal mucosal surface, readily diffusing into tissues and humours.
INDICATIONS
Placental retentions, uterine and vaginal prolapse, dystocias attended with tissue
lesions, various uterine surgeries, cervicites, vaginites, metrites, acute and
chronic endometrites.
ADMINISTRATION AND DOSAGE
Manually, with a forceps or special devices as follows:
Large animals: 4-6 pessaries/day, for 3-4 days.
Medium sized animals: 2-3 pessaries/day, for 2-3 days.
Small animals: 1/2 pessary/day, for 2-3 days.
STORAGE
At 2-8oC, protected from light and humidity.
PACKAGING
Box of 25 or 150 pessaries.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ENERGOSOL
SOLUBLE POWDER

COMPOSITION
Sodium chloride

22.10
g
Calcium gluconate
2.10 g
Monopotassium
16.20
phosphate
g
Magnesium sulphate
0.10 g
Glycocol
34.00
g
Glutamic acid
4.20 g
Lactose
21.30
g
PHARMACOTHERAPEUTIC ACTIVITY
Due to its mineral salts components, the product ensures the intake of the
main ions and of water, replacing the losses caused by diarrhoea. The
plastic and energetic elements ensure the intake of nutrients necessary in
the diseased animal diet, and help restore the hydroelectrolytic and
metabolic balance.
INDICATIONS
Control of diarrhoea-induced dehydration of animals, particularly when the
animal is on a diet.
ADMINISTRATION AND DOSAGE
236 g are dissolved in 10 l of lukewarm water or herbal plant tea, and
orally administered by means of the feeding bottle, syringe or in the
drinking water.
Cattle:
5 l of solution in 2-3 portions/calf/day.
Swine:
5-10 ml of solution twice a day for sucklers, and 20 ml of
solution twice a day for young pigs or as directed by the veterinarian.
The solution administration is accompanied by a chemotherapeutic or by
antibiotics (depending on the case) to control the intestinal infection (once
the diarrhoea infectious aetiology is determined and the antibiogram
performed).
The ENERGOSOL-based diet lasts a few days, depending on the case,
without exceeding 5 days however.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Aluminium foil sachet of 50-1000 g, or hydrophobic paper bag/sack of 125 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ENROBACT
TABLETS
COMPOSITION
1 tablet contains:
Enrofloxacin
15 mg
PHARMACOTHERAPEUTIC ACTIVITY
Enrofloxacin is a fluoroquinolone of a wide antibacterial spectrum. It inhibits the proteinic synthesis
in the bacterial cell. It is active against the microorganisms resistant to beta lactamic antibiotics,
tetracyclines, aminoglycosides and macrolides. It is readily absorbed, the maximum plasmatic and
tissular concentration being reached 1-2 hours since the oral administration. The highest
concentrations are in the bile, liver, kidneys, lungs and the genitalia. The therapeutic levels are also
found in bones, the synovial fluid, skin, muscles, aqueous tumors and the pleural fluid. Enrofloxacin
and its active metabolites are excreted through the kidneys and the digestive tract. The half life is 4
hours, and 24 hours post the last administration no substance is traced any longer in the blood
serum or tissues. Enrofloxacin is active against Escherichia coli, Salmonella sp., Campylobacter
sp., Haemophilus sp., Pasteurella sp., Bordetella sp., Klebsiella sp., Proteus sp., Staphylococcus
aureus, Streptococcus sp., Mycoplasma sp. and against enterococci. Although the antibiotic has a
wide spectrum of action, anaerobes seem to be resistant. A long-term exposure to subtherapeutic
doses may lead to resistance phenomena.
INDICATIONS
Dogs, cats: Treatment of the bacterial infections of the intestinal, respiratory and uro-genital
apparatus, and of skin infections.
Poultry: Prophylactically and curatively in mycoplasmosis, respiratory infections, colibacillosis,
pasteurellosis, avian infectious coryza, salmonellosis and other conditions induced by
enrofloxacin-sensitive bacteria.
ADMINISTRATION AND DOSAGE
Orally, twice a day, as such or in the feed.
Dogs, cats
Enrofloxacin-sensitive germs infections: 1 tablet 6 kg of live weight (2.5 mg of enrofloxacin kg),
every 12 hours.
Urinary apparatus infections: 1-2 tablets 6 kg of live weight (2.5-5.0 mg of enrofloxacin kg),
every 12 hours.
Other systemic infections: 1 tablet 6 kg of live weight (2.5 mg of enrofloxacin kg), every 12
hours.
Pseudomonas aeruginosa infections: 3 tablets 6 kg (7.5 mg of enrofloxacin kg), every 12 hours.
The treatment lasts 5-10 days depending on the condition severity. Dehydrations will be avoided
during the treatment.
Poultry
1 tablet / 1.5 kg of live weight (10 mg of enrofloxacin / kg of live weight / day) administered as such
or mixed in the feed. Dehydrations will be avoided during the treatment.
CONTRAINDICATIONS
Small and medium-sized dogs below 8 months of age and large dogs younger than 18 months, as
it may induce changes in the articular cartilages of growing animals. Pregnant animals.
It will not be associated with antiacid drugs, aminoglycosides, cephalosporins, broad-spectrum
penicillins, nitrofuran.
WITHDRAWAL TIME
Poultry meat: 7 days since the last treatment.
STORAGE
o
At 18-25 C, protected from light.
PACKAGING
Bottle of 20 or 50 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ENROFLOXACIN 2.5%
CONCENTRATED ORAL SOLUTION

COMPOSITION
1 ml contains:
Enrofloxacin 25 mg
PHARMACOTHERAPEUTIC ACTIVITY
Enrofloxacin is a chemotherapeutic of the synthetic fluoroquinolones
group efficient against Gram-positive bacteria (Staphylococcus spp.,
Clostridium spp., Erysipelothrix rhusiopathiae, Corynebacterium spp.,
Streptococcus spp., Bacillus cereus), Gram-negative ones (Escherichia
coli, Klebsiella spp., Salmonella spp., Campylobacter spp., Pasteurella
spp., Proteus spp., Serratia spp., Yersinia spp., Pseudomonas spp.,
Bordetella spp., Moraxella bovis, Haemophilus spp., Vibrio spp.,
Actinobacillus spp., Bacteroides spp., Brucella spp.) and mycoplasmas
(Mycoplasma spp.). Enrofloxacin is active mainly against the
microorganisms that are resistant to beta lactamic antibiotics,
tetracyclines, aminoglycosides, macrolides and antagonists of the folic
acid (sulphonamides, trimethoprim). The absorption and distribution in the
tissues are rapid, after the oral administration, and the excretion is through
the kidneys and bile.
INDICATIONS
Poultry: Mycoplasmosis, bacterial diseases, chronic respiratory
infections, colibacillosis, pasteurellosis, avian infectious coryza,
salmonellosis, staphylococcias, hepatites, arthrites.
Cattle, sheep, goats, swine: Infections of the digestive and respiratory
tracts, secondary bacterial infections found in enterites and respiratory
diseases of viral aetiology.
Dogs, cats: Respiratory, digestive and uro-genital infections, dermatites.
ADMINISTRATION AND DOSAGE
Poultry: Daily, in the drinking water.
Bacteria- and mycoplasmas-induced diseases prophylaxy and treatment:
2 ml/l of drinking water for 3 days.
Salmonella infections treatment: 2ml/l of drinking water for 5 days.
Cattle, sheep, goats, swine, dogs: Daily, in the drinking water, milk or milk
replacers.
Bacteria- and mycoplasmas-induced diseases prophylaxy and treatment:
1 ml/10 kg of body weight (2.5 mg of enrofloxacin/kg of body weight) for
3 days.
Severe respiratory diseases and Salmonella infections treatment: 1 ml/5
kg of body weight for 5 days.
CONTRAINDICATIONS
Horses, young dogs up to 12 months of age, lactating or pregnant bitches,
dogs formerly diseased with epilepsy.
WITHDRAWAL TIME
Chicken meat: 7 days since the last administration.
Turkey meat: 10 days since the last administration.
Ruminant meat: 7 days since the last administration.
Pork: 5 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Polyethylene bottle of 100 or 500 ml, or can of 1 or 5 l.
MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ENROFLOXACIN 5%
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Enrofloxacin 50 mg
PHARMACOTHERAPEUTIC ACTIVITY
Enrofloxacin is a chemotherapeutic of the synthetic fluoroquinolones
group efficient against Gram-positive bacteria (Staphylococcus sp.,
Clostridium spp., Erysipelothrix rhusiopathiae, Corynebacterium spp.,
Streptococcus spp., Bacillus cereus), Gram-negative ones (Escherichia
coli, Klebsiella spp., Salmonella spp., Campylobacter spp., Pasteurella
spp., Proteus spp., Serratia spp., Yersinia spp., Pseudomonas spp.,
Bordetella spp., Moraxella bovis, Haemophilus spp., Vibrio spp.,
Actinobacillus spp., Bacteroides spp., Brucella spp.) and mycoplasmas
(Mycoplasma spp.). Enrofloxacin is active mainly against microorganisms
that are resistant to beta lactamic antibiotics, tetracyclines,
aminoglycosides, macrolides and antagonists of the folic acid
(sulphonamides, trimethoprim). The absorption and distribution in the
tissues are rapid, and the excretion is through the kidneys and bile.
INDICATIONS
Cattle, sheep, goats, swine: Infections of the digestive and respiratory
tracts, secondary bacterial infections found in enterites and respiratory
diseases of viral aetiology.
Dogs, cats: Respiratory, digestive and uro-genital infections, dermatites.
ADMINISTRATION AND DOSAGE
Cattle: 5 ml/100 kg of body weight (2.5 mg/kg of body weight) daily for 3
days by the subcutaneous route.
Sheep, goats: 1 ml/20 kg of body weight (2.5 mg/kg of body weight) daily
for 3 days by the subcutaneous route.
Swine: 1 ml/20 kg of body weight (2.5 mg/kg of body weight) daily for 3
days by the intramuscular route.
Severe respiratory infections or salmonellosis: The dose is doubled and
administered for 5 days.
Cats, dogs: 1ml/10kg of body weight (5 mg/kg of body weight) daily for 5
days by the subcutaneous route.
CONTRAINDICATIONS
Horses, young dogs up to 12 months of age, lactating or pregnant bitches,
dogs formerly diseased with epilepsy.
PRECAUTIONS
Amounts higher than 5, 2.5 and 5 ml will not be administered at one site to
cattle, pigs and sows respectively.
WITHDRAWAL TIME
Ruminant meat: 7 days since administration.
Pork: 5 days since administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Brown bottle of 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ENROFLOXACIN 5
TABLETS

COMPOSITION
1 tablet contains:
Enrofloxacin 5 mg
PHARMACOTHERAPEUTIC ACTIVITY
Enrofloxacin is a chemotherapeutic of the synthetic fluoroquinolones
group efficient against Gram-positive bacteria (Staphylococcus spp.,
Clostridium spp., Erysipelothrix rhusiopathiae, Corynebacterium spp.,
Streptococcus spp., Bacillus cereus), Gram-negative ones (Escherichia
coli, Klebsiella spp., Salmonella spp., Campylobacter spp., Pasteurella
spp., Proteus spp., Serratia spp., Yersinia spp., Pseudomonas spp.,
Bordetella spp., Moraxella bovis, Haemophilus spp., Vibrio spp.,
Actinobacillus spp., Bacteroides spp., Brucella spp.) and mycoplasmas
(Mycoplasma spp.). Enrofloxacin is active mainly against the
microorganisms that are resistant to beta lactamic antibiotics,
tetracyclines, aminoglycosides, macrolides and antagonists of the folic
acid (sulphonamides, trimethoprim). The absorption and distribution in the
tissues are rapid, after the oral administration, and the excretion is through
the kidneys and bile.
INDICATIONS
Poultry: Mycoplasmosis, bacterial diseases, chronic respiratory
infections, colibacillosis, pasteurellosis, avian infectious coryza,
salmonellosis, staphylococcias, hepatites, arthrites.
Sheep, goats, swine: Infections of the digestive and respiratory tracts,
secondary bacterial infections found in enterites and respiratory diseases
of viral aetiology.
Dogs, cats: Respiratory, digestive and uro-genital infections, dermatites.
ADMINISTRATION AND DOSAGE
In the feed, as such or broken, to poultry, pigs, dogs and cats.
The daily dose is 1 tablet/kg of body weight (5 mg/kg of body weight)
administered for 5 days.
CONTRAINDICATIONS
Horses, young dogs up to 12 months of age, lactating or pregnant bitches,
dogs formerly diseased with epilepsy.
It is antagonistic to chloramphenicol, macrolide antibiotics, tetracyclines
and nonsteroid anti-inflammatories.
WITHDRAWAL TIME
Chicken meat: 7 days since the last administration.
Turkey meat: 10 days since the last administration.
Pork: 5 days since the last administration.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Polyethylene bottle of 50 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ENROFLOXACIN 10%
CONCENTRATED ORAL SOLUTION

COMPOSITION
1 ml contains:
Enrofloxacin 100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Enrofloxacin is a chemotherapeutic of the synthetic fluoroquinolones
group efficient against Gram-positive bacteria (Staphylococcus spp.,
Clostridium spp., Erysipelothrix rhusiopathiae, Corynebacterium spp.,
Streptococcus spp., Bacillus cereus), Gram-negative ones (Escherichia
coli, Klebsiella spp., Salmonella spp., Campylobacter spp., Pasteurella
spp., Proteus spp., Serratia spp., Yersinia spp., Pseudomonas spp.,
Bordetella spp., Moraxella bovis, Haemophilus spp., Vibrio spp.,
Actinobacillus spp., Bacteroides spp., Brucella spp.) and mycoplasmas
(Mycoplasma spp.). Enrofloxacin is active mainly against the
microorganisms that are resistant to beta lactamic antibiotics,
tetracyclines, aminoglycosides, macrolides and antagonists of the folic
acid (sulphonamides, trimethoprim). The absorption and distribution in the
tissues are rapid, after the oral administration, and the excretion is through
the kidneys and bile.
INDICATIONS
Poultry: Mycoplasmosis, bacterial diseases, chronic respiratory
infections, colibacillosis, pasteurellosis, avian infectious coryza,
salmonellosis, staphylococcias, hepatites, arthrites.
Cattle, sheep, goats, swine: Infections of the digestive and respiratory
tracts, secondary bacterial infections found in enterites and respiratory
diseases of viral aetiology.
Dogs, cats: Respiratory, digestive and uro-genital infections, dermatites.
ADMINISTRATION AND DOSAGE
Poultry: Daily, in the drinking water.
Bacteria- and mycoplasmas-induced diseases prophylaxy and treatment: 2
ml/l of drinking water for 3 days.
Salmonella infections treatment: 2ml/l of drinking water for 5 days.
Cattle, sheep, goats, swine, dogs: Daily, in the drinking water, milk or milk
replacers.
Bacteria- and mycoplasmas-induced diseases prophylaxy and treatment: 1
ml/20 kg of body weight (5 mg of enrofloxacin/kg of body weight) on day 1,
and half this dose during the following 4 days.
CONTRAINDICATIONS
Horses, young dogs up to 12 months of age, lactating or pregnant bitches,
dogs formerly diseased with epilepsy.
WITHDRAWAL TIME
Chicken meat: 7 days since the last administration.
Turkey meat: 10 days since the last administration.
Ruminant meat: 7 days since the last administration.
Pork: 5 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Polyethylene bottle of 100 or 500 ml, or can of 1 or 5 l.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ENROFLOXACIN 10%
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Enrofloxacin 100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Enrofloxacin is a chemotherapeutic of the synthetic fluoroquinolones
group efficient against Gram-positive bacteria (Staphylococcus spp.,
Clostridium spp., Erysipelothrix rhusiopathiae, Corynebacterium spp.,
Streptococcus spp., Bacillus cereus), Gram-negative ones (Escherichia
coli, Klebsiella spp., Salmonella spp., Campylobacter spp., Pasteurella
spp., Proteus spp., Serratia spp., Yersinia spp., Pseudomonas spp.,
Bordetella spp., Moraxella bovis, Haemophilus spp., Vibrio spp.,
Actinobacillus spp., Bacteroides spp., Brucella spp.) and mycoplasmas
(Mycoplasma spp.). Enrofloxacin is active mainly against the
microorganisms that are resistant to beta lactamic antibiotics,
tetracyclines, aminoglycosides, macrolides and antagonists of the folic
acid (sulphonamides, trimethoprim). The absorption and distribution in the
tissues are rapid, and the excretion is through the kidneys and bile.
INDICATIONS
Cattle, sheep, goats, swine: Infections of the digestive and respiratory
tracts, secondary bacterial infections found in enterites and respiratory
diseases of viral aetiology.
Dogs, cats: Respiratory, digestive and uro-genital infections, dermatites.
ADMINISTRATION AND DOSAGE
Cattle: 2.5 ml/100 kg of body weight (2.5 mg/kg of body weight) daily for
3 days by the subcutaneous route.
Sheep, goats: 2.5 ml/100 kg of body weight (2.5 mg/kg of body weight)
daily for 3 days by the subcutaneous route.
Swine: 2.5 ml/100 kg of body weight (2.5 mg/kg of body weight) daily for
3 days by the intramuscular route.
Severe respiratory infections or salmonellosis: The dose is doubled and
administered for 5 days.
Cats, dogs: 1ml/20kg of body weight (5 mg/kg of body weight) daily for 5
days by the subcutaneous route.
CONTRAINDICATIONS
Horses, young dogs up to 12 months of age, lactating or pregnant bitches,
dogs formerly diseased with epilepsy.
PRECAUTIONS
Amounts higher than 5, 2.5 and 5 ml will not be administered at one site to
cattle, pigs and sows respectively.
WITHDRAWAL TIME
Ruminant meat: 7 days since administration.
Pork: 5 days since administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Brown bottle of 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ENROFLOXACIN 25
TABLETS

COMPOSITION
1 tablet contains:
Enrofloxacin 25 mg
PHARMACOTHERAPEUTIC ACTIVITY
Enrofloxacin is a chemotherapeutic of the synthetic fluoroquinolones
group efficient against Gram-positive bacteria (Staphylococcus spp.,
Clostridium spp., Erysipelothrix rhusiopathiae, Corynebacterium spp.,
Streptococcus spp., Bacillus cereus), Gram-negative ones (Escherichia
coli, Klebsiella spp., Salmonella spp., Campylobacter spp., Pasteurella
spp., Proteus spp., Serratia spp., Yersinia spp., Pseudomonas spp.,
Bordetella spp., Moraxella bovis, Haemophilus spp., Vibrio spp.,
Actinobacillus spp., Bacteroides spp., Brucella spp.) and mycoplasmas
(Mycoplasma spp.). Enrofloxacin is active mainly against the
microorganisms that are resistant to beta lactamic antibiotics,
tetracyclines, aminoglycosides, macrolides and antagonists of the folic
acid (sulphonamides, trimethoprim). The absorption and distribution in the
tissues are rapid, after the oral administration, and the excretion is through
the kidneys and bile.
INDICATIONS
Poultry: Mycoplasmosis, bacterial diseases, chronic respiratory
infections, colibacillosis, pasteurellosis, avian infectious coryza,
salmonellosis, staphylococcias, hepatites, arthrites.
Sheep, goats, swine: Infections of the digestive and respiratory tracts,
secondary bacterial infections found in enterites and respiratory diseases
of viral aetiology.
Dogs, cats: Respiratory, digestive and uro-genital infections, dermatites.
ADMINISTRATION AND DOSAGE
In the feed, as such or broken, to poultry, pigs, dogs and cats.
The daily dose is 1 tablet/5 kg of body weight (5 mg/kg of body weight)
administered for 5 days.
CONTRAINDICATIONS
Horses, young dogs up to 12 months of age, lactating or pregnant bitches,
dogs formerly diseased with epilepsy.
It is antagonistic to chloramphenicol, macrolide antibiotics, tetracyclines
and nonsteroid anti-inflammatories.
WITHDRAWAL TIME
Chicken meat: 7 days since the last administration.
Turkey meat: 10 days since the last administration.
Pork: 5 days since the last administration.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Polyethylene bottle of 50 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ENROFLOXACIN 50
TABLETS

COMPOSITION
1 tablet contains:
Enrofloxacin 50 mg
PHARMACOTHERAPEUTIC ACTIVITY
Enrofloxacin is a chemotherapeutic of the synthetic fluoroquinolones
group efficient against Gram-positive bacteria (Staphylococcus spp.,
Clostridium spp., Erysipelothrix rhusiopathiae, Corynebacterium spp.,
Streptococcus spp., Bacillus cereus), Gram-negative ones (Escherichia
coli, Klebsiella spp., Salmonella spp., Campylobacter spp., Pasteurella
spp., Proteus spp., Serratia spp., Yersinia spp., Pseudomonas spp.,
Bordetella spp., Moraxella bovis, Haemophilus spp., Vibrio spp.,
Actinobacillus spp., Bacteroides spp., Brucella spp.) and mycoplasmas
(Mycoplasma spp.). Enrofloxacin is active mainly against the
microorganisms that are resistant to beta lactamic antibiotics,
tetracyclines, aminoglycosides, macrolides and antagonists of the folic
acid (sulphonamides, trimethoprim). The absorption and distribution in the
tissues are rapid, after the oral administration, and the excretion is through
the kidneys and bile.
INDICATIONS
Poultry: Mycoplasmosis, bacterial diseases, chronic respiratory
infections, colibacillosis, pasteurellosis, avian infectious coryza,
salmonellosis, staphylococcias, hepatites, arthrites.
Sheep, goats, swine: Infections of the digestive and respiratory tracts,
secondary bacterial infections found in enterites and respiratory diseases
of viral aetiology.
Dogs, cats: Respiratory, digestive and uro-genital infections, dermatites.
ADMINISTRATION AND DOSAGE
In the feed, as such or broken, to poultry, pigs, dogs and cats.
The daily dose is 1 tablet/10 kg of body weight (5 mg/kg of body weight)
administered for 5 days.
CONTRAINDICATIONS
Horses, young dogs up to 12 months of age, lactating or pregnant bitches,
dogs formerly diseased with epilepsy.
It is antagonistic to chloramphenicol, macrolide antibiotics, tetracyclines
and nonsteroid anti-inflammatories.
WITHDRAWAL TIME
Pork: 5 days since the last administration.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Polyethylene bottle of 30 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

EQVAMEC P
ANTIPARASITIC PASTE

COMPOSITION
1 ml contains:
Ivermectin 20 mg
PHARMACOTHERAPEUTIC ACTIVITY
Ivermectin is active against endo- and ectoparasites of horses. It
stimulates, in nematodes, the gamma aminobutyric acid (GABA)
production, thus interrupting the nervous influx transmission to the
nervous junctions, paralysing and killing the parasite. In arthropods,
ivermectin interrupts the nervous influx in the neuromuscular synapse
inducing the parasites paralysis and death.
INDICATIONS
Prophylaxis and treatment of the following parasitoses induced by:
Nematodes: Gastrointestinal (Strongylus vulgaris, Strongylus edentatus,
Strongylus equinus, Strongylus bidentatus, Triodontophorus spp.,
Oxyuris equi, Cyathostomum spp.), peritoneal (Setaria equina), ocular
and cutaneous (Habronema spp.), bronchopulmonary (Dictyocaulus
arnfieldi), cervical and tendinous ones (Onchocerca cervicalis,
Onchocerca reticulata ).
Larval insects: Rhinoestrus purpureus, Gasterophilus spp.
ADMINISTRATION AND DOSAGE
1 ml of paste/100 kg of body weight (20 mg of ivermectin/100 kg of body
weight) is administered per os.
The syringe is as deeply as possible introduced into the horses interdental
space of the buccal cavity, placing the drug at the tongue basis. The
animals head is lifted for a few seconds immediately post administration.
Foals may be treated starting with 6-8 weeks of age.
SIDE EFFECTS
The recommended doses have a very wide margin of protection for
animals.
No side effects have been noticed in pregnant mares, studs or young
horses.
PRECAUTIONS
Before the paste administration, care should be taken for the buccal cavity
to be free from any feeds.
It should not be administered to other species.
The hands should be washed immediately after handling the paste.
There should be no eating or smoking during the paste handling.
The eye contact should be avoided.
It should be kept out of the reach of children.
WITHDRAWAL TIME
Meat: 14 days since the last treatment.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic syringe of 6 ml.
MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

EVOMEC
INJECTABLE SOLUTION

COMPOSITION
Ivermectin 1%
PHARMACOTHERAPEUTIC ACTIVITY
Ivermectin acts against the endo- and ectoparasites of cattle, sheep and
swine.
INDICATIONS
Cattle: Gastrointestinal (larvae and adults) and pulmonary nematodes,
agents inducing myases and scabies, malophagus lice, mites.
Sheep: Gastrointestinal and pulmonary nematodes, agents inducing
scabies.
Pigs: Gastrointestinal, pulmonary and renal nematodes, lice, scabies
inducing agents.
ADMINISTRATION AND DOSAGE
Strictly subcutaneously at various animal species- and weight-dependent
doses:
Cattle:
1 ml (10 mg of ivermectin)/50 kg of live weight.
Sheep: 0.5 ml/25 kg of live weight.
Pigs: 1ml/33 kg of live weight.
The treatment programme recommended for swine:
Breeders (the treatment frequency depends on the exposure to the
infestation):
Sows: 7-14 days before farrowing.
Gilts: 7-14 days before both service and farrowing.
Boars: Twice a year.
Fatteners: The pigs being transferred to fattening units should be
treated before being introduced into clean boxes.
CONTRAINDICATIONS
It should not be inoculated intramuscularly or intravenously.
PRECAUTIONS
In a parasites control programme, it is important that all the animals be
treated.
It should be kept out of the reach of children.
WITHDRAWAL TIME
Meat: 28 days since the last treatment.
Milk: 28 days since the last treatment.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 10, 20, 50, 100 or 500 ml.
MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

FENAZON
TABLETS

COMPOSITION
1 tablet contains:
Dexamethasone
0.2 mg
Pheniramine (as maleate)
14 mg
Biotin
0.25 mg
Methionine
0.4 mg
PHARMACOTHERAPEUTIC ACTIVITY
Dexamethasone is a potent anti-inflammatory of prolonged action (36-72
hours), while pheniramine is an antihistaminic efficient in preventing and
treating allergies of various aetiologies. Biotin (vitamin H) and methionine
have a trophic action on the epidermis and pilous follicles facilitating their
integrity restoration.
INDICATIONS
Dogs, cats: Allergic dermatites of various aetiologies (feed, contact
ectoparasites).
Adjuvant in the treatment of external otites due to its anti-inflammatory and
antihistaminic components.
ADMINISTRATION AND DOSAGE
Orally, as such or mixed in the feed: 1 tablet/8-10 kg of body weight/day
for 3-8 days.
CONTRAINDICATIONS
Diabetes mellitus, osteoporosis, gestation, glaucoma, very old animals,
kidney and heart diseases, obstruction of the bile ducts.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Bottle of 20 or 50 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

FTALIPEPS 50 mg
TABLETS

COMPOSITION
1 tablet contains:
Phthalylsulfathiazole
50 mg
Pepsin
10 mg
PHARMACOTHERAPEUTIC ACTIVITY
Phthalylsulfathiazole is a sulphonamide active against the bacteria in the
digestive tract colibacilli in particular susceptible to induce
gastroenterites. Its absorption is reduced; however, it releases through
hydrolysis sulfathiazole that plays a role in the control of the infections
localised in the digestive tract. Pepsin is a proteolytic enzyme commonly
found in the stomach. The product permits the deficiency of pepsin
endogenous secretion to be compensated, and facilitates the normal
gastric digestion.
INDICATIONS
Dogs, cats: Treatment of gastroenterites.
Dogs: Ulcerative colites.
ADMINISTRATION AND DOSAGE
The tablets are administered as such or triturated and mixed in the feed.
Dose: 1 tablet/5 kg of live weight, twice a day, for 3-5 days depending on
the disease course.
CONTRAINDICATIONS
Kidney or liver insufficiency, sensitivity to sulphonamides.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Bottle of 25 or 50 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

FTALIPEPS

250 mg
TABLETS

COMPOSITION
1 tablet contains:
Phthalylsulfathiazole
250 mg
Pepsin
100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Phthalylsulfathiazole is a sulphonamide active against the bacteria in the
digestive tract colibacilli in particular susceptible to induce
gastroenterites. Its absorption is reduced; however, it releases through
hydrolysis sulfathiazole that plays a role in the control of the infections
localised in the digestive tract. Pepsin is a proteolytic enzyme commonly
found in the stomach. The product permits the deficiency of pepsin
endogenous secretion to be compensated, and facilitates the normal
gastric digestion.
INDICATIONS
Treatment of gastroenterites of all species irrespective of age. Also,
preventively in clinically healthy animals in populations where digestive
conditions are present.
ADMINISTRATION AND DOSAGE
The tablets are administered as such or triturated and mixed in water, tea,
milk or grists. Preferably, the treatment should be individual.
Dose: 1 tablet/5 kg of live weight, twice a day for 3-5 days depending on
the disease course.
CONTRAINDICATIONS
Kidney or liver insufficiency, sensitivity to sulphonamides.
WITHDRAWAL TIME
Meat, organs: 14 days since the last administration.
Milk: 4 days since the last administration.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Bottle of 25 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GENTAMYCIN 5%
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Gentamycin sulphate
50 mg
PHARMACOTHERAPEUTIC ACTIVITY
Gentamycin is a bactericidal antibiotic of the aminoglycosides group being
active both in the germs multiplication and non multiplication phases. Its
activity spectrum is relatively wide including Gram-positive and -negative
germs [Enterobacter aerogenes, Escherichia coli, Pasteurella spp.,
Pseudomonas aeruginosa, Serratia spp., Campylobacter coli, Brachyspira
(Serpulina, Treponema) hyodysenteriae], and mycoplasmas (Mycoplasma
spp.).
INDICATIONS
Cattle, horses, sheep, goats, swine, dogs, cats, poultry: Prophylaxy and
treatment of respiratory, gastrointestinal and uro-genital infections,
septicaemias, arthrites, pyoarthrites, meningites, metrites, mastites and
dermatites.
ADMINISTRATION AND DOSAGE
Horses, cows: 8ml/100 kg of live weight, intramuscularly.
Calves, donkeys, swine: 4.0 ml/50 kg of live weight, intramuscularly.
Dogs, cats, piglets: 0.4ml/5 kg of live weight, intramuscularly,
subcutaneously or intravenously.
Poultry: 0.04 ml/kg of live weight, subcutaneously.
0.1 ml/kg of live weight, orally.
The administration is 12 hours apart for 3-5 days.
CONTRAINDICATIONS
Animals with renal diseases or intolerance to antibiotics, pregnant
females.
Concomitantly with other aminoglycoside antibiotics, anaesthetics or
myorelaxants.
The chloramphenicol-associated administration, and the administration of
gentamycin with other antibiotics such as ampicillin, carbenicillin,
cephalosporins, erythromycin, or with sulphonamides, the vitamin B
complex or heparin in the same syringe should be avoided.
WITHDRAWAL TIME
Meat: 7 days since the last administration.
Milk: 3 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 20, 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GENTAMYCIN 10 %
HYDROSOLUBLE POWDER

