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ABSTRACT: Forty-eight (48) consecutive patients seeking treatment in a referral based practice for
complex chronic painful temporomandibular joint (TMJ) disease were enrolled in a prospective study to
assess specific symptom relief from anterior repositioning appliance (ARA) therapy and the relationship
between specific symptom relief and the status of the TMJ disk. Each patient was assessed on 86 symptoms based upon whether each symptom was present before treatment and absent, better, unchanged
or worse after Maximum Medical Improvement (MMI). The most common symptom was occipital cephalalgia (94%). The least common symptom was pain and burning of tongue (8%). A profile of a temporo-
0886-9634/2302089$05.00/0,
THE
JOURNAL OF
CRANIOMANDIBULAR
PRACTICE,
2005
by CHROMA,
Inc.
Copyright
Manuscript
received
received
6, 2004; accepted
13, 2005
mandibular disorder (TMD) patient was developed. The typical TMD patient has cephalalgia, mainly in
the occipital, temporal and frontal region, pain upon chewing food, pain upon opening and closing the
mouth, TMJ pain, pain in the back of the neck and difficulty chewing food. Before treatment, patients with
bilateral displaced disks had more symptoms than those with unilateral displaced disks and the opposite
side normal. After MMI, the maximum benefit (percent of pretreatment symptoms relieved) was found in
patients with normal or recaptured disks. The minimum occurred in patients whose disks did not recapture with therapy. ARA therapy improved or eliminated symptoms in all patients in the study.
37203
E-mail: hcstmj@aol.com
Thisappliance
article (ARA)
reportstherapy
on the
of the
andcontinuation
its effect on patients
with craniofacial pain and temporomandibular disorders
(TMD).1,2 Symptom relief has been described in a general
sense by Fricton, et al,3 and Dworkin, et a1.4 The ability to
relieve specific symptoms of craniofacial pain in TMD
patients has not been reported. The visual analog scaleS
(V AS) is a popular method of evaluating pain. The
patient is instructed to rate pain on a scale of 0 to 10 with
no pain at 0 and the worst pain imaginable at ten points.
This method can be customized to address specific symptoms, but it is time-consuming and is thus not typically
used among research subjects to evaluate more than a
few symptoms.
The TMJ Scale6,7 is a proprietary quantitative and qualitative assessment of patient symptoms from TMJ disorders and includes pain evaluation. A few studies have
been published that used the TMJ Scale to rate symptom
improvement at treatment completion.8,9 Specific symptoms have been tracked but outcomes for specific symptom improvement were not given.
The purposes of the present study were: 1. to determine
the effect of ARA therapy on specific symptoms in TMD
89
ARA THERAPY
RELIEF
SIMMONS
AND GIBBS
Table 1
Patients Who Did Not Reach
and Methods
Patients
Fifty-eight (58) consecutive patients seeking care in a
referral-based practice for complex chronic craniofacial
pain and TMD were recruited for the study. Criteria for
inclusion were chronic temporomandibular pain and dysfunction by history and examination, age at least 18
years, and informed consent. Exclusion criteria were
inability or unwillingness to undergo magnetic resonance
imaging (MRI) (such as implanted electronic devices,
claustrophobia, etc.) and pregnancy. Forty-eight (48)
patients completed initial therapy and are reported on
here. Ten withdrew from the study for the reasons shown
in Table 1. Six of the ten were doing well but elected to
stop treatment for a variety of reasons. The other four terminated before sufficient treatment time to achieve significant symptom reduction. It is extremely unlikely that
these departures biased the results of the study. There
were 47 female participants and one male. The mean age
of participants at appliance delivery was 38 years. The
youngest was 18 and the oldest was 67.
The protocol was approved in advance by the Institutional Review Board of Vanderbilt University. Informed
consent was obtained from each patient before entry into
the study.
