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 2015
)(
162 17.

liquid
x 18 .y

2
19
.



2
20

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(amu
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24
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 .
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10

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.:


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13


56
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58
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14


) (Aquilaria Malaccensis
60
.
mdpl 2400-0
34C-28 %80
mm/th 2000-1000
) (senyawa metabolit sekunder
)senyawa
61
.(aktif obat

simplicia
62.

: ) : 59 (2002
522-521 1.
60 P. Saikia dan M. L. Khan, Seedling Survival and Growth of
Aquilaria Malaccensis in Different Microclimatic Conditions of
Northeast India, Journal of Forestry Research, Vol.23, Issue.4,
. 574-569 ,2012
61 Eva K. Wollenberg, Incentives for Collecting Gaharu (FungalInfected Wood of Aquilaria Spp. Thymelaeaceae) in South
Kalimantan, Article of Economic Botany, Vol.55, Issue.3,
456-444 ,2001.
, dan , Nishi Muhan Nath, Sanjib Sarker, Md. 62
, Management and Economic Aspects of Growing
Aquilaria Agallocha Roxb. in Bangladesh, Articel of Small-Scale
Forestry, Vol.14, Issue.4, Desember 2015, 459-478.
15



63
.

64


Pseudomonas, Proteus, Micrococcus,

Bacillus
Streptococcus, Enterobacter
66
stainlss steel 65.E.coli
67
.

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16

%10
simplicia

68
karenoid flavonoid kuinon kurkuminod
69
. oven vakum
simplicia
.
simplicia
70
.



.
C 30-15 simplicia
71
.
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(Bogor : Pusat Penelitian dan Pengembangan Perkebunan, 2012),
17

 simplicia
73. 200 72
n-74
75
Etil Asetat Heksan

. 5372 rotary evaporator

.

76
.%9 %041 %198
cet.I, 68.
72 Badan Pengawas Obat dan Makanan, Peraturan Kepala Badan
Pengawas Obat dan Makanan Republik Indonesia Nomor
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76 World Health Organization, Research Guidelines for Evaluating
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18

 ) (+ %25
HCL dragendroff
) (+ FeCl31%
) (+

. FeCl31%
(+) triterpenoid

. ) (+ FeCl31%
10
77
.

gas chromatography-mass
) .spectrometry (GC-MS

viridicatin
)(2,7%
Asam Tanat (3,8%), Antosianin
(3,1%), Agarospirol (2,6%), Asam Fenolat
(4,3%), Onocerandiendion (5,2%) dan Asam
) Platyconic (2,4%
AUC
)(Area Under Curve
78
.y=a+bx
. in Vivo in Vitro
77 Le Van Thanh, Tran Van Do , Nguyen Huy Son, Tamotsu Sato
dan Osamu Kozan, Impacts of Biological, Chemical and
Mechanical Treatments on Sesquiterpene Content in Stems of
Planted Aquilaria Crassna Trees, Journal of Agroforestry Systems,
Vol.89, Issue.6, Desember 2014, 973-981.
19

disc
.MHA diffusion
Escherechia Coli
Staphylococcus
Mutans,
Staphylococcus
Pseudomonas Aerogenosa Aureus

l 20 ppm 100 75 50
Mueller Hinton
. 24 C 37

79
.

triterpenoid
MSU (onocerandiendion)
P1 P3 P2 ( p0,05)
( p0,05) P4
.
78 Nguyen Thanh Dong, KiHwan Bae, Young Ho Kim, Gwi Seo
Hwang, Ok Soon Heo, Se Eun Kim, Jong Seong Kang, Quantitative
Determination of Psoralen and Angelicin from some Medicinal
Herbs by High Performance Liquid Chromatography, Journal of
Pharmaceutical Research, Vol.26, Issue.7, Juli 2003, 516-520. dan
Yanhong Xu , Zheng Zhang , Mengxi Wang , Jianhe Wei , Hongjiang
Chen, Zhihui Gao, Chun Sui, Hongmei Luo dan Xingli Zhang,
Identification of Genes Related to Agarwood Formation:
Transcriptome Analysis of Healthy and Wounded Tissues of
Aquilaria Sinensis, Journal of Central South University, Vol.20,
Issue.8, Augustus 2013, 2115-2123.
79 C. Thornsberry dan R. N. Jones, Cefoperazone: Spectrum of
Antibacterial Activity and Disc Diffusion Testing, Journal of
Microbiology, Vol.22, Issue.1, November 2012, 3-12.
20

 (LD50) %50

" "
).(antiinflamasi


.
.mg/kgBB 500
platyconic
pancreas langerhans
.
. pancreas
quiescent
80
.
.


.
antibiotik,
)antasida,antiinflamasi,
antidepresi,
antioksidan,
(antihistamin,antidibetes
) (Aquilaria Malaccensis

)(
80 Zhenzhong Yang, Linli Wang, Feng Zhang dan Zheng Li,
Valuating the Antidiabetic Effects of Chinese Herbal Medicine: Xiao-KeAn in 3T3-L1 Cells and KKAy Mice Using Both Conventional and Holistic
Omics Approaches, Article of BMC Complementary and Alternative
Medicine, Vol.12, Issue.1, Desember 2015, 267-272.

21

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)
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22