Aquinas University of Legazpi

College of Health Sciences

(PHARMACY INFORMATICS)
ACTIVITY 1
ICT SKILL ASSESSMENT
22 Name:_MARK RAVEN FRAILE___________________ Date _Nov. 14, 2016_Score___/40
Objective: Evaluate the basic proficiency in utilizing an alternate source of drug information.
Name of the Drug: ______Clonazepam_______________________________________
DESCRIPTION
IUPAC NAME

5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-1,4benzodiazepin-2-one

Clonazepam structure.
(n.d.). Retrieved
November 9, 2016, from
https://pubchem.ncbi.nl
m.nih.gov/image/imgsrv.
fcgi?cid=2802&t=l

CHEMICAL
STRUCTURE

TRADE NAMES
AND PRICES

SOURCES
DrugBank: Clonazepam.
(n.d.). Retrieved
November 9, 2016, from
http://www.drugbank.ca/
drugs/DB01068

Trade name
DEPANIL (0.5mg x
50s pack: 100.00
MRP ; 2mg x 30s
pack: 120.00 MRP)
DISOPAN (0.5mg x
100s pack: 200.00
MRP ; 2mg x 50s
pack: 200.00 MRP)
EPICLON (0.5mg x
50s pack: 100.00
MRP ; 2mg x 30s
pack: 120.00 MRP)
RIVOTRIL (0.5mg x
50s pack: 250.50
MRP ; 2mg x 30s
pack: 300.30 MRP)
XETRIL (0.5mg x
100s pack: 300.00 IP
; 2mg x 50s pack:

Manufacturer
RANGS PHARMA

INCEPTA
PHARMACEUTICALS LTD.

GENERAL
PHARMACEUTICALS LTD.

ROCHE BANGLADESH
LIMITED

BEXIMCO
PHARMACEUTICALS LTD.

Clonazepam trade name

& price. (n.d.). Retrieved
November 9, 2016, from
http://bddrugs.com/prod
uct5.php?idn=236

250.00 IP)
VARIOUS
DOSAGE FORMS
AND STRENGTHS

TABLET 1 mg ; 0.5 mg ; 2 mg ; 0.25 mg ; 0.125

mg
DROPS 2.5mg/ml drop ; 1.25mg/ml drop

CLINICAL
INDICATIONS

Controlling certain types of seizures in the treatment of

epilepsy and for the treatment of panic disorders. It may
also be used for other conditions as determined by your
doctor.

PREGNANCY
CATEGORY

Category D - There is positive evidence of human fetal

risk based on adverse reaction data from investigational
or marketing experience or studies in humans, but
potential benefits may warrant use in pregnant women
despite potential risks.

Clonazepam: Drug Uses,

Dosage, Side Effects Drugs.com. (n.d.). Retrieved
November 9, 2016, from
https://www.drugs.com/clonaz
epam.html

Clonazepam:
Indications, Side Effects,
Warnings - Drugs.com.
(n.d.). Retrieved
November 9, 2016, from
https://www.drugs.com/c
di/clonazepam.html
Clonazepam Dosage
Guide with Precautions Drugs.com. (n.d.).
Retrieved November 9,
2016, from
https://www.drugs.com/d
osage/clonazepam.html

Aquinas University of Legazpi

College of Health Sciences
(PHARMACY INFORMATICS)
ACTIVITY 1
ICT SKILL ASSESSMENT
22 Name:_MARK RAVEN FRAILE___________________ Date _Nov. 14, 2016_Score___/40
Objective: Evaluate the basic proficiency in utilizing an alternate source of drug information.
Name of the Drug: ______Pethidine_______________________________________
DESCRIPTION
IUPAC NAME

4-Piperidinecarboxylic acid, 1-metyl-4-phenyl-,

etyl ester

Pethidine - structure.
(n.d.). Retrieved
November 9, 2016, from
http://moldb.wishartlab.com/m
olecules/DBSALT000628/ima
ge.png

CHEMICAL
STRUCTURE

TRADE NAMES
AND PRICES

SOURCES
Pethidine - Drugs.com.
(n.d.). Retrieved
November 9, 2016, from
https://www.drugs.com/i
nternational/pethidine.ht
ml

Trade name
PETHIDINE (

18)

ALODAN

CLOPEDIN
DOLARGAN

Manufacturer
NEON LABORATORIES LTD.