Treatment
Maxillary and mandibular anterior repositioning appliances were constructed for each patient. The mandibular
appliance was worn whenever the patient was awake,
e.g., eating and speaking. The maxillary appliance was
worn whenever the patient was reclined for more than an
hour and during sleep. The maxillary appliance had a
ramp that extended lingual to the mandibular incisors to
hold the mandible either open or protruded while the
patient was reclined. The patients were instructed to leave
one appliance in during teeth brushing while brushing the
opposing dental arch. One appliance was, therefore, in
the patient's mouth 24 hours a day. There is a consensus
in the literature supporting the use of dual appliances on
the same patient in ARA therapy with the wearing schedule described.5,lo.12 The ARA established the treatment
position for the condyles in the fossae as the Gelb 4/7
position,I,13 which is its normal position, as published by
recognized authorities.14.16 This position was derived by
first determining the location of the condyles on cephalometrically corrected tomograms in relation to the Gelb
90
PRACTICE
SIMMONS
II
II
II
\1
~
I,
It
II
i
I
I
I;
II
:1
II
I~
II
1\
II
II
::
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i
i
AND GIBBS
ARA THERAPY
RELIEF
Analysis
PRACTICE
91
ARA THERAPY
RELIEF
SIMMONS
AND GIBBS
Table 2
Symptoms Surveyed in 48 Patients
Pre-Treatment Symptoms VS. Symptoms After Maximum Medical Improvement
(Number of Patients/% of Total)
L
R
L
0/0
44/92
14/32
L
R
R
R
AfterMMI
4/18
2/12
3/14
15/88
0/0
1/3
17/35
19/76
18/78
2/9
1/4
13/35
24/65
31/67
25/68
29/66
1/2"
6/24
40/83
0/0
1/25
3/75
3/75
2/9
19/86
1/5
33/73
45/94
6/23
26/54
20/77
1/6
0/0
18/38
24/69
15/37
24/55
40/83
24/60
17/39
27/71
19/61
Better
Worse
Absent
3/10
2/7
12/30
12/39
3/8
1/3
4/21
3/12
24/60
14/74
20/63
20/67
20/69
36/75
21/66
28/76
29/60
3/17
14/74
10/31
4/1
2/7
19/40
30/63
4/11
2/6
1/6
19/50
3/9
10/27
8/23
5/20
1/4
1/2
2/13
20/71
27/82
13/81
19/76
26/63
0/0
20/80
17/49
4/12
12/67
7/19
4/16
35/73
10/29
43/90
26/70
18/38
34/71
25/52
8/89
32/74
5/28
1/6
3/9
6/17
18/47
10/28
3/8
24/67
14/37
25/52
35/73
33/69
36/75
9/30
1/3
19/63
19/86
18/82
46/96
37/77
14/34
5/20
3/13
0/0
0/0
27/66
23/48
28/58
0/0
0/0
4/8
1/25
1/2
22/46
2/5
20/45
25/61
14/35
27/61
1/2
41/85
1/17
18/100
0/0
5/83
6/13
27/68
11/31
1/3b
2/11
10/31
10/24
5/26
29/71
21/84
18/58
13/68
32/66
26/72
6/21
0/0
30/63
19/40
1/5
13/72
3/16
2/5
8/22
6/16
8/27
1/4
8/17
27/56
32/66
31/65
11/35
13/33
8/21
2/5
24/62
38/79
39/81
31/65
16/39
10/29
3/30
8/29
27/73
5/15
27/77
7/70
20/57
29/85
16/42
15/43
2/6
20/57
3/10
27/90
30/83
37/77
10/23
3/8
1/11
9/19
3/9
2/6
42/88
38/79
10/21
1/2"
14/30
4/825/52
I12/30
I11/24
4/22
2/25
5/31
5/19
41/85
1/3
0/0
1/6 Pretreatment
16/33
21/78
10/63
I 13/72
6/75 44/92
I 18/38
Symptom
Same
92
PRACTICE
SIMMONS
AND GIBBS
ARA THERAPY
II
RELIEF
II
14/39
4/11
18/50
18/42
2/5
13/59
23/56
2/5
1/2
2/7
12/35
1/20
9/26
1/20
6/18
5/14
5/15
19/56
112
5/15
24/73
0/0
32/74
1/3
2/6
2/9
1/2
15/38
7/32
21/54
22/51
22/47
1/5
12/54
35/73
20/57
16/39
1/3
1/5 I 11/26
9/33
16/59
17/49
0/0
3/60
13/37
17/50
1/5
1/3
7/32
12/34
0/0
41/85
0/0
319"
3/9
16/74
12/39
15/44
Pain-nape
36/75
34/71
33/69
22/47
39/81
27/56
35/73
43/90
43/90
5/11
I 31/65
17/5534/71
Ii
II
ii
II
l
_J
aneck injury
bnot related
Cpregnant
I
I
l
If'
I~
Jj
I,
Ii
Ii
/i
PRACTICE
93
ARA THERAPY
SIMMONS
RELIEF
AND GIBBS
Table 3
Disk Status at MMI
VS.
