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PA TH OPHYSIOLOGY
IUFD, UTERINE LACERATION, GDM,
ITP, NEPHROLITHIASIS, CYSTITIS
Feta l
hyperg lycemia
Maternal
Hyp erglyce mi a
PVD, Arteriosclerosis,
CAD, CVD, MI, Stroke
intracellula r calcium
Macrosomia
Severe immediate
hypogl ycemia upon birth
Urine pH foste rs
bacterial growth
Pro ne to infection
Urinary Tract Infect ion: Cystitis
Glycosuria
Infla mmation pro cess
triggere d
(+) Bacteria on
urinaly sis
Polyuri a via
osmotic diure sis
Polydip sia
(+) Erythrocy tes
on urinaly sis
Localization of chemicals
such as prostagland ins
Polyph agia
(+) Dolor:
Dysuria, hypoga stric p ain
Hemoconcentrati on
Nephrolithias is
(Calcium oxalate stone s)
(+) Productive
cough / colds
Localization of chemicals
such as prostagland ins
(+) Dolor: sore
throat, dysphagia
Platelet count
(20 mg/dL)
Platelet count
(20 mg/dL)
Ecc hym os is
Epistaxis
Pet echiae
Eas y bruising
Hemato ma formation
IV volu me
Cullen s sign
Dec. Bloo d volu me circulating
by the placen tal barr ier
Bloo d p ressur e
Renin secretio n
Feta l h eart ra te
Conversion of
Ang iote nsinogen to
Ang iote nsin I by Renin
Conversion of An giotensin I to
Ang iote nsin II by Angiotensinconverting enzyme (ACE)
RIS K FACTORS:
- Macros om ic fetus
- Oxy toc in augme nta tion
-VBAC
- Close inte rva l between
pre gnancies (2 yrs.)
- Dysfunctio nal labor
VBA C performed
2 yrs afte r CS
Dehiscence o f
sca rred area
Ineffective contractio n o f th e
myo me triu m after de live ry
Macrosomic fe tus +
oxytocin augmen tation
Continuous bleeding
into the endometrium
Uterine la ceration