Académique Documents
Professionnel Documents
Culture Documents
- 33 -
- 34 -
Objectives
The objective of this guideline is to provide
evidence based recommendations to all categories of
health care workers, on work related infection risks and
safety measures to be adopted to minimize such risks.
List of Contributors
1. Dr. Sunethra Gunasena
2. Dr. Sepali Gunawardane
3. Dr. Sujatha Mananwatte
4. Dr. Pranitha Somaratne
5. Dr. Preethi Perera
6. Prof. Nilanthi de Silva
7. Prof. N.P. Sunil Chandra
- 35 -
Contents
Topic
No
2.1
- 36 -
Topic
Page No
36
38
43
44
2.1
47
2.6
2.7
2.8
Annexure
58
2.2
2.3
2.4
2.5
55
57
2.1.1
2.1.2
- 37 -
Placement evaluation
2.1.3
2.1.4
- 38 -
2.2
2.2.1
Recommendations
- 39 -
- 40 -
Agent
Hepatitis B
recombinant
vaccine
MMR
vaccine
Primary
schedule
& booster
(s)
2 IM
doses, 4
weeks apart
One dose
SC
Indication
Precautions
&
contraindications
Special
considerations
All HCW at
risk for
1. Prevaccination
screening is not
recommended.
2. Should be
tested anti-HBs
1- 2 months
after completion
of vaccination
Booster doses
not
recommended.
exposure
to blood or
body
fluids
(X)
Considered
for all
HCW who
lack proof
of immunity
No risk of
adverse
effects
Pregnancy is
not a
contraindication
1.Pregnancy
2. Immunocompromised
persons
3. Recent
administration
of
immunoglobulin
Varicella
Vaccine
Iry schedule
& booster(s)
Annual
vaccination
with current
vaccine
Administered
IM
Two (0.5 ml)
doses
SC 4-8 weeks
Indication
HCW who have
contact with patients
at high risk for
influenza or its
complications
HCW with no
reliable history of
C. pox or serologic
Precautions &
contraindication
Hypersensitivity
to egg protein.
Pregnancy,
*Immuno
compromised
Special
considerations
Recommended
in 2nd
& 3rd trimester
of pregnancy
BCG
vaccine
apart
evidence of
immunity
persons.
One ID dose
(0.3ml)
No boosters
Pregnancy,
*Immuno
compromised
persons.
Polio
vaccine
Rabies
vaccine
IM, SC or
Oral
according to
recommended
schedule of
manufacture
OPV
According to
recommended
schedule of
manufacturer
- 41 -
Tetanus &
Diphtheria
toxoid
IM 2 doses 4
weeks
apart & 3rd
dose 6
months later
(Td vaccine) Booster every
Meningo- years
coccal
I dose SC
vaccine
Abbreviations:
HCW in microbiology
laboratories who
handle
Salmonella typhi
(X)
Laboratory personnel
handling wild
Polio virus
(X)
- 42 -
Pregnancy
Use only
IPV for
Immuno
compromised
persons
frequency of
boosters
depend
on frequency
of
exposures
All adults
(X)
Pregnancy1st trimester
Laboratory
workers
handling
meningococci
(X)
Hypersensitivity
to any
component
As prophylaxis
in wound
Management
- 43 -
UI
UI
R
R
UI
UI
R
UI
R
UI
UI
R
R
UI
UI
R
UI
R
UI
UI
R
R
UI
UI
R
UI
R
UI
R
R
R
UI
UI
R
UI
R
C
UI
R
R*
C
UI
R
UI
R
UI
UI
UI
UI
UI
UI
UI
UI
UI
UI
UI
UI
Diabetes
C
UI
R
C
C
UI
R
UI
R
Renal failure
C
UI
R
C
UI
UI
UI
UI
R
Asplenia
HIV Infection
2.2.2
Alcoholic
cirrhosis
BCG
Hepatitis A
Hepatitis B
MMR
OPV**
IPV**
Pneumococcus
Rabies
Tetanus/
Diphtheria
Typhoid
(inactivated
Vi vaccine)
Typhoid
(Ty21a
vaccine)
Varicella
Pregnancy
Vaccine
Severe mmuno
suppression
*
**
- 44 -
Immunization of immuno-compromised
health care workers
Immuno-compromised
HCW
and
their
physicians should consider whether the benefits of the
vaccination outweigh the risks of being exposed to a
vaccine preventable disease and the risks of the
vaccination taken together.
Recommendations concerning immunization of
HCW with special conditions are given in Table-2.
2.2.3
Corticosteroid therapy
Persons
who
have
received
systemic
corticosteroids in excess of 20mg daily or every other
day for equal to, or more than 14 days should avoid
vaccination with MMR, its components or Varicella for
at least one month after cessation of steroid therapy.
2.2.4
Immunization records
contact of HCW
with patients when they have potentially
transmissible infections. It should cover,
1. Personal responsibility of using health
services and reporting illnesses
2. Work restrictions.
- 45 -
- 46 -
2.4
2.4.1
Diphtheria
2.4.2
Gastroenteritis
Pending their evaluation, exclude personnel with
acute gastrointestinal illness (vomiting or
dairrhoea, with or without nausea, fever or
abdominal pain) from contact with patients and
their environment or from food handling.
2.4.3
Meningococcal Disease
Immediately offer antimicrobial prophylaxis to
personnel who without the use of proper
- 47 -
- 48 -
2.4.5
2.4.4
2.4.6
Whooping cough
Immediately offer antimicrobial prophylaxis
against pertussis to personnel who have had
unprotected (without use of proper precautions)
intensive (close, face to face) contact with a
patient who has a clinical syndrome highly
suggestive of pertussis and whose cultures are
pending. Discontinue prophylaxis if results of
cultures or other tests are negative for pertussis
and the clinical course is suggestive of an
alternative diagnosis.
Exclude personnel in whom symptoms develop
(eg: cough> = 7 days, particularly if accompanied
by paroxysms of coughing, inspiratory whoop or
post-tussive vomiting) after known exposure to
pertussis, from patientcare-areas until 5 days
after the start of appropriate therapy.
2.5
Management of Accidental
Exposures to Blood and Body fluids
in Health Care Setting
2.5.1
Introduction:
- 49 -
- 50 -
C.
A.
A.
- 51 -
B.
C.
- 52 -
D.
E.
2.5.3.2
A.
- 53 -
B.
Follow up of HCW
2.5.3.3
A.
- 54 -
B.
Follow up of HCW
i. If the source is a known anti-HCV positive / at
high risk for HCV
If facilities are available check recipients
blood for HCV RNA at 6 weeks and at 12
weeks.
Check recipients blood for anti-HCV at
12 weeks, 24 weeks & at one year.
2.5.3.4
A.
Follow up of HCW
D.
C.
- 56 -
B.
- 55 -
2.6
Special Issues
2.6.1
Pregnancy
Management
2.6.2
- 57 -
- 58 -
2.7
References
1. Immunization
of
Health
Care
Workers.
Recommendations of the Advisory Committee on
Immunization Practices & the Hospital Infection
Control Practices Advisory Committee. MMWR
1997 (46) RR - 18
2. Updated US public health service guidelines for
management of occupational exposures to HBV,
HCV & HIV and recommendations for post exposure
prophylaxis. MMWR 2001 (50):RR -11
3. Guideline for Infection Control in Health Care
Personnel. American journal of infection control
1998 (26) 289 354
4. Hospital Infection Control Manual, Sri Lanka
College of Microbiologists 2005
5. General Circular No. 02-36/2001 of 12 March 2001
2.8
- 59 -
Annexure
Yes No
- 60 -