11
N25
57
33
43%
52%
23
35
49%
N61
33
N43
0MlWOR
36
31
85%
33
076
54
029%
0 of
33%
89%
45
78%
54
49
58%
ALIWOR
N
ALIWOR
57
36
N
60
031
71
44
36%
67%
41%
54%
40%
59%
97%
AMlWOR
N24
33
833%)
82
38
69
56
31
76%
98%
1016%
20
62
515
2N
31%)
51
N46
48%
77%
AlWR
N57
1652%
48
43
1423%0
62
47
59
62
39%
84%
82%
46%
AMlWOR
LARIWR
2339%
AJWR
716%
818%
67
37
59
68
67
046
60
92%
100%
53%
AMIWR
AMlWOR
N80
AlWR
71
33
48
47
50
25
77
64
91%
65
28%
912%
21
6788%
76
56%)
AlWOR
AlWR
AlWOR
AlWR
51%
AMIWR
ALIWR
M!WR
75
M!WR
MARJWR20
A.LIWR
436
AlWR
40N
AlWOR
61%
AlWOR
16(26%)
N
N
MARlWOR
23
AMlWOR
AlWOR
AlWOR
M!WR41
MARJWR
MlWOR
A.LIWR
5(6%)
1(1%)
MlWOR
A.LIWR
AlWR
A.LIWOR
A.LIWOR
MARlWR
MAWWR
5(11%)
MAR!WR
2(3%)
2(3%)
64%)
1(premant)(1
13%)
8(10%)
27
%
) Post3(6%)
12(15%
AlWOR
68
LARIWR
'72%
1428%
AJWR
3Number
00N
8(15%
4685%
15
25
22%)
39%)
29(51%)
25(
26
1(premant)(2%)
49%)
40
30
1000/.)
12%)
39
29%)
3(sinus)(6%
10(22%)
) )Post100%)
13(22%)
21(33%)
2145%
6(9%)
12(neck)(16%
48
1(3%)
3151%)
9(15%)
2(4%)
3246%)
8(21%)
16
37
48%)
19
9(16%)
9(15%)
12
919%
6(8%)
1(2%)
38
19
13
28
51
43
0644
3(7%)
47
47
28(58%)
43
59
41
5(lIremant)(1
0%)
1950%
11
36
27
37
59%)
11(19%)
26(63%)
12%)
11(23%)
Status
PreSame
Better
Absent
Worse
PostNumber
Disk
Disk
Number
ofof
of
Left
MMI(%)
Symptoms
Symptoms
Symptoms
MMI(%)
Right
MMI(%)
N - Normal, A - Anterior, M - Medial, AM - Anteromedial, AL - Anterolateral, MARMedial Anterior Rotary, LAR - Lateral Anterior Rotary, WR - With Recapture (not to be
confused with reduction), WOR - Without Recapture (not to be confused with reduction)
94
PRACTICE
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SIMMONS
AND GIBBS
ARA THERAPY
RELIEF
.....
""0
0)(I)
.s
ci
I
III
I
Before
MMI
40
Figure 1
Frequency of specific symptoms before treatment and
weighted frequency of the
same symptoms at maximum medical improvement.
