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Guide:
Dr.U.P.Rathnakar
MD.DIH.PGDHM
ROAD MAP
Introduction
History
Definition
Concept
Cost and outcomes
Evaluation methods
Applications
Conduct of PE evaluation
Conclusion
INTRODUCTION
HISTORY
DEFINITION
ECONOMICS:
- Is the study of how society decides what
gets produced, how and for whom.
HEALTH ECONOMICS:
Branch of economics
- Study of
- How scarce resources are allocated for
the health care
- For the maintenance and
impprovement of health among people
PHARMACOECONOMIC:
CONCEPT
Cont
Cont..
Pharmacoeconomics
Outcome
Cost
COST?
Cont
Cont
COST
Intangible
Indirect
Opportunity
DIRECT
MEDICAL:
NON MEDICAL:
INDIRECT
NON MEDICAL:
OPPORTUNITY
COSTS:
OUTCOMES
Outcomes (consequence)
Clinical
(efficacy of
treatment)
Humanistic
(QOL, patient
satisfaction)
EVALUATION METHODS
Cost--minimization Analysis
Cost
Simplest
CBA.
Expressed
CEA..
Eg:
Eg:
- 4 Statins compared Fluvastatin
Lovastatin,, Simvastatin,
Lovastatin
Simvastatin, Pravastatin
- Outcome: rate of success in achieving the LDL
goal of therapy
- Cost: drug cost, physician cost, lab cost
- Fluvastatin lowest CEA ratio for LDL reduction
of 25% or less
CEA--ACEA
CEA
1.
CEA--ICEA
CEA
2.
CUA ..
Cost:
CUA.
Example, intervention A
Allows a patient to live for 3 additional years
Than if no intervention had taken place, but
only with a quality of life weight of 0.6,
Then the intervention confers 3 * 0.6 = 1.8
QALYs to the patient [A]
If intervention B confers 2 extra years of life
at a quality of life weight of 0.75,
Then it confers an additional 1.5 QALYs to
the patient. [B]
The net benefit of intervention A over
intervention B is therefore 1.8 - 1.5 = 0.3
QALYs.
Methodology
Outcome measurement
units
CMA
CEA
CBA
CUA
Application of Pharmacoeconomics:
Pharmacoeconomics:
Use ..
6. Used to justify use of pharmacy
products and pharmaceutical care
7. Principle of Pharmacoeconomic also
influences health care decision making
and individual patient care
8. Earlier clinical decisions were solely
based on outcomes. Now cost, outcome,
humanistic outcome are also considered
Cox- II inhibitors
Cox- effective pain relief
- substantially more expensive than CoxCox-1
inhibitors
- associated with lower risk of GI side effects
CONCLUSION
REFERENCE