Member of Croda International Plc

Development formulation
(*)

Cream Perfect Youth

with MEDIATONE & DERMAXYL(*) & IDEALIFT(*) & MATRIXYL 3000 (*)
SED1407155 A
(*) Mediatone: Patent pending / Dermaxyl: Patent WO 2004/101609 / Idealift PH: Patent WO 2010/136965 /
Matrixyl 3000: Patent WO 2005/048968
% by wt
Part A
Water deionised
Qsp 100
Potassium Sorbate
qs
Part B
Glycerin
Xanthan Gum
Hydroxyethyl Cellulose
Phenoxethanol
Part C
Crodafos CES-PA-(RB) [Cetearyl Alcohol & Dicetyl
Phosphate & Ceteth-10 Phosphate]
Crodamol GTCC-LQ-(MV) [Caprylic/Capric Triglyceride]
Pripure 3759-LQ-(GB) [Squalane]
Crodamol GTEH-LQ-(MV) [Triethylhexanoin]
Mediatone [Octadecenedioic Acid]
Part D
Dermaxyl [C12-15 Alkyl Benzoate (and) Tribehenin and

5.00
0.15
0.15
qs

Croda

5.00

Croda
Croda
Croda
Sederma

4.00
5.00
4.00
1.00

Sederma

3.00

Sederma

4.00

3.00
0.30

Sederma

4.00

Expressions Parfumes

0.10

Ceramide 2 (and) PEG 10 Rapeseed Sterol (and) Palmitoyl

Hexapeptide-12]

Part E
Idealift [Butylene Glycol (and) Water (and) Sorbitan
Laurate (and) Hydroxyethylcellulose (and) Acetyl
Dipeptide-1 Cetyl Ester]
Part F
Water deionised
Sodium hydroxide 30%
Part G
Matrixyl 3000 [Glycerin (and) Water (and) Butylene
Glycol (and) Carbomer (and) Polysorbate 20 (and)
Palmitoyl Tripeptide-1 (and) Palmitoyl Tetrapeptide-7]
Part H
Fragrance (Volupt)

09/15 PCS DF 023 V1 EN

Page 2/2

Member of Croda International Plc

Development formulation
Cream with NEW DOIC(*) & DERMAXYL(*) & IDEALIFT(*) & MATRIXYL 3000 (*)
SED1407155 A
(*) Mediatone: Patent pending / Dermaxyl: Patent WO 2004/101609 / Idealift PH: Patent WO 2010/136965 /
Matrixyl 3000: Patent WO 2005/048968

Method
Weigh Part A with helix stirring (s=400 rpm).
Weigh and homogenize Part B.
Add Part B to Part A with helix stirring (s=800 rpm). Allow to swell for 30 minutes.
Heat Part A+B to 75C in bain-marie.
Weigh and heat Part C to 75C in bain-marie. Mix well.
Add Part D in Part C. Homogenize well.
Add Part E into Part A+B with rotor Stator stirring (s=1000 rpm).
Pour Part C+D into Part A+B+E with Stator stirring (s=36000 rpm). Homogenize well.
Add Part F. Homogenize well.
Add Part G at around 55C, homogenize.
Then add Part H below 35C, homogenize well.
pH : 5.80 +/-0.10

This formulation has been subject to limited stability tests and has been shown to perform well. However formulators adopting this
approach should ensure to their own satisfaction long term stability and functionality. It is good practice to conduct safety tests on all
final formulations prior to marketing. Suggested uses should not be taken as an inducement to infringe any existing patents.
Non-guarantee: The information in this publication is given in good faith by Sederma by way of general guidance and for reference
purposes only. The information should not be construed as granting a license to practice any methods or compositions of matter covered
by patents. Sederma assumes no liability in relation to the information and gives no warranty regarding the suitability of the product
and/or ingredients described for a particular use. The use made of the product and/or ingredients described by the recipient and any
claims or representations made by the recipient in respect of such product and/or ingredients are the responsibility of the recipient. The
recipient is solely responsible for ensuring that products marketed to consumers comply with all relevant laws and regulations.
Sederma SAS - 29, rue du Chemin Vert BP 33 - 78612 Le Perray-en-Yvelines Cedex - France
Tel ++33 1 34 84 10 10 Fax ++33 1 34 84 11 30

09/15 PCS DF 023 V1 EN