Symptoms are numbered
sequentially as listed in
Table 2. Those symptoms
listed bilaterally in Table 2
are assigned separate numbers for each side. Symptoms at MMI were weighted
as absent, 0; improved, 0.5;
unchanged, I; and worse, 2.
ARA therapy produced a
statistically significant
decrease in the frequency of
these symptoms (X2 = 1345,
df= I, p<O.OOOl).
30
20
10
o
10
30
50
70
90
Symptom number
95% of the patients. Headaches after MMI were unchanged
in 1% of the patients, better in 33% of the patients and
.I::
....
uc~
:
C'"
::l
(I)
0)
'w
I""0
>.
II
N-N
N-WR
WR-WR
WR-WOR
WOR-WOR
~
.-..
80
II
I
I
60
40
MMI
20
Symptom
APRil
Figure 2
Frequency of specific symptoms before treatment and
-All
100
(I)
::R
!I
2005, Val.
23, NO. 2
PRACTICE
95
ARA THERAPY
RELIEF
SIMMONS
AND GIBBS
100
Figure 3
Relief of specific symptoms
at maximum medical
75
L
..
25
>
C0- 0
E
~ 50
<<D
D
....
improvement, as a percentage
of symptoms present pretreatment. Weights for symptom
frequencies at MMI as in
Figure 1. Disk status groups
as in Figure 2. Numerous
specific symptoms were completely relieved (100% ) in
several disk-status groups,
but only one in all patients
(mouth locked closed, present
in 18 patients). The appearance of worse symptoms at
MMI in the N-WR group was
the result of one patient with
sinusitis. See Figure 1 for
symptom numbering.
,'.
\-;
t"'
I
I
I
I
I
I
I
1
-25
All
N-N
N-WR
WR-WR
WR-WOR
WOR-WOR
10
I
I I
I. ,
I. ,
, .I
.,
I.
I.
"
.,
I.
II
30
50
70
90
Symptom number
96
PRACTICE
SIMMONS
AND GIBBS
ARA THERAPY
RELIEF
form an ear symptom profile. Earache is a common complaint of TMD patients and occurred 85% of the time. Ear
symptoms after MMI were the same in 5% of the patients,
better in 27.5 % of the patients, and eliminated in 67 % of
the patients. No ear symptoms were made worse.
Preauricular pain occurred in 60% of the patients.
Preauricular pain after MMI was unchanged in no patients,
better in 13% and absent in 87% of the patients.
TMJ pain group: Of the 43 patients reporting TMJ pain
pretreatment,
29 (67%) reported complete relief, 13
(30%) reported improvement, and one (2%) reported no
change at MMI. That is, TMJ pain was improved or elim-
PRACTICE
97
ARA THERAPY
SIMMONS
RELIEF
98
PRACTICE
AND GIBBS
SIMMONS
AND GIBBS
ARA THERAPY
4.
5.
6.
7.
8.
9.
10.
Conclusions
II.
Anterior repositioning appliance therapy for temporomandibular disorders provides significant relief for most
symptoms tracked in this study, for most patients.
Presence of many of the nine most frequent symptoms
(Table 6) suggests that TMJ disease should be strongly
considered in the differential diagnosis of facial pain.
Conversely, presence of only the least frequent symptoms (Table 7) should guide the differential diagnosis
away from TMD. The typical TMD patient has headaches,
mainly in the occipital, temporal and frontal region, earache, TMJ pain, pain and difficulty chewing food, back
of neck pain, and pain on opening and closing the mouth.
Since headache is the top complaint of TMD patients,
health care providers should include TMD in their differential diagnosis of headache patients.
After MMI, patients with both disks either normal or
recaptured showed the greatest symptomatic improvement (81-87%). Patients with at least one disk that did not
recapture showed less improvement (76%). This agrees
with previous reports showing that ARA therapy relieves
more symptoms in patients with disks that are recaptured
than those that do not. Overall, ARA therapy resulted in
either absence or improvement of 95% of symptoms present before treatment.
12.
References
1.
2.
3.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
RELIEF
PRACTICE
99