BIO 301 (rev 5 Feb 2014)

Spring Session 6, 3 Credit Hours (12 May 2014 19 June 2014)

School of Natural Sciences- KCC 144
4:10 pm 5:50 pm MTWR
BIO 301-S6:

Pathophysiology

CREDITS:

3 credits

DESCRIPTION:

This course is designed to introduce mechanism and manifestation of different

human diseases as related to changes in physiologic function. This basic
science of pathology is concerned with the etiology and pathogenesis of
disease. Essential information is provided for understanding the diagnosis of
disease in the clinical setting.

PREREQUISITE (S):

Required: BIO 261, 262, 263, 264 - Anatomy and Physiology, CHEM 106
Chemistry for Allied Health or permission of the instructor
Recommended: BIO 256, 257- Microbiology

COREQUISITE (S):

None

TEXT:

Robbins Basic Pathology, 9TH ed, Kumar, Abbas, and Aster, Elsevier
Publishing, 2013. ISBN: 978-1-4377-1781-5.

FACULTY

Russell E. Moore, B.S., M.S.

KCC 139
Phone: 473-4454
E-mail: rmoore04@spalding.edu
Office Hours: by appointment

I will be available immediately before class for questions. Most days I will be in my office from
approximately 2:00 pm to 4:00 pm. I have fairly full schedule this term, so appointments will be best. If you
have a question during the lecture, please ask it. Someone else may have the same question. If you are
having trouble with the material, do not wait too long to come and see me. This course moves very quickly
and it will be difficult to catch up if you fall behind. THE BEST WAY TO REACH ME
IS BY E-MAIL (rmoore04@spalding.edu). I WILL CHECK IT OFTEN AND GET BACK TO YOU ASAP.
COURSE ATTENDANCE POLICIES: Consult Spalding University Catalog as needed. One word of
caution this is an intense course. Absences from lecture will only serve to reduce your overall performance
in the class. Therefore, it is important that you make every effort to be present for every class. However,
students should note that they may miss UP to 6 (six) classes; however, any absences more than 6 will result
in a grade of F for the course. Students should make every effort to arrive on time to class and to stay for
the entire class period. Students should also note that leaving class early or coming late to class may be result
in being charged as absences.
COMPETENCY OUTCOMES: : Upon completion of the course, the student will be able to:
1. Describe the structures and functions of each physiological system
2. Relate the normal body functioning to the physiologic changes that participate in disease production
and occur as a result of disease

3. Synthesize the pathophysiological processes of acute and chronic health problems.

4. Differentiate between effective and ineffective physiologic responses to internal and external
stressors
5. Differentiate between modifiable and non modifiable risk factors in the development of pathological
processes.
6. Critically evaluate the importance that research has in the discovery of new interventions that disrupt
the pathophysiological process of selected diseases.
TOPICAL OUTLINE: See below
LEARNING STRATEGIES:
Classroom discussion, assignments, case studies, and assessments
UNIVERSITY STUDIES COMPETENCIES
To graduate with either an associate or bachelor degree, Spalding University requires undergraduate students
to fulfill a specific number of semester hours in the humanities, natural sciences and mathematics, social
sciences, religious studies, and communication. These general education requirements comprise the
University Studies component of all undergraduate degree programs.
In keeping with Spalding Universitys long tradition, rigorous study across and within the academic
disciplines fosters a commitment to life-long learning, service, and the promotion of peace and justice among
students and faculty. University Studies courses are designed to give students opportunities to practice habits
of mind and heart that emphasize the joy of discovery, animate the creative intellect, and promote the
development of personal and intellectual competencies needed for success in any chosen profession.
To this end, students will evidence the ability to:

Think critically;
Communicate effectively using oral, visual, and written skills;
Comprehend social issues from different perspectives such as literary, artistic, historical, cultural,
philosophical, scientific, global, political, technological, and economic;
Use scientific and mathematical skills to solve problems;
Demonstrate effective interpersonal skills; and
Understand ones personal values and religious beliefs and respect those of others.

The following Objectives are the specific University Studies Competencies that will be
developed in this course. The Outcomes state ways in which those objectives are to be
met in this course.
OBJECTIVES:

OUTCOMES:

To think critically

Regular class participation related to

readings and homework assignments;
completion of exams

To communicate effectively using oral,

visual, and written skills

Class discussions, case studies and other

assessments.

To comprehend social issues from different

Regular class participation; successful

completion of exams, quizzes and other

perspectives such as literary, artistic,

historical, cultural, philosophical,
scientific, global, political, technological,
and economic

assessments

To use scientific and mathematical skills to

solve problems

Successful completion of assignments,

quizzes and exams.

To demonstrate effective interpersonal

skills.

Maintaining a respectful learning

environment in the classroom by
following fundamental rules of courtesy.

To understand ones personal values and

religious beliefs and to respect those of
others

Maintain a respectful learning

environment, particularly when topics
involve personal views and religious
beliefs that may not be those of your
own.

