DRUG STUDY

Generic
Name
Brand
Name
Classificati
ons

Prescribed
and
Recommen
ded
Dosage,
Frequency,
and Route
of
Administra
tion

Generic
Name:
Essentiale
Forte

1 cap PO
TID

Brand Name:
Essentiale
Forte N
Classification
s:
Cholagogues
,
Cholelitholyti
cs, and
hepatic
Protector

Mechanism of
action

Indication

Contraindicati
on

Adverse
reaction

It was seen to
inhibit steatosis
and fibrosis in
chronic liver
damage models.
Inhibits lipid
peroxidation and
inhibit collagen
synthesis.
Principal actions
have been
through
accelerated
membrane
regeneration and
stabilization.

Nutritional
support in the
management
of damaged
liver ( due to
chronic liver
dse, liver
cirrhosis,
fatty liver,
and
intoxication
by
hepatotoxic
substance).

Known
hypersensitivity
to soya-bean
preparation/ to
any of the
excipients of
essential forte p.
due to the
content in soyabean oil,
essential forte P
may provoke
severe allergic
reactions.

Administration
of essentiale
Forte may
provoke
gastrointestinal
disorder eg,
stomach
complaints, soft
stool and
diarrhea. On
very rare
occasions,
allergic
reactions may
occur eg,
exanthema and
urticarial.

Nursing
Responsibility

1. Assess pts
hx of the
interaction
with the
drug to
avoid
allergies
reactions
2. Check NPO
of pt
his/her gag
and
swallow
reflex
3. Position pt
properly
4. Explain to
client

about the
procedure
5. Monitor
and
evaluate
client
response.

Generic
Name
Brand
Name
Classificati
ons

Prescribed
and
Recommen
ded
Dosage,
Frequency,
and Route
of
Administra
tion

Generic
Name:
Tramadol

50 mg IVTT
q 8h PRN
pain

Brand Name:
Tramadol
Classification
:

Mechanism of
action

Indication

Contraindicati
on

Adverse
reaction

Binds to
receptors in the
brain ( opiod/
narcotic
receptor) that
are important for
transmitting the
sensation of pain
from throughout

Relief of
moderate to
moderately
severe pain

Contraindicated
with allergy to
tramadol or
opiods or acute
intoxication with
alcohol or
psychotic drugs.

CNS: sedation,
dizziness,
vertigo,
headache,
confusion,
dreaming,
sweating
anxiety,
seizures

Use cautiously

Nursing
Responsibility

1. Assess pts
hx of the
interaction
with the
drug to
avoid
allergies
reactions
2. Check NPO

Analgesic
( centrally
acting)

the body to the

brain

with pregnancy,
lactation,
seizures
concomitant use
of CNS
depressants or
MAOIs renal/
hepatic
impairment

CVs:
hypotension,
tachycardia,
bradycardia
Dermatologic:
sweating,
pruritus, rash,
pallor, urticarial
GI: NV, dry
mouth,
constipation
and flatulence

of pt
his/her gag
and
swallow
reflex
3. Position pt
properly
4. Explain to
client
about the
procedure
5. Monitor
and
evaluate
client
response.

Other: potential
for abuse,
anaphylactoid
reaction

Generic
Name
Brand
Name
Classificati
ons

Prescribed
and
Recommen
ded
Dosage,
Frequency,
and Route
of

Mechanism of
action

Indication

Contraindicati
on

Adverse
reaction

Nursing
Responsibility

Administra
tion
Generic
Name:
Cefuroxime
Brand Name:
2 Gen
Classification
:
Antibiotic

750mg q8h
IVTT (-)
ANST

Second
generation
cephalosporin
that inhibit cell
wall synthesis,
promoting
osmotic
instability,
usually
bactericidal

Pharyngitis,
tonsillitis,
infection of
the urinary
and lower
respiratory
tracts and
skin structure
infections
caused by
streptococcus
pneumonae
and s.
pyogene
Haemophillus
influence
staphylococc
us aureus, e.
coli

