NHS Fetal Anomaly Screening Programme care pathway: Downs (T21), Edwards (T18) and Pataus (T13)

Screening for T21, T18 & T13

Women presenting in first trimester up

to 14+1 weeks of pregnancy

Women presenting between 14+2 to

20+0 weeks of pregnancy

Offer T21, T18/

T13 screening

Offer T21
screening only
(quadruple test)

Decline all

Accept T18/
T13 only

Accept all

Higher risk

Accept T21
only

Accept

Lower
risk

Lower risk

Offer 18+0 to 20+6 week

fetal anomaly scan

Higher
risk

Offer 18+0 to 20+6 week

fetal anomaly scan

Offer diagnostic
test

Accept

Affected by T21,
T18, or T13

Decline

Unaffected

Discuss options

Termination of
pregnancy

Offer follow-up
support

Continue with
pregnancy

Offer 18+0 to 20+6 week fetal

anomaly scan and follow-up at
birth

Public Health England leads the NHS Screening Programmes

Version 1.1

Decline

Offer 18+0 to 20+6 week

fetal anomaly scan