COMPOSITION
1 g contains:
Gentamycin (as sulphate)
100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Gentamycin is a bactericidal antibiotic of the aminoglycosides group being
active both in the germs multiplication and non multiplication phases.
Upon its oral administration, the resorption in the digestive tract is
nonsignificant and the excretion is active and mainly via the kidneys. Its
activity spectrum is relatively wide including Gram-positive and -negative
germs [Enterobacter aerogenes, Escherichia coli, Pasteurella spp.,
Pseudomonas aeruginosa, Serratia spp., Campylobacter coli, Brachyspira
(Serpulina, Treponema) hyodysenteriae], and mycoplasmas (Mycoplasma
spp.).
INDICATIONS
Prophylaxis and treatment of the digestive tract bacterial infections
(gastrites, enterites, dysenteries, enterocolites of piglets and calves)
induced by gentamycin sensitive germs.
ADMINISTRATION AND DOSAGE
Swine: 5 g/10 l of drinking water/day (5 g/100 kg of body weight/day).
For a constant therapeutic level, the daily dose is divided into two and
administered 12 hours apart or ad libitum. In dysentery, 11-22 g will be
dissolved in 100 l of drinking water and administered as abovementioned. Should the water consumption be higher on account of
microclimatic conditions, the dose will be adequately adapted. The
treatment lasts 3-5 days.
Young cattle: 5 g/100 kg of body weight administered twice on day I and
4g/100 kg of body weight administered once a day during the following
days. The treatment lasts 3-5 days.
Poultry: 5 g/100 l of drinking water for 5-7 days, administered ad libitum.
CONTRAINDICATIONS
Gentamycin-hypersensitive animals.
Concomitantly with chloramphenicol.
WITHDRAWAL TIME
Meat: 14 days since the last administration.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Polyethylene sachet of 50, 100 or 1000 g, or paper sack of 20 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GENTAMYCIN 10%
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Gentamycin (as sulphate)
100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Gentamycin is a bactericidal antibiotic of the aminoglycosides group being
active both in the germs multiplication and non multiplication phases. Its
activity spectrum is relatively wide including Gram-positive and -negative
germs [Enterobacter aerogenes, Escherichia coli, Pasteurella spp.,
Pseudomonas aeruginosa, Serratia spp., Campylobacter coli, Brachyspira
(Serpulina, Treponema) hyodysenteriae], and mycoplasmas (Mycoplasma
spp.).
INDICATIONS
Cattle, horses, sheep, goats, swine, dogs, cats, poultry: Prophylaxy and
treatment of respiratory, gastrointestinal and uro-genital infections,
septicaemias, arthrites, pyoarthrites, meningites, metrites, mastites and
dermatites.
ADMINISTRATION AND DOSAGE
Horses, cows: 4ml/100 kg of live weight, intramuscularly.
Calves, donkeys, swine: 2 ml/50 kg of live weight, intramuscularly.
Dogs, cats, piglets: 0.2ml/5 kg of live weight, intramuscularly,
subcutaneously or intravenously.
Poultry: 0.02 ml/kg of live weight, subcutaneously.
0.1 ml/ 50 kg of live weight, orally.
CONTRAINDICATIONS
Animals with renal diseases or intolerance to antibiotics, pregnant
females.
Concomitantly with other aminoglycoside antibiotics, anaesthetics or
myorelaxants.
The chloramphenicol-associated administration, and the administration of
gentamycin with other antibiotics such as ampicillin, carbenicillin,
cephalosporins, erythromycin, or with sulphonamides, the vitamin B
complex, heparin in the same syringe should be avoided.
WITHDRAWAL TIME
Meat: 7 days since the last administration.
Milk: 3 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 20, 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GENTOCIN DOSER
ORAL SOLUTION

COMPOSITION
1 ml contains:
Gentamycin (as sulphate)
5 mg
PHARMACOTHERAPEUTIC ACTIVITY
Gentamycin is a bactericidal antibiotic of the aminoglycosides group being
active both in the germs multiplication and non multiplication phases.
Upon its oral administration, the resorption in the digestive tract is
nonsignificant and the excretion is active and mainly via the kidneys. Its
activity spectrum is relatively wide including Gram-positive and -negative
germs [Enterobacter aerogenes, Escherichia coli, Pasteurella spp.,
Pseudomonas aeruginosa, Serratia spp., Campylobacter coli, Brachyspira
(Serpulina, Treponema) hyodysenteriae], and mycoplasmas (Mycoplasma
spp.).
INDICATIONS
Piglets (the first days of life): Prophylaxis and treatment of gastroenterites
induced by Escherichia coli and other bacteria sensitive to gentamycin.
ADMINISTRATION AND DOSAGE
1 ml (5 mg of gentamycin) is orally and daily administered with the pump
spray or a graduated syringe.
Should the symptoms not disappear after the first day, the administration
will be repeated the next day.
CONTRAINDICATIONS
Piglets older than a few days.
PRECAUTIONS
It should not be kept within the reach of children.
WITHDRAWAL TIME
Meat: 14 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GENTOCIN OPHTHALMIC
OPHTHALMIC SOLUTION

COMPOSITION
1 ml contains:
Gentamycin (as sulphate)
3 mg
PHARMACOTHERAPEUTIC ACTIVITY
Gentamycin is a bactericidal antibiotic of the aminoglycosides group being
active both in the germs multiplication and non multiplication phases. Its
spectrum is relatively large, including the Gram-positive and -negative
germs. It is very efficacious against the primary and secondary ocular
infections, particularly against those induced by betalactamic antibioticsresistant bacteria.
INDICATIONS
Treatment of ocular infections such as conjunctivites, keratites,
keratoconjunctivites,
corneal
ulcers,
blepharites
and
blepharoconjunctivites. Prophylaxis of traumata and ophthalmic surgery.
ADMINISTRATION AND DOSAGE
1-2 drops are applied into the conjunctival sac 4 hours apart (or, 1-2 hours
in severe infections).
The treatment will not exceed 7-10 days.
CONTRAINDICATIONS
Gentamycin- or other aminoglycoside antibiotics-allergic animals.
SIDE EFFECTS
The long term treatment may favour fungal superinfections.
Occasionally, it may induce local irritations or allergic reactions.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 7.5 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GENTOCIN OTIC
OTIC SOLUTION

COMPOSITION
Gentamycin (as sulphate)
0.3 g
Dexamethasone
0.1 g
PHARMACOTHERAPEUTIC ACTIVITY
Gentamycin, an aminoglycoside antibiotic, is active against Gram-positive
(staphylococci, streptococci, pneumococci) and Gram-negative germs
(colibacilli, Proteus, pyocyanic bacillus, salmonellas). Dexamethasone, a
potent gluco-corticoid, confers the product anti-inflammatory and
antiallergic properties.
INDICATIONS
Dogs, cats: Polymicrobial external otitis resistant to the treatment with
other antibiotics.
ADMINISTRATION
The ear is cleaned with OTTO-CLEANS, a cerumenolytic solution, and then
instilled with GENTOCIN OTIC into the external auditory meatus. The ear
basis is then slightly massaged for a good drug diffusion into the auditory
meatus.
2-4 drops are administered every 4 hours.
With severe infections, the same dose is administered every hour.
CONTRAINDICATIONS
Animals hyperallergic to one of the product components.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Dropper bottle of 7.5 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GERMOSTOP ANTIMASTITIS
ANTIMICROBIAL SOLUTION

COMPOSITION
Chlorhexidine digluconate
5g
Glycerine
40 ml
Excipient
up to 100 ml
PHARMACOTHERAPEUTIC ACTIVITY
Chlorhexidine digluconate is a bisbiguanide derivative of a broad
antibacterial spectrum including Gram-positive (Staphylococcus aureus,
Streptococcus spp.) and Gram-negative germs (Escherichia coli,
Pseudomonas aeruginosa, etc.). The germ colonisation in the milk pellicle
remaining at the galactophorus duct entry is mainly prevented. The
product is well tolerated.
INDICATIONS
Prophylaxis of cow mastitis.
ADMINISTRATION
The udder and the mamillae are washed with a solution of 1 part of the
product in 9 parts of potable water prepared upon the administration.
At least 3 cm of the length of each mamilla are immersed into the solution.
The treatment will be applied immediately after each milking.
During the dry period, the mamillae will be immersed into the solution
once a day for 3-4 more days.
For the preparation of a solution amount for one week, distilled or
deionised water is recommended.
PRECAUTIONS
The solution should not be used undiluted.
The contact with the eyes and conjunctival mucosa should be avoided.
The product ingestion and food contamination should be avoided.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 200, 1000 or 5000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GERMOSTOP BUCCAL
ANTISEPTIC AND DEODORISING SOLUTION

COMPOSITION
Chlorhexidine digluconate
0.1 %
PHARMACOTHERAPEUTIC ACTIVITY
Chlorhexidine digluconate is a bisbiguanide derivative having a wide
antibacterial spectrum including Gram-positive and -negative germs
(Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus). It
also decontaminates the gingivae and buccal mucosa by diminishing the
live microorganisms counts. The tensio-active substances and glycerine
do not irritate the buccal mucosa and gingivae, while the mint oil confers a
fresh pleasant odour.
INDICATIONS
Dogs, cats: Buccal hygiene, gingival conditions, prevention of the dental
plaque, mouth health maintenance by feed residues elimination, a
pleasant mouth odour.
USES
It may be applied by rinsing or brushing.
A small amount is sprayed into the space between the gingivae and teeth,
and the lips are massaged by pressing them against the teeth for the
product to be displayed all over the teeth surface.
The teeth are gently brushed with a tooth brush, with rewetting whenever
necessary for a thorough cleaning.
PRECAUTIONS
The contact with the eyes and conjunctival mucosa should be avoided.
The long-term use of chlorhexidine products may stain the teeth. The
solution application with a tooth brush may prevent it.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic sprayer bottle of 200 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GERMOSTOP DERMATOLOGICAL
ANTIMICROBIAL EMULSION OINTMENT

COMPOSITION
Chlorhexidine digluconate
1%
PHARMACOTHERAPEUTIC ACTIVITY
Chlorhexidine digluconate is a bisbiguanide derivative of a wide
antibacterial spectrum that includes numerous species of Gram-positive
and -negative germs, fungi and viruses. It acts quickly and has
antimicrobial properties without inducing side effects such as the tissular
retention. It has a long-acting effect, and ensures the treated wound
antimicrobial protection.
INDICATIONS
Dogs, cats, horses: Treatment of superficial wounds.
USES
The area of interest is cleaned, the bottle is shaken and then the wound
surface is entirely and daily applied with the product until recovery.
CONTRAINDICATIONS
Deep wounds.
PRECAUTIONS
The bottle should be agitated before use.
The contact with the eyes and conjunctival mucosa should be avoided.
It should be kept out of the reach of children.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic dropper bottle of 30 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GERMOSTOP FOR MEDICAL INSTRUMENTS


CONCENTRATED SOLUTION

COMPOSITION
Chlorhexidine digluconate
10 %
PHARMACOTHERAPEUTIC ACTIVITY
Chlorhexidine digluconate is antibacterial against Gram-positive (Bacillus
spp., Clostridium spp., Micrococcus spp., Staphylococcus spp.,
Streptococcus spp.), and Gram-negative germs (Aeromonas aerogenes,
Enterobacter cloacae, Escherichia coli, Klebsiella spp., Pseudomonas
spp., Salmonella spp., Proteus spp.) and fungi (Aspergillus spp.,
Microsporum spp., Candida spp.). The 0.05-0.1% chlorhexidine
digluconate concentration has a virucidal effect on the viruses tested: DNA
viruses with a pericapside (bovine alphaherpesvirus) and without one
(type 3 Mastadenovirus), RNA viruses with a pericapside (type 3
Paramyxovirus and Coronavirus) and without one (the infectious bursal
disease virus).
INDICATIONS
Whenever the short-term (10-15 minutes) cold sterilisation of medical
instruments of various materials (rubber, plastic, metal) is needed.
USES
The well washed instruments are 15 minutes immersed into the 0.5%
solution obtained by diluting 1 part of the concentrated solution in 19 parts
of water.
In case the instruments were not well washed or in emergencies, the
instruments are immersed for minimum 10 minutes in the 1% solution
obtained by diluting 1 part of the concentrated solution in 9 parts of water.
The instruments need not be rinsed after sterilisation as the sterilisation
solution possibly remaining on them does not negatively influence the
wounds course and does not harm the surgeons hands.
PRECAUTIONS
The contact with the eyes and conjunctival mucosa should be avoided.
Should an accidental contact occur, a water flush will be used for rinsing.
It should be kept out of the reach of children.
REMARKS
It does not attack suture materials and it is not corrosive for metals.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 200, 1000 or 5000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GERMOSTOP FOR THE UDDER


CONCENTRATED DISINFECTING SOLUTION

COMPOSITION
Chlorhexidine digluconate
4%
PHARMACOTHERAPEUTIC ACTIVITY
The product combines the wash action of the tensio-active substances
with the complex antimicrobial effect of chlorhexidine digluconate,
ensuring a clean sterile udder and mamillae surface before milking. The
consistent disinfection application leads to the mammary gland
decontamination, to the milk microbial burden reduction.
INDICATIONS
Prevention of the mammary gland infection and milk contamination.
USES
A fresh dilute solution will be prepared before each milking by introducing
30 ml (cca 2 spoonfuls) of the concentrated solution into 5 l of water.
A clean paper napkin is wetted with the dilute solution and then used to
wash the udder and mamillae, that are afterwards wiped with a clean dry
paper napkin and coupled to the milking device.
The udder and mamillae should be washed before each milking.
PRECAUTIONS
The solution will not be used undiluted.
The solution will not be used to wash the milking equipment.
The contact with the eyes and conjunctival mucosa should be avoided.
It should be kept out of the reach of children.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 200, 1000 or 5000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GERMOSTOP HEXASOL SCRUB


ANTISEPTIC LIQUID SCRUB

COMPOSITION
Chlorhexidine digluconate
2%
PHARMACOTHERAPEUTIC ACTIVITY
Chlorhexidine gluconate is a bisbiguanide derivative having a wide
antibacterial spectrum that includes many species of Gram-positive and negative bacteria, and fungi. Due to its tensio-active and protective
components, the product is not irritant, and it does not change the
suppleness, elasticity, turgor and colour of the skin, or the tactile
sensitivity.
INDICATIONS
Pre- and post-operative asepsia and antisepsia of the hands, surgical
area, superficial wounds on a restricted surface. Whenever a cleansing
with antimicrobial effect is necessary. Routine hygienisation and
decontamination.
USES
Pre-operative hands washing: 5 ml for cca 3 minutes, followed by
another 5 ml for another 3 minutes. Finally, the hands are rinsed in water
and dried.
Pre-operative surgical area washing: 1-5 ml are applied with the sponge
until a rich foaming is obtained. The foam is allowed to act for 3-5
minutes, then the excess foam is wiped off and the procedure is
repeated. Finally, water is used to rinse.
Wounds cleaning and antisepsia: 1-2 ml are applied, followed by rinsing.
Medical staffs current hands scrubbing: Cca 5 ml for cca 15 seconds,
followed by water rinsing, and drying.
PRECAUTIONS
It is only for external use.
The contact with the eyes and conjunctival mucosa should be avoided.
It should be kept out of the reach of children.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 200, 1000 or 5000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GERMOSTOP HEXASOL SURGICAL


ANTISEPTIC SOLUTION

COMPOSITION
Chlorhexidine digluconate
2%
PHARMACOTHERAPEUTIC ACTIVITY
Chlorhexidine digluconate is a bisbiguanide derivative having a broad
antimicrobial spectrum that includes many sporulated and nonsporulated
Gram-positive and -negative germs, fungi and viruses. The product
destroys bacteria, fungi and viruses in 15 minutes.
INDICATIONS
Whenever an aseptic area (surgeons hands, operating area) is
necessary; wounds asepsia and antisepsia.
The suture threads treated with the product meet the safety parameters
for mechanical characteristics (the resistance to traction, the elongation
degree during an effort, the knot safety).
USES
Surgeons hands: The hands and forearms are washed with a common
soap or with GERMOSTOP HEXASOL SCRUB, thoroughly rinsed in water, and
wiped; the hands are then wetted with a sufficient amount of the solution
for a thin film all over the surface. The solution will not be wiped off
before putting the gloves on.
Surgical area: The area of interest is covered with a sufficient solution
amount. The excess is wiped off with sterile gauze.
PRECAUTIONS
It is only for external use.
The contact with the eyes and conjunctival mucosa should be avoided.
It should be kept out of the reach of children.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 200, 1000 or 5000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GERMOSTOP L
DISINFECTING SOLUTION

COMPOSITION
Chlorhexidine digluconate
20 %
PHARMACOTHERAPEUTIC ACTIVITY
Chlorhexidine digluconate has a wide antimicrobial spectrum against
many species of Gram-positive germs (Bacillus spp., Clostridium spp.,
Staphylococcus spp., Streptococcus spp.), Gram-negative ones
(Escherichia coli, Klebsiella spp., Pseudomonas spp., Salmonella spp.,
Proteus spp.), fungi (Aspergillus spp., Candida spp.) and viruses (bovine
-herpesvirus, Mastadenovirus, Paramyxovirus, Coronavirus, infectious
bursal disease virus, etc.). It has a markedly long-lasting activity, without
inducing residual effects such as the tissular retention. It does not induce
local irritations or allergic sensitisation.
INDICATIONS
Disinfection of surfaces, installations and equipment used in the food
industry.
Disinfection of the eggs for hatching and of incubators.
Disinfection of the drinking water and drinkers.
Decontamination of the animals skin for blood sampling, products
inoculation, etc.
Syringes decontaminaton in the field.
USES
Food industry disinfection: 1 l/300-1000 l of water.
Eggs disinfection: Spraying of 1 l/150 l of water at 45oC, or eggs
immersion into 1l/150 l of water for 30-60 seconds.
Animal houses and equipment disinfection: 1 part of the product in 39
parts of potable water.
Drinking water prophylactic disinfection: 1 l/1000 l of water.
Drinkers and water supplying devices disinfection: 1l/200 l of water.
Animal skin decontamination: Painting with a cotton wool pad soaked in
the product diluted 1:10 (i.e. 2% active ingredient) in water.
Syringes, needles, mammary probes, trocars, etc. decontamination:
They are 10 minutes immersed in a 1% chlorhexidine digluconate
solution obtained by diluting 1 part of the product in 19 parts of water.
The syringes need not be rinsed after decontamination as the
chlorhexidine digluconate traces do not impair the antimicrobial effect of
antibiotics and chemotherapeutics.
PRECAUTIONS
It is not recommended for the disinfection of syringes used in vaccination
campaigns where live vaccines are used.
After preparation, the dilute solution will be used within 72 hours at the
most.
The contact with the eyes and conjunctival mucosa should be avoided. In
case of accidental contact, a water flush will be used for rinsing.
It should be kept out of the reach of children.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 200, 1000 or 5000 ml.
MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GERMOSTOP P
BIOSTIMULATING PREMIX

COMPOSITION
Chlorhexidine dihydrochloride
0.5%
PHARMACOTHERAPEUTIC ACTIVITY
Chlorhexidine dihydrochloride has a wide antimicrobial spectrum including
numerous species of Gram-positive (Bacillus spp., Clostridium spp.,
Micrococcus spp., Staphylococcus spp., Streptococcus spp.), and Gramnegative germs (Enterobacter cloacae, Escherichia coli, Klebsiella spp.,
Pseudomonas spp., Salmonella spp., Proteus spp.), fungi (Aspergillus
spp., Microsporum spp., Candida spp.) and viruses. It is not absorbed in
the intestine and it, therefore, neither enters the blood circulation, nor
deposits in the tissues. 99% of the amount ingested is excreted
completely and unmetabolised through the faeces.
INDICATIONS
Prevention of infections induced by Gram-positive and -negative germs on
pig and poultry farms; reduction of morbidity and mortality; increase in the
weight gain and decrease in the specific consumption; increase in the egg
production.
ADMINISTRATION AND DOSAGE
The uninterruptedly administered treatment ensures a permanent weight
gain increase.
Broiler chickens
Starters: 3.0 kg/t of feed (15 ppm).
Growers: 4.0 kg/t of feed (20 ppm).
Finishers: 2.0 kg/t of feed (10 ppm).
Breeders and layers
Young birds: 4.0 kg/t of feed (20 ppm).
Adult birds: 3.0-4.0 kg/t of feed (15-20 ppm).
Pseudomonosis prevention and control
All categories: 6.0 kg/t of feed (30 ppm).
Pigs
Growers, finishers: 4.0-6.0 kg/t of feed (20-30 ppm).
Finishers: 3.0 kg/t of feed (15 ppm).
PRECAUTIONS
It should be thoroughly homogenised in the feed before administration.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Paper sachet of 100 or 500 g, or paper bag of 1 or 5 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GERMOSTOP SHAMPOO
ANTIMICROBIAL AND DEODORISING SHAMPOO

COMPOSITION
Chlorhexidine digluconate
0.75 %
PHARMACOTHERAPEUTIC ACTIVITY
Chlorhexidine digluconate is a bisbiguanide derivative active against
Gram-positive and -negative germs and fungi. The antimicrobial effect is
quick, being manifest in cca 10-15 minutes. The product does not change
its suppleness, elasticity, colour or sensitivity. It confers the fur lustre and
a pleasant touch.
INDICATIONS
Dogs, cats, horses: Skin diseases (dry and wet seborrhoea, eczemata) or
uncomplicated superficial wounds.
USES
The entire surface is well massaged allowing the foam to be in contact
with the fur for 15-20 minutes, and then water rinsed. The procedure is
resumed only if necessary.
PRECAUTIONS
The contact with the eyes and conjunctival mucosa should be avoided.
In case of accidental contact, a water flush will be used to rinse.
The product ingestion and food contamination should be avoided.
It should be kept out of the reach of children.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 200 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GLUCOSE 10%
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Monohydrate glucose
100 mg
PHARMACOTHERAPEUTIC ACTIVITY
It is energising and readily absorbable; it improves the liver trophicity and
myocardial function, and increases diuresis.
INDICATIONS
Liver trophicity and support of the myocardial function of exhausted and
hypoglycaemic animals having been affected by intoxications,
enteropathies, ketonaemias, hepatites, myocardites and haemorrhages.
Also, traumatic or surgical shocks, burns, septicaemias, convalescent
animals.
ADMINISTRATION AND DOSAGE
5-10 ml of the hypertone 10% glucose solution are administered to pigs
either orally, or subcutaneously at 2 separate sites, or intraperitoneally but
only antibiotic-added for bacterial infections prevention. These doses may
be repeated 24 hours later if need be.
The isotone 5% glucose solution obtained by diluting 1:1 the 10% solution
with sterile distilled water (100 ml of the 10% solution are mixed, under
sterile conditions, with 100 ml of distilled water) is administered
subcutaneoulsy, intraperitoneally or intravenously for young animals
rehydration in enterites, bronchopneumonias, heavy haemorrhages and
as an energetic substrate.
Small animals: 2-10 g of glucose/day, i.e. 40-200 ml of the 5% solution or
20-100 ml of the 10% solution.
Medium sized animals: 10-40 g of glucose/day, i.e. 200-800 ml of the 5%
solution or 100-400 ml of the 10% solution.
Large animals: 20-120 g of glucose/day, i.e. 400-2400 of the 5% solution
or 200-1200 ml of the 10% solution.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 50, 100, 250 or 500 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GLUCOSE 33%
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Monohydrate glucose
330 mg
PHARMACOTHERAPEUTIC ACTIVITY
It is energising and readily absorbable; it improves the liver trophicity and
myocardial function, and increases diuresis.
INDICATIONS
Liver trophicity and support of the myocardial function of exhausted and
hypoglycaemic animals having been affected by intoxications,
enteropathies, ketonaemias, hepatites, myocardites and haemorrhages.
Also, traumatic or surgical shocks, burns, septicaemias, convalescent
animals.
ADMINISTRATION AND DOSAGE
Strictly intravenously (perivenously it induces necrosis) in daily doses of
60-400, 30-120 and 7-30 ml in large, medium sized and small animals
respectively. The treatment is repeated after 24 hours.
It may be subcutaneously or intraperitoneally inoculated to small and
medium sized animals after its dilution to 5% in distilled water or sterile
physiological saline.
CONTRAINDICATIONS
Renal insufficiencies.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 50, 100, 250 or 500 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

HELMIZOL A 2.5
ANTIPARASITIC SUSPENSION

COMPOSITION
Albendazole 2.5 %
PHARMACOTHERAPEUTIC ACTIVITY
Albendazole is an antiparasitic of wide action spectrum and high efficacy
in controlling trematodes, cestodes and nematodes in all their evolutional
forms (eggs, larvae, adults). Due to its low toxicity, albendazole does not
induce side effects even if the dose is 5 times higher.
INDICATIONS
Sheep, goats, young cattle: Prevention and treatment of gastrointestinal
nematodes (Haemonchus spp., Ostertagia spp., Trichostrongylus spp.,
Cooperia spp., Nematodirus spp., Toxocara spp. Bunostomum spp.,
Oesophagostomum spp.), and pulmonary ones (Dictyocaulus spp.,
Protostrongylidae spp.), Moniezia teniae, adult trematodes (Fasciola spp.,
Dicrocoelium spp.).
ADMINISTRATION AND DOSAGE
Orally, as follows:
Sheep, goats: 2 ml/10 kg of live weight (5 mg of albendazole/kg of live
weight).
Treatment of mature trematodes, Protostrongylidae infestations: 3 ml/10
kg of live weight (7.5 mg of albendazole/kg of live weight).
Wild ruminants: 3-4 ml/10 kg of live weight (7.5-10 mg of albendazole/kg
of live weight).
Young cattle: 30 ml/100 kg of live weight (7.5 mg of albendazole/kg of live
weight).
Treatment of mature trematodes, larval Ostertagia: 40 ml/100 kg of live
weight (10 mg of albendazole/kg of live weight).
Wild ruminants: 28-40 ml/100 kg of live weight.
Depending on the infestation type and intensity, the treatment may be
repeated 24 or 48 hours post administration I.
No special diet is needed before or after treatment.
CONTRAINDICATIONS
Females during the first gestational third.
PRECAUTIONS
The bottle should be well shaken before use.
It should be kept out of the reach of children.
WITHDRAWAL TIME
Meat: 10 days since the last administration.
Milk: 2 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 500, 1000 or 5000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

HELMIZOL A 10
ANTIPARASITIC SUSPENSION

COMPOSITION
Albendazole 10 %
PHARMACOTHERAPEUTIC ACTIVITY
Albendazole is an antiparasitic of wide action spectrum and high efficacy
in controlling trematodes, cestodes and nematodes in all their evolutional
forms (eggs, larvae, adults). Due to its low toxicity, albendazole does not
induce side effects even if the dose is 5 times higher.
INDICATIONS
Sheep, cattle: Prevention and treatment of gastrointestinal nematodes
(Haemonchus spp., Ostertagia spp., Trichostrongylus spp., Cooperia spp.,
Nematodirus spp., Toxocara spp. Bunostomum spp., Oesophagostomum
spp.), and pulmonary ones (Dictyocaulus spp., Protostrongylidae spp.),
Moniezia teniae, adult trematodes (Fasciola spp., Dicrocoelium spp.).
ADMINISTRATION AND DOSAGE
The administration is oral: 1 ml of suspension corresponds to 85 mg of
albendazole.
Cattle, sheep: 10 ml/100 kg of body weight.
Treatment of mature trematodes and larval Ostertagia: 12 ml/100 kg of
body weight (10 mg of albendazole/kg of body weight).
Depending on the infestation type and intensity, the treatment may be
repeated 24 or 48 hours post administration I.
CONTRAINDICATIONS
Females during the first gestational third.
PRECAUTIONS
The bottle should be well shaken before use.
It should be kept out of the reach of children.
WITHDRAWAL TIME
Meat: 10 days since the last administration.
Milk: 2 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 500, 1000 or 5000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

HELMIX
ANTIPARASITIC PREMIX

COMPOSITION
1 gram contains:
Albendazole 60 mg
PHARMACOTHERAPEUTIC ACTIVITY
Albendazole is a broad spectrum anthelmintic active against cestodes,
trematodes and nematodes in all their evolutional forms (eggs, larvae,
adults). Albendazole blocks the enzymatic systems that activate glucose
metabolism. Orally administered, it is readily absorbed and spreads to all
the organs and tissues inducing the helminths lysis, irrespective of the
animal species and category and of the parasites localisation. It is mainly
excreted through urine. This product toxicity is low, doses 5 times higher
than the common therapeutic ones being tolerated.
INDICATIONS
Prophylaxy and treatment of nematodes in:
Poultry:
Ascaridia galli, Heterakis gallinae, Capillaria spp., Syngamus
trachea.
Pigs: Ascaris
suum,
Oesophagostomum,
Trichocephalus
suis,
Metastrongylus, Trichinella spiralis.
ADMINISTRATION AND DOSAGE
Pigs: 1.7-2 g/10 kg of body weight/day fed for 2 consecutive days, with
repetition every trimester.
Trichinellosis control (all the herd): Treatment I for 3 consecutive days;
treatments II, III and IV for 2 consecutive days each month; treatment V
for 1 day each month for 5-6 months. The treatment is discontinued at
least 3 months since the last case of trichinellosis was recorded.
Poultry: 1 g/6 kg of body weight/day (10 mg of albendazole/kg of body
weight/day), or 2 kg/t of feed, with repetition the following day.
CONTRAINDICATIONS
Animals during gestation month I, or during service.
WITHDRAWAL TIME
Meat: 10 days since the last administration.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Plastic bottle of 100 g, or can of 1, 5 or 20 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

INDOMETHACIN
SUPPOSITORIES

COMPOSITION
Indomethacin 0.020 g
PHARMACOTHERAPEUTIC ACTIVITY
Indomethacin is anti-inflammatory, -rheumatic, -pyretic, and analgesic.
INDICATIONS
Dogs: Rheumatic and traumatic inflammations and pains.
ADMINISTRATION AND DOSAGE
Rectally :1 suppository/day for 3-5 days.
CONTRAINDICATIONS
Animals that are hypersensitive to nonsteroid anti-inflammatories.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box of 2 blister foils x 6 suppositories.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

IODINE TINCTURE
EXTERNAL SOLUTION

COMPOSITION
Iodine
2g
Potassium iodine p.a.
3g
o
Ethyl alcohol (50 ) up to 100 ml
PHARMACOTHERAPEUTIC ACTIVITY
The iodine tincture acts as a bacteriostatic, bactericide and irritantrevulsive.
INDICATIONS
Disinfection of the surgical area and injections rooms; asepsy of small
superficial wounds, ulcers, fistulae, paronychia, favus, actinomycosis,
articular conditions, etc.
ADMINISTRATION
Surgical areas, lesions, inflammatory foci: Tamponing or painting.
Actinomycosis: Inoculation into abscesses and phlegmons, followed by
paintings once these open and empty.
Revulsive: Frictions and paintings around the painful joints, wounds or
inflamed areas.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 400 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

