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Regulation of Cell Cycle Review

Terms:
1. Cell Cycle: a series of events that takes place in a cell as it grows and divides.
2. Carcinogens: a substance capable of causing cancer in living tissue.
3. Cancer: The disease caused by an uncontrolled division of abnormal cells in a
part of the body.
4. Tumor: a swelling of a part of the body, generally without inflammation, caused
by an abnormal growth of tissue, whether benign or malignant.
5. Malignant: [of a disease] very virulent or infectious.
6. Benign: (of a disease) not harmful in effect: in particular, (of a tumor) not
malignant
7. Apoptosis: the death of cells that occurs as a normal and controlled part of an
organism's growth or development

Questions:
1. What are some internal factors that regulate cell cycle? Molecules found
within the cells cytoplasm such as kinases and cyclins.
2. What are some of the external factors that regulate cell cycle? Physical
signals such as cell to cell contact. Chemical signals such as growth factors and
growth hormones.
3. What are carcinogens? A substance that produces or promotes the
development of cancer.
4. Give a list of several carcinogens. Certain organic chemicals, radiation, and
viruses
5. What are cancer cells? How are they different than regular cells? They
have a number of abnormal characteristics that prevent them from functioning in
the same manner as normal cells. They divide repeatedly and form tumors in the
place of origin and in other parts of the body.
6. What are tumors? How do they explain an issue in mitosis? A swelling of a
part of the body, generally without inflammation, caused by an abnormal growth of
tissue, whether benign or malignant. Mitosis is the process that reproduces cells,
without it cancerous cells wouldnt be able to form tumors.
7. Explain the difference between malignant and benign.

Benign: Slow growing. Well circumscribed. Non-invasive. No or few symptoms. Does


not metastasize. X-ray shows lesion confined to bone.
Malignant: Rapidly growing. Not well circumscribed. Invading. Associated with pain
and disability. Metastasize. X-ray shows ill defined borders, mattled appearance
cortex broken.
8. What is apoptosis? the death of cells that occurs as a normal and controlled
part of an organism's growth or development.
9. Identify examples of natural apoptosis in cells. Hair, gut, & skin cells
10. In your opinion, what do cancer cells teach us about mitosis? Ti du de
dngx sh b ho de, Too much of something can be a bad thing

Critical Thinking:
1. Construct a chart or an illustration that compares and contrasts regular
cell growth to that of a cell with cancer:
a. Think in terms of Mitosis and apoptosis
b. Also, make sure to look at various internal and external factors at play.
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