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IEEE Trans Biomed Eng. 2016 Feb;63(2):438-48. doi: 10.1109/TBME.2015.2463283.
Epub 2015 Jul 31.
Early Warning of Acute Decompensation in Heart Failure Patients Using a
Noncontact Measure of Stability Index.
Javed F, Farrugia S, Colefax M, Schindhelm K.
Abstract
OBJECTIVE:

Hospitalization due to heart failure (HF) continues to be a major clinical and


economic challenge. To reduce hospitalization, this paper proposes a novel home
telemonitoring system for an early warning of acute decompensation in patients
with chronic stable New York Heart Association class II-IV HF.
METHODS:

It is based on deriving nocturnal respiratory related time series using a noncontact


radio-wave bio-motion sensor. The system generates an alert when there is a

change in the underlying probability distribution of the time series which can be
regarded as a surrogate marker of patient stability.
RESULTS:

The system's performance is evaluated using dual-site longitudinal data collected


from 104 HF patients over 12-24 months. The system reported an average
sensitivity of 0.62 to detect a change during an episode of acute decompensation
and an average specificity of 0.67 on the blind validation set, when the frequency of
alert was four weeks. The system also performed well to predict acute
decompensation with an average sensitivity of 0.55 and specificity of 0.73 on the
validation set, where an event window was defined as three weeks preceding an
event.
CONCLUSION:

These results demonstrate that the design and implementation of such a system is
a positive step toward developing noncontact systems capable of preventing acute
decompensation, reducing readmissions to hospital and ensuring better quality of
life for HF patients.

PMID:
26258931

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