IODOFORMED ETHER 5 %
EXTERNAL SOLUTION

COMPOSITION
Iodoform
5g
PHARMACOTHERAPEUTIC ACTIVITY
Iodoform is not antibacterial by itself. In contact with the wounds and
under the action of the tissular secretions, of microorganisms and of their
products and in the presence of light and oxygen, it slowly and
progressively releases iodine that has long-term antiseptic properties. It
stimulates wounds granulation, diminishes secretions; also, it has a
deodorant and an analgesic effect.
INDICATIONS
Treatment of superficial or deep cutaneous wounds, ulcers, fistulae,
pododermatites.
ADMINISTRATION
Painting or spraying of superficial or deep wounds of various localisations.
PRECAUTIONS
It should not be applied on mucosae or in the ocular area.
STORAGE
At 2-8oC, protected from light, fire and heat.
PACKAGING
Brown bottle of 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

IOD - POVIDONA 10%


DISINFECTING SOLUTION

COMPOSITION
Aqueous solution of IOD-POVIDONA 10% (equivalent to 1% active iodine)
under the form of a soluble iodine-polyvinylpyrrolidone complex.
PHARMACOTHERAPEUTIC ACTIVITY
The product is an iodophor of a high penetration capacity and prolonged
bactericidal and fungicidal effects due to the progressive release of iodine.
The iodine-polyvinylpyrrolidone complex is harmless to the living tissues
which recommends it in oral and muco-membranous infections. Besides
its own effect in preventing and treating dermatological infections, the
product is also the best alternative to the antibiotics recommended in such
cases.
INDICATIONS
The 10% solution: Cleansing of contaminated wounds and dermic
surfaces, treatment of vaginal candidoses and trichomonoses, mycotic
infections and those of the derm caused by nematodes.
The 7.5% solution (75 ml of IOD-POVIDONA 10% diluted in 25 ml of distilled
water): Detergent for pre-surgical scrubbing, disinfectant of hands
(before surgeries) and of surgical instruments.
The 1% solution (10 ml of IOD-POVIDONA 10% diluted in 90 ml of distilled
water): Preventively, in oral infections.
Animal drinking water purification: 100 ml in 200 l of water.
STORAGE
At 2-15oC, protected from light.
PACKAGING
Bottle of 100 or 1000 ml, or can of 5 l.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

IVER - MITE OTIC


OTIC SOLUTION

COMPOSITION
Ivermectin 0.003 %
PHARMACOTHERAPEUTIC ACTIVITY
Ivermectin is an antiparasitic inhibiting the signals transmission from the
ventral cord neurons to the motor ones by stimulating the gamma-aminobutyric acid (GABA) release. As for its pharmacodynamic activity, it is a
scabicide.
INDICATIONS
Dogs, cats: Prophylaxis and treatment of auricular scabies.
ADMINISTRATION
The animals ear is cleaned with OTTO CLEANS, a cerumenolytic solution.
2-5 drops of the product are instilled and the ear basis is slightly
massaged. A few minutes later, the product excess is removed by slight
tamponing with absorbent cotton.
Four treatments are applied 3 days apart or as directed by the
veterinarian.
PRECAUTIONS
It should be kept out of the reach of children.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Dropper bottle of 7.5 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

IVER - MIX
ANTIPARASITIC PREMIX

COMPOSITION
Ivermectin 0.6%
PHARMACOTHERAPEUTIC ACTIVITY
In nematodes, ivermectin stimulates the production of gamma
aminobutyric acid (GABA) interrupting thus the nervous influx
transmission, paralysing and killing the parasite. In arthropods, the
nervous influx is interrupted at the neuro-muscular synapses, resulting in
the parasites paralysis and death. The product accumulates in the
auricular cerumen, the harbouring place of Sarcoptes scabiei var suis.
INDICATIONS
Young pigs: Prophylaxis and treatment of gastrointestinal (Ascaris suum,
Hyostrongylus rubidus, Oesophagostomum spp., Strongyloides ransomi,
Trichuris suis), pulmonary (Metastrongylus spp.), and renal nematodes
(Stephanurus dentatus), of lice and mites (Sarcoptes scabiei).
ADMINISTRATION AND DOSAGE
Pigs whose daily consumption averages at least 5% of the live weight: 2g
(2 ppm) of ivermectin/t of feed/ day (100 mcg of ivermectin/kg of live
weight/day) for 7 days.
This concentration is obtained by adding 333 g of the product to each ton
of feed. For a good homogenisation, a premix will be made of 1 kg of the
product and 14 kg of feed, to be then added at a 5 kg/t of feed ratio.
With the pigs under restrictive feeding, with protein rich rations and whose
daily feed consumption averages below 5% of the live weight, the
ivermectin dose has to be increased.
The calculation is as follows:
Dose (ppm) = x : 10, where x = mean live weight (kg) divided to the daily
feed consumption.
CONTRAINDICATIONS
Other animal species.
Pigs over 100 kg.
WITHDRAWAL TIME
Pork: 5 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 100 or 500 g, or can of 1 or 5 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LINCOMYCIN 4.4%
PREMIX

COMPOSITION
Lincomycin (as hydrochloride) 4.4 %
PHARMACOTHERAPEUTIC ACTIVITY
Lincomycin is an antibiotic active against Gram-positive and -negative germs
[Staphylococcus spp., Streptococcus spp., Erysipelothrix rhusiopathiae, Clostridium spp.,
Bordetella spp., Actinomyces spp., Actinobacillus spp., Corynebacterium spp.,
Haemophilus spp., Escherichia coli, Mycoplasma hyopneumoniae, Brachyspira
(Serpulina, Treponema) hyodysenteriae, Lawsonia]. Upon the oral administration, it is
resorbed from the digestive tract at a 20-30% ratio.
INDICATIONS
Pig and poultry carcasses: Improvement of the weight gain and organoleptic qualities.
Pigs: Prophylaxis and treatment of infectious dysentery and enzootic pneumonia.
Poultry: Prophylaxis and treatment of necrotic enteritis.

ADMINISTRATION AND DOSAGE


Pigs
Weight gain and carcass organoleptic qualities improvement: 0.5 kg of premix/t of feed
from weaning to slaughter.
Infectious dysentery prevention: 1 kg of premix/t of feed.
Associated anaerobic infections prevention and treatment: 2.5 kg of premix/t of feed for
3 weeks.
Enzootic pneumonia prevention: 1 kg of premix/t of feed.
Enzootic pneumonia treatment: 5 kg of premix/t of feed for 21 days.
Poultry
Weight gain and carcass organoleptic qualities improvement: 50-250 g of premix/t of
feed throughout the growing period.
Necrotic enteritis control: 50-100 g of premix/t of feed throughout the growing period.
Necrotic enteritis treatment: 0.5-1 kg of premix/t of feed for 7 days.

CONTRAINDICATIONS
Hamsters, rabbits, ruminants or horses as their ingesting of lincomycin might lead to
severe gastrointestinal disorders.
SIDE EFFECTS
Pigs: Occasionally, soft faeces and/or a slight inflammation of the anus or skin
congestion may occur; they disappear after 5-8 days with no need of treatment
discontinuance.
PRECAUTIONS
It should be well homogenised in the feed before usage.
WITHDRAWAL TIME
Pork: Piglets administered 2.5 kg of premix/t of feed: 1 day since the last administration.
: Piglets administered 5 kg of premix/t of feed: 6 days since the last administration.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Sachet of 100, 500 or 1000 g, or sack of 20 kg.
MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LINCOMYCIN 11%
PREMIX

COMPOSITION
Lincomycin (as hydrochloride)

11 %

PHARMACOTHERAPEUTIC ACTIVITY
Lincomycin is an antibiotic active against Gram-positive and -negative germs
[Staphylococcus spp., Streptococcus spp., Erysipelothrix rhusiopathiae, Clostridium spp.,
Bordetella spp., Actinomyces spp., Actinobacillus spp., Corynebacterium spp.,
Haemophilus spp., Escherichia coli, Mycoplasma hyopneumoniae, Brachyspira
(Serpulina, Treponema) hyodysenteriae, Lawsonia]. Following the oral administration, it
is resorbed from the digestive tract at a 20-30% ratio.
INDICATIONS
Pig and poultry carcasses: Improvement of the weight gain and organoleptic qualities.
Pigs: Prophylaxis and treatment of infectious dysentery and enzootic pneumonia.
Poultry: Prophylaxis and treatment of necrotic enteritis.

ADMINISTRATION AND DOSAGE


Pigs
Infectious dysentery prevention: 1 kg of premix/2.5 t of feed.
Associated anaerobic infections prevention and treatment: 1 kg of premix/t of feed for 3
weeks.
Enzootic pneumonia treatment: 2 kg of premix/t of feed for 21 days.
Poultry
Weight gain and carcass organoleptic qualities improvement: 20-40 g of premix/t of feed
throughout the growing period.
Necrotic enteritis control: 20-40 g of premix/t of feed throughout the growing period.
Necrotic enteritis treatment: 200-400 g of premix/t of feed for 7 days.

CONTRAINDICATIONS
Hamsters, rabbits, ruminants or horses as their ingesting of lincomycin might lead to
severe gastrointestinal disorders.
SIDE EFFECTS
Pigs: Occasionally, soft faeces and/or a slight inflammation of the anus or skin
congestion may occur; they disappear after 5-8 days with no need of treatment
discontinuance.
PRECAUTIONS
It should be well homogenised in the feed before usage.
WITHDRAWAL TIME
Pork: Piglets administered 1 kg of premix/t of feed: 1 day since the last administration.
: Pigs administered 2 kg of premix/t of feed: 6 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Sachet of 100, 500 or 1000 g, or sack of 20 kg.
MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LINCOMYCIN 100
TABLETS

COMPOSITION
1 tablet contains:
Lincomycin (as hydrochloride)
100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Lincomycin is a bacteriostatic antibiotic active against Gram-positive
germs (Staphylococcus spp., Streptococcus spp., Pneumococcus spp.),
mycoplasma germs or anaerobic ones. Lincomycin diffuses well into the
tissues and penetrates rather well even the bones and joints. The
maximum concentration upon the oral administration is reached after 2-4
hours.
INDICATIONS
Dogs: Primary or associated bacterial laryngitis or tonsillitis,
streptococcal or staphylococcal dermatitis, metrites, secondary bacterial
infections associated with distemper, Rubarths hepatitis, and
parvovirosis.
Cats: Infections associated with digestive and respiratory viroses
(rhinotracheitis, parvoviral leucopenia, calicivirus-induced pneumonia),
skin infections (abscesses).
ADMINISTRATION AND DOSAGE
1 tablet/5 kg of body weight (20 mg of lincomycin/kg of body weight) every
12 hours for 3-5 days.
The treatment may be prolonged up to 12 days in case of severe
diseases, staphylococcal dermatites, deep suppurative osteomyelitis.
CONTRAINDICATIONS
Cats and dogs that are hypersensitive to lincomycin.
Laboratory animals (guinea pigs, hamsters, rabbits) and horses.
SIDE EFFECTS
Occasional vomiting and vomituritions may occur in cats.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Bottle of 50 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LINCOMYCIN 200
TABLETS

COMPOSITION
1 tablet contains:
Lincomycin (as hydrochloride)
200 mg
PHARMACOTHERAPEUTIC ACTIVITY
Lincomycin is a bacteriostatic antibiotic active against Gram-positive
germs (Staphylococcus spp., Streptococcus spp., Pneumococcus spp.),
anaerobic germs and mycoplasmas. Lincomycin diffuses well into the
tissues and penetrates rather well even the bones and joints. The
maximum concentration upon the oral administration is reached after 2-4
hours.
INDICATIONS
Dogs: Primary or associated bacterial laryngitis or tonsillitis,
streptococcal or staphylococcal dermatitis, metrites, secondary bacterial
infections associated with distemper, Rubarths hepatitis, and
parvovirosis.
Cats: Infections associated with digestive and respiratory viroses
(rhinotracheitis, parvoviral leucopenia, calicivirus-induced pneumonia),
skin infections (abscesses).
ADMINISTRATION AND DOSAGE
1 tablet/10 kg of body weight (20 mg of lincomycin /kg of body weight)
every 12 hours for 3-5 days.
The treatment may be prolonged up to 12 days in case of severe
diseases, staphylococcal dermatites, deep suppurative osteomyelitis.
CONTRAINDICATIONS
Cats and dogs that are hypersensitive to lincomycin.
Laboratory animals (guinea pigs, hamsters, rabbits) and horses.
SIDE EFFECTS
Occasional vomiting and vomituritions may occur in cats.
STORAGE
At 15-25o C, protected from light and humidity.
PACKAGING
Bottle of 50 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LINCOMYCIN - SPECTINOMYCIN 2.2 %


PREMIX

COMPOSITION
1 gram contains:
Lincomycin (as hydrochloride)
11 mg
Spectinomycin (as sulphate)
11 mg
Excipient
up to 1 g
PHARMACOTHERAPEUTIC ACTIVITY
Lincomycin is a lincosamidic bacteriostatic antibiotic active against Grampositive germs (Streptococcus spp., Staphylococcus spp., Diplococcus
spp., Pneumococcus spp., Campylobacter spp., Corynebacterium
diphtheriae, Clostridium spp.) and some anaerobic microorganisms.
Spectinomycin is bacteriostatic against many Gram-negative germs and
mycoplasmas.
INDICATIONS
Pigs: Prophylaxis and treatment of dysentery, enterites, pulmonary
infections, arthrites. Stimulation of the weight gain during the growing
period.
Hens, turkey cocks: Prophylaxis and treatment of respiratory diseases
(chronic respiratory disease, coryza). Improvement of the weight gain
and pigmentation; the control of necrotic enteritis.
ADMINISTRATION AND DOSAGE
Pigs
Prophylaxy: 2 kg of premix/t of feed for 7-21 days.
Treatment: 4 kg of premix/t of feed for 14-21 days.
Growth promoter: 1 kg of premix/t of feed.
Poultry
Prevention, growth promoter: 1 kg/t of feed.
Treatment: 5 kg/t of feed for 7-10 days.
CONTRAINDICATIONS
Hypersensitivity to lincomycin or spectinomycin.
Ruminants, horses, rabbits.
SIDE EFFECTS
Pigs: Occasionally, soft faeces and/or a slight inflammation of the anus or
skin congestion may occur; they disappear after 5-8 days with no need of
treatment discontinuance.
PRECAUTIONS
It should be well homogenised before administration.
The simultaneous administration of other drugs should be avoided.
Only medicated feed will be administered throughout the administration.
WITHDRAWAL TIME
Pork: 7 days since the last administration.
Poultry meat: 3 days since the last administration.
STORAGE
At 15-25o C, protected from light and humidity.
PACKAGING
Sachet of 100, 500 or 1000 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LINCOMYCIN - SPECTINOMYCIN 4.4 %


PREMIX

COMPOSITION
1 gram contains:
Lincomycin (as hydrochloride)
22 mg
Spectinomycin (as sulphate)
22 mg
Excipient
up to 1 g
PHARMACOTHERAPEUTIC ACTIVITY
Lincomycin is a lincosamidic bacteriostatic antibiotic active against Grampositive germs (Streptococcus spp., Staphylococcus spp., Diplococcus
spp., Pneumococcus spp., Campylobacter spp., Corynebacterium
diphtheriae, Clostridium spp.) and some anaerobic microorganisms.
Spectinomycin is bacteriostatic against many Gram-negative germs and
mycoplasmas.
INDICATIONS
Pigs: Prophylaxis and treatment of dysentery, enterites, pulmonary
infections, arthrites. Stimulation of the weight gain during the growing
period.
Hens, turkey cocks: Prophylaxis and treatment of mycoplasma-induced
respiratory diseases. Improvement of the weight gain and pigmentation;
the control of necrotic enteritis.
ADMINISTRATION AND DOSAGE
Pigs
Prophylaxy: 1 kg of premix/t of feed for 7-21 days.
Treatment: 2 kg of premix/t of feed for 14-21 days.
Growth promoter: 0.5 kg of premix/t of feed.
Poultry
Prevention, growth promoter: 0.5 kg/t of feed.
Treatment: 2.5 kg/t of feed for 7-10 days.
CONTRAINDICATIONS
Hypersensitivity to lincomycin or spectinomycin.
Ruminants, horses, rabbits.
SIDE EFFECTS
Pigs: Occasionally, soft faeces and/or a slight inflammation of the anus or
skin congestion may occur; they disappear after 5-8 days with no need of
treatment discontinuance.
PRECAUTIONS
It should be well homogenised before administration.
The simultaneous administration of other drugs should be avoided.
Only medicated feed will be administered throughout the administration.
WITHDRAWAL TIME
Pork: 7 days since the last administration.
Poultry meat: 3 days since the last administration.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Sachet of 100, 500 or 1000 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LINCOVET 10
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Lincomycin (as hydrochloride)
100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Lincomycin is an antibiotic active against Gram-positive and -negative
germs [Staphylococcus spp., Streptococcus spp., Erysipelothrix spp.,
Clostridium spp., Bordetella spp., Actinomyces spp., Actinobacillus spp.,
Corynebacterium spp., Haemophilus spp., Escherichia spp., Mycoplasma
spp., Lawsonia spp., Brachyspira (Serpulina, Treponema) spp.]. It diffuses
well into the tissues, even into the weakly irrigated ones where it is readily
adsorbed. Although a bacteriostatic, it is bactericidal if twice or three times
higher doses are administered.
INDICATIONS
Pigs: Enterites, erysipelas, pneumonias, arthrites.
Cattle: Enterites, pneumonias.
Sheep, goats: Infectious pododermatitis.
Poultry: Chronic respiratory disease, contagious coryza, aerosacculitis of
turkeys, infectious synovitis, bacterial enterites and arthrites.
Dogs: Primary or associated bacterial tonsillitis and laryngitis,
streptococcal or staphylococcal dermatitis, metrites, secondary bacterial
infections associated with distemper, Rubarths hepatitis and
parvovirosis.
Cats: Infections associated with digestive and respiratory viroses
(rhinotracheitis, parvoviral leucopoenia, calicivirus-induced pneumonia),
skin infections.
ADMINISTRATION AND DOSAGE
Cattle, pigs, sheep, goats: 1ml/10 kg of live weight/day for 3-7
consecutive days by the intramuscular route.
Dogs, cats: 1ml/5 kg of live weight either daily or twice a day for 3-5
consecutive days by the intramuscular, subcutaneous or intravenous
route.
Poultry: 0.5 ml/2.5 kg of live weight by the subcutaneous route.
CONTRAINDICATIONS
Animals allergic to lincomycin.
Laboratory animals (rabbits, hamsters, guinea pigs), horses.
SIDE EFFECTS
Sheep, goats, pigs: Transient diarrhoea.
Goats: A loss of appetite and a decrease in the milk yield may occur.
WITHDRAWAL TIME
Meat: 7 days since the last administration.
Milk: 48 hours since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LIN - SPE - MIX 22


PREMIX

COMPOSITION
1 g contains:
Lincomycin (as hydrochloride)
11 mg
Spectinomycin (as sulphate)
11 mg
PHARMACOTHERAPEUTIC ACTIVITY
Lincomycin is a lincosamidic bacteriostatic antibiotic active against Grampositive germs (Streptococcus spp., Staphylococcus spp., Diplococcus
spp., Pneumococcus spp., Campylobacter spp., Corynebacterium
diphtheriae, Clostridium spp.) and some anaerobic microorganisms.
Spectinomycin is bacteriostatic against many Gram-negative germs and
mycoplasmas.
INDICATIONS
Pigs: Prophylaxis and treatment of dysentery, enterites, pulmonary
infections, arthrites. Stimulation of the weight gain during the growing
period.
Hens, turkey cocks: Prophylaxis and treatment of respiratory diseases.
Improvement of the weight gain and pigmentation; the control of necrotic
enteritis.
ADMINISTRATION AND DOSAGE
Pigs
Prophylaxy, growth promoter: 2 kg of premix/t of feed.
Treatment: 4 kg of premix/t of feed for 7 days.
With chronic cases, the therapy may be extended to 2-3 weeks.
Poultry
Prevention, growth promoter: 1 kg/t of feed.
Treatment: 4 kg/t of feed for 7-10 days.
CONTRAINDICATIONS
Hypersensitivity to lincomycin or spectinomycin.
Ruminants, horses, rabbits.
SIDE EFFECTS
Pigs: Occasionally, soft faeces and/or a slight inflammation of the anus or
skin congestion may occur; they disappear after 5-8 days with no need of
treatment discontinuance.
PRECAUTIONS
It should be well homogenised before administration.
The simultaneous administration of other drugs should be avoided.
WITHDRAWAL TIME
Pork: 7 days since the last administration.
Poultry meat: 3 days since the last administration.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Sachet of 100, 500 or 1000 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

MAGNESIUM SULPHATE
25% INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Magnesium sulphate
250 mg
PHARMACOTHERAPEUTIC ACTIVITY
The solution of magnesium sulphate is, administered parenterally, a
depressor of the central nervous system.
INDICATIONS
Treatment of metabolic hypomagnesaemias particularly in cattle:
Magnesium deficiency, nutritional tetany, complementary treatment in
metabolic acidosis.
Also, as a depressive administered parenterally in equine colics and
tetanus, canine chorea, and for hypnosis or basal narcosis in systemic
anaesthesias with chloral hydrate.
ADMINISTRATION AND DOSAGE
Cattle hypomagnesaemias: 50 ml/100 kg of live weight, by the
intravenous or subcutaneous route. To avoid any unwanted reactions,
half of this dose is recommended to be intravenously inoculated, and the
other half subcutaneously.
Colics, anasarca, narcosis adjuvant: 6-7.5 g (25-30 ml) and 1-2 g (4-8
ml) for large animals and dogs respectively, by the intravenous or
subcutaneous (at several sites) route.
Equine tetanus and diaphragmatic chorea: 30 g (120 ml)/day,
intravenously.
Canine chorea: 0.5-1.25 g (2-5 ml), intramuscularly.
Chloral hydrate-associated narcosis adjuvant for horses: 0.07-0.1 g/kg
(0.28-0.40 ml), intravenously. In case of overdosing, or for
dehypnotising, a calcium chloride solution is intravenously
administered.
PRECAUTIONS
Overdosing should be avoided.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 20, 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

MASTIKER E
INTRAMAMMARY SUSPENSION

COMPOSITION
A syringe contains:
Erythromycin base 300 mg
Excipients
up to 6 ml
PHARMACOTHERAPEUTIC ACTIVITY
Erythromycin is a macrolide antibiotic mainly acting against the Gram-positive
bacteria inducing 99% of mastites (Staphylococcus aureus, Streptococcus
agalactiae, Streptococcus dysgalactiae, Streptococcus uberis). It acts
bacteriostatically at the infection site and readily penetrates the mammary
parenchymatous wall.
INDICATIONS
Prevention and treatment of clinical, acute or chronic mastites during the
lactation period.
ADMINISTRATION
The udder is completely milked, each mamilla is washed with an antiseptic
solution, such as GERMOSTOP FOR THE UDDER.
The syringe content is brought to the body temperature and the protection
lid is then removed.
The syringe tip is introduced into the galactophorus duct of the affected
quarter that is massaged for a good suspension distribution.
The cow will not be milked for at least 6 hours post administration.
The treatment may be repeated at a 12-24 hours interval depending on
the mastitis type.
PRECAUTIONS
The syringe content will be brought to 25-35oC.
The milk milked during the treatment will not be consumed.
WITHDRAWAL TIME
Milk: 3 days (6 milkings) since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Disposable polyethylene syringe of 6 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

MEDIODINE SCRUB
LIQUID SCRUB

COMPOSITION
Polyoxyethylene-iodine phenol complex equivalent to free iodine
0.75%
PHARMACOTHERAPEUTIC ACTIVITY
It is a scrubbing product based on a iodine complex with tensio-active
substances, that is bactericidal, virucidal and fungicidal through the
combination of the bactericidal and virucidal activities of iodine with the
cleansing one of the tensio-active substances. The organic iodine complex
is water-miscible at any proportion. Its advantage is that keeps iodine in
the solution, slowly releasing it in contact with the tissues. It is germicidal
with a 1-6 minutes latency and a prolonged duration. It is also active in the
presence of organic matters (blood, serum, pus, necrosed tissue); it is not
irritant as the classical iodine forms (tinctures) are or corrosive at the
commonly used concentrations, and it washes off readily without staining.
INDICATIONS
Pre-operative antisepsis of skin and mucosae (the conjunctival mucosa
excluded).
Pre- and post-operative scrubbing of the surgeons and supporting staffs
hands and cleansing of the surgical area.
Washing of infected wounds, burns; soaking of tents for venous punctions.
Washing of bacterial or fungal dermatoses-affected skin areas before
applying the specific treatment.
If currently used, it prevents the infecting of mechanical and thermal
lesions (cuts, scratches, sores, burns).
As it is a long-acting product, there is no need of repeated topical
application.
USES
Pre-operative surgeons hands scrubbing: Cca 5 cm3. A brush is also
used for better scrubbing under the nails as well. A little water is then
added for a rich foaming, and the scrubbing is continued.
Pre-operative cleansing of surgical areas: Cca 1cm3/120-190 cm3. The
area is carefully scrubbed, the resulting foam is removed with a sterile
gauze soaked in water or a saline solution. After repeating the
procedure, MEDIONINE SOLUTION is applied and allowed to dry up.
CONTRAINDICATIONS
Conjunctival mucosa.
PRECAUTIONS
It should be used with precaution for deep wounds or burns.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Brown plastic or glass bottle of 200, 500 or 1000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

MEDIODINE SOLUTION
ANTISEPTIC SOLUTION

COMPOSITION
Polyoxyethylene-iodine phenol complex equivalent to free iodine
0.75%
Excipient
up to 100%
PHARMACOTHERAPEUTIC ACTIVITY
It is a scrubbing product based on a iodine complex with tensio-active
substances, that is bactericidal, virucidal and fungicidal through the
combination of the bactericidal and virucidal activities of iodine with the
cleansing one of the tensio-active substances. The organic iodine complex
is water-miscible at any proportion. Its advantage is that keeps iodine in
the solution, slowly releasing it in contact with the tissues. It is germicidal
even in the presence of blood, pus and serum with a 1-6 minutes latency
and a prolonged duration. It is also active in the presence of organic
matters (blood, serum, pus, necrosed tissue); it is not irritant as the
classical iodine forms (tinctures) are or corrosive at the commonly used
concentrations, and it washes off readily without staining.
INDICATIONS
Pre-operative preparation of the skin and mucosae (except the
conjunctival one).
Disinfection of excoriations, superficial wounds and burns.
Prevention of post surgical infections in case of incisions.
USES
A film is applied with a sterile gauze on the surface to be prepared for the
surgery.
In case of wounds, the solution is applied once or twice a day until the
wounds are healed and may be bandaged (the iodine-caused pressure is
very low in comparison with the classical iodine tinctures).
The solution applied topically does not smart, damage or irritate the skin
and mucosae, and it is readily washed off.
CONTRAINDICATIONS
Conjunctival mucosa.
SIDE EFFECTS
In case of a prolonged application, local irritations and very rare superficial
burns may occur; the treatment should be discontinued and a veterinarian
consulted.
PRECAUTIONS
It should be used precautiously in the case of deep wounds or burns.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Brown plastic or glass bottle of 200, 500 or 1000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

METHIONINE
TABLETS

COMPOSITION
1 tablet contains:
DL-methionine
250 mg corresponding to 3.35 mEq of methionine
PHARMACOTHERAPEUTIC ACTIVITY
DL-methionine is an essential amino acid with sulphur acting in the
metabolism of lipids and proteins. It prevents or corrects the liver fat
deposits by correcting the choline deficiency. It has an acidifying effect on
urine.
OTHER DRUGS INTERACTIONS
Urine acidification may increase the renal secretion of quinidine.
The antibiotics of the aminoglycosides group (gentamycin) and of the
macrolides one (erythromycin) are more efficient in an alkaline medium.
The urine acidifying may diminish these drugs efficacy in treating some
infections of the urinary tract.
INDICATIONS
Urine acidifying.
Prevention and treatment of urinary lithiasis.
Reduction of the ammonia odour intensity of urine.
Liver protection by hindering the hepatic fatty degenerescence.
ADMINISTRATION AND DOSAGE
Orally, either as such or in the feed or broken up.
Adult cats: 0.75-1.5 tablet/kg of body weight (2.5-5 mEq/kg)/day.
Medium-sized (4 kg) cats: 3-6 tablets (10-20 mEq)/day without, in any
case, exceeding 2 g of methionine/day (8 tablets).
Dogs: 0.5 -1 tablet/kg of body weight (2-4 mEq/kg)/day.
Small dogs (below 7 kg): 1-8 tablets/day.
Medium sized (7-15 kg) dogs: 4-14 tablets/day.
Large dogs (15-30 kg) : 10-25 tablets/day.
CONTRAINDICATIONS
Animals with renal acidosis, hepatic insufficiency (DL-methionine may
induce a hypersecretion of mercaptan-like compounds aggravating a
hepatic crisis symptoms leading even to a hepatic coma), pancreas
diseases.
Kittens !
SIDE EFFECTS
Anorexia, methaemoglobinaemia, haemolytical anaemia, ataxia and
cyanosis were recorded with mature cats administered 2 g of DLmethionine (8 tablets) a day. Rarely, gastrointestinal troubles were
noticed. In such cases, the tablets will be either administered during or
after the feeding, or in 2-3 portions.
PRECAUTIONS
Methionine may be toxic if overdosed.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Plastic bottle of 75 or 150 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

METHYLENE BLUE 1%
SOLUTION

COMPOSITION
Methylene blue
1%
PHARMACOTHERAPEUTIC ACTIVITY
The product has a long-term, moderate, antiseptic activity; it readily
penetrates the lesioned tissues (wounds, burns, the pharynx, buccal
mucosa, etc.) on which it has, upon repeated applications, on analgetic
effect, while favouring healing. Administered in the drinking water, it is
rapidly absorbed from the digestive tract, activating the oxidoreducing
processes in the organism.
INDICATIONS
Hypoxias, methaemoglobinaemias, sulphonamides poisonings.
When glucose-associated, it favours glucose oxidation, allowing the rapid
energising of hypodynamic animals.
It is urine eliminated and acts as an antiseptic of the urinary tract, turning
urine green-bluish.
It is also used as a stain in microbiology.
ADMINISTRATION AND DOSAGE
Curatively in birds: 100 ml in 4-5 l of drinking water for 2-3 days.
Prophylactically: 100 ml in 10-15 l of drinking water.
Topically (wounds, skin burns): 0.7% hydroalcoholic solution obtained by
diluting the 1% solution in distilled water.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 50, 100, 200 or 400 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

MICOCID
SOLUTION

COMPOSITION
Phenol
5%
Adjuvants
2%
PHARMACOTHERAPEUTIC ACTIVITY
It is a potent antimycotic and bactericide due to its components.
INDICATIONS
Topical treatment of bovine trichophytosis.
USES
The trichophytic lesions are soaked with the solution, their contour being
exceeded by cca 1 cm. Healing occurs after 1-3 treatments applied 3-5
days apart depending on the severity and localisation of the small
circumscribed trichophytic lesions.
PRECAUTIONS
The contact with the ocular mucosa and hands should be avoided. The
accidental ingestion may lead to intoxications.
STORAGE
At 15-25o C, protected from light.
PACKAGING
Bottle of 200, 500 or 1000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

