Mecanismo de accin de

la Transcriptasa
Reversa

Characteristic

Effect(s)

Retrovirus with a genome that consists of

two copies
of +ssRNA

Reassortment of viral genes possible;

reverse transcription produces much
mutation
and thus genetic variation; genome
integrates into hosts chromosome

Targets helper T cells especially, but also

macrophages, dendritic
cells, and muscle cells, and possibly liver,
nerve, and epithelial cells

Permanently infects key cells of hosts

immune system

Antigenic variability

Numerous antigenic variations due to

mutations helps virus evade hosts immune
response

Induces formation of syncytia

Increases routes of infection; intracellular

site helps virus evade immune detection

Epidemiologa en Argentina

Marcadores Diagnstico