G.L PHARMA, AUSTRIA

Pethidine (Pethidine)
Price List. (n.d.).
Retrieved November 13,
2016, from
http://www.medindia.net
/drugprice/pethidine/pet
hidine.htm

KIMIA, FARMA, INDONESIA

SANOFI-AVENTIS,
HUNGARY

Pethidine - Drugs.com.
(n.d.). Retrieved
November 13, 2016,

LYDOL

SOPHARMA, BULGARIA

from
https://www.drugs.com/int
ernational/pethidine.html
VARIOUS
DOSAGE FORMS
AND STRENGTHS

Intravenous
Adjunct to anaesthesia
Adult: As hydrochloride: 10-25 mg by slow IV inj.
Oral
Moderate to severe acute pain
Adult: As hydrochloride: 50-150 mg every 4 hr if needed.
Child: As hydrochloride: Children 2 mth to 12 yr: 0.5-2 mg/kg;
12-18 yr: 50-100 mg. Repeat dose every 4-6 hr if necessary.
Elderly: As hydrochloride: 50 mg every 4 hr.
Parenteral
Preoperative medication
Adult: As hydrochloride: 25-100 mg IM/SC given 1 hr before
surgery.
Child: As hydrochloride: 1-2 mg/kg given IM 1 hr before
surgery.
Parenteral
Moderate to severe acute pain
Adult: As hydrochloride: 25-100 mg IM/SC inj or 25-50 mg by
slow IV inj repeated after 4 hr.
Child: As hydrochloride: SC/IM: 2 mth to 12 yr: 0.5-2 mg/kg;
12-18 yr: 20-100 mg. Repeat dose every 4-6 hr if needed. IV
inj: Neonates and children 12 yr: 0.5-1 mg/kg IV inj every 1012 hr if needed in those up to 2 mth and every 4-6 hr if needed
in older children. 12-18 yr: 25-50 mg every 4-6 hr if needed.
Alternatively, 1 mth: Loading dose: 1 mg/kg by IV inj
followed by 100-400 mcg/kg/hr via continuous IV infusion
adjusted according to response.
Elderly: 25 mg every 4 hr.
Parenteral
Postoperative pain
Adult: As hydrochloride: 25-100 mg IM/SC inj every 2-3 hr if
necessary.
Child: As hydrochloride: 0.5-2 mg/kg IM every 2-3 hr if
necessary.
Parenteral
Obstetric analgesia
Adult: As hydrochloride: 50-100 mg by IM/SC inj as soon as
contractions occur at regular intervals; repeat after 1-3 hr if
needed. Max: 400 mg in 24 hr.

Pethidine (Pethidine)
Retrieved November 13,
2016, from
https://www.mims.com/philipp
ines/drug/info/pethidine/?
type=brief&mtype=generic

CLINICAL
INDICATIONS

Adult : PO Moderate to severe acute pain 50-150 mg 4 hrly. IV

Adjunct to anesth 10-25 mg. IV/IM/SC
Moderate to severe acute pain 25-100 mg IM/SC inj or 25-50
mg by slow IV inj repeated after 4 hr. IM/SC Obstetric
analgesia 50-100 mg as soon as contractions occur at regular
intervals; repeat after 1-3 hr if needed. Max: 400 mg/24 hr.

Pethidine (Pethidine)
Retrieved November 13,
2016, from
https://www.mims.com/philipp
ines/drug/info/pethidine/?
type=brief&mtype=generic

Pre-op medication 25-100 mg 1 hr pre-op.

Post-op pain 25-100 mg 2-3 hrly if needed.
PREGNANCY
CATEGORY

Pregnancy category: B; use for prolonged periods or near

term not established
Lactation: Drug excreted in breast milk

Pethidine (Pethidine)
Retrieved November 13,
2016, from
http://reference.medscape.com/
drug/demerol-meperidine343315#6