MICODERMIN
OINTMENT

COMPOSITION
Neomycin sulphate 0.5 g
Nystatin
2.0 g
Hydrocortisone
0.1 g
Excipient
up to 100.0 g
PHARMACOTHERAPEUTIC ACTIVITY
It is antibacterial, antifungal and anti-inflammatory due to neomycin,
nystatin and hydrocortisone respectively.
INDICATIONS
All species: Cutaneous conditions of fungal and bacterial aetiology.
ADMINISTRATION AND DOSAGE
The lesions are thinly applied, after cleansing, with the ointment at a
frequency depending on the nature and severity of the cases.
Less severe conditions: Once a day for a week.
Severe conditions: 2-3 times a day for 8 days or more.
PRECAUTIONS
Prolonged treatments should be avoided.
CONTRAINDICATIONS
Ocular conditions.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Plastic box of 50 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

MICOVIT
POWDER

COMPOSITION
Nystatin
Phthalylsulfathia
zole
Vitamin B1
Vitamin B2
Vitamin B6
Vitamin B12
Lactose

33.000 g
400.000 g

6.000 g
6.000 g
14.000 g
0.040 g
up to
1000.000 g
PHARMACOTHERAPEUTIC ACTIVITY
Nystatin is a polyene antibiotic; its activity spectrum includes moulds and
fungi known to multiply asexually that induce superficial mycoses.
Phthalylsulfathiazole is a bacteriostatic sulphonamide with a low digestive
absorption, that is recommended in gastrointestinal infections.
INDICATIONS
Suckling pigs: Mycotic diarrhoea.
ADMINISTRATION AND DOSAGE
An aqueous 20% suspension is prepared extempore of which 2-3 ml are
administered daily for 3-5 days.
1 kg/t of compound feed (1g/kg) after an intermediary premix.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Hydrophobic paper sack of 1-25 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

MITE EMULSION
ANTIPARASITIC OTIC EMULSION

COMPOSITION
Permethrin 0.15 %
PHARMACOTHERAPEUTIC ACTIVITY
Permethrin is a contact, synthetic, insecticide, acaricide, pediculicide and
scabicide pyrethroid toxic to the ectoparasitic neuromuscular system. It is a
little toxic to homeothermals.
INDICATIONS
Dogs and cats: Auricular scabies.
ADMINISTRATION
The animals ears are cleaned with OTTO CLEANS, a cerumenolytic solution.
3-5 drops of the product are instilled and the ear basis is then massaged
to favour the direct drug-ectoparasite contact.
A few minutes later the excess product is removed by slightly tamponing
with absorbent cotton.
Four treatments 3 days apart are applied, or as directed by the
veterinarian.
STORAGE
At 15-25o C, protected from light.
PACKAGING
Dropper bottle of 20 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

NEOBACITRACIN
EXTERNAL POWDER

COMPOSITION
Neomycin
1%
Bacitracin
0.4%
Excipient to stimulate tissular regeneration
PHARMACOTHERAPEUTIC ACTIVITY
Due to the two antibiotics, the product has a broad spectrum including
Gram-positive and -negative germs. It has a calmative and a dehydrating
action, and it stimulates healing. It does not diminish phagocytosis, and its
activity is not reduced in contact with the plasm, purulent collections or
cellular detriti. The local tolerance is good, sensitisations being very rare.
INDICATIONS
All species: Topical treatments of infected sutured or unsutured postoperatory wounds, furuncles, incised abscesses, etc.
ADMINISTRATION AND DOSAGE
Accidental, open wounds: The local mechanical cleansing is followed by
thinly powdering the affected area once or several times a day during the
first days, and then 2-3 days apart until recovery.
Sutured wounds (rumenotomies, ovariotomies, ungular operations etc.):
The wound walls and edges are powdered, and the wound is then sutured
with a resorbable or unresorbable thread depending on the case.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Bottle of 50-500 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

NEOHEXIDIN
EXTERNAL POWDER

COMPOSITION
Neomycin
2%
Chlorhexidine
2%
Excipient for tissular regeneration stimulation
PHARMACOTHERAPEUTIC ACTIVITY
The product has a very broad antimicrobial spectrum acting against Gramnegative and -positive bacteria. It is antibacterial and antiseptic due to
both components and to chlorhexidine respectively; it reduces the
diseased tissues turgescence and stimulates healing.
INDICATIONS
All species: Treatment of cutaneous, muscular and podal wounds, and the
prophylaxis of sutured or unsutured wounds (tumoral ablation, male
castrations, rumenotomies, ovariotomies, various surgeries on the hooves
and ungulae).
ADMINISTRATION AND DOSAGE
Accidental, open wounds: The local mechanical cleansing is followed by
thinly powdering the affected area daily during the first 24-72 hours, and
then 2-3 days apart until recovery.
Sutured wounds (rumenotomies, ovariotomies, ungular operations etc.):
The wound walls and edges are thinly powdered, and the wound is then
sutured with a resorbable or unresorbable thread depending on the case
and on the veterinarians directions.
The dressing of the dressed wounds will be changed at 4 days of
interval.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Bottle of 50-500 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

NEO - MINE - VIT P


PREMIX

COMPOSITION
1 gram contains:
Neomycin (as sulphate)
50 mg
Oxytetracycline (as hydrochloride)
50 mg
Hidro- and liposoluble vitamins (A, D3, E, K3, B1, B2, B3, B5, B6, B9, B12, C)
Mineral salts (iron, zinc, copper, magnesium and sodium sulphate,
potassium iodide)
PHARMACOTHERAPEUTIC ACTIVITY
The product is bacteriostatic and -cidal being active against Gram-positive
(Staphylococcus aureus, Streptococcus spp.) and Gram-negative germs
(Escherichia coli, Salmonella spp., Campylobacter spp., Pseudomonas
aeruginosa, Pasteurella spp., Proteus spp., Shigella spp.). The hydro- and
liposoluble vitamins and the mineral salts association increases the
product role in deficiencies and metabolic disorders due to its completing
the nutritional deficit and increasing the body resistance to infections and
stress.
INDICATIONS
Suckling and young pigs, calves, lambs, young sheep, poultry: Prevention
and treatment of neomycin- and oxytetracycline-sensitive germs induced
digestive and respiratory infections.
ADMINISTRATION AND DOSAGE
A 20% aqueous solution is prepared extempore, and orally and
individually administered.
The treatment will be applied for 3-5 days until the symptoms remittal, but
no longer than 7 days.
Preventively: 1-2 kg/t of feed.
Diseased and clinically healthy suckling pigs: 2.5-3 ml, twice a day.
Young pigs: 5-10 ml, twice a day.
Calves: 5 g dissolved in 250 ml of infused herbal plants, twice a day.
Lambs, young sheep: 5-10 ml, twice a day.
Poultry: 2-3 kg/t of feed.
CONTRAINDICATIONS
Renal insufficiencies.
SIDE EFFECTS
The use of tetracyclines during the dental growth may cause
discolouration.
PRECAUTIONS
It should be thoroughly mixed with the feed before administration.
It will not be administered simultaneoulsy with cefalosporins, tylosin,
chloramphenicol and penicillins.
WITHDRAWAL TIME
Meat: 7 days since the last administration.
STORAGE
At 15-25o C, protected from humidity.
PACKAGING
Sachet of 100 or 500 g, or bag of 1 or 5 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

NEOMYCIN SULPHATE 10%


SOLUBLE POWDER

COMPOSITION
Neomycin (as sulphate) 10 %
PHARMACOTHERAPEUTIC ACTIVITY
Neomycin is a bactericidal antibiotic acting against the most important
pathogenic intestinal Gram-negative germs (Escherichia coli, Salmonella
spp., Proteus spp., Klebsiella spp., Shigella spp., Brucella abortus,
Staphylococcus albus). It has no significant activity against viruses,
protozoa and fungi. It acts in the entire digestive tract and remains active
in the intestines in the presence of feed, digestive ferments, pus, necrosed
tissues and at various pHs; in ruminants, it does not destroy the stomachal
flora. It is not absorbed through the skin or gastrointestinal mucosa (3%)
being applied with remarkable results in the oral and topical therapeutics.
INDICATIONS
Cows, calves, horses, sheep, pigs, goats, poultry (hens, turkey cocks,
ducks), dogs, cats, mink: Prophylaxy and treatment of bacterial enterites.
ADMINISTRATION AND DOSAGE
Cows, calves, horses, sheep, goat, pigs, poultry, dogs, cats, mink: 70-210
mg of product (7-21 mg of active ingredient)/kg of body weight for 7-10 days.
Drinking water administration: The animals weight is evaluated in kg,
and the requirements for a day are calculated and then added to the
water estimated for a 12-24 hours consumption:
Preventively: The product (g) = number of kg x 0.011.
Prophylactically: The product (g) = number of kg x 0.03.
Feed administration: 1 sachet (100 g of powder/100 kg of feed).
Broiler chickens, layer hens, turkey cocks: 170-210 mg of the product (7-21
mg of active ingredient)/kg of body weight for 3-5 days.
Drinking water administration
Preventively: The product = kg of body weight x 0.07.
Prophylactically: The product = kg of body weight x 0.21.
Feed administration
Preventively: 1 kg of the product/t of feed.
Prophylactically: 2 kg of the product/t of feed.
CONTRAINDICATIONS
Humans.
WITHDRAWAL TIME
Baby beef: 30 days since the last administration.
Beef: 7 days since the last administration.
Sheep: 20 days since the last administration.
Pork: 3 days since the last administration.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Sachet of 100 or 500 g, or bag of 1 or 5 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

NEOTYL
OINTMENT

COMPOSITION
Tylosin base

2.5 g

Neomycin base

1.0 g

Hydrocortisone acetate

0.1 g

Retinol acetate
Excipient

100,000 IU
up to 100 g

PHARMACOTHERAPEUTIC ACTIVITY
The product is a combination of two antibiotics (neomycin and tylosin) of
broad antibacterial spectrum acting against several Gram-positive and negative germs. It has a high penetration ability, and it persists in the
galactophorus ducts. The simultaneous administration of hydrocortisone
acetate reduces the infectious processes-associated inflammatory
reaction. Concomitantly, the retinol acetate ensures the good functioning
and the regeneration of the epithelial tissues.
INDICATIONS
Small and large ruminants: Treatment of acute, subacute and chronic
forms of neomycin- and tylosin-sensitive germs induced mastites.
ADMINISTRATION AND DOSAGE
Intramammary administration after the thorough milking, washing and
disinfecting.
Acute mastites: 10 g for each affected quarter (2-3 administrations 12-24
hours apart).
Chronic mastites: 15-20 g for each affected quarter, with repetition at 24
hours of interval until the symptoms disappear (usually, 2-3
administrations are needed for stubborn forms).
STORAGE
At 2-8o C, protected from light.
PACKAGING
Tube of 20 or 40 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OCULIN N
OPHTHALMIC OINTMENT

COMPOSITION
Neomycin sulphate
0.5 g
Hydrocortisone acetate
0.5 g
Lidocaine hydrochlorhide
1g
Excipient
up to 100 g
PHARMACOTHERAPEUTIC ACTIVITY
The product associates the effects of neomycin, a broad spectrum
antibiotic with the local anti-inflammatory and analgesic ones of
hydrocortisone and lidocaine.
INDICATIONS
All animals species: Conjunctivites, allergic and nonspecific keratites,
nonsuppurative blepharites.
ADMINISTRATION AND DOSAGE
2-4 times a day in the conjunctival sac for 3-7 days depending on the
condition type and severity.
CONTRAINDICATIONS
Tuberculous and mycotic ocular infections, corneal ulcerations and
wounds.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Tube of 20 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OPTI - CLOR
OPHTHALMIC SOLUTION

COMPOSITION
Chloramphenicol
1g
Boric acid
1.6 g
Ophthalmic excipient up to 100 g
PHARMACOTHERAPEUTIC ACTIVITY
Chloramphenicol inhibits the microbial proteins synthesis. It fixates on subunit
50 S of the bacterial ribosomes 70 S, stopping the peptid chains formation.
The binding to the specific receptor protein on the ribosomes is competitively
hindered by clindamycin, lincomycin and erythromycin. The product is very
active against a number of Gram-positive and -negative germs, of which
Escherichia coli, Staphylococcus aureus and Streptococcus haemolyticus
are the ones involved in most ophthalmic conditions, and very sensitive to
chloramphenicol.
INDICATIONS
Treatment
of
trachoma,
granular
conjunctivitis,
epidemic
keratoconjunctivitis, inclusion conjunctivitis or other superficial ocular
infections induced by chloramphenicol-sensitive germs.
ADMINISTRATION AND DOSAGE
Instillations of 2-3 drops into the conjunctival sac, 3 times a day for 5-7
days.
CONTRAINDICATIONS
Chloramphenicol-sensitive animals.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 7.5 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OTOSTATIC
OTIC OINTMENT

COMPOSITION
Nystatin
1g
Neomycin (as sulphate)
0.4 g
Bacitracin
1.5 g
Hydrocortisone acetate
1g
Excipient
up to 100 g
PHARMACOTHERAPEUTIC ACTIVITY
Nystatin is a fungistatic and -cidal antibiotic active against Candida
albicans, Coccidioides immitis, Cryptococcus neoformans, Histoplasma
capsulatum, some blastomycetes and Sporotrichum. Neomycin is an
antibiotic active against a number of Gram-positive and -negative germs
(Staphylococcus aureus, Streptococcus pneumoniae and pyogenes,
Escherichia coli, Klebsiella spp., Haemophilus influenzae, Salmonella
spp.). Bacitracin is a bactericidal antibiotic active against the Gramnegative germs (the penicillin-resistant staphylococci included). It is less
active against Actinomyces and Fusobacterium. Hydrocortisone acetate is
a topical corticoid having anti-inflammatory, -pruriginous and -allergic
activities. It normalises the keratinisation process.
INDICATIONS
Dogs, cats: External otitis induced by germs sensitive to the product
components.
ADMINISTRATION
The external auditory meatus should be first cleansed with OTTO-CLEANS.
The affected area is then thinly applied with the product 2-3 times a day
with a slight ear massage.
An alternative treatment with OTOSTATIC and MITE EMULSION for 1 day each
is recommended in case of otites of mixed i.e. bacterial/fungal/parasitic
aetiology.
CONTRAINDICATIONS
Sensitivity to any of the product components.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 7.5 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OTOSTOP N
SUSPENSION

COMPOSITION
Neomycin sulphate
Nystatin
Hydrocortisone
acetate
Oily excipient

0.4 g
0.5 g
0.1 g

up to 100
ml
PHARMACOTHERAPEUTIC ACTIVITY
The product associates neomycin, a broad spectrum bactericidal antibiotic
and an antifungal. Through the hydrocortisone acetate, it has an antiinflammatory action. The excipient ensures a good cutaneous penetration.
INDICATIONS
Dogs: Bacterial, parasitic and fungal auricular conditions; external ear
conditions whose aetiological agent is often unprecisely defined by the
diagnosis.
ADMINISTRATION AND DOSAGE
The external auditory meatus is first cleansed with OTTO-CLEANS, and then
instilled with 4-5 drops of the product. The ear basis is slightly massaged
for a few minutes. The treatment is applied daily for 3-5 days. Both ears
are recommended to be treated.
CONTRAINDICATIONS
Cats.
PRECAUTIONS
The bottle should be vigorously agitated before use.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Dropper bottle of 20 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OTTO - CLEANS
CERUMENOLYTIC SOLUTION

COMPOSITION
Salicylic acid 2 %
PHARMACOTHERAPEUTIC ACTIVITY
The salicylic acid is keratolytic and -plastic, weakly antiseptic and slightly
caustic.
INDICATIONS
Dogs, cats: Cleansing of the external auditory meatus in otites of various
aetiology.
ADMINISTRATION
2-3 times a day or as directed by the veterinarian until the clinical signs
remission.
PRECAUTIONS
Strictly for external use.
The contact with the eyes will be avoided.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Dropper bottle of 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OVIZOL 300
GELATINOUS BOLUSES

COMPOSITION
One bolus contains:
Albendazole
300 mg
PHARMACOTHERAPEUTIC ACTIVITY
Albendazole is a broad spectrum anthelmintic against gastrointestinal and
pulmonary nematodes (adults, larvae, eggs), Moniezia spp. and some
trematodes (Fasciola hepatica and Dicrocoelium lanceolatum).
INDICATIONS
Sheep, goats: Treatment of gastrointestinal nematodes, dictyocaulosis,
protostrongylosis, monieziosis, fasciolosis and dicrocoeliosis.
ADMINISTRATION AND DOSAGE
Adult sheep and goats weighing 35-40 kg: A gelatinous bolus of 300 mg
of active ingredient at the tongue basis; its deglutition should be carefully
watched for.
Gastrointestinal and pulmonary nematodes, monieziosis, fasciolosis
treatment: A single bolus.
Dicrocoeliosis treatment: 2 gelatinous boluses of 300 mg of active
ingredient/animal; in this case, however, animals within the first 3 months
of gestation should not be treated.
WITHDRAWAL TIME
Meat: 10 days since the treatment.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box with 5 blister foils x 6 boluses or 100 blister foils x 6 boluses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OXICOR 5%
INJECTABLE SOLUTION

COMPOSITION
Oxytetracycline hydrochloride
5g
Hydrocortisone acetate
0.3 g
Excipient
up to 100 ml
PHARMACOTHERAPEUTIC ACTIVITY
A single administration of the product ensures a complete antibacterial
activity for 48 hours. The product has a broad spectrum of activity: Grampositive germs (Staphylococcus, Streptococcus, Corynebacterium), and
Gram-negative ones (Escherichia coli, Pasteurella, Salmonella, Brucella) with
the exception of Pseudomonas, Klebsiella, Proteus. The antibacterial
spectrum also includes spirochaetes, leptospiras, some rickettsias,
mycoplasmas (Mycoplasma hyopneumoniae). Oxytetracycline, its active
ingredient, rapidly diffuses into the tissues and humors, crosses the placenta
and serosae, being mainly and actively excreted through the kidneys and
bile. The simultaneous administration of hydrocortisone acetate reduces the
inflammatory reaction associated with infectious processes, and increases
the product tolerance.
INDICATIONS
Cattle, horses, pigs, sheep, goats, canines, felines: Treatment of the
pulmonary, digestive, uro-genital and local infections caused by
oxytetracycline-sensitive bacteria.
ADMINISTRATION AND DOSAGE
Deeply intramuscularly at 48 hours of interval as follows:
Adult horses, cattle, pigs: 10 ml/100 kg of body weight.
Adult sheep, goats, canines, felines: 1 ml/10 kg of body weight.
Young pigs, calves, lambs: 2 ml/10 kg of body weight.
PRECAUTIONS
Doses higher than 20 and 5-10 ml for large and for small animals
respectively will be administered at separate sites.
WITHDRAWAL TIME
Meat: 7 days since the last administration.
Sheep milk: 48 hours since the last administration.
Cow milk: 60 hours since the last administration.
STORAGE
At 8-15oC, protected from light. In time, the oxytetracycline solution colour
may darken, the antibiotic maintaining however its efficacy.
PACKAGING
Brown glass bottle of 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OXIPAN
OINTMENT

COMPOSITION
Oxytetracycline
30 mg
-chymotrypsine
(350 U/mg) 1 U
Lipophilic ointment base
up to 1 g
PHARMACOTHERAPEUTIC ACTIVITY
Oxytetracycline is a broad spectrum bacteriostatic antibiotic active against
Gram-positive (streptococci, staphylococci) and Gram-negative germs
(colibacilli, pasteurellas). -chymotrypsine intervenes in the suppurativenecrotic processes destroying the mortified tissues, neutralises a number
of microbial toxins, and stimulates phagocytosis.
INDICATIONS
Sheep: Treatment of paronychia.
All species: Treatment of tegumental pyogenic infections.
ADMINISTRATION AND DOSAGE
Locally, as a thin film applied 2-3 times a day for several days, or as
directed by the veterinarian.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Tube of 20 or 40 g, or plastic box of 50-1000 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OXIRET 20%
INJECTABLE SOLUTION

COMPOSITION
Oxytetracycline hydrochloride
20 %
PHARMACOTHERAPEUTIC ACTIVITY
A single administration of the product ensures a complete antibacterial
activity for 72 hours. The product has a broad activity spectrum: Grampositive germs (Staphylococcus, Streptococcus, Corynebacterium), Gramnegative ones (Escherichia coli, Pasteurella, Salmonella, Brucella). The
antibacterial spectrum also includes spirochaetes, leptospiras, some
rickettsiae, mycoplasmas (Mycoplasma hyopneumoniae). Oxytetracycline,
its active component, spreads rapidly into the tissues and humors, crosses
the placenta and the serosae. It is mainly excreted through the kidneys
and bile under a biologically active form.
INDICATIONS
Cattle, pigs, sheep, goats: Treatment of the pulmonary, digestive, urogenital and local infections induced by oxytetracycline-sensitive bacteria.
ADMINISTRATION AND DOSAGE
Deeply intramuscularly at 20 mg/kg of body weight (1 ml /10 kg of body
weight) at 72 hours of interval. In severe cases, the dose may be repeated
after 3-5 days.
CONTRAINDICATIONS
Horses, canines and felines.
Hypersensitivity to tetracyclines, renal and hepatic insufficiencies.
PRECAUTIONS
One administration will not exceed 20, 10 and 5 ml for cattle, pigs, and
sheep and goats respectively.
WITHDRAWAL TIME
Meat: 21 days since the last administration.
Milk: 7 days since the last administration.
STORAGE
At 8-15oC, protected from light. In time, the solution may alter its colour,
the product maintaining however its efficacy.
PACKAGING
Brown glass bottle 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OXYTETRACYCLINE
SOLUBLE POWDER

COMPOSITION
1 gram contains:
Oxytetracycline (as hydrochloride)
980 mg
PHARMACOTHERAPEUTIC ACTIVITY
Oxytetracycline is an antibiotic bacteriostatic against Gram-positive
bacteria (Actinomyces spp., Bacillus anthracis, Clostridium perfringens,
Clostridium tetani, Listeria monocytogenes, Nocardia spp.) and Gramnegative ones (Bordetella spp., Brucella spp., Bartonella spp.,
Haemophilus spp., Pasteurella multocida, Shigella spp., Yersinia pestis),
mycoplasmas, chlamydias, rickettsiae and protozoa. It blocks the proteinic
synthesis in the bacterial cell.
INDICATIONS
Poultry: Fowl plague, pullorum disease, infectious coryza, infectious
sinusitis, nonspecific diarrhoea, mycoplasmosis, staphylococcal arthritis,
yersiniosis, coliform septicaemia.
Pigs: Enzootic pneumonia, enterites, arthrites, erysipelas.
Calves: Pneumonias, enterites, arthrites, diphtheria, omphalites.
Foals, lambs: Enterites, respiratory infections, omphalites, arthrites.
ADMINISTRATION AND DOSAGE
Poultry: 20-40 g/100 l of drinking water, or 200-400 g/t of feed for 5-7
days.
Calves, piglets, foals, lambs: 10-20 mg/kg of body weight/day, in two
portions, for 4-7 days.
Adults: 5 mg/kg of body weight.
SIDE EFFECTS
During osteogenesis, tetracyclines may turn teeth yellow.
Occasionally, ruminants may exhibit transient gastrointestinal disorders.
REMARKS
The treatments are associated with vitamins B complex, brewers yeast.
WITHDRAWAL TIME
Meat: 10 days since the last administration.
STORAGE
At 8-15o C, protected from light and humidity.
PACKAGING
Sachet of 100 g, or bag of 1 or 5 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OXYTETRACYCLINE 10%
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Oxytetracycline (as hydrochloride)
100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Oxytetracycline is a bacteriostatic antibiotic active against Gram-positive
and
-negative bacteria (Escherichia coli, Pasteurella spp., Salmonella
spp., Brucella spp., Streptococcus spp., Clostridium spp., Haemophilus
spp., Corynebacterium spp., Bacillus anthracis, Staphylococcus spp.,
Rickettsia spp., Mycoplasma spp., Spirochaeta spp., Actinomyces spp.). It
inhibits the proteinic synthesis in the bacterial cell. At high antibiotic
concentrations it is bactericidal. Upon the parenteral administration, it is
very quickly distributed into the blood and tissues.
INDICATIONS
Cattle: Actinobacillosis, foot rot, pneumonias, pasteurellosis, mastites,
metrites.
Sheep, goats: Foot rot.
Pigs: Enterites, erysipelas, pneumonias, the mastitis-metritis-agalactia
syndrome.
Cats, dogs: Respiratory, uro-genital and gastrointestinal infections,
septicaemias.
ADMINISTRATION AND DOSAGE
Daily for 3-5 days, slowly by the intravenous or intramuscular route.
Cattle: 4 ml/100 kg of body weight.
Sheep, goats, pigs: 2-4 ml/ 50 kg of body weight.
Dogs, cats: 1ml/10 kg body weight, by the intramuscular route.
CONTRAINDICATIONS
Tetracyclines-allergic animals, or those with renal and hepatic
insufficiencies.
SIDE EFFECTS
Gastrointestinal dysfunctions caused by the antibiotic action on the
intestinal flora.
During osteogenesis, tetracyclines may turn teeth yellow.
The reactions at the inoculation site are transient, and occasional.
PRECAUTIONS
The intravenous inoculation should be slow.
The intravenous inoculation is not recommended in dogs and cats.
WITHDRAWAL TIME
Meat: 7 days since the last administration.
Milk: 3 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 20, 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OXYTETRACYCLINE 20%
SLOW RELEASE INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Oxytetracycline (as hydrochloride)
100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Oxytetracycline is a bacteriostatic antibiotic active against Gram-positive
and
-negative bacteria (Escherichia coli, Pasteurella spp., Salmonella
spp., Brucella spp., Streptococcus spp., Clostridium spp., Haemophilus
spp., Corynebacterium spp., Bacillus anthracis, Staphylococcus spp.,
Rickettsia spp., Mycoplasma spp., Spirochaeta spp., Actinomyces spp.). It
inhibits the proteinic synthesis in the bacterial cell. At high antibiotic
concentrations it is bactericidal.
INDICATIONS
Cattle: Actinobacillosis, foot rot, pneumonias, pasteurellosis, mastites,
metrites.
Sheep, goats: Foot rot.
Pigs: Enterites, erysipelas, pneumonias, the mastitis-metritis-agalactia
syndrome.
ADMINISTRATION AND DOSAGE
Cattle, sheep, goats, pigs: A single, deep, intramuscular dose of 1 ml/10kg
of live weight.
As a rule, a single treatment is enough for the therapeutic level to persist 3
days; with severe cases, the dose may be repeated after 3-5 days.
CONTRAINDICATIONS
Tetracyclines-allergic animals, or those with renal and hepatic
insufficiencies. Dogs, cats and horses.
SIDE EFFECTS
During osteogenesis, tetracyclines may turn teeth yellow.
The reactions at the inoculation site are transient, and occasional.
PRECAUTIONS
Maximum 20, 5 and 10 ml will be administered to cattle, sheep and pigs
respectively at the same site.
WITHDRAWAL TIME
Meat: 28 days since the last administration.
Milk: 7 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 20, 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OXYTETRACYCLINE 20%
SOLUBLE POWDER
COMPOSITION
1 g contains:
Oxytetracycline (as hydrochloride)

200 mg

PHARMACOTHERAPEUTIC ACTIVITY
Oxytetracycline is an antibiotic bacteriostatic against Gram-positive (Actinomyces spp., Bacillus
anthracis, Clostridium perfringens, Clostridium tetani, Listeria monocytogenes, Nocardia spp.) and
Gram-negative bacteria (Bordetella spp., Brucella spp., Bartonella spp., Haemophilus spp.,
Pasteurella multocida, Shigella spp., Yersinia pestis), mycoplasmas, chlamydias, rickettsiae and
protozoa in animals; also, against Gram-positive and -negative bacteria (Aeromonas salmonicida,
Aeromonas liquefaciens, Pseudomonas fluorescens, Yersinia ruckeri) in fish. Oxytetracycline
blocks the protein synthesis in the bacterial cell.
INDICATIONS
Poultry: Fowl plague, pullorum disease, infectious coryza, infectious sinusitis, infectious synovitis,
nonspecific diarrhoea, mycoplasmosis, staphylococcal arthritis, yersiniosis, coliform septicaemia.
Pigs: Enzootic pneumonia, enterites, arthrites, erysipelas.
Calves: Viral pneumonia, enterites, arthrites, diphtheria, omphalites.
Foals, lambs: Enterites, respiratory infections, omphalites, arthrites.
Dogs: Hepatitis-associated secondary infections.
Cats: Feline infectious anaemia. Control of panleucopenia- and feline influenza-associated
secondary infections.
Rabbits, mink: Bacterial enterites.
Fish: Prophylaxis and treatment of erythrodermatitis, carp air bladder infections, trout
furunculosis.
ADMINISTRATION AND DOSAGE
The medicated solution will be administered immediately upon preparation.
Poultry, pigs: 50-150g/100 l of water, or 0.5-3 kg/t of feed, once a day for 5 days.
Calves, lambs, kids, foals: 1-1.5 g/10 kg of live weight, feed- or drinking water-administered daily
for 5 days.
Dogs, cats, rabbits, mink: 2.5 g/10 kg of live weight divided into two, for 5 days.
Fish: 20- 30 g/100 kg of fish/day in one portion for adults and in 2 portions for young fish. It may
be administered in the feed or in the pool. For young fish, 100 g of thoroughly homogenised
premix as a paste are mixed with 50 kg of pelleted feed. The medicated feed will be stored in
cool, dry rooms for maximum 8 days.
The adult and young fish may be treated for 4-8 days or until the clinical signs are remitted.
SIDE EFFECTS
During osteogenesis, tetracyclines may turn teeth yellow.
Occasionally, ruminants may exhibit transient gastrointestinal disorders.
WITHDRAWAL TIME
Meat: 5 days since the last administration.
Milk: 3 days since the last administration.
Fish meat: 60 days for a water temperature of 12-20oC.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Sachet of 100 or 500 g, or bag of 1, 5 or 20 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

OXYTETRACYCLINE HYDROCHLORIDE
SOLUBLE POWDER

COMPOSITION
Oxytetracycline hydrochlorhide 100%
PHARMACOTHERAPEUTIC ACTIVITY
It has a broad bacteriostatic spectrum: Gram-positive and -negative
germs, some rickettsiae and pathogenic protozoa.
INDICATIONS
Poultry: Mycoplasmosis, fowl plague, turkey sinusitis, colibacillosis,
salmonellosis, secondary infections associated with infectious bronchitis,
coccidiosis and black head.
Pigs: Pulmonary and gastrointestinal conditions, leptospirosis,
erysipelas, pyosepticaemias, mastites, metrites.
Calves, foals, lambs: Pneumopathies, gastroenteropathies, abscesses,
phlegmons, infections of the uro-genital apparatus.
ADMINISTRATION AND DOSAGE
Only orally, in the drinking water or grists (possibly wetted).
Poultry
Infectious coryza: 2g/l of water for 5-7 days.
Mycoplasmosis, sinusites, fowl plague, salmonellosis: 2-3 g/l of water for
5-7 days.
Pigs, calves, foals, lambs
10-20 mg/kg of live weight/day in 2 portions for 4-7 days.
REMARKS
The oxytetracycline treatment is completed with the vitamin B complex.
STORAGE
At 15-20oC, protected from light and humidity.
PACKAGING
Bottle of 100, 200 or 400 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PASTAZOL 25 mg
TABLETS