ASSESSMENT OF OUTCOMES:
Written examinations (450 points): The course grade will be based on several assessments,
among these are three in class exams worth 150 points each. There are NO MAKE-UP EXAMS.
A missed exam will count as a zero. However, there are some cases where a student may miss an
exam for a justifiable cause. Students should inform the Instructor as soon as possible AND
provide some evidence (such as a doctor's note). If you must miss an Exam for a legitimate
reason, please inform the Instructor as soon as possible, preferably before the Exam. In order to
be able to make up a missed Exam, the Instructor must be notified no later than the day of the
Exam. All make up exams will be held on WEDNESDAY 18 JUNE 2014. Exams may be
constructed using multiple choice, fill in the blank, short answer, matching, and/or free response
style questions. Exam dates will be:
Exam 1 THURSDAY 22 MAY 2014
Exam 2 THURSDAY 5 JUNE 2014
Exam 3 - THURSDAY 19 JUNE 2014

Quizzes (60 points): There will be three quizzes, each counting 20 points. The lowest quiz
grade will be dropped. Should a student be absent the day a quiz is administered, this will
count as the students dropped quiz grade. Students absent for more than one quiz will receive
a grade of zero for the second missed quiz. Quiz dates will be:
Quiz 1 TUESDAY 20 MAY 2014
Quiz 2 TUESDAY 3 JUNE 2014
Quiz 3 TUESDAY 17 JUNE 2014

Assignments (80 points): Students will complete 2 take home assignments each worth 40 points.
These assignments must be word processed and double-spaced and are due on dates shown
below and must follow the directions and parameters set for each assignment. Note that all
written responses will but submitted to TURNITIN for plagiarism. Students found to be in
violation of plagiarism will receive a grade of zero for the assignment and will be assigned to
meet with the Chairperson of the School of Natural Sciences before being permitted back into
class.
o Assign 1 May 20
Assign 2 June 2

Attendance (10 points): Points will be awarded to students for their attendance to class. Students
missing no days of class and always being on time to class will receive 10 points for attendance.
Students missing or being late to class once during the six weeks will receive 8 points. Students
missing or being late twice during the six weeks will receive 6 points. Students missing or being
late to class more than twice will receive no points for attendance.
Exams
Quizzes
Assignments
Attendance
TOTAL POINTS

450
60
80
10
600

Grades:
588 600 points
540 587 points
480 539 points
420 479 points
360 419 points
< 360 points

98 100%
90 97%
80 89%
70 79%
60 69%
0 59%

A+
A
B
C
D
F

The university policy of academic status and appeals is available in the University catalog under General
Information, Procedures for Student Complaints and Grievances, Academic Issues. Please note you have five
business days to begin this process.
ADA STATEMENT:
Any student who, because of a disability, may require special arrangements in order to meet course
requirements should contact the faculty as soon as possible to make such accommodations as may be
necessary. Students should provide written verification of the need for such accommodations from the
Office of Student Life and Development
ACCESSABILITY STATEMENT:
In keeping with Spaldings Mission statement our community of faculty, staff and students is diverse. This
brings a richness to our campus and, more importantly, to our classrooms. Spalding University recognizes
and respects individual differences in our educators and our learners. Any student who requires academic
assistance for documented learning or health issues, should contact the Director of Student Support Services
in the Academic Resource Center. Registering with the Office of Student Support Services, by the student,
in a timely manner is critical. Accommodations are not retroactive. The Academic Resource Center is
located in ELC 200 (Phone: 502 873-4169).
ACCESSIBILITY IN OUR LEARNING ENVIRONMENT:
Your academic progress in this class is important. If you are aware of a life circumstance that may affect
your academic performance please let me know as soon as possible. If, during the course, you encounter any
obstacle please discuss this with me immediately. Once these hindrances are disclosed we can work together
to develop strategies to overcome them.
This class seeks inclusion for all participants. Individuals with documented academic differences of any kind
(including learning differences, ADHD, depression, health conditions) who require instructional, curricular,
or test accommodations are responsible for making such needs known to the instructor as early as possible.
First, you must be registered with the Director of Student Support Services. The director will request

