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di waktu tidur). Penekanan asam malam hari tidak dapat dipertahankan dengan
dosis tidur antasid
Gastroesophageal Reflux
Antacids also may be useful to increase gastric pH and to increase lower esophageal sphincter
pressure in the management of esophageal reflux. The ACG states that antacids and
antirefluxants such as alginic acid are more effective than placebo in relieving symptoms of
heartburn induced by a meal, and are useful for self-medication as initial therapy for milder
forms of gastroesophageal reflux disease (GERD). However, suppression of gastric acid
secretion with a proton-pump inhibitor or histamine H2- receptor antagonist to control
symptoms and prevent complications of the disease is considered by the ACG to be the
principal therapeutic goal in the management of GERD. Other measures such as avoidance of
constrictive clothing, treatment of obesity, reducing meal size and dietary fat intake,
avoidance of foods that increase reflux, avoiding recumbency after meals, and elevating the
head of the bed should be initiated and continued throughout the course of treatment. For
further information on the treatment of GERD, see Uses: Gastroesophageal Reflux, in
Omeprazole 56:28.36.
Gastroesophageal Reflux