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MCQ in Microbiology: Immunology Questions and


Answers with Explanation
NOVEMBER 27, 2012 BY TANKESHWAR ACHARYAIN MCQ IMMUNOLOGY, MCQ MICROBIOLOGY 3 COMMENTS

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1. Naturally acquired active immunity would be most likely acquired through which of the following processes?
a. vaccination
b. drinking colostrum
c. natural birth
d. infection with disease causing organism followed by recovery.
2. Which of the following convey the longest lasting immunity to an infectious agent?
a. Naturally acquired passive immunity
b. Artificially acquired passive immunity
c. Naturally acquired active immunity
d. All of these
e. None of these
3. Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule?
a. Antigen
b. Virus
c. Hapten
d. Miligen
e. Antibody
4. B and T cells are produced by stem cells that are formed in:
a. Bone marrow
b. The liver
c. The circulatory system
d. The spleen
e. The lymph nodes
5. B cells mature in the.. while T cells mature in the
a. Thymus/bone marrow and gut associated lymphoid tissue (GALT)
b. Spleen/bone marrow and GALT
c. Bone marrow and GALT/Thymus
d. Liver/Kidneys
6. Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?
a. T helper cells
b. B cells
c. Antibodies
d. Complement
e. T cytolytic cells
7. A living microbe with reduced virulence that is used for vaccination is considered:
a. A toxoid
b. Dormant
c. Virulent
d. Attenuated
e. Denatured
8. B cells that produce and release large amounts of antibody are called:
a. Memory cells
b. Basophils
c. Plasma cells
d. Killer cells
e. Neutrophils
9. The specificity of an antibody is due to
a. its valence
b. The heavy chains
c. The Fc portion of the molecule
d. The variable portion of the heavy and light chain
10. In agglutination reactions, the antigen is a
in precipitation reactions, the antigen is a
a. whole cell/soluble molecule
b. Soluble molecule/whole cell
c. Bacterium/virus
d. Protein/carbohydrates
e. Protein/Antibody

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MCQ in Microbiology: Immunology Questions and Answers with Explanation - micr...

11. B Cells are activated by


a. Complement
b. Antibody
c. Interferon
d. Memory cells
e. Antigen
12. Fusion between a plasma cell and a tumor cell creates a
a. Myeloma
b. Natural killer cell
c. Lymphoblast
d. Lymphoma
e. Hybridoma
13. Monoclonal antibodies recognize a single:
a. Antigen
b. Bacterium
c. Epitope
d. B cell
e. Virus
14. Cell mediated immunity is carried out by.. while humoral immunity is mainly carried out by..
a. B cells/T cells
b. Epitopes/Antigens
c. T cells/B cells
d. Antibodies/Antigens
e. Antibodies/Phagocytes
15. The ability of the immune system to recognize self antigens versus nonself antigen is an example of:
a. Specific immunity
b. Tolerance
c. Cell mediated immunity
d. Antigenic immunity
e. Humoral immunity

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1. Its the easiest MCQ in microbiology. You have to know only the definition of naturally acquired active immunity. Naturally
acquired active immunity is produced when the person is exposed to infectious agent. So the answer is d.
2. Active immunity can last a lifetime or for a period of weeks, months or years, depending on how long the antibodies persist.
So only one option in the choice contain active immunity as a part of answer. Answer is c
3. Hapten is a small molecule; they can act as antigen if it binds to a larger protein molecule. So the answer is c
4. This question asked you which stem cell is the immediate precursor of B Cell and T cell. The early development of stem
cell takes place in primitive tissue, late development in fetal liver and final development in bone marrow. So the answer is
a i.e. bone marrow.
5. Do you remember the sentence; T cells are thymus derived cell? If you can remember, you already solved this question. If
not you might remember differentiation of B Cell takes place in bone marrow and functional B cells are found in Gut
associated Lymphoid tissue (GALT). Yes the right answer is c
6. T cytolytic cell Tc cells and Natural killer cells kill infected host cells which are harboring intracellular pathogen. So answer
is option e
7. Attenuated means weakened. While making live attenuated vaccine the virulence of the microorganism is lost but its
antigenic characteristics are retained. The answer is d.
8. In this question definition is given and the word is asked. The definition of plasma cell is B Cell that is capable of producing
large amount of antibodies. So the answer is c

Try our dedicated MCQ Quiz section for Immunology.


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3 thoughts on MCQ in Microbiology: Immunology Questions and Answers


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March 23, 2015 at 9:05 am Edit

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November 20, 2015 at 2:44 pm Edit

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January 17, 2016 at 7:00 am Edit

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