Fixative MOst COMmon - Neutral Buffered Formalin and Bouin's Fluid

Both of these cross link proteins, Thus maintaining a life-life image of the
tissue
MOst common coagulant fixatives
The alcohols - Methanol and Ethanol
Disruption of the tertiary structure of the protein changes their physical prope
rties
potentially causing insolubilitiy and loss of function.
Other examples of coagulant fixatives are picric acid, tricholoracetic acid
Several chemicals were selected as fixatives secondary to their potential action
s of
forming cross links within and between proteins.
Examples include formalydehyde, glutaraldehyde, metal salts