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From : http://www.medscape.com/viewarticle/760100
Lisa Nainggolan
Lisa Nainggolan is a journalist for theheart.org, part of the WebMD Professional Network. She has been with
theheart.org since 2000. Previously, she was science editor of Scrip World Pharmaceutical News, covering
news about research and development in the pharmaceutical industry, and a consultant editor of Scrip
Magazine. Graduating in physiology from Sheffield University, UK, she began her career as a poisons
information specialist at Guy's Hospital before becoming a medical journalist in 1995. She can be reached
at LNainggolan@webmd.net.
Disclosure: Lisa Nainggolan has disclosed no relevant financial relationships.
Hu says water is the best thing to drink, or coffee or tea. Fruit juice is
"not a very good alternative, because of the high amount of sugar," he
adds, although if diluted with water, "it's much better than a can of
soda," he notes.
And Hu says although the current results apply only to men, prior data
from his group in women in the Nurses' Health Study [from 2009]
were comparable, "which really boosts the credibility of the findings."
Inflammation could be a pathway for impact of soda upon CHD
risk
Hu and colleagues explain that while much research has shown a link
between the consumption of sugar-sweetened beverages and type 2
diabetes, few studies have looked at the association of these drinks
with CHD.
Hence, they analyzed the associations of cumulatively averaged sugarsweetened (eg, sodas) and artificially sweetened (eg, diet sodas)
beverage intake with incident fatal and nonfatal CHD (MI) in 42 883
men in the Health Professionals Follow-up study. Beginning in 1986 and
every two years until December 2008, participants answered
questionnaires about diet and other health habits. A blood sample was
provided midway through the study.
There were 3683 CHD cases over 22 years of follow-up. Those in the
top quartile of sugar-sweetened-beverage intake had a 20% higher
relative risk of CHD than those in the bottom quartile (RR 1.20; p for
trend < 0.001) after adjustment for age, smoking, physical activity,
alcohol, multivitamins, family history, diet quality, energy intake, bodymass index, preenrollment weight change, and dieting.
Adjustment for self-reported high cholesterol, high triglycerides, high
blood pressure, and diagnosed type 2 diabetes only slightly attenuated
these associations, which suggests that drinking soda "may impact on
CHD risk above and beyond traditional risk factors," say the
researchers.
Consumption of artificially sweetened drinks was not significantly
associated with CHD (multivariate RR 1.02; p for trend=0.28).
Intake of sugar-sweetened drinks, but not artificially sweetened ones,
was also significantly associated with increased triglycerides and
several circulating inflammatory factors including C-reactive protein,
interleukin 6 (IL-6), and tumor-necrosis-factor receptor 1 (TNFr1) as
References
1. de Koning L, Malik VS, Kellogg MD et al. Sweetened beverage
consumption, incident coronary heart disease and biomarkers of
risk in men. Circulation 2012; DOI:
10.1161/CIRCULATIONAHA.111.067017. Available at:
http://circ.ahajournals.org.