QUANTITATIVE DETERMINATION OF

ACETYLSALICYLIC ACID IN ASPIRIN TABLETS BY

BACK TITRATION
K.C. GARBIN
DEPARTMENT OF CHEMICAL ENGINEERING, COLLEGE OF ENGINEERING
UNIVERSITY OF THE PHILIPPINES, DILIMAN, QUEZON CITY, PHILIPPINES
DATE PERFORMED: SEPTEMBER 27, 2016
INSTRUCTOR: KYLE BENITO
1. Discuss the precautions in
preparation of KMnO4?
Because
KMnO4
has
high
oxidation number, it is extremely
reactive to light. In order to
prevent KMnO4 from reating with
light, every glassware that will
contain KMnO4 must be wrapped
with aluminum foil or carbon
paper to prevent the light from
reaching
KMnO4.
This
also
includes the burette tht will be ued
for the titration.
2. What is the significance of
blank titration?
In this experiment, KMnO4 was
expected to only react with
oxalate. It must not react with
other chemicals mixed with oxalate
in the analyte solution but the
permanganate do react with other
chemicals in the analyte solution.
In order to remove this error, a
solution with all the required
chemicals except the analyte must
be preapred. This will then be
titrated with permanganate and
the molarity of KMnO4 derived
here will be subracted from the
molarity of KMnO4 derived from
the analyte solution and this will
give the real molarity of KMnO4
3. Discuss the titration with self
indicator and its advantages.
A titration with self indicator
means that an additional chemical
that detects the change in solution

is not needed. The indicator in this

kind of titration will be provided by
the chemicals involved in the
reaction.
Titration
with
self
indicator is useful in titration of
solutions that does not have acidity
or basicity. It also reduces the
error in the results because adding
an external indicator will slightly
change the concentration of the
solution.
4. What is the importance of
boiling KMnO4 solution if it is
stored for future use
AThe magnesium ions detach from
EDTA and combine with EBT,
producing a red color. After
titration, the magnesim ions go
back again to the EDTA creating a
blue solution.
5. What is the purpose if heating
the oxalate mixture to 70 80C before titrating it with
KMnO4?
It is useful in preservng food and
also
i
preserving
biological
samples such as blood
6. Explain the rationale behind
using H2SO4 to acidify the the
analyte mixture instead of
using HCl?
A large formation constant was
needed for the Ca and Mg ions to
react with the EDTA. The lower the
number of pH, the leser the
formation constant becomes. The

pH must be >pH8 to have someReferences

desirable results.
[1] Skoog, D.A., West, D.M., Holler, F.J.
7. Discuss the possible sources ofFundamentals of Analytical Chemistry.
error and their effects on theSaunders College Publications, New
York. 1988.
calcuated parameters.
T