COMPOSITION
1 tablet contains:
Albendazole (methyl 5n-propionylthio-2-benzimidazole carbamate) 25 mg
PHARMACOTHERAPEUTIC ACTIVITY
Administered orally, the product is through albendazole, its active
component rapidly absorbed and spread to organs and tissues, acting
against adult and larval nematodes, adult flukes and trematodes,
irrespective of the parasites location and of the parasitised animal species.
It is also active against nematode and trematode eggs (ovicidal effect).
INDICATIONS
Pigs: Ascariosis,
metastrongylosis,
oesophagostomosis,
trichocephalosis, trichinellosis.
Poultry:
Taenioses,
ascaridiosis,
heterakidosis,
capillariosis,
amidostomosis.
Carnivores: Taenioses,
toxocarosis,
ancylostomosis,
uncinariosis,
trichocephalosis.
ADMINISTRATION AND DOSAGE
Pigs: Ascariosis, metastrongylosis, oesophagostomosis: A single dose of
5 mg/kg of body weight (1 tablet/5 kg) in well homogenised feed.
Trichocephalosis: 7.5 mg/kg of body weight (1.5 tablet/5 kg) repeated
after 48 hours.
Trichinellosis: 10 mg/kg of body weight (2 tablets/5 kg) for 3
consecutive days, followed by monthly treatments at a single dose of
10 mg/kg of body weight until slaughter.
Poultry:
A single dose of 10 mg/kg of body weight (1 tablet/2.5 kg)
individually or in thoroughly homogenised feed (group treatment).
Carnivores: Taenioses, toxocarosis, ancylostomosis, uncinariosis: 10
mg/kg
of body weight (1 tablet/2.5 kg).
Trichocephalosis: 10 mg/kg of body weight (1 tablet/2.5 kg) with
repetition after 48 hours.
CONTRAINDICATIONS
Pregnant females.
WITHDRAWAL TIME
Meat: 10 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 25, 50, 75 or 100 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PASTAZOL 100 mg
TABLETS

COMPOSITION
1 tablet contains:
Albendazole (methyl 5n-propionylthio-2-benzimidazole carbamate)
100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Administered orally, the product is through albendazole, its active
component rapidly absorbed and spread to organs and tissues, acting
against adult and larval nematodes, adult cestodes and trematodes,
irrespective of the parasites location and of the parasitised animal species. It
is also active against nematode and trematode eggs (ovicidal effect).
INDICATIONS
Pigs: Ascariosis,
metastrongylosis,
oesophagostomosis,
trichocephalosis, trichinellosis.
Poultry:
Taenioses,
ascaridiosis,
heterakidosis,
capillariosis,
amidostomosis.
Carnivores: Taenioses,
toxocarosis,
ancylostomosis,
uncinariosis,
trichocephalosis.
ADMINISTRATION AND DOSAGE
Pigs: Ascariosis, metastrongylosis, oesophagostomosis: A single dose of
5 mg/kg of body weight (1 tablet/20 kg) in well homogenised feeds.
Trichocephalosis: 7.5 mg/kg of body weight (1.5 tablet/20 kg)
repeated after 48 hours.
Trichinellosis: 10 mg/kg of body weight (2 tablets/20 kg) for 3
consecutive days, followed by monthly treatments at a single dose of
10 mg/kg of body weight until slaughter.
Poultry:
A single dose of 10 mg/kg of body weight (1 tablet/10 kg)
individually or in thoroughly homogenised feed (group treatment).
Carnivores: Taenioses, toxocarosis, ancylostomosis, uncinariosis:
10 mg/kg of body weight (1 tablet/10 kg).
Trichocephalosis: 10 mg/kg of body weight (1 tablet/10 kg) with
repetition after 48 hours.
CONTRAINDICATIONS
Pregnant females.
WITHDRAWAL TIME
Meat: 10 days since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 35 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PASTIGAL T
TABLETS

COMPOSITION
Penicillin potassium 0.004 g
Tylosin tartrate
0.020 g
Excipient
up to 0.100 g
PHARMACOTHERAPEUTIC ACTIVITY
Penicillin potassium and tylosin tartrate act simultaneously in destroying
the Gram-positive and -negative germs that induce secondary infections
subsequent to the coccidias-induced intestinal lesions. Tylosin tartrate is
also very active against Mycoplasma gallisepticum and spirochaetes.
INDICATIONS
Preventive and curative treatment of coccidiosis and coccidiosisassociated infections: avian respiratory mycoplasmosis, turkey contagious
sinusitis.
ADMINISTRATION AND DOSAGE
The tablets are administered individually as follows:
Chickens: 1 tablet for 2-3 days.
Adult poultry: 2 tablets for 2-3 days.
Pheasants: 1 tablet for 2 days.
WITHDRAWAL TIME
Meat: 5 days since the last administration.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Bottle of 100 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PEN STREP
INJECTABLE SUSPENSION

COMPOSITION
1 ml contains:
Procaine benzylpenicillin
200,000 IU
Dihydrostreptomycin (as sulphate)
164,000 IU
Excipient
up to 1ml
PHARMACOTHERAPEUTIC ACTIVITY
The two components act synergistically. Procaine benzylpenicillin is an
antibiotic of the penicillin group bactericidal against Gram-positive bacteria
(Bacillus
anthracis,
Clostridium
spp.,
Corynebacterium
spp.,
Fusobacterium spp., Erysipelothrix rhusiopathiae, Pasteurella spp.,
Haemophilus spp. and Brucella spp.). Dihydrostreptomycin is an antibiotic
of the aminoglycosides group bacteriostatic and -cidal against Grampositive and -negative bacteria.
INDICATIONS
Poultry: Mycoplasmosis, coryza, fowl plague, salmonellosis,
colibacillosis, streptococcias, staphylococcias, hepatites, arthrites,
infectious enterites, respiratory infections.
Horses: Salmonella abortions in mares, foal septicaemia, uro-genital and
respiratory
infections,
infectious
enterites,
streptococcias,
staphylococcias.
Cattle, sheep, goats: Leptospirosis, colibacillosis, salmonellosis,
pasteurellosis, infectious enterites, uro-genital and respiratory infections,
Salmonella abortion in ewes.
Pigs: Leptospirosis, colibacillosis, salmonellosis, pasteurellosis,
infectious enterites, uro-genital and respiratory infections, erysipelas.
Dogs, cats: Viral diseases-associated bacterial infections, uro-genital and
respiratory infections, streptococcias, staphylococcias.
ADMINISTRATION AND DOSAGE
Generally, 1 ml/20 kg of body weight administered intramuscularly each
day for 3-5 days.
Horses, cattle: 20-30 ml/day.
Calves, sheep, goats, pigs: 5-10 ml/day.
Piglets, lambs, dogs: 0.5-4 ml/day.
Cats: 0.5-1 ml/day.
CONTRAINDICATIONS
Animals with severe cardiac and renal dysfunctions.
It will not be administered intravenously.
PRECAUTIONS
The bottle should be agitated before use!
WITHDRAWAL TIME
Meat: 7 days since the last administration.
Milk: 48 hours since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Brown glass bottle of 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PET - SPRAY
EXTERNAL ANTIPARASITIC

COMPOSITION
Pyrethrin in a filmogenic excipient.
PHARMACOTHERAPEUTIC ACTIVITY
The product contains a filmogenic excipient allowing the adherence to the
hairs and skin surface thereby improving the persistent effect of the active
ingredient.
INDICATIONS
Dogs, cats: Prevention and control of lice and mites.
It ensures a 2 and a one month protection against the lice and mite
infestation respectively.
USES
The solution is sprayed on the animals fur from a 10-15 cm distance until
a protective film is formed. With the thick furred dogs, the hairs are first
combed aside, the solution is then sprayed contrary to the hair growth
direction, and the animal is allowed to dry in the open air (it will not be
wiped off).
In case of a heavy infestation, the animal is recommended to be
previously cleansed with an antiparasitic shampoo.
100 ml are enough for a 20 kg dog.
CONTRAINDICATIONS
Animals younger than 3 months.
Diseased or convalescent animals.
PRECAUTIONS
The animals eyes and genitalia should be protected.
The spraying should be in the open air.
The product should not be used near a fire source.
There will be no smoking during the product application.
The empty bottle will be disposed of.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 200 or 500 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PHYSIOLOGIC SALINE
INJECTABLE SOLUTION

COMPOSITION
Sodium chloride 9 %
PHARMACOTHERAPEUTIC ACTIVITY
Sodium chloride stimulates the salivary and gastrointestinal secretions,
fluidises the mucosae secretions, contributes to maintaining the osmotic
balance and to the body rehydration, participates in the mineral salts
metabolism.
INDICATIONS
Restoration of the hydroelectrolytic balance in the vomiting-induced
dehydration, facilitation of the acid-base balance maintenance. Also, in
diarrhoea, haemorrhages, intoxications (it favours the body toxins and
toxicants excretion).
ADMINISTRATION AND DOSAGE
Cattle, horses: 500-1500 ml, by the intravenous route.
Pigs, sheep: 200-400 ml, by the intravenous, intramuscular and
subcutaneous routes.
Small animals: 20-100 ml, by the intravenous, intramuscular and
subcutaneous routes.
The treatment may be repeated during the same day.
STORAGE
At 8-5oC, protected from light.
PACKAGING
Bottle of 20, 50, 100, 200 or 400 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PILOCARPINE
INJECTABLE SOLUTION

COMPOSITION
Pilocarpine nitrate 1 %
PHARMACOTHERAPEUTIC ACTIVITY
Pilocarpine is a parasympathomimetic acting similarly with acetylchloline
(a chemical mediator of the parasympathetic nerve); it increases the
salivary, gastrointestinal, lacrimal and bronchial secretions, strengthens
the intestinal movements tonus and amplitude, contracts the uterine
musculature, produces bradycardia and myosis if instilled into the
conjunctival sac.
INDICATIONS
Ruminants, horses: Purgative.
Cattle: Ruminative in overeating-induced indigestions.
Pigs: Vomitive in stomachal indigestions.
Ophthalmology: Prevention of synechiae between the crystalline lens
and the surrounding tissues.
Horses: Hydrops, oedema or laminitis.
ADMINISTRATION AND DOSAGE
Subcutaneously, as follows:
Horses: 0.03-0.2 g (3-20 ml) depending on the case; higher doses will be
fractioned and inoculated at a 1-2 hour interval.
Large ruminants: 0.03-0.05-0.1 g (3-5-10 ml).
Pigs, sheep : 0.01-0.03 (1-3 ml).
Dogs: 0.003-0.005 g (0.3-0.5 ml).
Ocular conditions: Instillations.
CONTRAINDICATIONS
Cardiac and pulmonary conditions, pregnant females.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 5, 10 or 20 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PRAZYTEL
ANTIPARASITIC TABLETS

COMPOSITION
1 tablet contains:
Praziquantel
50 mg
Pyrantel (as pamoate)
144 mg
Excipient
up to 1 tablet
PHARMACOTHERAPEUTIC ACTIVITY
Praziquantel is an anthelmintic active against the evolutional stages of
taenias (Taenidae, Dilepididae, Mesocestoididae, Echinococcus spp.,
Taenia spp., Dipylidium caninum). Pyrantel acts against gastrointestinal
nematodes as a neuromuscular, depolarising and blocking agent that
paralyses the muscles of the parasite. This allows the host a normal
intestinal peristaltism that will lead to the parasite excretion.
INDICATIONS
Dogs, cats: Treatment of infestations induced by Toxacara canis,
Toxocara cati, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma
caninum,
Ancylostoma
tubaeforme,
Echinococcus
granulosus,
Echinococcus multiloculari, Dipylidium caninum, Taenia spp.,
Mesocestoides spp.
ADMINISTRATION AND DOSAGE
A single dose is administered.
5-10 kg dogs: 1 tablet.
Young cats: 1/4 tablet.
Adult cats: 1/2 tablet.
The administration is recommended 3-4 times a year.
No diet is recommended before the treatment.
In the case of Dipylidium caninum reinfestation caused by fleas, the
intermediate host, the fleas will be first removed from both the animal and
the resting places, and the treatment will be then repeated 14 days later.
CONTRAINDICATIONS
Weak animals.
PRECAUTIONS
No overdosage is allowed.
It will be administered with great caution to pregnant females.
It will not be administered together with piperazine-containing
preparations.
It should be kept out of the reach of children.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Bottle of 30, 50 or 100 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PREMIX E-150
PREMIX

COMPOSITION
Vitamin E (tocopherol)
150.00 g
500 IU/g
Vitamin B6 (pyridoxine)
5.00 g
Methionine
200.00 g
Sodium selenite
0.10 g
Lactose
up to 1000.00 g
PHARMACOTHERAPEUTIC ACTIVITY
Vitamin E, a natural antioxidant, protects vitamin A, carotene, unsaturated
fat acids, coenzyme Q. It maintains a high protection level of the cellular
medium against the attack of free radicals. It stimulates the immune
system. Vitamin B6 is a vitamin factor playing the role of a coenzyme in the
metabolism of amino acids. Selenium regulates the detoxification
processes by activating glutathioneperoxidase and regenerating
glutathione. It is present in the signal peptides involved in
immunomodulation. Methionine, an amino acid essential for poultry, is
involved in the methylation processes. Selenomethionine is used in the
body only after its metabolisation to selenocysteine and selenol. Its
metabolic activity is blocked by the deficiency in vitamin B6. The product
formula is based on the metabolic interrelationships between these
elements.
INDICATIONS
For young poultry, in particular, in the:
Prophylaxy and treatment of the diseases induced by vitamin E and
selenium deficiencies, i.e. encephalomalacia, exudative diathesis,
myopathies.
Improvement of the animals performances, increase in the resistance to
diseases, decrease in the stress effects, improvement of the immune
response.
ADMINISTRATION AND DOSAGE
1 g/kg or 1 kg/ton in combined feed, after an intermediate premix, during
the first 2-3 weeks of life and the pre- and post vaccinal periods.
STORAGE
At constant temperature, protected from light and humidity.
PACKAGING
Plastic or aluminium foil sachet of 50-1000 g, or hydrophobic paper sack
of 1-25 kg.
MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PRO - CAL
GROWTH PROMOTING TABLETS

COMPOSITION
1 tablet contains:
Calcium
140-155 mg
Phosphorus
110 mg
70 IU
Vitamin D3
Magnesium sulphate
1 mg
Cobalt gluconate
1 mg
Iron sulphate
1 mg
PHARMACOTHERAPEUTIC ACTIVITY
The product is a complex of calcium and phosphorus salts, vitamin D3 and
other mineral salts that stimulate the normal skeletal growth.
INDICATIONS
Dogs, cats: Growth promoter during the first 14 months of life, or during
the gestation and lactation periods of bitches.
ADMINISTRATION AND DOSAGE
Dogs below 5 kg of live weight: 1 tablet/2.5 kg
Dogs over 5 kg of live weight: 2 tablets/10 kg
Bitches during pregnancy and lactation: 1 tablet/12 kg
Cats below 5 kg of live weight: 1 tablet/2.5 kg
Cats over 5 kg of live weight: -1 tablet
PRECAUTIONS
It should be kept out of the reach of children.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Bottle of 60 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PROLIZ
INJECTABLE SOLUTION

COMPOSITION
Ester isopropyl of (+) chloprostenol, a synthetic structural analogue of the
natural F2 prostaglandin.
PHARMACOTHERAPEUTIC ACTIVITY
Due to the vasoconstriction of the ovary, it has a very strong luteolytic
effect, thereby producing the morphological and functional regression of
the yellow body, followed by the reoccurrence of the oestrum and
ovulation. It also has an ocytocic effect as it stimulates the myometrum
contractions.
INDICATIONS
Prevention and treatment of reproduction dysfunctions and diseases
Cows, heifers: Suboestrum (silent heats), persistent yellow body, ovarian
cysts, placental retention, dystocia, chronic endometrites, pyometrites,
mummified foetus expulsion, abortion induction in undesired gestations,
parturition induction, heats synchronisation.
Mares: Persistent yellow body, post-parturition anoestrum.
Reproduction biotechnology
ADMINISTRATION AND DOSAGE
Prevention and treatment of reproduction dysfunctions and diseases
Cows
Suboestrum, post yellow body diagnosing (two variants):
Inoculation followed by artificial insemination or service upon the
oestrum occurrence; in case there is no oestrum, a second inoculation
is administered 11 days after the first one, followed by artificial
insemination or double and anovulatory service 72 and 96 hours later.
In case no oestrum is detected, two successive inoculations are
administered at 11 days of interval, followed by artificial insemination or
double and anovulatory service 72 and 96 hours later.
Persistent yellow body: A single inoculation induces the oestrum, and the
artificial insemination or service are applied.
Thick walled luteinic ovarian cysts: A single inoculation.
Follicular and thin walled luteinic ovarian cysts: First the luteinisation is
induced with chorionic gonadotrophins, followed by the product
administration 10-17 days later.
Prevention of placental retentions: Inoculation 1-1 hour at the most
after parturition.
Dystocias prevention: Inoculation during parturition.
Chronic endometrites, pyometrites (two variants):
One inoculation, followed by a booster 11 days later, then artificial
insemination or service upon the oestrus.
Prostaglandin association with an oestrogen: SINTOFOLIN on day 0,
PROLIZ on day 4 or 5, with repetition on day 15 or 16, followed by
artificial insemination or service after 72 and 96 hours.

Mummified foetus expulsion: One inoculation during the first gestational


half.
Undesired gestation interruption: Inoculation between day 7 up to 150.
Mares
Persistent yellow body, follicular atrophy: Inoculation during days 4 and 13
of the oestrual cycle for oestrum induction.
Reproduction biotechnology
Cows, heifers
Heats synchronisation (two variants):
Known oestral cycle stage: Inoculation between days 5 and 6.
Unknown oestral cycle stage: Two inoculations 11 days apart, followed
by a booster, artificial insemination or double and anovulatory service
after 72 and 96 hours.
Parturition induction (in special cases):
Gestation shortening, dystocia prevention: The inoculation is maximum
10 days before the expected parturition date.
Prolonged gestations or accidental pathological conditions for foetus
salvage: Inoculation after day 270 of gestation.
Pregnant sows
Parturition induction, farrowings synchronisation and grouping:
Inoculation between days 110 and 113 of gestation, compulsorily within
48 hours before the expected parturition date.
The product is administered only by the intramuscular route as follows:
Cows: 2 ml (0.450 mg of active ingredient).
Mares, sows: 1 ml (0.225 mg of active ingredient).
CONTRAINDICATIONS
Pregnant females (special cases excluded).
It will not be associated with gestagenic hormones (progesteron).
Human therapy.
SIDE EFFECTS
Mares, sows: Unrestleness signs may occur, that disappear within the
hour.
PRECAUTIONS
The administration will be made only by the veterinarian or under his
supervision.
Pregnant women, persons with respiratory conditions are forbidden to
manipulate the product.
The direct contact with the skin will be avoided.
WITHDRAWAL TIME
Meat: 24 hours since administration.
Milk: 6-10 hours since administration.
STORAGE
At 4oC, protected from light.
PACKAGING
Bottle of one or multiple doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PRO - VITE
TABLETS

COMPOSITION
1 tablet contains:
Vitamin A
1200 IU
Vitamin B1
1 mg
1mg
Vitamin B2
Vitamin B5
10 mg
Vitamin B6
0.1 mg
Vitamin B12
1 mcg
Vitamin D3
120 IU
Vitamin E
4 IU
Anhydrous ferrous sulphate
8 mg
Cobalt sulphate
0.068 mg
Manganese sulphate
0.184 mg
Copper sulphate
0.156 mg
Potassium iodide
0.068 mg
Calcium phosphate
340 mg
Magnesium stearate
2.4 mg
Zinc oxide
3 mg
PHARMACOTHERAPEUTIC ACTIVITY
The product is a vitamins and minerals complex in an original formula.
INDICATIONS
Dogs, cats: Palatable feed additive mainly for growing young. It may also
be administered to animals weaken by gestation and suckling, or to
convalescent ones.
ADMINISTRATION AND DOSAGE
Young dogs below 5 kg: 1/2 tablet/day.
Young dogs over 5 kg: 1 tablet/day.
Adult dogs: 1-2 tablets/day.
Cats: 1/2 -1 tablet/day.
PRECAUTIONS
It should be kept out of the reach of children.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Bottle of 50 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PRURITAK
OINTMENT

COMPOSITION
Kanamycin
3-dimethylamino-1-phenyl-1-pyridyl(2)-propane
Undecylenic acid
Dexamethasone
Lipophilic ointment base

1.00 g
0.05 g
2.00 g
0.01 g
up to 100.00
g

PHARMACOTHERAPEUTIC ACTIVITY
Kanamycin is a bactericidal antibiotic acting against many Gram-positive
and
-negative germs, penicillin-resistant staphylococci included. 3dimethylamino-1-phenyl-1-pyridyl-(2)-propane is an antihistaminic, mainly
recommended in allergies. The undecylenic acid is a fungistatic active
particularly against microspores. Dexamethasone is a synthetic
corticosteroid with a rapid anti-allergic and-pyretic action in inflammations,
oedemata and pruritus. The ointment base that has a protective action is
slightly astringent and antiseptic.
INDICATIONS
All species: Local treatment of allergic dermatites, eczemas, secondary
infections.
ADMINISTRATION AND DOSAGE
The affected areas are cleansed and applied with the product twice a day.
The treatment is repeated until a visible improvement is noticed, followed
by a single application a day until the complete recovery or as advised by
the veterinarian.
CONTRAINDICATIONS
Kanamycin-sensitive animals.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Opaque plastic bottle of 50-250 g, or aluminium tube of 20-100 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PYRATEL CD
ANTIPARASITIC SUSPENSION

COMPOSITION
1 ml contains:
Pyrantel (as pamoate)
5 mg
PHARMACOTHERAPEUTIC ACTIVITY
Pyrantel is active against gastrointestinal nematodes (Ancylostoma
caninum, Ancylostoma braziliense, Ancylostoma tubaeforme, Toxocara
cati, Toxocara canis, Toxascaris leonina, Uncinaria stenocephala), acting
as a neuromuscular, depolarising and blocking agent that paralyses the
parasites muscles. This allows the host a normal intestinal peristaltism
leading to the parasite excretion. It is rapidly metabolised and excreted
(35-40%) mostly with the faeces, being more active against the large
intestine parasites. Due to its cholinergic activity, it should not be
associated with parasympathomimetics or organophosphoric compounds.
INDICATIONS
Dogs, cats: Treatment of gastrointestinal nematodes.
ADMINISTRATION AND DOSAGE
Dogs: 1 ml/kg of body weight.
Cats: 4 ml/kg of body weight.
Puppies and kittens younger than 12 weeks: Treatment I is applied
between day 10 (day 1 for kittens) and 14 of life; the subsequent ones
are applied weekly starting with week 2 or 3. Should the infestation
persist, the treatment is recommended to continue 2 weeks apart until
the animal is 12 weeks old.
Dogs and cats aged over 12 weeks: The animals living under satisfactory
hygienic conditions, regular every 3 months treatments are enough; the
monthly treatment is recommended for cats.
Pregnant bitches and cats: The treatment will be applied 2, 4, 6, 8 and 10
weeks after each parturition.
The cats will be treated 2, 4 and 6 weeks after each oestral cycle.
Parasitic infestations: One dose is applied, with repetition 2-3 weeks
later.
PRECAUTIONS
It should not be applied simultaneously with piperazine.
The over- or subdosing will be avoided.
It should be shaken before use!
No dietary measures are necessary.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 30, 100, 500 or 1000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PYRATEL EQ
ANTIPARASITIC PASTE

COMPOSITION
1 ml contains:
Pyrantel (as pamoate)
132 mg
PHARMACOTHERAPEUTIC ACTIVITY
Pyrantel is active against gastrointestinal nematodes (Strongylus vulgaris,
Strongylus edentatus, Strongylus equinus, Oxyurus equi, Parascaris
equorum), acting as a neuromuscular, depolarising and blocking agent
that paralyses the parasites muscles. This allows the host a normal
intestinal peristaltism leading to the parasite excretion. It is rapidly
metabolised and excreted (35-40%) mostly with the faeces, being more
active against the large intestine parasites.
INDICATIONS
Horses: Prophylaxis and treatment of parasitic diseases induced by
gastrointestinal nematodes and ileocaecal cestodes (Anoplocephala).
ADMINISTRATION AND DOSAGE
Orally, with a doser syringe that is introduced as deeply as possible into
the interdental space of the buccal cavity, placing the drug at the tongue
basis. The horses head is lifted for a few seconds immediately post
administration.
Gastrointestinal nematodes: 660 mg /100 kg of live weight, i.e. one
graduation (5 ml)/100 kg of live weight.
Cestodes: Double doses in comparison with those used to control the
gastrointestinal nematodes.
Foals aged 2-8 months: Monthly.
Horses and poneys over 8 months: Every 6 weeks.
Pregnant mares: 1 month before foaling, with repetition 10-14 days post
foaling.
CONTRAINDICATIONS
Weakened animals.
It should not be administered concomitantly with morantel, levamisole,
piperazine, organophosphoric compounds.
PRECAUTIONS
Before the paste administration, care should be taken for the buccal cavity
to be free from any feed.
It is only for veterinary use.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic syringe of 30 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PYRATEL PREMIX
ANTIPARASITIC PREMIX

COMPOSITION
100 g contain:
Pyrantel (as pamoate)
18 g
Excipients
up to 100 g
PHARMACOTHERAPEUTIC ACTIVITY
Pyrantel is active against gastrointestinal nematodes (Ascaris suum,
Oesophagostomum spp., Hyostrongylus spp.), acting as a neuromuscular,
depolarising and blocking agent that paralyses the parasites muscles.
This allows the host a normal intestinal peristaltism leading to the parasite
excretion. It is rapidly metabolised and excreted (35-40%) mostly with the
faeces, being more active against the large intestine parasites. Due to its
cholinergic
activity,
it
should
not
be
associated
with
parasympathomimetics or organophosphoric compounds.
INDICATIONS
Pigs: Prophylaxis and treatment of gastrointestinal nematodes.
Prevention of the Ascaris suum and Oesophagostomum spp. larvae
migration to the lungs and liver of young animals immediately post
weaning and of pregnant females.
ADMINISTRATION AND DOSAGE
Prophylaxis and treatment of Ascaris suum and Oesophagostomum spp.
parasitoses: A single dose of 20 g of premix/100 kg of body weight (8 kg
of premix/t of feed). In case of severe infestations, the treatment will be
repeated 4-6 weeks later.
Prophylaxis and treatment of parasitoses induced by Ascaris suum alone:
2.5 g of premix/100 kg of body weight (1 kg of premix/t of feed) for 3
consecutive days.
Prophylaxis of Oesophagostomum spp. infestation and Ascaris suum
larvae migration to lungs and liver: 2.5 g of premix/100 kg of body weight
(1 kg of premix/t of feed) for 30 consecutive days.
CONTRAINDICATIONS
Hypothreptic animals.
It should not be administered concomitantly with morantel, levamisole,
organophosphoric compounds, diethylcarbamazine, piperazine.
PRECAUTIONS
It is only for veterinary use.
WITHDRAWAL TIME
Meat: 10 weeks since the last administration.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Sachet of 100 or 500 g, or bag of 1, 5 or 20 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

REHIDRASOL
INJECTABLE SOLUTION

COMPOSITION
Mineral salts:
Sodium acetate, sodium chloride, calcium chloride,
potassium chloride, magnesium chloride
Energetic substances: Glucose
Caffeine-sodium benzoate
PHARMACOTHERAPEUTIC ACTIVITY
Due to the mineral salts and water content, the product stimulates the
hydromineral balance and blood volume. The energetic substances
stimulate the vital functions, maintain the metabolic balance, and
disintoxicate the body.
INDICATIONS
Calves, piglets, lambs, foals, etc.: Therapy of the dehydrations induced by
diarrhoeas, bronchopneumonias and transportation, of intoxications,
haemorrhages and shocks; also, restoration of the blood volume and the
metabolic balance.
It is an adjuvant in the antiinfectious medication for enterites of specific
aetiology.
ADMINISTRATION AND DOSAGE
Calves, foals: 300-500 ml (15-25 doses).
Piglets, lambs: 20-60 ml (1-3 doses).
Dogs, cats: 5-10 ml/kg of body weight (0.25-0.5 doses).
The administration route is intravenous, intraperitoneal or preferably
subcutaneous. Care should be taken for the solution temperature to be
close to that of the animal body (the bottle is introduced into a warm water
recipient).
The intravenous inoculation is very slow, drop by drop (perfusions are
preferred). Circa 1/3 of the total amount is recommended to be
intravenously administered, the remaining amount being subcutaneously
inoculated at not more than 60-80 ml at a site with large and medium
sized animals.
In case of severe dehydrations accompanied by metabolic acidosis, the
REHIDRASOL therapy will be preceded by the administration of bicarbonated
solutions.
Depending on the dehydration degree, the product will be readministered
on the same day and/or the following days until the animal recovers.
CONTRAINDICATIONS
Severe metabolic acidosis unaccompanied, beforehand, by the
recommended control measures.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 220 or 500 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

REHIDRAVIT
INJECTABLE SOLUTION

COMPOSITION
Mineral salts: Sodium chloride, sodium acetate, calcium chloride,
potassium chloride, magnesium chloride
Caffeine-sodium benzoate, energetic substances, growth promoters,
vitamins, a plasmatic substituent
PHARMACOTHERAPEUTIC ACTIVITY
Due to the mineral salts and water content, the product facilitates the
restoration of the hydromineral balance and blood volume. The energetic
substances, vitamins and growth promoters stimulate the vital functions,
maintain the metabolic balance, and disintoxicate the body.
INDICATIONS
Calves, piglets, lambs, foals, etc.: Therapy of the dehydrations induced
by diarrhoeas, bronchopneumonias and transportation, of intoxications,
haemorrhages and shocks; also, to restore the blood volume and the
metabolic balance.
Defective young animals: An adjuvant in the antiinfectious medication.
ADMINISTRATION AND DOSAGE
The administration route is intravenous, intraperitoneal or subcutaneous.
Care should be taken for the solution to be well shaken before use.
The intravenous inoculation is very slow, drop by drop (perfusions are
preferred). With medium sized and small animals, it should be
administered at several sites, at not more however than 40-60 ml at one
site.
Depending of the dehydration degree, the product will be readministered
on the same day and/or the following days until the animal recovers.
In case of severe dehydrations accompanied by metabolic acidosis, the
REHIDRAVIT therapy will be preceded by the administration of bicarbonated
solutions for its control.
Calves, foals: 200-400 ml (10-20 doses).
Piglets, lambs: 20-40 ml (1-2 doses).
Dogs, cats: 5 ml/kg of body weight.
CONTRAINDICATIONS
Severe metabolic acidosis unaccompanied, beforehand, by the
recommended control measures.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 200 or 400 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ROSTODERM
OINTMENT

