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developmental genetics
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Male bird: ZZ
Male drosophila: XO
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Male mammal: XY
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Female bird: ZW
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Rescue protocol: When several genes have similar mutant phenotypes, sequences of action and expression
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Spontaneous mutation: Addition, subtraction, deletion or substitution of DNA including the addition of transposable elements
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Stella gene: Present in mouse, encodes a chromosmal protein expressed in germ cells and early embryo blastomeres, if knock out the
mother is normal but with fefective embryos
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Temperature sensitive mutation: Dependant on temperature, heat causes conformational changes to proteins products
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Transgene or knockin: Gene introduced into an organism through transgenesis, has promoters
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White gene: Gene of the drosophila that influence the production of rd eye pigmanet, when lost a white eyed animal is produced (loss of
function)
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Zinc finger nucleases: Artificial proteins constrcted uding a judicious selectionof zinc finger type DNA binding domains combined with an
endonuclease