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Waking the dead: Scientists reconstruct nuclear genome of extinct human being 2/10/10 2:28 PM

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Waking the Dead: Scientists Reconstruct Nuclear Genome of Extinct Birds from Dinosaurs or Other Way Around?
Human Being
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ScienceDaily (Feb. 10, 2010) — Scientists at the
enlarge
University of Copenhagen have become the first to Doggy Genes
Molecular biologists have completely
reconstruct the nuclear genome of an extinct
sequenced the first dog genome.
human being. It is the first time an ancient genome Understanding how genetics plays a
has been reconstructed in detail. role in canine diseases could lead to
new. ... > full story
The innovative technique can be
See Also: applied to museum materials and Planetary Scientists Use Hubble to Spot
ancient remains found in nature and Oxygen-Rich Soil on Moon
Health & Medicine can help reconstructing human Physicist Calls for Airline Industry to Educate
Human Biology phenotypic traits of extinct cultures Workers about Radiation Levels
Genes from where only limited remains
Hair Loss Reconstruction of the prehistoric man Inuk. (Credit: Chemists Steal Engineering Tricks from Sponges
have been recovered. It also allows
Drawing by Nuka Godfredtsen) more science videos
Fossils & Ruins for finding those contemporary
Human Evolution populations most closely related to Ads by Google
Early Humans extinct cultures revealing ancient
Fossils human expansions and migrations.
Finally, the discovery improves our Now Gen Sequencing Summit
Reference understanding of heredity and the March 15 - 19, 2010
The Genographic disease risk passed down from our San Diego, CA
Project ancestors. www​.healthtech​.com​/xgn​/seq
Mammoth Chromosome Analysis
Multiregional The spectacular results of the
research are being published in the Whole genome & targeted analysis
hypothesis w. high resolution oligo microarray
Neandertal journal Nature.
www​.genedx​.com​/genomedx
interaction with Cro- Professor Eske Willerslev and his
Magnons PhD student Morten Rasmussen, Hair Loss
from Centre of Excellence in All Your Hair Care Needs. Find
GeoGenetics at the Natural History hair loss Here.
Museum, University of Copenhagen, Denmark, led the www​.​Hair​Loss​Defense​.com
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Professor Willerslev, 38, and his team grabbed international www​.​O​O​K​I​S​A​.com​/​Hair_​Products
attention last year when they reconstructed the complete Scientists find clue
mitochondrial genomes of a woolly mammoth and an ancient to anxiety drug
human. However, the current discovery is the first time Related Stories
addiction
scientists have been able to reconstruct the 80% of the
Giant Moa Rebuilt Using Ancient DNA Shuttle Endeavour
nuclear genome that is possible to retrieve from fossil
From Prehistoric Feathers (July 2, 2009) docks with space
remains. From the genomic sequences, the team has
— Scientists have performed the first station
managed to construct a picture of a male individual who lived
in Greenland 4,000 years ago and belonged to the first DNA-based reconstruction of the giant Researchers find
culture to settle in the New World Arctic. extinct moa bird, using prehistoric feathers sex-specific lung
recovered from caves and rock shelters in New ... cancer genes
The discovery was made by analysing a tuft of hair that > read more Study shows why it
belonged to a man from the Saqqaq culture from north-
Ancient Bison Genetic Treasure is so scary to lose
western Greenland 4,000 years ago. The scientists have
Trove For Farmers (Oct. 23, 2009) — money
named the ancient human "Inuk," which means "man" or
"human" in Greenlandic. Although Inuk is more closely related Genetic information from an extinct Scientists find gene
to contemporary north-eastern Siberian tribes than to modern species of bison preserved in variant link to aging
Inuits of the present day New World Arctic, the scientists permafrost for thousands of years could help cells
wants to acknowledge that the discovery was made in improve modern agricultural livestock and breeding more science news
Greenland. programs, according to ... > read more

Professor Willerslev discovered the existence of the hair tuft Mobile DNA Elements In Woolly Mammoth In Other News ...
by coincidence after several unsuccessful attempts to find Genome Give New Clues To Mammalian Honda expands
early human remains in Greenland Evolution (June 9, 2009) — The woolly mammoth airbag recall as
died out several thousand years ago, but the more Toyotas
"I was speaking with the Director of the Natural History genetic material they left behind is yielding new probed
Museum in Denmark, Dr. Morten Meldgaard, when we started clues about the evolution of mammals. Scientists
discussing the early peopling of the Arctic," Willerslev recalls. Snow, wind batter
have now analyzed the mammoth genome ...
East Coast in big

http://www.sciencedaily.com/releases/2010/02/100210131948.htm Page 1 of 3
Waking the dead: Scientists reconstruct nuclear genome of extinct human being 2/10/10 2:28 PM

have now analyzed the mammoth genome ...