COMPOSITION
Alkaloids, flavonoids, anthracene derivatives, essential oils, tannins,
chlorogenic acid, caffeic acid and allantoin resulted from the maceration
of Chelidoni herba, Calendulae flos, Hyperici herba and Symphyti radix.
Ointment base:
Lanolin
10 %
Vaseline
90 %
PHARMACOTHERAPEUTIC ACTIVITY
The product has a healing, epithelising, antiseptic, anti-inflammatory and
emollient effect. The vegetal components have a soothing effect,
stimulating the tissue recovery in wounds of any nature.
INDICATIONS
Surgical or accidental, sutured or unsutured cutaneous wounds
treatment: It shortens the healing duration of wounds of any nature in all
animal species.
Purulent or atonic burns and wounds.
Papillomatosis: Treatment of the wounds resulted from the surgical
extirpation of papillomas.
Mammary gland cutaneous affections (fissures, crevices) prevention and
treatment: It may be used daily, after milking.
Hoofs or ungulae surgery: Quickened tissual recovery, stimulates the
horny layer growth.
Dehorning: Post-operative treatment.
ADMINISTRATION AND DOSAGE
Open wounds: They are thinly applied, after cleansing, with the product and,
possibly, with a protective dressing. The treatment is repeated daily, until
recovery.
Sutured wounds: A thin layer is applied depending on the case and the
directions of the veterinarian.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Plastic box of 50 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SCABATOX
ANTIPARASITIC CONCENTRATED EMULSIFIABLE SOLUTION

COMPOSITION
Amitraz
125 g/l
INDICATIONS
Cattle, sheep, goats, pigs, dogs: Treatment by dipping or local
applications of scabies, mites and lice.
Animal houses, tools: Spray disinfection.
ADMINISTRATION AND DOSAGE
The solution is prepared upon use, and vigorously agitated.
Cattle (spray): 20 ml/10 l of water (1 part of the product in 500 parts of
water).
Minimum 5 l of solution are necessary for an adult.
Sheep, goats (dip): 1 l/500 l of water (the initial bath). The dipping bath
volume is calculated, clean water is poured and added with the
necessary amount of the solution with thorough mixing. The solution
height in the dipper should be 70 and 90-100 cm for the young and
adults respectively. The animals body should be completely dipped into
the solution for cca 30 seconds, with at least once immersing the
animals head as well.
Lambs may be safely dipped since 3-4 days of age with redipping 3-4
weeks later.
With the young and adults, the dipping may be repeated in case of
heavy infestations after 10-14 days.
When the dipping bath volume drops by 20%, the dipper is replenished
with a replenishment solution (1.5 l/500 l of fresh water).
Pigs (spray): 40 ml/10 l of water (1 part of the product to 250 parts of
water). The treatment is repeated 14 days later. The crusts need not be
removed before the treatment.
Canines: 1 ml/500 ml of water for the local treatment of the affected
areas. The treatment may be repeated once a week for 3-4 weeks.
Houses and tools disinfection: 80 ml/10 l of water.
CONTRAINDICATIONS
Atropine will not be administered (amitraz is not an organophosphoric
compound).
Vomiting will not be induced.
PRECAUTIONS
Protective clothing will be worn during the treatment.
The hands and exposed skin will be thoroughly washed after the
treatment.
In case of dizziness, the physicians advice will be sought.
The recipients will be destroyed once the product is used.
WITHDRAWAL TIME
Pig, goat and cattle meat: 24 hours since the last treatment.
Sheep meat: 7 days since the last treatment.
STORAGE
In well aerated places, protected from open fire as it is inflammable.
PACKAGING
Bottle of 500, 1000 or 5000 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SINGAL 5 mg
TABLETS

COMPOSITION
1 tablet contains:
Albendazole (methyl 5n-propionylthio-2-benzimidazole carbamate) 5 mg
PHARMACOTHERAPEUTIC ACTIVITY
Administered orally, the product is through albendazole, its active
component rapidly absorbed and spread to organs and tissues, acting
against adult and larval nematodes, adult cestodes and trematodes,
irrespective of the parasites location and of the parasitised animal species. It
is also active against nematode and trematodes eggs (ovicidal effect).
INDICATIONS
Curative individual treatments to control syngamosis, ascaridiosis,
capillariosis, heterakidosis, cestodoses and trematodoses.
ADMINISTRATION AND DOSAGE
A single oral dose of one tablet per chicken with clinical signs (syngamosis
in particular) up to 2 tablets per diseased chicken weighing over 100 g.
It may be given to pigeons as well.
STORAGE
At room temperature, protected from light and humidity.
PACKAGING
Bottle of 50 or 100 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SODIUM IODIDE
INJECTABLE SOLUTION

COMPOSITION
Sodium iodide
10 g
Sodium thiosulphate
1g
EDTA-Na2
0.005 g
Deionised water
up to 100 ml
PHARMACOTHERAPEUTIC ACTIVITY
Sodium iodide has an oxidating action in inflammatory foci where, upon
decomposition, it releases iodine. A part of the substance is eliminated by
the respiratory route, having an expectorant and a fluidising action on the
bronchial secretions during pneumonias resolution; it accelerates the
resorption of the exudates in the serous cavities; it permeates the
sclerosed tissues and has a therapeutic effect through iodine and its
derivatives elimination on salivary glands and on genitalia.
INDICATIONS
Treatment of bovine actynobacillosis and -mycosis.
As a resolvent in various chronic inflammatory processes during the
remission of pneumonias.
ADMINISTRATION AND DOSAGE
Intravenously at 5-8 g (50-80 ml/animal) depending on the body weight,
daily for 7-10 days.
The treatment may be associated with 7-8 g of potassium iodide/day in the
drinking water.
The treatment is resumed after 7 days; a third treatment may be applied
depending on the results.
The treatment will be discontinued should incipient phenomena of iodism
mucosal congestion, epiphora, sialorrhea, furfaceous eczema occur.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Ampoule of 20 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

STRESSIN
PREMIX

COMPOSITION
Vitamin A (retinol 500,000 IU/g)
30.00 g
Vitamin
D3
(cholecalciferol
3.00 g
500,000 IU/g)
10.00 g
Vitamin E (tocopherol 500 IU/g)
3.00 g
Vitamin K3 (menadione)
3.00 g
6.00 g
Vitamin B1 (thiamine)
20.00 g
Vitamin B2 (riboflavin)
20.00 g
Calcium pantothenate
4.00 g
Nicotinamide
0.50 g
Vitamin B6 (pyridoxine)
0.03 g
Folic acid
25.00 g
Vitamin B12 (cyanocobalamin)
up to 1000.00 g
Vitamin C
Starch
PHARMACOTHERAPEUTIC ACTIVITY
Polyvitamin association of complex metabolic activities. The hydrosoluble vitamins
are involved in the good functioning of the enzymatic systems by intervening in the
metabolism of proteins, carbohydrates and lipids; additionally, the vitamin B complex
plays, together with the sodium ion, an important role in ensuring the appetite of
poultry. Vitamin C (ascorbic acid) regulates the oxidoreducing processes and
increases the vascular permeability. Vitamins A and E ensure the membranes
integrity, by favouring the nutrients absorption and the reduction of the pathogenic
germs- and coccidia-induced infections.
INDICATIONS
Poultry: Reduction of the stress syndrome effects. Prevention of the secondary
infections associated with the infectious bursal disease, infectious bronchitis,
infectious laryngotracheitis, egg drop syndrome, coryza, coccidiosis, etc.
ADMINISTRATION AND DOSAGE
1-2 kg/t of feed (1-2 g per kg of feed) after an intermediate premix.
STORAGE
At 8-15oC, protected from light and humidity.
PACKAGING
Sachet of aluminium foil of 50-1000 g, or hydrophobic paper sack of 1-25 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SULFASEPT
OINTMENT

COMPOSITION
Sulphanilamide
50.00 mg
Phenylmercuric borate
0.20 mg
Lipophilic ointment base up to 1 g
PHARMACOTHERAPEUTIC ACTIVITY
Sulphanilamide is bacteriostatic against various pathogenic germs
(streptococci, staphylococci, diplococci) replacing the paraaminobenzoic
acid, a factor necessary in the microbial metabolism. The phenylmercuric
borate association strengthens the antimicrobial activity of the product.
INDICATIONS
Prophylaxy and treatment of tegumental pyogenic infections: Wounds,
fistulae, cutaneous ulcers, furunculosis, ocular conditions.
ADMINISTRATION AND DOSAGE
The entire wound surface is thinly applied once or twice a day for 2-4
days, or as directed by the veterinarian.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Plastic box of 50-1000 g, or tube of 20 or 40 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SULFATYL 100
PREMIX

COMPOSITION
Tylosin tartrate
100 g
Sulphatiazole
100 g
Polysaccharide support
up to 1000 g
PHARMACOTHERAPEUTIC ACTIVITY
This association spectrum is effective through the complementary
antiinfectious activity of the two components against most bacteria
including the mycoplasmas responsible for enteropulmonary diseases
frequent in large-scale pig rearing systems.
Mycoplasmas : M. hyopneumoniae, M. hyorhinis.
Gram-positive germs: Staphylococcus spp., Streptococcus spp.,
Erysipelothrix rhusiopathiae.
Gram-negative germs: Campylobacter spp., Escherichia coli, Bordetella
bronchiseptica, Salmonella spp., Pasteurella spp.
Varia: Brachyspira (Serpulina, Treponema) spp., Leptospira spp.
The product is nontoxic.
INDICATIONS
Sows: Control of the mastitis-metritis-agalactia syndrome.
Suckling and young pigs: Respiratory and enteric dysfunctions induced
by SULFATYL 100-sensitive germs.
ADMINISTRATION AND DOSAGE
Sows: 1 kg of premix/t of compound feed (1 g of premix/kg of compound
feed) 15 days before and after parturition.
Sucklers: 1 kg of premix/t of compound feed (1 g of premix/kg of
compound feed) until weaning.
Young pigs: 2 kg of premix/t of compound feed (2 g of premix/kg of
compound feed) 30 days since weaning.
Premixes are made beforehand for a thorough homogenisation.
WITHDRAWAL TIME
Meat: 9 days since the last administration.
STORAGE
At 8-5oC, protected from light and humidity.
PACKAGING
Aluminium foil sachet or plastic bottle of 50-1000 g, or hydrophobic paper
sack of 1-25 kg.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

SUPER KILLER 25 EC
CONCENTRATED INSECTICIDE FOR PROFESSIONAL OPERATORS

COMPOSITION
Cypermethrin
25 %
PHARMACOTHERAPEUTIC ACTIVITY
The product is a pyrethroid insecticide active against ectoparasites mainly
by contact, and by ingestion as well. It is lethal to insect eggs and larvae.
It is also active against the ectoparasites having become resistant to
organic chloride, organic phosphatic or carbamate insecticides.
INDICATIONS
Prevention and control of discomfort generating insects (cockroaches,
mosquitoes, lice, flies, ants, fleas, spiders, moths, wasps, bed bugs, ticks)
in animal plants, industrial buildings, residential sites, hospitals, schools,
hotels, restaurants, food manufacturing and servicing establishments,
chemists shops, laboratories, greenhouses, warehouses, trains, lorries,
ships.
USES
Only the freshly water-diluted and thoroughly homogenised solution will be
used.
Cockroaches, mosquitoes, lice, flies, ants spraying: 15-20 ml of solution
in 4 l of water (0.1 %).
Fleas, spiders, moths, wasps, bed bugs, ticks spraying: 30-35 ml of
solution in 4 l of water (0.2%).
Buildings protective barrier: A uniform layer of cca 100 ml of solution/m2
is applied to a 2-3 m band around the building and to its foundation (cca
1 m high).
Persistence: 6-8 weeks since application, depending on the absorption
degree of the surface.
PRECAUTIONS
It will not be used on electrical equipment.
It will not be used in animal houses.
It will not be used on plants and seeds for human consumption.
The contact with the product through vapours inhalation, spraying,
ingestion will be avoided.
The rivers and lakes contamination will be avoided.
The product is toxic to fish and bees.
Once emptied, the container will be disposed of.
Antidote: Atropine sulphate.
WARRANTY
The manufacturer/distributor guarantees the product quality only for the
original sealed container and efficacy only if used as directed.
STORAGE
In a cold, dry place, protected from fire sources.
PACKAGING
Container of 1 or 5 l.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TETRACYCLINE 100
TABLETS

COMPOSITION
1 tablet contains:
Tetracycline (as hydrochloride) 100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Tetracycline is a broad spectrum antibiotic bacteriostatic against aerobic
and anaerobic Gram-positive and -negative germs, spirochaetes,
mycoplasmas, rickettsias, chlamydias.
It is relatively well absorbed in the gastrointestinal tract, and excreted
mainly via the kidneys.
Tetracycline acts synergistically with streptomycin, chloramphenicol,
sulphonamides, and nitrofurans.
INDICATIONS
Dogs, cats: Treatment of respiratory, uro-genital and gastrointestinal
conditions, mastites, skin infections.
ADMINISTRATION AND DOSAGE
Dogs, cats: 1 tablet/5 kg of live weight every 8-12 hours for 2-4 days.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 50 or 100 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TETRACYCLINE 250
TABLETS

COMPOSITION
1 tablet contains:
Tetracycline (as hydrochloride) 250 mg
PHARMACOTHERAPEUTIC ACTIVITY
Tetracycline is a broad spectrum antibiotic bacteriostatic against aerobic
and anaerobic Gram-positive and -negative germs, spirochaetes,
mycoplasmas, rickettsias, chlamydias.
It is relatively well absorbed in the gastrointestinal tract, and excreted
mainly via the kidneys.
Tetracycline acts synergistically with streptomycin, chloramphenicol,
sulphonamides, and nitrofurans.
INDICATIONS
Dogs, cats: Treatment of respiratory, uro-genital and gastrointestinal
conditions, mastites, skin infections.
ADMINISTRATION AND DOSAGE
Dogs, cats: 1 tablet/12.5 kg of live weight every 8-12 hours for 2-4 days.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Bottle of 50 or 100 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TILOMETRIN
EMULSION OINTMENT

COMPOSITION
Tylosin tartrate
10.0 g
Hydrocortisone acetate
0.5 g
Nystatin
3.5 g
Excipient
up to 100.0 g
PHARMACOTHERAPEUTIC ACTIVITY
The product is antibacterial, antimycotic and anti-inflammatory.
Intrauterinely administered, it covers the surface of the uterus, thus
allowing its active ingredients to act. It is very weakly toxic and does not
irritate the skin or eyes.
INDICATIONS
Curative treatment of acute, subacute and chronic endometrites of
ruminants.
ADMINISTRATION AND DOSAGE
Cows: 40 and 20 ml in acute and in subacute and chronic endometrites
respectively.
Ewes: 10 ml.
If necessary, the treatment may be repeated 3 times at a 24-48 hours
interval.
The bottle should be shaken, before each administration, for
homogenisation.
STORAGE
At 15-25oC, protected from light.
PACKAGING
Plastic bottle of 250, 500 or 1000 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TRICHINOSTOP
INTERNAL POWDER

COMPOSITION
Albendazole 4%
PHARMACOTHERAPEUTIC ACTIVITY
Through albendazole, its active ingredient, the product acts against adult
and larval nematodes, some cestodes and trematodes irrespective of the
parasites localisation or animal species. It is also active against nematode
and trematode eggs. Orally administered, it is rapidly absorbed.
INDICATIONS
Treatment of pig trichinellosis.
ADMINISTRATION AND DOSAGE
In the first ration of compound feed at 10 mg of active ingredient/kg of live
weight (2 g/ 8 kg of live weight) for 3 consecutive days.
Each animal will be observed for the dose consumption.
CONTRAINDICATIONS
Females during the first gestational month.
PRECAUTIONS
Should trichinelloscopy evidence, after the treatment with the product,
Trichinella spiralis cysts, the peptic digestion from the diaphragmatic muscle
(20-30 g) will be compulsorily performed irrespective of the cysts
appearance.
WITHDRAWAL TIME
Meat: 10 days since the last administration.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Aluminium foil sachet or plastic bottle of 50-1000 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TYLAROM 50
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Tylosin tartrate equivalent to 50 mg of tylosin base.
PHARMACOTHERAPEUTIC ACTIVITY
Tylosin is a macrolide antibiotic produced by Streptomyces fradiae and
active against many bacteria including Streptococcus, Bacillus,
Staphylococcus,
Corynebacterium,
Clostridium,
Erysipelothrix,
Campylobacter, Spirochaeta, Mycoplasma, Pasteurella, Chlamydia. In
comparison with tylosin base, the tartrate is very quickly absorbed, upon
the intramuscular administration, with high serum peaks and rather shorter
length of activity. When parenterally administered to pregnant cows,
antibiotic levels higher by 5 times the normal serum levels are found in the
milk, which recommends tylosin for the general treatment of mastitis.
INDICATIONS
Infections of the respiratory and uro-genital apparatus, otites, cellulites,
secondary infections associated with viral diseases or post-surgical
infections.
Treatment of specific diseases: Dysentery and enzootic pneumonia of
swine; metrites, mastites, respiratory infections in cattle; acute forms of
pleuropneumonia and contagious agalactia of sheep and goats;
leptospiroses of small animals (dogs, cats).
ADMINISTRATION AND DOSAGE
Intramuscularly as follows:
Cattle: 5-10 mg/kg of body weight (5-10 ml/50 kg)/day for 3-5 days. Not
more than 10 ml/inoculation site is to be administered.
Pigs: 5-10 mg of active ingredient/kg of body weight (1-2 ml/10 kg)/day
for 3 days. Not more than 5 ml/inoculation site is to be administered.
Sheep, goats:10 mg of active ingredient/kg of body weight (2 ml/10
kg)/day for 5 days. Not more than 5 ml/inoculation site is to be
administered.
Adult hens: 0.20 ml/kg of body weight. A single treatment may often
suffice.
Dogs, cats: 5 mg of active ingredient/kg of body weight (1ml/10 kg)/day
for 3-5 days.
CONTRAINDICATIONS
Chickens, turkeys.
It will not be mixed with other solutions as the active ingredient may
precipitate.
SIDE EFFECTS
A slight pain may occur at the inoculation site.
PRECAUTIONS
Should nodules occur at the site of inoculation, the animals will not be
slaughtered for 21 days.
WITHDRAWAL TIME
Meat: 7 days since the last treatment.
Cow milk: 72 hours since the last treatment.
Sheep and goat milk: 48 hours since the last treatment.
STORAGE o
At 8-15 C, protected from light.
PACKAGING
Glass bottle of 20, 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TYLAROM 200
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Tylosin tartrate equivalent to 200 mg of tylosin base.
PHARMACOTHERAPEUTIC ACTIVITY
Tylosin is a macrolide antibiotic produced by Streptomyces fradiae and
active against many bacteria including Streptococcus, Bacillus,
Staphylococcus,
Corynebacterium,
Clostridium,
Erysipelothrix,
Campylobacter, Spirochaeta, Mycoplasma, Pasteurella, Chlamydia. In
comparison with tylosin base, the tartrate is very quickly absorbed, upon
the intramuscular administration, with high serum peaks and rather shorter
length of activity. When parenterally administered to pregnant cows,
antibiotic levels higher by 5 times the normal serum levels are found in the
milk, which recommends tylosin for the general treatment of mastitis.
INDICATIONS
Infections of the respiratory and uro-genital apparatus, otites, cellulites,
secondary infections associated with viral diseases or post-surgical
infections.
Treatment of specific diseases: Dysentery and enzootic pneumonia of
swine; metrites, mastites, respiratory infections in cattle; acute forms of
pleuropneumonia and contagious agalactia of sheep and goats;
leptospiroses of small animals (dogs, cats).
ADMINISTRATION AND DOSAGE
Intramuscularly as follows:
Cattle: 5-10 mg/kg of body weight (2.5-5 ml/100 kg)/day for 3-5 days. Not
more than 10 ml/inoculation site is to be administered.
Pigs: 5-10 mg of active ingredient/kg of body weight (0.5-1 ml/20 kg)/day
for 3 days. Not more than 5 ml/inoculation site is to be administered.
Sheep, goats: 10 mg of active ingredient/kg of body weight (1 ml/20
kg)/day for 5 days. Not more than 5 ml/inoculation site is to be
administered.
Adult hens: 0.05 ml/kg of body weight. A single treatment may often
suffice.
Dogs, cats: 5 mg of active ingredient/kg of body weight (0.25 ml/10
kg)/day for 3-5 days.
CONTRAINDICATIONS
Chickens, turkeys.
It will not be mixed with other solutions as the active ingredient may
precipitate.
SIDE EFFECTS
A slight pain may occur at the inoculation site.
PRECAUTIONS
Should nodules occur at the site of inoculation, the animals will not be
slaughtered for 21 days.
WITHDRAWAL TIME
Meat: 7 days since the last treatment.
Cow milk: 72 hours since the last treatment.
Sheep and goat milk: 48 hours since the last treatment.
STORAGE o
At 8-15 C, protected from light.
PACKAGING
Bottle of 20, 50 or 100 ml.
MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VAGINAL OXYTETRACYCLINE AND NEOMYCIN SUPPOSITORIES


SUPPOSITORIES

COMPOSITION
Neomycin
0.25 g
Oxytetracycline
0.25 g
PHARMACOTHERAPEUTIC ACTIVITY
Due to the two antibiotics (neomycin and oxytetracycline) association, the
product is highly effective against the pathogenic bacterial flora in the
reproductive organs. Neomycin has a specific action against Grampositive and
-negative germs (colibacilli, salmonellas, shigellae,
klebsiellae) and some Gram-positive cocci. Oxytetracycline is a broad
spectrum antibiotic active against Gram-positive and -negative germs
(streptococci, staphylococci, colibacilli, brucellas, rickettsias, leptospiras,
vibrions, etc.). Due to the foaming nature of the product, the active
ingredients disperse uniformly on the vaginal and uterine walls surfaces
being able to diffuse into tissues and humors.
INDICATIONS
Cows, mares, sows, ewes, nanny goats, carnivores: Prophylaxis and
therapy of puerperal infections: Placental retentions, uterine and vaginal
prolapse, tissual lesions-associated dystocias, surgery on the uterus,
cervicites, acute and chronic metrites and endometrites.
ADMINISTRATION AND DOSAGE
They are introduced into the vagina or uterus as follows:
Large animals: 4-6 suppositories/day.
Medium-sized animals: 2-3 suppositories/day.
Small animals: 1-2 suppositories/day.
The treatment is repeated for 2-3 consecutive days.
WITHDRAWAL TIME
Meat: 6 days since the last administration.
Milk: 3 days since the last administration.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box of 5 blister foils x 6 suppositories or 100 blister foils x 6 suppositories.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VAGINAL OXYTETRACYCLINE SUPPOSITORIES


SUPPOSITORIES

COMPOSITION
Oxytetracycline
0.5 g
PHARMACOTHERAPEUTIC ACTIVITY
Oxytetracycline is a broad spectrum antibiotic active against the
pathogenic Gram-positive and -negative germs in the reproductive organs:
streptococci, staphylococci, colibacilli, brucellas, rickettsias, leptospiras,
vibrions, etc. Due to the foaming nature of the product, the antibiotic
disperses uniformly on the vaginal and uterine walls surfaces being able to
diffuse into tissues and humors.
INDICATIONS
Cows, mares, sows, ewes, nanny goats, carnivores: Prophylaxis and
therapy of puerperal infections: Placental retentions, uterine and vaginal
prolapse, tissual lesions-associated dystocias, surgery on the uterus,
cervicites, acute and chronic metrites and endometrites.
ADMINISTRATION AND DOSAGE
They are introduced into the vagina or uterus as follows:
Large animals: 4-6 suppositories/day.
Medium-sized animals: 2-3 suppositories/day.
Small animals: 1-2 suppositories/day.
The treatment is repeated for 2-3 consecutive days.
WITHDRAWAL TIME
Meat: 6 days since the last administration.
Milk: 3 days since the last administration.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box of 5 blister foils x 6 suppositories or 100 blister foils x 6 suppositories.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VALBAZEN 2.5%
SUSPENSION

COMPOSITION
Albendazole 2.5 %
INDICATIONS
Total spectrum anthelmintic of multiple effects in controlling the following
ovine endoparasites:
Gastrointestinal nematodes: Bunostomum, Chabertia, Cooperia,
Haemonchus,
Nematodirus,
Oesophagostomum,
Ostertagia,
Strongyloides, Trichostrongylus spp.
Lung
nematodes:
Dictyocaulus
filaria,
Mullerius
capillaris,
Protostrongylus rufescens.
Cestodes: Moniezia expansa.
Adult trematodes: Fasciola hepatica.
ADMINISTRATION AND DOSAGE
Orally, using a drench.
Nematodes (5 mg of albendazole/ kg of body weight).
Up to 15 kg of body weight: 2.5 ml.
Over 15 kg of body weight: 2 ml/10 kg of body weight.
Trematodes: 7.5 mg/kg of body weight (3 ml/10 kg of body weight).
At this dose, the product reduces the infestation with adult fasciolas up to
94-99%.
CONTRAINDICATIONS
Gestation month I.
PRECAUTIONS
The can should be shaken before use.
WITHDRAWAL TIME
Meat: 10 days.
STORAGE
At 15-25oC, protected from light and freezing.
PACKAGING
Plastic can of 1 l.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VALBAZEN 10%
SUSPENSION

COMPOSITION
Albendazole 10%
PHARMACOTHERAPEUTIC ACTIVITY
Total spectrum anthelmintic of multiple effects in controlling ovine
endoparasites.
INDICATIONS
Gastrointestinal
nematodes:
Bunostomum,
Chabertia,
Cooperia,
Haemonchus, Nematodirus, Oesophagostomum, Ostertagia, Strongyloides,
Trichostrongylus spp.
Lung nematodes: Dictyocaulus viviparus.
Cestodes: Moniezia spp.
Adult trematodes: Fasciola hepatica, Fasciola gigantica.
ADMINISTRATION AND DOSAGE
Orally, by means of a drench.
Nematodes: 7.5 mg of albendazole/kg of body weight (7.5 ml of
suspension/ 100 kg of body weight).
Trematodes: 10 mg of albendazole/kg of body weight (10 ml of
suspension/ 100 kg of body weight).
CONTRAINDICATIONS
Gestation month I.
PRECAUTIONS
The can should be shaken before use.
WITHDRAWAL TIME
Meat: 10 days since the treatment.
Milk: 24 hours since the treatment.
STORAGE
At 15-25oC, protected from light and freezing.
PACKAGING
Plastic can of 1 and 5 l.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VAMEX
SOLUBLE POWDER

COMPOSITION
Vitamin A (retinol 500,000 IU/g)
Vitamin D3 (cholecalciferol 500
000 IU/g)
Vitamin E (tocopherol 500 IU/g)
Vitamin K3 (menadione)
Vitamin B1 (thiamine)
Vitamin B2 (riboflavin)
Calcium pantothenate
Nicotinamide
Vitamin B6 (pyridoxine)
Vitamin B9
Vitamin B12 (cyanocobalamin)
Vitamin C
Methionine
Sodium selenite
Antioxidant
Lysine
Lactose

6.000 g
0.600 g
2.000 g
0.300 g
0.400 g
0.800 g
2.000 g
4.000 g
0.300 g
0.100 g
0.002 g
5.000 g
4.000 g
0.022 g
5.000 g
2.000 g
up to
1000.000 g

PHARMACOTHERAPEUTIC ACTIVITY
The product prevents and treats metabolic disorders, hypovitaminoses
and avitaminoses. It acts as a growth promoter by increasing the flocks
appetite and vitality. It increases the body resistance to infections,
improves the feed conversion rate, stimulates the egg production and the
birds productivity. It reduces the mortality of the newly hatched offspring
and the transport or vaccination stress-induced side effects.
INDICATIONS
Poultry: Increase in the body resistance during the treatment of infectious
diseases.
ADMINISTRATION AND DOSAGE
During the periods of risk for 3-5 days with repetition at 1 week intervals:
The 1-3 weeks period: 5 g/l of drinking water.
The 4-6 weeks period: 10 g/l of drinking water.
The 7-9 weeks period: 10-15 g/l of drinking water.
Adults, layers: 10-15 g/l of drinking water.
STORAGE
At 15-25oC, protected from light and humidity.
PACKAGING
Aluminium foil sachet of 50-1000 g.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VERMIZOL A 10
ANTIPARASITIC TABLETS

COMPOSITION
1 tablet contains:
Albendazole 10 mg
PHARMACOTHERAPEUTIC ACTIVITY
Albendazole is a broad spectrum anthelmintic active against all forms
(eggs, larvae, adults) of cestodes, trematodes and nematodes. Its toxicity
is reduced, doses 5 times higher than the common therapeutic doses
being tolerated.
INDICATIONS
Poultry: Ascaridia gallinarum, Heterakis gallinae, Capillaria spp.,
Syngamus trachea.
Dogs: Toxocara canis, Ancylostoma spp., Uncinaria spp., Trichocephalus
vulpis.
Cats: Paragonimus spp.
Pigs: Ascaris suum, Metastrongylus spp., Trichocephalus spp.,
Trichinella spiralis, Oesophagostomum spp.
ADMINISTRATION AND DOSAGE
Poultry: 1 tablet/kg of live weight (10 mg of albendazole)/day for 2-3
days.
Carnivores: 1 tablet/kg of live weight (10 mg of albendazole)/day for 2-3
days in cestodoses and nematodoses.
2.5 tablets/kg of live weight (25 mg of albendazole)/day for 3
days in trichocephalosis.
Pigs: 1 tablet/kg of live weight (10 mg of albendazole)/day for 2-3 days in
ascariosis, metastrongylosis, oesophagostomosis, trichocephalosis and
trichinellosis.
CONTRAINDICATIONS
Females during the third period of gestation.
WITHDRAWAL TIME
Meat: 10 days.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Bottle of 100 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VERMIZOL A 50
ANTIPARASITIC TABLETS

COMPOSITION
1 tablet contains:
Albendazole 50 mg
PHARMACOTHERAPEUTIC ACTIVITY
Albendazole is a broad spectrum anthelmintic active against all forms
(eggs, larvae, adults) of cestodes, trematodes and nematodes. Its toxicity
is reduced, doses 5 times higher than the common therapeutic doses
being tolerated.
INDICATIONS
Poultry: Ascaridia gallinarum, Heterakis gallinae, Capillaria spp.,
Syngamus trachea.
Dogs: Toxocara canis, Ancylostoma spp., Uncinaria spp., Trichocephalus
vulpis.
Cats: Paragonimus spp.
Pigs: Ascaris suum, Metastrongylus spp., Trichocephalus spp.,
Trichinella spiralis, Oesophagostomum spp.
ADMINISTRATION AND DOSAGE
Poultry: 1 tablet/5 kg of live weight (50 mg of albendazole)/day for 2-3
days.
Carnivores: 1 tablet/5 kg of live weight (50 mg of albendazole)/day for 23 days in cestodoses and nematodoses.
1 tablet/2 kg of live weight (25 mg of albendazole)/day for 3
days in trichocephalosis.
Pigs: 1 tablet/5 kg of live weight (50 mg of albendazole)/day for 2-3 days
in ascariosis, metastrongylosis, oesophagostomosis, trichocephalosis
and trichinellosis.
CONTRAINDICATIONS
Females during the third period of gestation.
WITHDRAWAL TIME
Meat: 10 days.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Bottle of 50 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VERMIZOL A 100
ANTIPARASITIC TABLETS