Contraindicated
to patient
hypersensitive
to drug
Use cautiously to
patient
hypersensitive
to penicillin
because of
possibility of
cross sensitivity
with beta lactam
antibodies
Use with caution
in breastfeeding
women

Body as a
whole:
Thrombophlebiti
s IV site pain,
burning
cellulitis
Iv site: super
infections,
positive coombs
test
GI:
Diarrhea,
nausea and
vomiting,
antibiotic
associated
colitis
SKIN:
Rash, pruritus,
urticarial
Urogenital:
Increased
serum
creatinine and
Bun to

1. Assess pts
hx of the
interaction
with the
drug to
avoid
allergies
reactions
2. Check NPO
of pt
his/her gag
and
swallow
reflex
3. Position pt
properly
4. Explain to
client
about the
procedure
5. Monitor
and
evaluate
client
response.

creatinine
clearance
Generic
Name
Brand
Name
Classificati
ons

Prescribed
and
Recommen
ded
Dosage,
Frequency,
and Route
of
Administra
tion

Generic
Name:
Ursodeoxych
olic acid

500 mg 1
tab OD

Brand name:
Ursofolic
Classification
s:
Anticholelithi
c

Mechanism of
action

Indication

Contraindicati
on

Adverse
reaction

Decreased
biliary
cholesterol
saturation by
suppressing
hepatic
synthesis and
secretion of
cholesterol and
by inhibiting its
intestinal
absorption. The
reduced
cholesterol
saturation
permits the
gradual
solubilization of

Indicated for
dissolution of
cholesterol
gallstones in
selected pts
with
uncomplicate
d radiolucent
gallstones

Contraindicated
to pts who are
sensitive to
other bile acid
products may be
sensitive to
ursodiol,
lactating
patients and
pregnant women
patients who
have hepatic
function
impairment

Back pain,
diarrhea, are
the most
frequent
adverse effect
of the drug.
Incidence less
frequent or
rare:
Alopecia,
constipation,
dizziness,
dyspepsia,
nausea,
psoriasis,
exarbation or
preexisting,

Nursing
Responsibility

1. Assess pts
hx of the
interaction
with the
drug to
avoid
allergies
reactions
2. Check NPO
of pt
his/her gag
and
swallow
reflex
3. Position pt
properly
4. Explain to
client

cholesterol from
gallstones

Generic
Name
Brand
Name
Classificati
ons

Generic
Name:
Paracetamol
Brand Name:
Biogesic
Classification
:

Prescribed
and
Recommen
ded
Dosage,
Frequency,
and Route
of
Administra
tion
500g1 tab q
4h PRN
fever

vomiting.

Indication

Contraindicati
on

Adverse
reaction

Temporary
relief of pain
and
discomfort
from
headache,
fever, cold,
flu, minor
muscular

None (except
hypersensitivity
to drug)

Hematologic:
hemolytic
anemia,
leukopenia,
neutropenia,
pancytopenia,
thrombocytope
nia

Mechanism of
action

Paracetamol
may cause
analgesia by
inhibiting CNS
prostaglandin
synthesis. The
mechanism of
morphine is
believed to

about the
procedure
5. Monitor
and
evaluate
client
response.

Nursing
Responsibility

1. Assess pts
hx of the
interaction
with the
drug to
avoid
allergies
reactions
2. Check NPO

Analgesia
(non-opiod),
antipyretics

involve
decreased
permeability of
the cell
membrane to
sodium which
results in
diminished
transmission of
pain impulses
therefore
analgesia

ache,
overexertion,
menstrual
cramps,
toothache,
minor
arthritic pain

Hepatic: liver
damage,
jaundice
Metabolic:
hypoglycemia
Skin: rash,
urticaria

of pt
his/her gag
and
swallow
reflex
3. Position pt
properly
4. Explain to
client
about the
procedure
5. Monitor
and
evaluate
client
response.