"Meldgaard who had participated in several excavations in East Coast in big
> read more
Greenland told me about a large tuft of hair, which was found 2nd storm
during an excavation in north-western Greenland in the Giant Bird Feces Record Pre-Human Iran says nuclear
1980's and now stored at the National Museum in Denmark. New Zealand (Jan. 13, 2009) — A fuel deal "still on the
treasure trove of information about pre- table"
"After the Greenland National Museum and Archives granted human New Zealand has been found in
permission, we analysed the hair for DNA using various Pakistan has
feces from giant extinct birds, buried beneath the
techniques and found it to be from a human male. For several "credible
floor of caves and rock shelters for thousands of ...
months, we were uncertain as to whether our efforts would be information" Mehsud
> read more
fruitful. However, through the hard work of a large dead
international team, we finally managed to sequence the first Ancient Retrovirus Is Resurrected Reuters
complete genome of an extinct human.," Willerslev says. (Mar. 1, 2007) — Retroviruses have been photographer says
around longer than humanity itself. In reborn after freed by
Willerslev adds: "It was crucial that a private person, Fredrik fact, the best-known family member, HIV, U.S.
Paulsen, chairman of the medical company Ferring, became is a relative youngster, with its first known human
interested in the project and provided the necessary funding Clashes erupt in Sri
infections occurring sometime in the ... > read
to run some pilot tests, and that The Lundbeck Foundation of Lanka over
more
Denmark, quickly followed up providing substantial economic general's arrest
support to complete the project." World First Discovery: Genes From Extinct Lebanon warns of
Tasmanian Tiger Function In A Mouse "dangerous"
"It shows how crucial private funding is to basic science these (May 20, 2008) — Researchers have situation with Israel
days. Without these private donors it would have taken us a extracted genes from the extinct Tasmanian
lot longer to sequence the first ancient human genome." Afghanistan says ready if thousands flee assault
tiger, inserted it into a mouse and observed a
biological function -- this is a world first for the use more top news
Blueprint of the ancient man
of the DNA of an extinct species to ... > read
The reconstruction serves as blueprint that scientists can use more
Copyright Reuters 2008. See Restrictions.
to give a description of how the pre-historic Greenlander,
DNA Extracted From Woolly
Inuk, looked -- including his tendency to baldness, dry
Mammoth Hair (Sep. 27, 2007) —
earwax, brown eyes, dark skin, the blood type A+, shovel- Free Subscriptions ... from ScienceDaily
Scientists discovered that hair shafts
shaped front teeth, and that he was genetically adapted to
provide an ideal source of ancient DNA
cold temperatures, and to what extend he was predisposed to Get the latest science news with our free email
-- a better source than bones and muscle for
certain illnesses. This is important as besides four small
studying the genome sequences of extinct animals. newsletters, updated daily and weekly. Or view
pieces of bone and hair, no human remains have been found hourly updated newsfeeds in your RSS reader:
They sequenced the entire ... > read more
of the first people that settled the New World Arctic.
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Willerslev's team can also reveal that Inuk's ancestors Despite Their Heft, Many
crossed into the New World from north-eastern Siberia Dinosaurs Had Surprisingly Tiny RSS Newsfeeds
between 4,400 and 6,400 years ago in a migration wave that Genomes (Mar. 8, 2007) — They
was independent of those of Native Americans and Inuit might be giants, but many dinosaurs Feedback ... we want to hear from you!
ancestors. Thus, Inuk and his people left no dependence apparently had genomes no larger than that of a
behind among contemporary indigenous people of the New modern hummingbird. So say scientists who've Tell us what you think of the new ScienceDaily --
World. linked bone cell and genome size among living we welcome both positive and negative comments.
species and then ... > read more Have any problems using the site? Questions?
"Previous efforts to reconstruct the mammoth nuclear genome
resulted in a sequence filled with gaps and errors due to DNA Ads by Google Your Name:
damage because the technology was in its infancy. The
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genome of Inuk is comparable in quality to that of a modern Better cancer diagnosis
human ," Willerslev tells and continues: Genome-wide copy number and LOH Comments:
"Our findings can be of significant help to archaeologists and Fresh or FFPE samples
others as they seek to determine what happened to people www​.i​Karyos​.com
from extinct cultures. Doing so requires organic material -- How to make electricity:
bones or hair kept as museum pieces or found at $198 homeowner's kit that power Co
archaeological sites. Previously, the DNA needed to have execs tried to outlaw in 18 states.
been frozen or buried in a layer of permafrost. But with the www​.​Power4​All​Homes​.com
new methods developed here at the Centre, that is not a Click button to submit feedback: Send It
premise anymore." University
Earn Your Graduate or Undergraduate
Much of the hands-on work analysing and joining the DNA Degree at our Accredited College.
sequences and the chemical analyses of what little was left of www​.​Amridge​University​.edu
the damaged genetic material together to form a complete
profile of Inuk was done by Morten Rasmussen. The work Human Resources Degree
was carried out in close collaboration with other scientists at Earn your bachelor's degree
the University of Copenhagen and in China, where they have with an emphasis in HR
far more sequencing machines than in Denmark. www​.​Marylhurst​.edu
"Not so long ago, reconstructing an entire modern human
genome took years," Rasmussen says. But the new methods
and the abundance of sequencing machines allow us to do it
in just a few months -- and that includes the time-consuming
task of analysing the results. The interesting thing about
compiling a human genome is that we can look at the genes
to see traits like why Scandinavians are blonde, why some
are predisposed to certain illnesses and why others more
easily become addicted to alcohol or tobacco. But the
genome we've reconstructed is no Frankenstein's Monster; it's
more like we've got the blueprints for a house, but we don't
know how to build it."
The results of the team's research will be published in the
leading British scientific journal Nature.

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Waking the dead: Scientists reconstruct nuclear genome of extinct human being 2/10/10 2:28 PM

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