COMPOSITION
1 tablet contains:
Albendazole 100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Albendazole is a broad spectrum anthelmintic active against all forms
(eggs, larvae, adults) of cestodes, trematodes and nematodes.
INDICATIONS
Sheep, cattle: Digestive and lung strongylidoses, fasciolosis,
dicrocoeliosis, hydatidosis (echinococcosis), cysticercosis.
Pigs: Ascariosis, metastrongylosis, trichocephalosis, trichinellosis,
oesophagostomosis.
Dogs,
cats:
Toxocarosis,
ancylostomatidosis,
uncinariosis,
trichocephalosis.
ADMINISTRATION AND DOSAGE
Cattle, sheep: 1.5 tablet/10 kg of body weight (15 mg of albendazole/kg of
body weight)/day. In areas where fasciolosis is endemic the treatment is
repeated trimestrially.
Pigs: 1 tablet/10 kg of body weight (10 mg of albendazole/kg of body
weight)/day.
Ascariosis, metastrongylosis, trichocephalosis, oesophagostomosis: The
treatment is administered for 2 consecutive days and repeated 7 days
later.
Trichinellosis control (all pigs):
Treatment I: 3 consecutive days.
Treatments II, III and IV: 2 consecutive days/month.
Treatment V: 1 day/month for 5-6 months.
The treatment is discontinued 3 months at least since the last case of
trichinellosis.
Carnivores: 1 tablet/10 kg of body weight (100 mg of albendazole/kg of
body weight)/day in cestodoses and nematodoses. The treatment is
administered for 2 consecutive days with repetition 7 days later.
CONTRAINDICATIONS
Females during the third period of gestation.
WITHDRAWAL TIME
Meat: 10 days.
STORAGE
At 15-25oC, protected from humidity.
PACKAGING
Bottle of 50 tablets.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VETASED
INJECTABLE SOLUTION
COMPOSITION
1 ml contains:
Ketamine (as hydrochloride)
100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Ketamine is a systemic rapidly acting analgesic used in the dissociated anaesthesia or, in
association with other anaesthetics, in neuroleptanalgesia (associated anaesthesia). It selectively
blocks the association paths and depresses the thalamo-cortical system and subcortical structures
without manifestly influencing the other central nervous system structures. It does not significantly
influence the respiratory centre, the pharyngeal and laryngeal reflexes being thus maintained. It is
metabolised in the liver and excreted via the kidneys thereby the accumulation-based intoxication
being avoided. Anaesthesia sets in immediately and within 8-10 minutes in the case of the
intravenous and intramuscular inoculation respectively. It lasts 15-30 minutes, the complete
awakening being within 30-60 minutes.
INDICATIONS
Short-term anaesthesias (obstinant horses calming down); prevention of the pre-operative, restraint
and transport stress; analgesia and narcosis potentation.
ADMINISTRATION AND DOSAGE
Dogs
Dissociated anaesthesia: 5-20 mg/kg. Initially 5 mg /kg, intravenously, then slow perfusion or
intramuscularly. Useful anaesthetic effect: 15-60 minutes. Total anaesthetic effect: 3-5 hours.
Neuroleptanalgesia: 8-20 mg of ketamine/kg intramuscularly or intravenously; 1-2 mg of
xylazine/kg intramuscularly or intravenously; 0.05-0.1 mg of atropine/kg intramuscularly.
Cats
Dissociated anaesthesia: 15-25 mg/kg intramuscularly. Anaesthetic effect: 15 minutes.
Neuroleptanalgesia: 15-20 mg of ketamine/kg intramuscularly; 0.5 mg of xylazine/kg
subcutaneously; 0.1 mg of atropine/kg intramuscularly.
Horses
Dissociated anaesthesia: 2-5 mg/kg intravenously, or 10-20 mg/kg intramuscularly. Initially 2-3
mg/kg intravenously, then slow perfusion or intramuscular inoculation of up to 10-15 mg/kg.
Useful anaesthetic effect: 20-50 minutes. Total anaesthetic effect: 2-3 hours.
Pigs
Dissociated anaesthesia: 10-40 mg/kg intramuscularly or intravenously. Useful anaesthetic effect:
20-120 minutes. Total anaesthetic effect: 3-6 hours.
Cattle
Dissociated anaesthesia: 2-5 mg/kg intravenously, or 5-10 mg/kg intramuscularly or
intravenously.
Sheep, goats
Dissociated anaesthesia: 15-30 mg/kg intramuscularly or intravenously. Useful anaesthetic effect:
15-60 minutes. Total anaesthetic effect: 1.5-3 hours.
CONTRAINDICATIONS
Animals with renal and hepatic dysfunctions, or with decompensated cardiopathies or glaucoma.
Hypertensive animals.
SIDE EFFECTS
Post inoculation, the body temperature may drop by 1.6oC.
Tachycardia or even respiratory arrest may occur after the intravenous inoculation of horses. It
does not confer neurovegetative protection.
Excitation and cardio-respiratory imbalance may occur in cattle, sheep and goats.
PRECAUTIONS
The animals will be protected, until their complete awakening, from noises and strong light.
STORAGE
o
At 15-25 C, protected from light.
PACKAGING
Brown glass bottle of 10 or 20 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VITAMIN AD3E
ORAL VITAMIN COMPLEX

COMPOSITION
Vitamin A
107 IU
Vitamin D3
106 IU
Vitamin E
4g
Excipient
up to 100 ml
PHARMACOTHERAPEUTIC ACTIVITY
The vitamin AD3E complex contains vitamins that are indispensable to life
and acts as a biostimulator, increasing the epithelia and cell membranes
resistance to pathogenic microorganisms. Vitamin A is the epi- and
endothelial protective factor that prevents infections, increases the body
resistance, stimulates the growth and egg laying. Vitamin D3 is
indispensable for the skeletal and egg shell development, takes part in the
calcium-phosphorus balance regulation, intervenes in the carbohydrates
metabolism leading to the increase in the liver and muscular glycogen.
Vitamin E prevents the oxidation of the body lipids and food fats, and its
activity is related to the amino acids and proteins transport in the body. It
potentiates the vitamin A activity.
INDICATIONS
Prophylaxy and treatment of vitamin deficiencies, rickets and
osteomalacia; also, the improvement of deficient rations.
Increase in the body resistance to infections, improvement of the overall
condition, reduction of the transport stress, improvement of breeding
stocks prolificity.
ADMINISTRATION AND DOSAGE
In the drinking water for 3-5 days at the following doses per animal and
day:
Horses, cattle: 5-7 ml.
Calves, foals, pigs: 1-3 ml.
Piglets, rabbits: 1-2 ml.
Poultry: 2 ml/10 l of water.
CONTRAINDICATIONS
Administered in large doses or for a long time it may induce toxic
phenomena manifested by the skin and mucosae colouration, anaemia,
leucopaenia, spleen and liver hypertrophia.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Brown bottle of 20 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VITAMIN B1

5%
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Thiamine hydrochloride
5%
PHARMACOTHERAPEUTIC ACTIVITY
The vitamin B1 molecule combines in the liver, kidney and heart with
phosphoric acid and specific proteins remains producing active
coenzymes and enzymes that participate in the carbohydrates metabolism
(the pyruvic acid decarboxylation and acetaldehyde formation). The
vitamin B1 deficiency hinders or even interrupts this process resulting in
the pyruvic acid accumulation in the body which leads to a number of
pathological conditions of the nervous system. The thiamine deficiency
also leads to the accumulation, in the body, of -ceto-acids and pentoses
that, in higher concentrations than the physiological ones, produce various
metabolic disorders.
INDICATIONS
Conditions of the nervous system (polyneurites, neurites, pareses,
paralyses), toxic myopathies, myalgias, gastrointestinal atonias (paresis of
the rumen, reticulum and omasum), sulphonamides intoxications, cardiac
oedemata, dermatoses, acetonaemia, infectious diseases, etc.
ADMINISTRATION AND DOSAGE
Subcutaneously, intramuscularly or intravenously as follows:
Large animals: 2-10 ml (100-500 mg of active ingredient).
Medium sized animals: 2-5 ml (100-250 mg of active ingredient).
Dogs: 1-2 ml (50-100 mg of active ingredient).
Cats: 0.5-1 ml (25-50 mg of active ingredient).
Poultry: 0.02-0.05 ml (1-2.5 mg of active ingredient).
The treatment may last 3-4 days or until the symptoms disappear.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Brown bottle of 20 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VITAMIN B1 + B6
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
30 mg
Thiamine hydrochloride (B1)
Pyridoxine hydrochloride (B6)
20 mg
PHARMACOTHERAPEUTIC ACTIVITY
The vitamin B complex, whose most important representatives are
vitamins B1 and B6, has deep metabolical implications. Thiamine (vitamin
B1) intervenes in the carbohydrates metabolism (decarboxylation of the
pyruvic acid and acetaldehyde formation); the vitamin B1 deficiency
hinders or even interrupts this process leading to the pyruvic acid
accumulation in the body, which entails a number of pathological
conditions of the nervous system (polyneurites, pareses, paralyses,
contractions, etc.). Pyridoxine (vitamin B6) participates in the metabolism
of the amino acids (tryptophan in particular) and of lipids, favouring their
synthesis. Vitamins B1 and B6 act synergetically in preventing and
controlling nervous conditions (neurites, polyneurites, pareses, etc); also,
in miopathies, myalgies, gastrointestinal atonias, cardiac oedemata, etc.
INDICATIONS
Vitamin B deficiencies (convalescence, intoxications, malabsorption,
hepatic insufficiency).
Conditions of the nervous system (neurites, polyneurites, pareses,
paralyses).
Paresis of the rumen, reticulum and abomasum, rheumatic conditions,
myopathies, myalgias.
Intoxications, acetonaemias, dermatoses, allergies, cardiac oedemata.
ADMINISTRATION AND DOSAGE
Intramuscularly or subcutaneously as follows:
Large animals: 5-10 ml/day.
Calves, sheep, pigs: 2-5 ml/day.
Dogs, lambs, piglets: 1-2 ml/day.
The administration lasts 3-4 days until the symptoms remission.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 5, 10, 20 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VITAMIN B6 5 %
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Pyridoxine hydrochloride (B6)
50 mg
PHARMACOTHERAPEUTIC ACTIVITY
Pyridoxine, one of the most important vitamin of the vitamin B complex,
intervenes in the proteinic and lipidic metabolism favouring the synthesis
of the unsaturated fatty acids, acting as a coenzyme. It activates the skin
and nervous cells trophicity; also, it is an antianaemic factor.
INDICATIONS
Haematological and dermatological conditions, polyneurites, dystrophias,
convalescence, etc.
ADMINISTRATION AND DOSAGE
Intramuscularly or subcutaneously as follows:
Large animals: 5-20 ml/day.
Calves, sheep, pigs: 2-5 ml/day.
Piglets: 0.2-0.4 ml/day.
The administration lasts 5-10 days until the symptoms remission.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 5, 10, 20 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VITAMIN C 10%
INJECTABLE SOLUTION

COMPOSITION
1 ml contains:
Ascorbic acid 100 mg
PHARMACOTHERAPEUTIC ACTIVITY
Vitamin C (the ascorbic acid) stimulates the tissual oxireduction, has an
antitoxic and -infectious action, contributes to maintaining the bony tissue
integrity, as it favours the calcium fixation. It intervenes in blood clotting,
having a desensitising action as well.
INDICATIONS
Haemorrhagic and toxic conditions, post surgery, and as an adjuvant
treatment in infectious diseases and metabolic disorders.
ADMINISTRATION AND DOSAGE
Intravenously as follows:
Large animals: 5-100 ml (0.5-10 g of ascorbic acid)/day diluted in
physiological saline or glucosed serum; up to 200 ml (20 g of ascorbic
acid)/day may be administered in cows ketonaemia.
Medium sized animals, young large animals: 2-10 ml (0.2-1.0 g)/day.
Carnivores: 0.5-2.5-5.0-10 ml (0.05-0.25-0.5-1.0 g of ascorbic acid)/day
depending on the weight.
Poultry: 0.1-0.5 ml (0.01-0.05 g of ascorbic acid)/day. The treatment
length is 2-4 days.
STORAGE
At 8-15oC, protected from light.
PACKAGING
Bottle of 20, 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

VITAMIN K3
INJECTABLE AND ORAL SOLUTION

COMPOSITION
Vitamin K3
Sodium chloride p.a.
Sodium metabisulphite
Methyl p-hydroxybenzoate
Propyl p-hydroxybenzoate
Distilled water

3.11 g
0.20 g
0.15 g
0.08 g
0.02 g
up to 100 ml

PHARMACOTHERAPEUTIC ACTIVITY
Vitamin K3 is indispensable to the hepatic synthesis of prothrombin, being part of the vitamin group
of antihaemorrhagic activity. It plays an important role in the blood clotting process and acts on
capillary endothelia and fibrinogen. The conditions most important induced by vitamin K3 deficiency
are haemorrhages and hypothrombinaemia. At high doses, vitamin K3 activates the
reticulohistiocytic system, produces diuresis (in the case of the systemic oedemata), stimulates the
liver and bone marrow functions. Generally, the vitamin K3 requirements are covered in most
animals by the feed intake and digestive synthesis. Poultry are an exception to this rule. The
vitamin K3 deficiencies in poultry are evident upon necropsy: intraabdominal, ovarian, cloacal,
intestinal, etc. haemorrhages
.
INDICATIONS
Cattle, sheep, horses, pigs, poultry, dogs, cats: Prevention and treatment of haemorrhages.
Prevention of vitamin K3 deficiency in association with the antimicrobial treatment.
Chickens with haemorrhagic diatheses subsequent to infectious or parasitic diseases, or to
intoxications; young poultry predisposed to haemorrhagic conditions subsequent to chronic
hepatites and enterites.
ADMINISTRATION AND DOSAGE
During-surgeries haemorrhages avoidance
Horses, cattle, sheep, pigs: 1 ml/50 kg of body weight/day by the intravenous or intramuscular
route for 3-4 days before the surgery. The dose is doubled on the morning of the surgery.
Dogs, cats: 0.05-0.2 ml/10 kg of body weight/day by the intramuscular or oral route for 3 days
before the surgery. The dose is doubled on the morning of the surgery.
Haemorrhages prevention and treatment
Horses, cattle, sheep, pigs: 4 ml/100 kg of body weight/day by the slow intravenous or
intramuscular route for 2-3 days, followed by 2 ml/100 kg of body weight/day by the
intramuscular or intravenous route for 8-10 days.
Dogs, cats: 0.2 ml/10 kg of body weight/day by the intramuscular route until the haemorrhages
cease.
Poultry
Preventively: 1 ml of solution is diluted in 15-20 l of water and then administered for 8-10 days.
Curatively: 1 ml of solution is diluted in 6 l of water and then administered for 8-10 days.
STORAGE
o
At 8-15 C, protected from light.
PACKAGING
Brown bottle of 50 or 100 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ALEXIN
FREEZE-DRIED COMPLEMENT

COMPOSITION
Normal guinea-pig serum
1 ml
INDICATIONS
Serological diagnosis by complement fixation.
ADMINISTRATION AND DOSAGE
Each bottle content is reconstituted with 1 ml of distilled water, and used
only on the day it is reconstituted.
The titre is bottle-stated; prior to use, it is retitrated in the laboratory that
uses it, in the presence of the respective elements and in keeping with the
technique used.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of a titre-dependent number of doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

AVISAR
CRYSTAL VIOLET STAINED SALMONELLA PULLORUM ANTIGEN

COMPOSITION
Inactive crystal violet stained suspension of Salmonella pullorum, strain O:
IX, XII1, XII3.
INDICATIONS
Diagnosis of pullorum disease in young adult birds by the rapid haemo- or
seroagglutination test.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Dropper bottle of 10 ml sufficient for 200 tests.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BROVSET
KIT FOR BRUCELLA OVIS INFECTION
DIAGNOSIS BY COMPLEMENT FIXATION

COMPONENTS
Brucella ovis antigen: Heat-obtained extract of a suspension of Brucella
ovis, strain 34-T microbial germs in phenol-added physiological saline.
Brucella ovis positive serum: From rams with field or experimental
Brucella ovis infection.
Brucella ovis negative serum: From normal rams, without Brucella ovis
antibodies.
INDICATIONS
Diagnosis of infectious epididymitis of sheep by complement fixation in
veterinary laboratories.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box with:
Brucella ovis antigen (liquid): 1 bottle x 1-2 ml = 100-200 doses
Brucella ovis positive serum (liquid/freeze-dried): 1 bottle x 1 ml = 10 doses
Brucella ovis negative serum (liquid/freeze-dried): 1 bottle x 1 ml = 10
doses

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BRUCEFIX
KIT FOR BRUCELLOSIS DIAGNOSIS
BY COMPLEMENT FIXATION

COMPONENTS
Noncorpuscular Brucella antigen: Heat-obtained extract of a suspension
of Brucella abortus 99 microbial germs in merthiolate-added
physiological saline, standardised for the complement fixating potential.
Brucella positive serum: From rabbits inoculated with Brucella abortus,
standardised to contain 200 IAU/ml.
Brucella negative serum: From normal cattle, without Brucella antibodies.
INDICATIONS
Diagnosis of brucellosis in cattle and pigs by complement fixation in
veterinary laboratories.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box with:
Noncorpuscular Brucella antigen (liquid/freeze-dried):
1 bottle x 1 ml = 250, 500 or 1000 doses, or
1 bottle x 2 ml = 500, 1000 or 2000 doses
Brucella positive serum (liquid/freeze-dried):
1 bottle x 1 ml = 10-40 doses, or
1 bottle x 2 ml = 20-80 doses
Brucella negative serum (liquid/freeze-dried):
1 bottle x 1 ml = 10 doses, or
1 bottle x 2 ml = 20 doses

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BRUCELINA B
BRUCELLA ALLERGEN FOR CATTLE

COMPOSITION
Specific, purified, nonantigenic protein from Brucella abortus germs in a
liquid preservative.
INDICATIONS
Allergic diagnosis of cattle brucellosis.
ADMINISTRATION AND DOSAGE
0.2 ml inoculated strictly intradermally into the neck side.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 25 or 50 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BRUCELINA P
BRUCELLA ALLERGEN FOR PIGS

COMPOSITION
Specific, purified, nonantigenic protein from Brucella suis germs in a liquid
preservative.
INDICATIONS
Allergic diagnosis of cattle brucellosis.
ADMINISTRATION AND DOSAGE
0.2 ml strictly intradermally into the outer side of the ear pavilion.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 25 or 50 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BRUCEROBEN
KIT FOR BRUCELLOSIS DIAGNOSIS BY
RAPID SEROAGGLUTINATION WITH
ROSE BENGAL STAINED ANTIGEN

COMPONENTS
Phenol- and heat-inactivated, and 1% Rose Bengal solution-stained
Brucella abortus 99 (Weybridge) in a buffered and acidified diluent.
Brucella positive serum: From rabbits immunised with Brucella abortus.
Brucella negative serum: From normal cattle, without Brucella antibodies.
INDICATIONS
Diagnosis of animal brucellosis by the rapid seroagglutination test in
veterinary laboratories.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box with:
Rose Bengal stained Brucella antigen:
1 bottle x 20 ml = 660 doses, or
1 bottle x 50 ml = 1650 doses
Brucella positive serum (liquid/freeze-dried):
1 bottle x 1 ml = 30 doses, or
1 bottle x 2 ml = 60 doses
Brucella negative serum (liquid/freeze-dried):
1 bottle x 1 ml = 30 doses, or
1 bottle x 2 ml = 60 doses

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BRUCEROCAN
KIT FOR CANINE BRUCELLOSIS DIAGNOSIS
BY RAPID SEROAGGLUTINATION

COMPONENTS
Rose Bengal stained Brucella canis antigen
Positive Brucella canis serum
0.2 M solution of 2-mercaptoethanol
INDICATIONS
Diagnosis of canine brucellosis by rapid seroagglutination in veterinary
laboratories.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box with:
Rose Bengal stained Brucella canis antigen:
1 bottle x 4 ml
Positive Brucella canis serum:
1 bottle x 2 ml
2-mercaptoethanol:
1 bottle x 4 ml
Rods for homogenisation: 35 pieces
Reaction slides: 2 pieces

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

BRUCETIL
STAINED BRUCELLA ANTIGEN FOR THE MILK RING TEST

COMPOSITION
Phenol- and heat-inactivated and haematoxylin-stained Brucella abortus
microbial germs in physiological saline.
INDICATIONS
Diagnosis of cow brucellosis by the milk ring test.
The test should be used only with adequate milk samples as in the
directions for use.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 20, 50 or 100 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

CHLAMYDIOFIX
KIT FOR CHLAMYDIOSIS DIAGNOSIS

COMPONENTS
The Chlamydia group antigen
Positive serum
Negative serum
INDICATIONS
Serodiagnosis by complement fixation of animal infections induced by
chlamydial microorganisms.
ADMINISTRATION AND DOSAGE
Antigen: Diluted 2 U in 0.2 ml.
Positive serum: Diluted 4 U in 0.2 ml.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Antigen: Bottle of 10 ml.
Positive serum: Bottle of 1 ml.
Negative serum: Bottle of 1 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ELIBRUCELLA
KIT FOR PIG BRUCELLOSIS DIAGNOSIS

COMPONENTS
Polystyrene plate coated with Brucella suis antigen
Positive control serum (diluted 1/100)
Weakly positive control serum (diluted 1/100)
Negative control serum (diluted 1/100)
Peroxidase labelled anti-porcine F(ab)2 conjugate, freeze-dried
Perhydrol solution in citrate buffer
Chromogen ABTS, concentrated solution
Stop solution, powder
Serum and conjugate diluent
Wash solution, 10 times concentrated
INDICATIONS
Diagnosis of pig trichinellosis by ELISA in veterinary laboratories.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box with reagents for the testing of 40 pig sera.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ELITRICH
KIT FOR PIG TRICHINELLOSIS DIAGNOSIS

COMPONENTS
Polystyrene plate coated with the GP fraction of Trichinella spiralis
antigen
Reference pig positive serum, freeze-dried
Reference pig weakly positive serum, freeze-dried
Reference negative serum, freeze-dried
Peroxidase labelled anti-porcine F(ab)2 conjugate, liquid
Substrate with perhydrol in citrate buffer
Chromogen ABTS, concentrated solution
Stop solution, powder
Serum diluent
Wash solution, 10 times concentrated
INDICATIONS
In vivo diagnosis of pig trichinellosis by ELISA in veterinary laboratories.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box with reagents for the testing of 40 pig sera.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ENZOOTIC BOVINE LEUCOSIS KIT


KIT FOR ENZOOTIC BOVINE LEUCOSIS
SERODIAGNOSIS BY AGAR GEL IMMUNODIFFUSION

COMPONENTS
Enzootic bovine leucosis tissue culture antigen.
Positive serum: From cattle with field or experimental enzootic bovine
leucosis virus infection; it contains specific antibodies to the enzootic
bovine leucosis virus.
Diluent for the kit components rehydration.
INDICATIONS
Serodiagnosis of the enzootic bovine leucosis in cattle herds. It is a useful
tool in the enzootic bovine leucosis control programmes as it detects the
carriers of specific precipitating antibodies.
USES
In keeping with the enclosed Directions for use.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Kit with 250 tests/bottle.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

EQUINE INFECTIOUS ANAEMIA KIT


Kit for equine infectious anaemia
SERODIAGNOSIS BY AGAR GEL IMMUNODIFFUSION

COMPONENTS
Equine infectious anaemia tissue culture antigen (freeze-dried).
Equine infectious anaemia positive serum (freeze-dried): Horse serum
with the equine infectious anaemia virus antibodies.
Diluent for the serum rehydration.
INDICATIONS
Serodiagnosis of the equine infectious anaemia by the detection of the
equine infectious anaemia virus antibodies that develop 2-6 weeks post
infection.
USES
In keeping with the enclosed Directions for use.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Kit with 250 tests/bottle.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

GAMAROM IFD - PPC


KIT FOR CLASSICAL SWINE FEVER DIAGNOSIS
BY DIRECT IMMUNOFLUORESCENCE

COMPONENTS
Bottle of 1 ml of fluorescent conjugate
Two bottles of diluent
INDICATIONS
Diagnosis of the classical swine fever using sternal red marrow smears or
cryo-sections of organs from pigs or wild boars.
RECOMMENDATIONS
The conjugate working dilution indicated in the directions for use
accompanying the kit should be used. For an as good as possible
preservability, the conjugate is recommended to be fractioned into smaller
amounts (0.1-0.2 ml) as to avoid repeated freezings-thawings.
STORAGE
At -20oC.
PACKAGING
Box containing the kit components.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

HAEMAGGLUTININ PI3
PI3 (HGLT PI3) HAEMAGGLUTININ
(freeze-dried)

COMPOSITION
Parainfluenza type 3 virus grown on cell cultures.
INDICATIONS
Cattle, sheep, horses: Serodiagnosis of parainfluenza type 3 virus
infection by haemagglutination inhibition.
The working dilution (4 haemagglutinating units) is determined by
haemagglutination before each use in the haemagglutination inhibition
test.
REMARKS
In case only a part of haemagglutinin is needed, the respective amount
will be taken out under sterile conditions, the remainder being kept only
frozen until a new usage.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 2 or 5 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

HAEMOLYSIN
ANTI-SHEEP ERYTHROCYTE HAEMOLYTIC SERUM
(freeze-dried)

COMPOSITION
Blood serum of rabbits hyperimmunised with sheep red blood cells.
INDICATIONS
Preparation of the haemolytic system necessary in complement fixation.
USES
The number of the haemolysing doses used to prepare the haemolytic
system depends on the complement fixation technique used.
The product is rehydrated in 1 ml of distilled water, and then used
depending on its titre and the complement fixation technique required
number of haemolysing doses.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 1 or 2 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

HEMORAGITEST
KIT FOR RABBIT HAEMORRHAGIC DISEASE DIAGNOSIS BY HAEMAGGLUTINATION-HAEMAGGLUTINATION
INHIBITION

COMPONENTS
Antigen: Inactivated haemorrhagic disease virus
Positive serum from immunised rabbits (freeze-dried)
Negative serum from normal rabbits (freeze-dried)
INDICATIONS
Serodiagnosis of the infection with the rabbit haemorrhagic disease virus.
STORAGE
At 4o C, protected from light.
PACKAGING
Box with:
An antigen bottle
A positive serum vial
A negative serum vial
A diluent bottle

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ID - SPECITEST B
KIT FOR BOVINE SPECIES IDENTIFICATION
BY AGAR GEL IMMUNODIFFUSION

COMPONENTS
Anti-ox serum: From rabbits/goats hyperimmunised with a bovine normal
serum or a bovine globulinic concentrate; it contains antibodies that
precipitate in the presence of the specific antigen.
Ox muscle tissue extract: Proteinic suspension obtained by triturating a
fragment of bovine muscle.
INDICATIONS
Control of food as to identify the meat origin species; also, in forensic
medicine to identify blood samples.
USES
According to the Directions for use.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box with:
1 bottle of 1 or 2 ml of anti-ox serum = 100 or 200 doses
1 bottle of 2 or 4 ml of ox muscle tissue extract = 100 or 200 doses
1 bottle of 8 ml of diluent

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ID - SPECITEST C
KIT FOR CANINE SPECIES IDENTIFICATION
BY AGAR GEL IMMUNODIFFUSION

COMPONENTS
Anti-dog serum: From rabbits/goats hyperimmunised with a canine
normal serum or a canine globulinic concentrate; it contains antibodies
that precipitate in the presence of the specific antigen.
Dog muscle tissue extract: Proteinic suspension obtained by triturating a
fragment of canine muscle.
INDICATIONS
Control of food as to identify the meat origin species; also, in forensic
medicine to identify blood samples.
USES
According to the Directions for use.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box with:
1 bottle of 1 or 2 ml of anti-dog serum = 100 or 200 doses
1 bottle of 2 or 4 ml of dog muscle tissue extract = 100 or 200 doses
1 bottle of 8 ml of diluent

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ID - SPECITEST P
KIT FOR PORCINE SPECIES IDENTIFICATION
BY AGAR GEL IMMUNODIFFUSION

COMPONENTS
Anti-pig serum: From rabbits/goats hyperimmunised with a porcine
normal serum or a porcine globulinic concentrate; it contains antibodies
that precipitate in the presence of the specific antigen.
Pig muscle tissue extract: Proteinic suspension obtained by triturating a
fragment of porcine muscle.
INDICATIONS
Control of food as to identify the meat origin species; also, in forensic
medicine to identify blood samples.
USES
According to the Directions for use.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Box with:
1 bottle of 1 or 2 ml of anti-pig serum = 100 or 200 doses
1 bottle of 2 or 4 ml of pig muscle tissue extract = 100 or 200 doses
1 bottle of 8 ml of diluent

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LEPTOSER
AGGLUTINATING LEPTOSPIRA SERUM

COMPOSITION
Sera from hyperimmunised rabbits. The microagglutination titre is >
1/3200.
INDICATIONS
In microagglutination to:
Control the identity of the strains used for diagnosis and vaccines
production.
Establish the agglutinability of the Leptospira cultures used in the
microagglutination serodiagnosis.
Preliminarily identify the newly isolated Leptospira strains.
USES
In keeping with the enclosed Directions for use.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 10 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

MALLEIN
MALLEIN PPD

COMPOSITION
Protein derivative from Burkholderia mallei (Pseudomonas mallei )
cultures, solubilised in a liquid preservative.
INDICATIONS
Allergic diagnosis of glanders by the intradermopalpebral and
subcutaneous tests.
ADMINISTRATION AND DOSAGE
Intradermopalpebral test: 0.1 ml into the lower eyelid derma, a few mm
from its free edge.
Subcutaneous test: 1 ml on the neck side.
CONTRAINDICATIONS
Horses with over 38oC should not be subcutaneously inoculated. No intradermopalpebral inoculation should be applied in case of advanced
glanders, cachexia, anasarca, strangles, ocular conditions.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 5 or 10 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

MORVOSET
KIT FOR GLANDERS DIAGNOSIS BY COMPLEMENT FIXATION

COMPONENTS
Glanders antigen: Heat-inactivated and ultrasonicated Burkholderia
mallei (Pseudomonas mallei) culture.
Positive serum: From horses and/or guinea pigs experimentally
sensitised with the glanders antigen.
Negative serum: From normal Burkholderia mallei antibody free horses.
INDICATIONS
Ducks and geese glanders diagnosis by complement fixation in veterinary
laboratories.
STORAGE
At 2-8o C, protected from light.
PACKAGING
Box with:
Glanders antigen for complement fixation (liquid/freeze-dried):
Bottle of 1 ml = 250 doses
Glanders positive serum (liquid/freeze-dried):
Bottle of 1 ml = 10 doses
Glanders negative serum (liquid/freeze-dried):
Bottle of 1 ml = 10 doses

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PARAMYCOSET
KIT FOR PARATUBERCULOSIS DIAGNOSIS
BY COMPLEMENT FIXATION
A. MYCOBACTERIUM PARATUBERCULOSIS PROTOPLASMA ANTIGEN FOR COMPLEMENT
FIXATION (freeze-dried)