documentation confirming your need for academic accommodation and a completed application for
Accessibility Services. Contact information for the Director of Student Support Services is as follows:
Kelly Cogar (kcogar@spalding.edu) ELC 200 (Phone: 502 873-4161).
ACADEMIC POLICIES:
The current Spalding University Catalog delineates pertinent academic policies including academic and
professional integrity. The Catalog is available on-line @ www.spalding.edu. Each student is responsible
for compliance with these policies and procedures.
COURSE WITHDRAWAL DATES AND FINANCIAL AID INFORMATION:
The last date to drop this class is 16 MAY 2014 and the last date to withdraw is 6 JUNE 2014. Specific
course withdrawal information is available from the Office of the University Registrar. Be certain to contact
the Office of Financial Aid and speak with your counselor before withdrawing from any class as this may
impact your financial aid status.
ONLINE COURSE EVALUATION:
The course evaluation will be done online. You will receive information from IT toward the end of the course
as well as reminders to do the evaluation. You have up to two weeks after class to complete the evaluation.
CLASS ROOM RULES:
1. Under NO circumstances are telephones permitted to be out or used during class. Students are expected to
turn OFF all telephones prior to the start of class.
2. Lab tops, iPads, and similar devices may be used; however, students using them are expected to follow
proper usage etiquette in the classroom so as not to distract other students. This means focusing on class
materials and NOT surfing the net, checking email, shopping, etc. It is also expected that students with these
devices should find seats towards the rear of the classroom so as to minimize distractions. Should these
policies become problems, students may lose these privileges at the instructors discretion.
3. Do not get up to leave class unless it is an emergency. A 10 minute break will be given approximately 90
minutes after the start of class (midway). If you know in advance that you will be leaving early, please take
an aisle seat close to the front of the room so as to minimize distractions when you leave. Also, if you arrive
to class late, please take the seat CLOSEST to the door so as not to add to the distraction of you coming into
class. If desired, you may find a different seat on the break midway through the class.
4. Talking or other disruptions during lecture will not be tolerated. If you did not understand or the
presentation is too fast, ASK A QUESTION.
5. It is Spaldings policy NOT to allow children into the classroom. This is of particular necessity in a class
such as this one. We will be viewing images that are not appropriate for young eyes and minds. Therefore,
under NO circumstances will individuals of any age other than the students registered be permitted to
attend the class.
6. Assessment procedures will be covered in class prior to the administration of assessments.

ATTENDANCE:
Students are expected to attend each class and to arrive at class ON TIME! This is a large class and when
students are late, distractions occur that can be detrimental to the learning of others. Attendance is taken and
recorded for each class meeting. Students having more than 6 absences in the session will receive a grade
of F for the course. Please note that tardies to class and leaving class early BOTH constitute absences
from class and will be recorded as such! Since attendance is quite important, should you be late to class, it
is the students responsibility to inform me either at the break or after class that they had come in after
attendance had been taken so that they can receive credit for having come to class.
ACADEMIC DISHONESTY:

As stated in the University Catalog, all students are expected to adhere to the highest standards of academic
integrity. The School of Natural Sciences affirms and supports the goals and standards regarding academic
integrity that are delineated in the University Catalog. Students, faculty, and staff are referred to the
University Catalog for a detailed discussion on the characteristics of academic integrity, as well as a list of
activities that are construed as academic dishonesty.
When a faculty member becomes aware of academic dishonesty, he or she becomes responsible for initiating
procedures that are outlined in the University Catalog. These procedures include an investigation into the
matter, a meeting with the student, and a written report. The University Catalog also includes procedures for
an appeal by the student should they not agree with the findings of the investigation and/or the sanction
imposed by the faculty member. In accordance with the University Catalog, the School of Natural Sciences
has adopted a no tolerance policy for acts of academic dishonesty that include the sanctions listed below.
SCHOOL OF NATURAL SCIENCES SANCTIONS FOR ACADEMIC DISHONESTY:
First violation: A failing grade of zero for the particular assignment in question; notification of Chair in
students major
Second violation: A failing grade for the course; notification of Chair in students major
Third violation: Expulsion from the School of Natural Sciences (if applicable), or contact with the Chair in
the students major and the Athletic Director (if applicable)
The Chair shall ensure that any violations and the appropriate sanctions are kept in an official confidential
record in the School.
ONE FINAL NOTE:
In this class you will be given what may seem an enormous amount of information. With this in mind it is
VERY important that you not get behind! Please address questions you may have early and do not hesitate to
email me if you have questions outside the classroom. This is also a discussion-rich course and students are
expected to participate in classroom discussion of topics presented. Discussion enhances learning for
everyone and certainly makes the class more interesting!!
DISCLAIMER: I reserve the right to change or modify this syllabus should exigent circumstances prevail
(snow days, ice days, power outages, etc).

TOPICAL OUTLINE:
Section 1: An Overview
Health in History
0. Introduction to Pathophysiology
Pre-test
Section 2: Basic Disease Processes
1. Cell Injury, Cell Death and Adaptations
2. Inflammation and Repair; Regeneration and Healing
3. Hemodynamic Disorders
4. Diseases of Immunity
Section 3: Neoplasia and Genetics
5. Neoplasms I and II
6. Genetic and Pediatric Disorders
Section 4: Environmental
7. Environmental and Nutritional Disorders
8. Infectious Disease
Section 5: Cardiovascular and Pulmonary Disorders
9. Blood vessels
10. Heart
11. Hematopoietic and Lymphoid Tissues
12. Lung
Section 6: Excretory, Reproductive and Endocrine System Disorders
13. Kidney and its Collecting System
17. OMIT
18. Female Genital System and Breast
19. Endocrine System
Section 7. Organs and Accessory Structures of the Digestive Tract Disorders
14. Oral Cavity and GI Tract
15. Liver, Gallbladder and Biliary Tract
16. Pancreas
Section 8: Skin, Muscle and Nerve Disorders
20. Bones, Joints, and Soft Tissues
21-22. PNS, Muscles, and CNS
23 Skin