COMPOSITION
Ultrasonicated Mycobacterium paratuberculosis (Johnei) extract.
INDICATIONS
Diagnosis of paratuberculosis by the complement fixation test. The
antigen is reconstituted, before use, in distilled water and then inactivated
at 60oC for 30 minutes.
DOSAGE
As label stated.
PRECAUTIONS
Old, infected or haemolysed sera will not be used.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 1 ml equivalent to 66-250 doses.
B.ANTI-MYCOBACTERIUM
PARATUBERCULOSIS
SERUM
FOR
COMPLEMENT FIXATION (freeze-dried)
COMPOSITION
Serum expressed after the clotting of paratuberculosis-immunised cattle
blood.
INDICATIONS
Positive control serum in complement fixation.
DOSAGE
0.1 ml.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 1 ml equivalent to 10 doses.
C. NEGATIVE SERUM (freeze-dried)
COMPOSITION
Normal bovine serum free from Mycobacterium paratuberculosis
antibodies.
INDICATIONS
Negative control serum in complement fixation.
DOSAGE
0.1 ml.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Vial of 1 ml equivalent to 10 doses.
MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

PARATUBERCULIN
Paratuberculin PPD

COMPOSITION
Specific protein extracted from Mycobacterium paratuberculosis cultures
in a liquid preservative.
INDICATIONS
Cattle, sheep, goats: Allergic diagnosis of paratuberculosis in keeping with
the diagnosing directions for these species.
ADMINISTRATION AND REACTION INTERPRETATION
The paratuberculin dose is 0.1 ml administered intradermally.
Cattle: Strictly on the neck side previously to the avian tuberculin and on
the same line with it.
Sheep, goats: Into the thoracal wall close to the axillary area, behind the
elbow, where the skin is not woolly.
The reaction is interpreted as with tuberculination.
CONTRAINDICATIONS
It should not be used earlier than 60 days since another allergic
examination with paratuberculin or tuberculin.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 20, 50 or 100 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TUBERCULIN A
AVIAN TUBERCULIN PPD

COMPOSITION
Tuberculo-protein extracted from Mycobacterium avium.
INDICATIONS
Allergic diagnosis of avian tuberculosis by the tuberculin and comparative
tests in pigs and cattle.
ADMINISTRATION AND DOSAGE
Cattle, pigs: The reaction reading and interpretation are in keeping with
the Directions for use accompanying the product.
Poultry: The reaction is read 48 hours later.
The inoculation dose is 0.1 ml applied intradermally.
CONTRAINDICATIONS
Earlier than 60 days since the last tuberculination.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 20, 50 or 100 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

TUBERCULIN B
BOVINE TUBERCULIN PPD

COMPOSITION
Tuberculo-protein extracted from Mycobacterium bovis.
INDICATIONS
Allergic diagnosis of tuberculosis in cattle and pigs by the tuberculin and
comparative tests in agreement with the Directions for use for these
species.
ADMINISTRATION AND DOSAGE
The 0.1 ml dose is intradermally inoculated into the third middle of the
neck side (cattle) or at the ear basis (pigs).
CONTRAINDICATIONS
Earlier than 60 days post another skin test with tuberculins or
paratuberculin.
STORAGE
At 2-8oC, protected from light.
PACKAGING
Bottle of 20, 50 or 100 doses.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

E&Z FIT MUZZLE FOR DOGS & CATS

INDICATIONS
In public places where pets should not be left unsupervised, and with very
good results, in veterinary laboratories.
It is particularly resistant, as well as flexible and comfortable to use.
SIZES
It is available in a varied range of sizes, differentiated by numbers
depending on the dog/cat size and breed.
Dogs
Cats
Number
1 2 3 4 5 6
7
8
Diameter (cm)
12 16
20 22
24 26
29
14
USES
The muzzle is placed over the pets muzzle allowing it a little looseness.
The strips of the muzzle are placed behind the pets ears and the buckle is
buckled. If necessary, the strip end may be pulled as to adjust the muzzle
on the head.
PRECAUTIONS
The muzzle should not be kept on the pets head too long.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

HAPPY SBFP
ANTISEBORRHEIC, -BACTERIAL, -FUNGAL, -PARASITIC SHAMPOO

COMPOSITION
Ichthyol, iodine and permethrin in a special, soothing shampoo base.
INDICATIONS
Treatment of dry or adipose seborrhea.
Antibacterial and -fungal treatment of the derm.
It destroys lice and mites.
USES
The animals fur is thoroughly wetted with warm water, and then applied
with a shampoo amount enough to foam.
The fur is gently massaged, protecting the animals eyes, ears and
genitalia. For higher therapeutic effects, the foam is allowed to be in
contact with the fur for 10-20 minutes.
The fur is thoroughly rinsed with water, and then dried against a towel or
in warm air.
The treatment is applied whenever necessary or as directed by the
veterinarian.
PRECAUTIONS
It is toxic if swallowed.
It will not be used on the damaged or acutely inflamed skin. Should
irritations occur, the usage will be discontinued and veterinary advice
sought.
The direct contact with the eyes should be avoided.
It should not be used on cats.
Once emptied, the bottle will be disposed of!
STORAGE
At 15-25oC.
PACKAGING
Bottle of 200 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

HAPPY SG
HYPOALLERGENIC SHAMPOO

COMPOSITION
Pantothenyl alcohol in a special, soothing shampoo base.
INDICATIONS
It is a shampoo for routine washing that cleanses efficiently and restores
the natural lustre of the dog and cats fur.
It does not influence the animalss natural smell if used appropriately.
USES
The animals fur is thoroughly wetted with warm water, and then applied
with a shampoo amount enough to foam.
The fur is gently massaged, protecting the animals eyes, ears and
genitalia.
The fur is thoroughly rinsed with water, and then dried against a towel or
in warm air.
The treatment is as directed by the veterinarian.
PRECAUTIONS
The direct contact with the eyes, ears and reproductive organs should be
avoided.
STORAGE
At 15-25oC.
PACKAGING
Bottle of 200 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

HAPPY SP
ANTIPARASITIC SHAMPOO

COMPOSITION
Permethrin in a special, soothing shampoo base.
INDICATIONS
Destruction of lice and mites. It has a deodorising effect, and restores the
natural lustre of the dog and cats fur.
USES
The animals fur is thoroughly wetted with warm water, and then applied
with a shampoo amount enough to foam.
The fur is gently massaged, protecting the animals eyes, ears and
genitalia. For higher therapeutic effects, the foam is allowed to be in
contact with the fur for 10-20 minutes.
The fur is thoroughly rinsed with water, and then dried against a towel or
in warm air.
The treatment is weekly or as directed by the veterinarian.
PRECAUTIONS
The eye contact should be avoided. In case of ocular contact, the washing
with water should be immediate. Should the irritation persist, veterinary
advice will be sought.
Once emptied, the bottle will be disposed of!
STORAGE
At 15-25oC.
PACKAGING
Bottle of 200 ml.

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

LEASHES - COLLARS
.

PRESENTATION
The leashes and collars are of parachute cord.
They are recommended to be used in public places where pets should not
be left unsupervised.
They are particularly resistant, flexible and comfortable to use.
Their advantage is that they may be hygienised through washing with
water and detergents.
They come in a great variety of dimensions and colours for the full content
of pet owners.
Width
10 mm

15 mm
Collars

25 mm

Width

Length
20 cm
25 cm
30 cm
35 cm
30 cm
35 cm
40 cm
45 cm
50 cm
45 cm
50 cm
55 cm
60 cm
65 cm
70 cm

Royal blue
Light blue
Yellow-green
Brown
Black
Red
Pink

Simple

Simple
Double

Simple
Double

Length

Colour

Depth

120 cm

Royal-blue
Light blue
Yellow-green
Brown
Black
Red
Pink

180 cm
120 cm
15 mm
180 cm

25 mm

Depth

Royal blue
Brown
Black
Red

10 mm
Leashes

Colour

60 cm
120 cm
180 cm
60 cm
120 cm

Royal-blue
Brown
Black
Red

Simple
Simple
Double

Simple
Double

MANUFACTURER: PASTEUR INSTITUTE, BUCHAREST, ROMANIA

ALPHABETIC PRODUCTS INDEX


ACETOSTOP
AD3E
AGAVAC
ALEXIN
AMINOPHENAZONE
AMINOVIT
AMOXAN 40
AMPICILLIN 100
AMPICILLIN 250
ANATET
ANEMIN P
ANTIMYCOTIC OINTMENT
ANTRAVAC
ASCOMICIN
AUVAC
AVISAR
AVOMEC
BIAVAC
BIPAST B
BIVIRAL B
BRONHOSTIM
BRONVAC
BROVSET
BRUCEFIX
BRUCELINA B
BRUCELINA P
BRUCEROBEN
BRUCEROCAN
BRUCETIL
BVD - MD - VAC
CAFFEINE - SODIUM BENZOATE 25%
CALCIUM - MAGNESIUM
CALCIUM BOROGLUCONATE
CANIDER U
CHLAMYDIOFIX
CLORODIN U
CLOROSTATIC
COCCISTOP S
COLISER B
COLISER P
COLIVAC P
COLUMBO - DIV
COLUMBOVAC
DEO - VET
DERMOSEPT
DEXOGEN
DI - COL
DI - GAL
DIAZINOL
DIGESTIM
DISER
DIZENTER
E&Z FIT MUZZLE FOR DOGS & CATS
ECTOCANIGAL

ECVIPARVAC
ECVIPAST
ECVIPAST N
EFFERVESCENT AND FOAMING
PESSARIES WITH NEOMYCIN AND
OXYTETRACYCLINE
ELIBRUCELLA
ELITRICH
EMFIVAC
ENERGOSOL
ENROBACT
ENROFLOXACIN 10%
ENROFLOXACIN 10%
ENROFLOXACIN 2.5%
ENROFLOXACIN 25
ENROFLOXACIN 5
ENROFLOXACIN 5%
ENROFLOXACIN 50
ENZOOTIC BOVINE LEUCOSIS KIT
EQUINE INFECTIOUS ANAEMIA KIT
EQVAMEC P
ERINVAC
EVOMEC
FENAZON
FTALIPEPS 250 mg
FTALIPEPS 50 mg
GAMAROM IFD - PPC
GENTAMYCIN 10%
GENTAMYCIN 10%
GENTAMYCIN 5%
GENTOCIN DOSER
GENTOCIN OPHTHALMIC
GENTOCIN OTIC
GERMOSTOP ANTIMASTITIS
GERMOSTOP BUCCAL
GERMOSTOP DERMATOLOGICAL
GERMOSTOP FOR MEDICAL
INSTRUMENTS
GERMOSTOP FOR THE UDDER
GERMOSTOP HEXASOL SCRUB
GERMOSTOP HEXASOL SURGICAL
GERMOSTOP L
GERMOSTOP P
GERMOSTOP SHAMPOO
GLUCOSE 10%
GLUCOSE 33%
GUMBOINVAC
HAEMAGGLUTININ PI3
HAEMOLYSIN
HAPPY SBFP
HAPPY SG
HAPPY SP
HELMIX
HELMIZOL A 10

HELMIZOL A 2.5
HEMORAGITEST
HEMORAGIVAC
IBR - IPV VAC
ID - SPECITEST B
ID - SPECITEST C
ID - SPECITEST P
INDOMETHACIN
IOD - POVIDONA 10%
IODINE TINCTURE
IODOFORMED ETHER 5 %
IVER - MITE OTIC
IVER - MIX
LARINGOVAC
LEASHES - COLLARS
LEPTOCANIVAC
LEPTOSER
LEPTOVAC
LIN - SPE - MIX 22
LINCOMYCIN - SPECTINOMYCIN 2.2%
LINCOMYCIN - SPECTINOMYCIN 4.4%
LINCOMYCIN 100
LINCOMYCIN 11%
LINCOMYCIN 200
LINCOMYCIN 4.4%
LINCOVET 10
MAGNESIUM SULPHATE
MALLEIN
MAMIVAC
MASTIKER E
MEDIODINE SCRUB
MEDIODINE SOLUTION
METHIONINE
METHYLENE BLUE 1%
MICOCID
MICODERMIN
MICOVIT
MITE EMULSION
MORVOSET
MYCOVAC
ND - GUMBOINVAC
ND - SINCO - GUMBOINVAC
ND - SINCOVAC
NEDEVAC
NEO - MINE - VIT P
NEOBACITRACIN
NEOHEXIDIN
NEOMYCIN SULPHATE 10 %
NEOTYL
NEWVAC LA SOTA
NEWVAC LS79
OCULIN N
OPTI - CLOR
OTOSTATIC
OTOSTOP N
OTTO - CLEANS
OVIPARVAC
OVIZOL 300

OXICOR 5%
OXIPAN
OXIRET 20%
OXYTETRACYCLINE
OXYTETRACYCLINE 10%
OXYTETRACYCLINE 20%
OXYTETRACYCLINE 20%
OXYTETRACYCLINE HYDROCHLORIDE
PARAMYCOSET
PARAMYCOVAC
PARATUBERCULIN
PARVOCAN
PASTAZOL 100 mg
PASTAZOL 25 mg
PASTIGAL T
PEN STREP
PENTACAN
PESTIVAC
PESTRUVAC
PET - SPRAY
PHYSIOLOGIC SALINE
PILOCARPINE
PNEUMOSUIVAC
POLIMASTIVAC
PRAZYTEL
PREMIX E-150
PRO - CAL
PRO - VITE
PROLIZ
PRURITAK
PYRATEL CD
PYRATEL EQ
PYRATEL PREMIX
RABIVAC E
RABIVAC E CATS AND DOGS
REHIDRASOL
REHIDRAVIT
RINOVAC B
ROMPERVAC ABCD
ROMPERVAC AC
ROSTODERM
RUVAC
SALMOVAC Sm 237
SALMOVIN
SCABATOX
SEPTIVAC
SEROGAN
SEROGAN AC
SERVIPAST
SINCOVAC
SINGAL 5 mg
SODIUM IODIDE
STRESSIN
SUIGET
SUIGET MODIFIED LIFE
SUIPASTVAC
SULFASEPT
SULFATYL 100

SUPER KILLER 25 EC
TESER
TETRACYCLINE 100
TETRACYCLINE 250
TETRAINVAC
TETRAVAC B
TILOMETRIN
TRICHINOSTOP
TRICOVAC
TRIVIRAL B
TRIVIROCAN
TUBERCULIN A
TUBERCULIN B
TYLAROM 200
TYLAROM 50
VAGINAL OXYTETRACYCLINE AND
NEOMYCINE SUPPOSITORIES
VAGINAL OXYTETRACYCLINE
SUPPOSITORIES
VALBAZEN 10%
VALBAZEN 2.5%
VAMEX
VERMIZOL A 10
VERMIZOL A 100
VERMIZOL A 50
VETASED
VITAMIN AD3E
VITAMIN B1 5 %
VITAMIN B1 + B6
VITAMIN B6 5 %
VITAMIN C 10%
VITAMIN K3

PHARMACEUTICAL PRODUCTS INDEX


ACCESSORIES
E&Z FIT MUZZLE FOR DOGS & CATS
LEASHES - COLLARS

ANAESTHETICS, TRANQUILLISERS
VETASED

ANTIBIOTICS

AMOXAN 40
AMPICILLIN 100
AMPICILLIN 250
DIZENTER
EFFERVESCENT AND FOAMING
PESSARIES WITH NEOMYCIN AND
OXYTETRACYCLINE
ENROBACT
ENROFLOXACIN 2.5%
ENROFLOXACIN 5%
ENROFLOXACIN 5
ENROFLOXACIN 10%
ENROFLOXACIN 10%
ENROFLOXACIN 25
ENROFLOXACIN 50
GENTAMYCIN 5%
GENTAMYCIN 10%
GENTAMYCIN 10%
LINCOMYCIN 4.4%
LINCOMYCIN 11%
LINCOMYCIN 100
LINCOMYCIN 200
LINCOMYCIN - SPECTINOMYCIN 2.2%
LINCOMYCIN - SPECTINOMYCIN 4.4%
LINCOVET 10
LIN - SPE - MIX 22
MASTIKER E
MICOVIT
NEOBACITRACIN
NEOHEXIDIN
NEO - MINE - VIT P
NEOMYCIN SULPHATE 10 %
OTOSTOP N
OXICOR 5%
OXIPAN
OXIRET 20%
OXYTETRACYCLINE
OXYTETRACYCLINE 10%
OXYTETRACYCLINE 20%
OXYTETRACYCLINE 20%
OXYTETRACYCLINE HYDROCHLORIDE
PASTIGAL T
PEN STREP
PRURITAK
SULFATYL 100

TETRACYCLINE 100
TETRACYCLINE 250
TILOMETRIN
TYLAROM 50
TYLAROM 200
VAGINAL OXYTETRACYCLINE AND
NEOMYCINE SUPPOSITORIES
VAGINAL OXYTETRACYCLINE
SUPPOSITORIES

ANTIDIARRHOEICS
GENTOCIN DOSER

ANTIINFLAMMATORIES
AMINOPHENAZONE
FENAZON
INDOMETHACIN
IODOFORMED ETHER 5 %

ANTIPARASITICS
AVOMEC
CANIDER U
COCCISTOP S
DIAZINOL
ECTOCANIGAL
ECVIPAST
ECVIPAST N
EQVAMEC P
EVOMEC
HELMIZOL A 2.5
HELMIZOL A 10
HELMIX
IVER - MIX
MICOCID
OVIZOL 300
PASTAZOL 25 mg
PASTAZOL 100 mg
PET - SPRAY
PRAZYTEL
PYRATEL CD
PYRATEL EQ
PYRATEL PREMIX
SCABATOX
SINGAL
TRICHINOSTOP
VALBAZEN 2.5 %
VALBAZEN 10 %
VERMIZOL A 10
VERMIZOL A 50
VERMIZOL A 100

CHEMOTHERAPEUTICS
FTALIPEPS 50 mg

FTALIPEPS 250 mg

OTOSTATIC
OTTO - CLEANS

DISINFECTANTS/
ANTIMICROBIALS

SHAMPOOS

DEO - VET
GERMOSTOP ANTIMASTITIS
GERMOSTOP BUCCAL
GERMOSTOP DERMATOLOGICAL
GERMOSTOP FOR MEDICAL
INSTRUMENTS
GERMOSTOP FOR THE UDDER
GERMOSTOP HEXASOL SCRUB
GERMOSTOP HEXASOL SURGICAL
GERMOSTOP L
IOD - POVIDONA 10%
IODINE TINCTURE
MEDIODINE SCRUB
MEDIODINE SOLUTION

FEED ADDITIVES
ANEMIN P
GERMOSTOP P
PREMIX E-150
STRESSIN

HORMONAL PRODUCTS
PROLIZ

INSECTICIDES

SUPER KILLER 25 EC

REHYDRATION PRODUCTS
ENERGOSOL
REHIDRASOL
REHIDRAVIT

OINTMENTS/COLLYRIA
ANTIMYCOTIC OINTMENT
ASCOMICIN
CLORODIN U
DERMOSEPT
GENTOCIN OPHTHALMIC
MICODERMIN
NEOTYL
OCULIN N
OPTI - CLOR
SULFASEPT

OTIC SOLUTIONS
CLOROSTATIC
DEXOGEN
GENTOCIN OTIC
IVER - MITE OTIC
MITE EMULSION

GERMOSTOP SHAMPOO
HAPPY SBFP
HAPPY SG
HAPPY SP

VACCINES/SERA/REAGENTS

AGAVAC
ALEXIN
ANATET
ANTRAVAC
AUVAC
AVISAR
BIAVAC
BIPAST B
BIVIRAL B
BRONVAC
BROVSET
BRUCEFIX
BRUCELINA B
BRUCELINA P
BRUCEROBEN
BRUCEROCAN
BRUCETIL
BVD - MD - VAC
CHLAMYDIOFIX
COLISER B
COLISER P
COLIVAC P
COLUMBO - DIV
COLUMBOVAC
DI - COL
DI - GAL
DISER
ECVIPARVAC
ELIBRUCELLA
ELITRICH
EMFIVAC
ENZOOTIC BOVINE LEUCOSIS KIT
EQUINE INFECTIOUS ANAEMIA KIT
ERINVAC
GAMAROM IFD - PPC
GUMBOINVAC
HAEMAGGLUTININ PI3
HAEMOLYSIN
HEMORAGITEST
HEMORAGIVAC
IBR - IPV VAC
ID - SPECITEST B
ID - SPECITEST C
ID - SPECITEST P
LARINGOVAC
LEPTOCANIVAC
LEPTOSER

LEPTOVAC
MALLEIN
MAMIVAC
MORVOSET
MYCOVAC
ND - GUMBOINVAC
ND - SINCO - GUMBOINVAC
ND - SINCOVAC
NEDEVAC
NEWVAC LA SOTA
NEWVAC LS79
OVIPARVAC
PARAMYCOSET
PARAMYCOVAC
PARATUBERCULIN
PARVOCAN
PENTACAN
PESTIVAC
PESTRUVAC
PNEUMOSUIVAC
POLIMASTIVAC
RABIVAC E
RABIVAC E CATS AND DOGS
RINOVAC B
ROMPERVAC ABCD
ROMPERVAC AC
RUVAC
SALMOVAC Sm 237
SALMOVIN
SEPTIVAC
SEROGAN
SEROGAN AC
SERVIPAST
SINCOVAC
SUIGET
SUIGET MODIFIED LIFE
SUIPASTVAC
TESER
TETRAINVAC

TETRAVAC B
TRICOVAC
TRIVIRAL B
TRIVIROCAN
TUBERCULIN A
TUBERCULIN B

VITAMINS/AMINO ACIDS/
ANABOLIC PRODUCTS

ACETOSTOP
AD3E
AMINOVIT
DIGESTIM
GLUCOSE 10%
GLUCOSE 33%
METHIONINE
PRO - CAL
PRO - VITE
VAMEX
VITAMIN AD3E
VITAMIN B1 5 %
VITAMIN B1 + B6
VITAMIN B6 5 %
VITAMIN C 10%
VITAMIN K3

VARIA

BRONHOSTIM
CAFFEINE - SODIUM BENZOATE 25%
CALCIUM BOROGLUCONATE
CALCIUM - MAGNESIUM
MAGNESIUM SULPHATE
METHYLENE BLUE 1%
PHYSIOLOGIC SALINE
PILOCARPINE
ROSTODERM
SODIUM IODIDE

PRODUCTS INDEX - ACTIVE INGREDIENTS


ALBENDAZOLE

ECVIPAST
ECVIPAST N
HELMIZOL A 2.5
HELMIZOL A 10
HELMIX
OVIZOL 300
PASTAZOL 25 mg
PASTAZOL 100 mg
SINGAL
TRICHINOSTOP
VALBAZEN 2.5 %
VALBAZEN 10 %
VERMIZOL A 10
VERMIZOL A 50
VERMIZOL A 100

AMPICILLIN

AMPICILLIN 100
AMPICILLIN 250

AMINOPHENZONE
AMINOPHENZONE

AMITRAZ
CANIDER U
SCABATOX

AMOXICILLIN
AMOXAN 40

AZAMETHIPHOS
ECTOCANIGAL

BACITRACIN

NEOBACITRACIN
OTOSTATIC

BACTERIAL ANTIGENS
AGAVAC
ANATET
ANTRAVAC
AVISAR
BIPAST B
BROVSET
BRUCEFIX
BRUCELINA B
BRUCELINA P
BRUCEROBEN
BRUCEROCAN
BRUCETIL
COLIVAC P
ELIBRUCELLA
EMFIVAC

LEPTOCANIVAC
LEPTOVAC
MALLEIN
MAMIVAC
MORVOSET
MYCOVAC
NEWVAC LA SOTA
NEWVAC LS79
OVIPARVAC
PARAMYCOSET
PARAMYCOVAC
PARATUBERCULIN
PNEUMOSUIVAC
POLIMASTIVAC
ROMPERVAC ABCD
ROMPERVAC AC
RUVAC
SALMOVAC Sm 237
SALMOVIN
SEPTIVAC
SUIGET
SUIGET MODIFIED LIFE
TRICOVAC
TUBERCULIN A
TUBERCULIN B

CAFFEINE

CAFFEINE - SODIUM BENZOATE 25%

CALCIUM - MAGNESIUM
CALCIUM
PRO - CAL

CHLORHEXIDINE

CLORODIN U
GERMOSTOP ANTIMASTITIS
GERMOSTOP BUCCAL
GERMOSTOP DERMATOLOGICAL
GERMOSTOP FOR MEDICAL
INSTRUMENTS
GERMOSTOP FOR THE UDDER
GERMOSTOP HEXASOL SCRUB
GERMOSTOP HEXASOL SURGICAL
GERMOSTOP L
GERMOSTOP P
GERMOSTOP SHAMPOO
NEOHEXIDIN

CHLORAMPHENICOL
CLOROSTATIC
OPTI - CLOR

CYPERMETHRIN

SUPER KILLER 25 EC

DETERGENT
DEO VET
HAPPY SG

DEXAMETHASONE
DEXOGEN
FENAZON
GENTOCIN OTIC

DIAGNOSTIC REAGENTS / SERA


ALEXIN
GAMAROM IFD - PPC
HAEMOLYSIN
ID - SPECITEST B
ID - SPECITEST C
ID - SPECITEST P
LEPTOSER

DIAZINONE
DIAZINOL

ENROFLOXACIN

ENROBACT
ENROFLOXACIN 2.5%
ENROFLOXACIN 5%
ENROFLOXACIN 5
ENROFLOXACIN 10%
ENROFLOXACIN 10%
ENROFLOXACIN 25
ENROFLOXACIN 50

222

INDOMETHACIN

103

285
105
126

134
251
265
267
269
270
271
272

FLUOCINOLONE
CLOROSTATIC

GENTAMYCIN

DEXOGEN
GENTAMYCIN 5 %
GENTAMYCIN 10 %
GENTAMYCIN 10 %
GENTOCIN DOSER
GENTOCIN OPHTHALMIC
GENTOCIN OTIC

GLUCOSE

GLUCOSE 10%
GLUCOSE 33%

ICHTYOL

DERMOSEPT
HAPPY SBFP

IODINE

IODINE TINCTURE
IODOFORMED ETHER 5%
IOD POVIDONA
MEDIODINE SCRUB
MEDIODINE SOLUTION
SODIUM IODIDE

IVERMECTIN

AVOMEC
EQVAMEC P
EVOMEC
IVER - MITE OTIC
IVER - MIX

KETAMINE
VETASED

106
115
117
118
119
120
121
122

123
167

LINCOMYCIN

DIZENTER
LINCOMYCIN 4.4%
LINCOMYCIN 11%
LINCOMYCIN 100
LINCOMYCIN 200
LINCOMYCIN - SPECTINOMYCIN 2.2%
LINCOMYCIN - SPECTINOMYCIN 4.4%
LINCOVET 10
LIN - SPE - MIX 22

MINERALS
101

ACETOSTOP

METHIONINE
105
129
130
131
132
133
134
145

146
104

284

150
151
152
153
168
169
218
93
124
125
154
155
237

KANAMYCIN
PRURITAK

ERYTHROMYCIN
MASTIKER E

INDOMETHACIN

AMINOVIT
METHIONINE
PREMIX E-150

METHYLENE BLUE

209
109
156
158
160
161
162
163
164

165
83
86
170

204

METHYLENE BLUE 1%

171

ECVIPAST N

112

NEGUVON

NEOMYCIN

EFFERVESCENT AND FOAMING


PESSARIES WITH NEOMYCIN AND
OXYTETRACYCLINE
MICODERMIN
NEOBACITRACIN

NEOHEXIDIN
NEO - MINE - VIT P
NEOMYCIN SULPHATE 10%
NEOTYL
OCULIN N
OTOSTATIC
OTOSTOP N
VAGINAL OXYTETRACYCLINE AND
NEOMYCINE SUPPOSITORIES

NYSTATIN
MICODERMIN
MICOVIT
OTOSTATIC
OTOSTOP N
TILOMETRIN

OXYTETRACYCLINE

DIZENTER
NEO - MINE - VIT P
OXICOR 5%
OXIPAN
OXIRET 20%
OXYTETRACYCLINE
OXYTETRACYCLINE 10%
OXYTETRACYCLINE 20%
OXYTETRACYCLINE 20%
OXYTETRACYCLINE HYDROCHLORIDE
VAGINAL OXYTETRACYCLINE
SUPPOSITORIES

ORGANIC PHOSPHATES
SUPER KILLER 25 EC

PARASITIC ANTIGENS
ELITRICH

PENICILLIN POTASSIUM
PASTIGAL T

PERMETHRIN

DIGESTIM
ROSTODERM

PROCAIN-BENZYL
PENICILLIN G
ASCOMICIN
PEN STREP

PRAZIQUANTEL
PRAZYTEL

PROGESTERON
PROLIZ

PYRANTEL

PRAZYTEL
PYRATEL CD
PYRATEL EQ
PYRATEL PREMIX

PYRETHRIN
PET - SPRAY

SALICYLIC ACID
OTTO - CLEANS

SODIUM

SODIUM IODIDE

SODIUM CHLORIDE
PHYSIOLOGIC SALINE

SPECTINOMYCIN

LINCOMYCIN - SPECTINOMYCIN 2.2%


LINCOMYCIN - SPECTINOMYCIN 4.4%
LIN - SPE - MIX 22

STREPTOMYCIN
ASCOMICIN
PEN - STREP

SULFAQUINOXALINE

HAPPY SBFP
HAPPY SP
MITE EMULSION

COCCISTOP S

PHENOL

SULPHATHIAZOLE

MICOCID

PHTHALYLSULFATHIAZOLE
FTALIPEPS 50 mg
FTALIPEPS 250 mg

PILOCARPINE
PILOCARPINE

PLANT EXTRACTS
BRONHOSTIM

SULFATYL 100

SULPHANILAMIDE
SULFASEPT

TETRACYCLINE

TETRACYCLINE 250

THERAPEUTIC IMMUNE SERA


COLISER B
COLISER P

ANTIMYCOTIC OINTMENT

ND - SINCOVAC
NEDEVAC
PARVOCAN
PENTACAN
PESTIVAC
PESTRUVAC
RABIVAC E
RABIVAC E CATS AND DOGS
RINOVAC B
SINCOVAC
SUIPASTVAC
TETRAINVAC
TETRAVAC B
TRIVIRAL B
TRIVIROCAN

VIRAL ANTIGENS

VITAMINS / MINERALS

SEROGAN
SEROGAN AC
SERVIPAST
TESER

TYLOSIN

NEOTYL
PASTIGAL T
SULFATYL 100
TILOMETRIN
TYLAROM 50
TYLAROM 200

THIURAM

AUVAC
BIAVAC
BIVIRAL B
BRONVAC
BVD - MD - VAC
COLUMBO - DIV
COLUMBOVAC
DI - COL
DI - GAL
ECVIPARVAC
ENZOOTIC BOVINE LEUCOSIS KIT
EQUINE INFECTIOUS ANAEMIA KIT
ERINVAC
GUMBOINVAC
HAEMAGGLUTININ PI3
HEMORAGITEST
HEMORAGIVAC
IBR - IPV VAC
LARINGOVAC
ND - GUMBOINVAC
ND - SINCO - GUMBOINVAC

AD3E
AMINOVIT
ANEMIN P
CALCIUM BOROGLUCONATE
ENERGOSOL
MAGNESIUM SULPHATE
MICOVIT
NEO - MINE - VIT P
PREMIX E-150
PRO - VITE
REHIDRASOL
REHIDRAVIT
STRESSIN
VAMEX
VITAMIN AD3E
VITAMIN B1 5%
VITAMIN B1 + B6
VITAMIN B6 5%
VITAMIN C 10%
VITAMIN K3

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